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DNA Superresolution Structure of Reed-Sternberg Cells Differs Between Long Lasting Remission Versus Relapsing Hodgkin's Lymphoma Patients.

Righolt CH, Knecht H, Mai S.

J Cell Biochem. 2015 Dec 7. doi: 10.1002/jcb.25456. [Epub ahead of print]


Dynamic changes of the luminal and mucosa-associated gut microbiota during and after antibiotic therapy with paromomycin.

Heinsen FA, Knecht H, Neulinger SC, Schmitz RA, Knecht C, Kühbacher T, Rosenstiel PC, Schreiber S, Friedrichs AK, Ott SJ.

Gut Microbes. 2015 Jul 4;6(4):243-54. doi: 10.1080/19490976.2015.1062959.


High-Throughput, Amplicon-Based Sequencing of the CREBBP Gene as a Tool to Develop a Universal Platform-Independent Assay.

Fuellgrabe MW, Herrmann D, Knecht H, Kuenzel S, Kneba M, Pott C, Brüggemann M.

PLoS One. 2015 Jun 9;10(6):e0129195. doi: 10.1371/journal.pone.0129195. eCollection 2015.


LMP1 mediates multinuclearity through downregulation of shelterin proteins and formation of telomeric aggregates.

Lajoie V, Lemieux B, Sawan B, Lichtensztejn D, Lichtensztejn Z, Wellinger R, Mai S, Knecht H.

Blood. 2015 Mar 26;125(13):2101-10. doi: 10.1182/blood-2014-08-594176. Epub 2015 Jan 7.


Rapid separation of mononuclear hodgkin from multinuclear reed-sternberg cells.

Kongruttanachok N, Cayre YE, Knecht H, Mai S.

Lab Hematol. 2014 Mar 1;20(1):2-6. doi: 10.1532/LH96.12023.


Differences in nuclear DNA organization between lymphocytes, Hodgkin and Reed-Sternberg cells revealed by structured illumination microscopy.

Righolt CH, Guffei A, Knecht H, Young IT, Stallinga S, van Vliet LJ, Mai S.

J Cell Biochem. 2014 Aug;115(8):1441-8. doi: 10.1002/jcb.24800.


Effects of β-lactam antibiotics and fluoroquinolones on human gut microbiota in relation to Clostridium difficile associated diarrhea.

Knecht H, Neulinger SC, Heinsen FA, Knecht C, Schilhabel A, Schmitz RA, Zimmermann A, dos Santos VM, Ferrer M, Rosenstiel PC, Schreiber S, Friedrichs AK, Ott SJ.

PLoS One. 2014 Feb 28;9(2):e89417. doi: 10.1371/journal.pone.0089417. eCollection 2014.


Salinity affects compositional traits of epibacterial communities on the brown macroalga Fucus vesiculosus.

Stratil SB, Neulinger SC, Knecht H, Friedrichs AK, Wahl M.

FEMS Microbiol Ecol. 2014 May;88(2):272-9. doi: 10.1111/1574-6941.12292. Epub 2014 Mar 10.


Differential effects of antibiotic therapy on the structure and function of human gut microbiota.

Pérez-Cobas AE, Artacho A, Knecht H, Ferrús ML, Friedrichs A, Ott SJ, Moya A, Latorre A, Gosalbes MJ.

PLoS One. 2013 Nov 25;8(11):e80201. doi: 10.1371/journal.pone.0080201. eCollection 2013.


Genomic Instability: The Driving Force behind Refractory/Relapsing Hodgkin's Lymphoma.

Knecht H, Righolt C, Mai S.

Cancers (Basel). 2013 Jun 5;5(2):714-25. doi: 10.3390/cancers5020714.


Functional consequences of microbial shifts in the human gastrointestinal tract linked to antibiotic treatment and obesity.

Hernández E, Bargiela R, Diez MS, Friedrichs A, Pérez-Cobas AE, Gosalbes MJ, Knecht H, Martínez-Martínez M, Seifert J, von Bergen M, Artacho A, Ruiz A, Campoy C, Latorre A, Ott SJ, Moya A, Suárez A, Martins dos Santos VA, Ferrer M.

Gut Microbes. 2013 Jul-Aug;4(4):306-15. doi: 10.4161/gmic.25321. Epub 2013 Jun 12.


Temperature-driven shifts in the epibiotic bacterial community composition of the brown macroalga Fucus vesiculosus.

Stratil SB, Neulinger SC, Knecht H, Friedrichs AK, Wahl M.

Microbiologyopen. 2013 Apr;2(2):338-49. doi: 10.1002/mbo3.79. Epub 2013 Mar 13.


Gut microbiota disturbance during antibiotic therapy: a multi-omic approach.

Pérez-Cobas AE, Gosalbes MJ, Friedrichs A, Knecht H, Artacho A, Eismann K, Otto W, Rojo D, Bargiela R, von Bergen M, Neulinger SC, Däumer C, Heinsen FA, Latorre A, Barbas C, Seifert J, dos Santos VM, Ott SJ, Ferrer M, Moya A.

Gut. 2013 Nov;62(11):1591-601. doi: 10.1136/gutjnl-2012-303184. Epub 2012 Dec 12.


Three-dimensional Telomere Signatures of Hodgkin- and Reed-Sternberg Cells at Diagnosis Identify Patients with Poor Response to Conventional Chemotherapy.

Knecht H, Kongruttanachok N, Sawan B, Brossard J, Prévost S, Turcotte E, Lichtensztejn Z, Lichtensztejn D, Mai S.

Transl Oncol. 2012 Aug;5(4):269-77. Epub 2012 Aug 1.


Effects of probiotics and antibiotics on the intestinal homeostasis in a computer controlled model of the large intestine.

Rehman A, Heinsen FA, Koenen ME, Venema K, Knecht H, Hellmig S, Schreiber S, Ott SJ.

BMC Microbiol. 2012 Mar 27;12:47. doi: 10.1186/1471-2180-12-47.


Nuclear remodeling as a mechanism for genomic instability in cancer.

Gadji M, Vallente R, Klewes L, Righolt C, Wark L, Kongruttanachok N, Knecht H, Mai S.

Adv Cancer Res. 2011;112:77-126. doi: 10.1016/B978-0-12-387688-1.00004-1. Review.


3D nuclear organization of telomeres in the Hodgkin cell lines U-HO1 and U-HO1-PTPN1: PTPN1 expression prevents the formation of very short telomeres including "t-stumps".

Knecht H, Brüderlein S, Wegener S, Lichtensztejn D, Lichtensztejn Z, Lemieux B, Möller P, Mai S.

BMC Cell Biol. 2010 Dec 14;11:99. doi: 10.1186/1471-2121-11-99.


3D imaging of telomeres and nuclear architecture: An emerging tool of 3D nano-morphology-based diagnosis.

Knecht H, Mai S.

J Cell Physiol. 2011 Apr;226(4):859-67. doi: 10.1002/jcp.22425. Review.


Dynamic chromosomal rearrangements in Hodgkin's lymphoma are due to ongoing three-dimensional nuclear remodeling and breakage-bridge-fusion cycles.

Guffei A, Sarkar R, Klewes L, Righolt C, Knecht H, Mai S.

Haematologica. 2010 Dec;95(12):2038-46. doi: 10.3324/haematol.2010.030171. Epub 2010 Sep 7.


3D structural and functional characterization of the transition from Hodgkin to Reed-Sternberg cells.

Knecht H, Brüderlein S, Mai S, Möller P, Sawan B.

Ann Anat. 2010 Sep 20;192(5):302-8. doi: 10.1016/j.aanat.2010.07.006. Epub 2010 Aug 6. Review.

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