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Items: 1 to 20 of 102

1.

A novel KLF6-Rho GTPase axis regulates hepatocellular carcinoma cell migration and dissemination.

Ahronian LG, Zhu LJ, Chen YW, Chu HC, Klimstra DS, Lewis BC.

Oncogene. 2016 Feb 15. doi: 10.1038/onc.2016.2. [Epub ahead of print]

2.

Well-Differentiated Neuroendocrine Tumors with a Morphologically Apparent High-Grade Component: A Pathway Distinct from Poorly Differentiated Neuroendocrine Carcinomas.

Tang LH, Untch BR, Reidy DL, O'Reilly E, Dhall D, Jih L, Basturk O, Allen PJ, Klimstra DS.

Clin Cancer Res. 2016 Feb 15;22(4):1011-7. doi: 10.1158/1078-0432.CCR-15-0548. Epub 2015 Oct 19. Erratum in: Clin Cancer Res. 2016 Aug 15;22(16):4273.

3.

Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells.

Oikawa T, Wauthier E, Dinh TA, Selitsky SR, Reyna-Neyra A, Carpino G, Levine R, Cardinale V, Klimstra D, Gaudio E, Alvaro D, Carrasco N, Sethupathy P, Reid LM.

Nat Commun. 2015 Oct 6;6:8070. doi: 10.1038/ncomms9070.

4.

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients.

Sausen M, Phallen J, Adleff V, Jones S, Leary RJ, Barrett MT, Anagnostou V, Parpart-Li S, Murphy D, Kay Li Q, Hruban CA, Scharpf R, White JR, O'Dwyer PJ, Allen PJ, Eshleman JR, Thompson CB, Klimstra DS, Linehan DC, Maitra A, Hruban RH, Diaz LA Jr, Von Hoff DD, Johansen JS, Drebin JA, Velculescu VE.

Nat Commun. 2015 Jul 7;6:7686. doi: 10.1038/ncomms8686.

5.

Prospective evaluation of 18F-fluorodeoxyglucose positron emission tomography in patients receiving hepatic arterial and systemic chemotherapy for unresectable colorectal liver metastases.

Correa-Gallego C, Gavane S, Grewal R, Cercek A, Klimstra DS, Gewirtz AN, Kingham TP, Fong Y, DeMatteo RP, Allen PJ, Jarnagin WR, Kemeny N, D'Angelica MI.

HPB (Oxford). 2015 Jul;17(7):644-50. doi: 10.1111/hpb.12421. Epub 2015 May 23.

6.

Sequencing of 279 cancer genes in ampullary carcinoma reveals trends relating to histologic subtypes and frequent amplification and overexpression of ERBB2 (HER2).

Hechtman JF, Liu W, Sadowska J, Zhen L, Borsu L, Arcila ME, Won HH, Shah RH, Berger MF, Vakiani E, Shia J, Klimstra DS.

Mod Pathol. 2015 Aug;28(8):1123-9. doi: 10.1038/modpathol.2015.57. Epub 2015 May 15.

7.

Prognostic factors in myoepithelial carcinoma of salivary glands: a clinicopathologic study of 48 cases.

Kong M, Drill EN, Morris L, West L, Klimstra D, Gonen M, Ghossein R, Katabi N.

Am J Surg Pathol. 2015 Jul;39(7):931-8. doi: 10.1097/PAS.0000000000000452.

8.

Early detection of sporadic pancreatic cancer: summative review.

Chari ST, Kelly K, Hollingsworth MA, Thayer SP, Ahlquist DA, Andersen DK, Batra SK, Brentnall TA, Canto M, Cleeter DF, Firpo MA, Gambhir SS, Go VL, Hines OJ, Kenner BJ, Klimstra DS, Lerch MM, Levy MJ, Maitra A, Mulvihill SJ, Petersen GM, Rhim AD, Simeone DM, Srivastava S, Tanaka M, Vinik AI, Wong D.

Pancreas. 2015 Jul;44(5):693-712. doi: 10.1097/MPA.0000000000000368. Review.

9.

The p53R172H mutant does not enhance hepatocellular carcinoma development and progression.

Ahronian LG, Driscoll DR, Klimstra DS, Lewis BC.

PLoS One. 2015 Apr 17;10(4):e0123816. doi: 10.1371/journal.pone.0123816. eCollection 2015.

10.

GNAS and KRAS Mutations Define Separate Progression Pathways in Intraductal Papillary Mucinous Neoplasm-Associated Carcinoma.

Tan MC, Basturk O, Brannon AR, Bhanot U, Scott SN, Bouvier N, LaFemina J, Jarnagin WR, Berger MF, Klimstra D, Allen PJ.

J Am Coll Surg. 2015 May;220(5):845-54.e1. doi: 10.1016/j.jamcollsurg.2014.11.029. Epub 2015 Feb 11.

11.

The high-grade (WHO G3) pancreatic neuroendocrine tumor category is morphologically and biologically heterogenous and includes both well differentiated and poorly differentiated neoplasms.

Basturk O, Yang Z, Tang LH, Hruban RH, Adsay V, McCall CM, Krasinskas AM, Jang KT, Frankel WL, Balci S, Sigel C, Klimstra DS.

Am J Surg Pathol. 2015 May;39(5):683-90. doi: 10.1097/PAS.0000000000000408.

12.

Prognostic factors in fibrolamellar hepatocellular carcinoma in young people.

Darcy DG, Malek MM, Kobos R, Klimstra DS, DeMatteo R, La Quaglia MP.

J Pediatr Surg. 2015 Jan;50(1):153-6. doi: 10.1016/j.jpedsurg.2014.10.039. Epub 2014 Dec 10.

13.

Organoid models of human and mouse ductal pancreatic cancer.

Boj SF, Hwang CI, Baker LA, Chio II, Engle DD, Corbo V, Jager M, Ponz-Sarvise M, Tiriac H, Spector MS, Gracanin A, Oni T, Yu KH, van Boxtel R, Huch M, Rivera KD, Wilson JP, Feigin ME, Öhlund D, Handly-Santana A, Ardito-Abraham CM, Ludwig M, Elyada E, Alagesan B, Biffi G, Yordanov GN, Delcuze B, Creighton B, Wright K, Park Y, Morsink FH, Molenaar IQ, Borel Rinkes IH, Cuppen E, Hao Y, Jin Y, Nijman IJ, Iacobuzio-Donahue C, Leach SD, Pappin DJ, Hammell M, Klimstra DS, Basturk O, Hruban RH, Offerhaus GJ, Vries RG, Clevers H, Tuveson DA.

Cell. 2015 Jan 15;160(1-2):324-38. doi: 10.1016/j.cell.2014.12.021. Epub 2014 Dec 31.

14.

Immunohistochemical detection of the BRAF V600E mutant protein in colorectal neoplasms.

Vakiani E, Yaeger R, Brooke S, Zhou Y, Klimstra DS, Shia J.

Appl Immunohistochem Mol Morphol. 2015 Jul;23(6):438-43. doi: 10.1097/PAI.0000000000000116.

15.

Adenocarcinoma of the pancreas.

Hruban RH, Klimstra DS.

Semin Diagn Pathol. 2014 Nov;31(6):443-51. doi: 10.1053/j.semdp.2014.08.004. Epub 2014 Sep 2. Review.

16.

Pathology and genetics of pancreatic neoplasms with acinar differentiation.

Wood LD, Klimstra DS.

Semin Diagn Pathol. 2014 Nov;31(6):491-7. doi: 10.1053/j.semdp.2014.08.003. Epub 2014 Oct 2.

17.

Interobserver agreement for detection of malignant features of intraductal papillary mucinous neoplasms of the pancreas on MDCT.

Do RK, Katz SS, Gollub MJ, Li J, LaFemina J, Zabor EC, Moskowitz CS, Klimstra DS, Allen PJ.

AJR Am J Roentgenol. 2014 Nov;203(5):973-9. doi: 10.2214/AJR.13.11490.

18.

From the liver to the foot: a case of systemic embolism and acrometastasis in hepatocellular carcinoma.

Abu-Zeinah G, Owen D, Prieto-Granada C, Rekhtman N, Klimstra D, Gupta D, Harding J, Abou-Alfa GK.

Gastrointest Cancer Res. 2014 May;7(3-4):103-7. No abstract available.

19.

Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.

Akkari L, Gocheva V, Kester JC, Hunter KE, Quick ML, Sevenich L, Wang HW, Peters C, Tang LH, Klimstra DS, Reinheckel T, Joyce JA.

Genes Dev. 2014 Oct 1;28(19):2134-50. doi: 10.1101/gad.249599.114.

20.

A single-arm, nonrandomized phase II trial of neoadjuvant gemcitabine and oxaliplatin in patients with resectable pancreas adenocarcinoma.

OʼReilly EM, Perelshteyn A, Jarnagin WR, Schattner M, Gerdes H, Capanu M, Tang LH, LaValle J, Winston C, DeMatteo RP, DʼAngelica M, Kurtz RC, Abou-Alfa GK, Klimstra DS, Lowery MA, Brennan MF, Coit DG, Reidy DL, Kingham TP, Allen PJ.

Ann Surg. 2014 Jul;260(1):142-8. doi: 10.1097/SLA.0000000000000251.

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