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Results: 1 to 20 of 285

1.

Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities.

Kagawa S, Natsuizaka M, Whelan KA, Facompre N, Naganuma S, Ohashi S, Kinugasa H, Egloff AM, Basu D, Gimotty PA, Klein-Szanto AJ, Bass AJ, Wong KK, Diehl JA, Rustgi AK, Nakagawa H.

Oncogene. 2014 Jun 16;0. doi: 10.1038/onc.2014.169. [Epub ahead of print]

PMID:
24931169
[PubMed - as supplied by publisher]
2.

Enhanced aggressiveness of benzopyrene-induced squamous carcinomas in transgenic mice overexpressing the proprotein convertase PACE4 (PCSK6).

Bassi DE, Cenna J, Zhang J, Cukierman E, Klein-Szanto AJ.

Mol Carcinog. 2014 May 21. doi: 10.1002/mc.22183. [Epub ahead of print]

PMID:
24845697
[PubMed - as supplied by publisher]
3.

IGFBP3 promotes esophageal cancer growth by suppressing oxidative stress in hypoxic tumor microenvironment.

Natsuizaka M, Kinugasa H, Kagawa S, Whelan KA, Naganuma S, Subramanian H, Chang S, Nakagawa KJ, Rustgi NL, Kita Y, Natsugoe S, Basu D, Gimotty PA, Klein-Szanto AJ, Diehl JA, Nakagawa H.

Am J Cancer Res. 2014 Jan 15;4(1):29-41. eCollection 2014.

PMID:
24482736
[PubMed]
Free PMC Article
4.

Regulation of HIF-1 alpha by the proprotein convertases furin and PC7 in human squamous carcinoma cells.

Fu J, Zhang J, Gong Y, Testa CL, Klein-Szanto AJ.

Mol Carcinog. 2014 Jan 16. doi: 10.1002/mc.22131. [Epub ahead of print]

PMID:
24436242
[PubMed - as supplied by publisher]
5.

Tumor suppressor alterations cooperate to drive aggressive mesotheliomas with enriched cancer stem cells via a p53-miR-34a-c-Met axis.

Menges CW, Kadariya Y, Altomare D, Talarchek J, Neumann-Domer E, Wu Y, Xiao GH, Shapiro IM, Kolev VN, Pachter JA, Klein-Szanto AJ, Testa JR.

Cancer Res. 2014 Feb 15;74(4):1261-71. doi: 10.1158/0008-5472.CAN-13-2062. Epub 2013 Dec 26.

PMID:
24371224
[PubMed - indexed for MEDLINE]
6.

Comparative secretome analysis of epithelial and mesenchymal subpopulations of head and neck squamous cell carcinoma identifies S100A4 as a potential therapeutic target.

Rasanen K, Sriswasdi S, Valiga A, Tang HY, Zhang G, Perego M, Somasundaram R, Li L, Speicher K, Klein-Szanto AJ, Basu D, Rustgi AK, Speicher DW, Herlyn M.

Mol Cell Proteomics. 2013 Dec;12(12):3778-92. doi: 10.1074/mcp.M113.029587. Epub 2013 Sep 13.

PMID:
24037664
[PubMed - in process]
7.

Periostin cooperates with mutant p53 to mediate invasion through the induction of STAT1 signaling in the esophageal tumor microenvironment.

Wong GS, Lee JS, Park YY, Klein-Szanto AJ, Waldron TJ, Cukierman E, Herlyn M, Gimotty P, Nakagawa H, Rustgi AK.

Oncogenesis. 2013 Aug 5;2:e59. doi: 10.1038/oncsis.2013.17.

PMID:
23917221
[PubMed]
Free PMC Article
8.

Psychosocial functioning and vascular endothelial growth factor in patients with head and neck cancer.

Fang CY, Egleston BL, Ridge JA, Lango MN, Bovbjerg DH, Studts JL, Burtness BA, Einarson MB, Klein-Szanto AJ.

Head Neck. 2013 Jun 26. doi: 10.1002/hed.23421. [Epub ahead of print]

PMID:
23804308
[PubMed - as supplied by publisher]
9.

Inflammatory breast cancer (IBC): clues for targeted therapies.

Fernandez SV, Robertson FM, Pei J, Aburto-Chumpitaz L, Mu Z, Chu K, Alpaugh RK, Huang Y, Cao Y, Ye Z, Cai KQ, Boley KM, Klein-Szanto AJ, Devarajan K, Addya S, Cristofanilli M.

Breast Cancer Res Treat. 2013 Jul;140(1):23-33. doi: 10.1007/s10549-013-2600-4. Epub 2013 Jun 21.

PMID:
23784380
[PubMed - indexed for MEDLINE]
10.

IMP1 promotes tumor growth, dissemination and a tumor-initiating cell phenotype in colorectal cancer cell xenografts.

Hamilton KE, Noubissi FK, Katti PS, Hahn CM, Davey SR, Lundsmith ET, Klein-Szanto AJ, Rhim AD, Spiegelman VS, Rustgi AK.

Carcinogenesis. 2013 Nov;34(11):2647-54. doi: 10.1093/carcin/bgt217. Epub 2013 Jun 12.

PMID:
23764754
[PubMed - indexed for MEDLINE]
11.

Enhanced UV-induced skin carcinogenesis in transgenic mice overexpressing proprotein convertases.

Fu J, Bassi DE, Zhang J, Li T, Cai KQ, Testa CL, Nicolas E, Klein-Szanto AJ.

Neoplasia. 2013 Feb;15(2):169-79.

PMID:
23441131
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion.

Do TV, Xiao F, Bickel LE, Klein-Szanto AJ, Pathak HB, Hua X, Howe C, O'Brien SW, Maglaty M, Ecsedy JA, Litwin S, Golemis EA, Schilder RJ, Godwin AK, Connolly DC.

Oncogene. 2014 Jan 30;33(5):539-49. doi: 10.1038/onc.2012.632. Epub 2013 Jan 21.

PMID:
23334327
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice.

Little JL, Serzhanova V, Izumchenko E, Egleston BL, Parise E, Klein-Szanto AJ, Loudon G, Shubina M, Seo S, Kurokawa M, Ochs MF, Golemis EA.

Oncogene. 2014 Jan 23;33(4):411-20. doi: 10.1038/onc.2012.607. Epub 2013 Jan 14.

PMID:
23318423
[PubMed - indexed for MEDLINE]
14.

Elk-1 phosphorylated at threonine-417 is present in diverse cancers and correlates with differentiation grade of colonic adenocarcinoma.

Morris JF, Sul JY, Kim MS, Klein-Szanto AJ, Schochet T, Rustgi A, Eberwine JH.

Hum Pathol. 2013 May;44(5):766-76. doi: 10.1016/j.humpath.2012.08.001. Epub 2012 Oct 29.

PMID:
23114923
[PubMed - indexed for MEDLINE]
15.

Optical imaging of periostin enables early endoscopic detection and characterization of esophageal cancer in mice.

Wong GS, Habibollahi P, Heidari P, Lee JS, Klein-Szanto AJ, Waldron TJ, Gimotty P, Nakagawa H, Taylor PR, Wang TC, Mahmood U, Rustgi AK.

Gastroenterology. 2013 Feb;144(2):294-7. doi: 10.1053/j.gastro.2012.10.030. Epub 2012 Oct 22.

PMID:
23085486
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

p21-Activated kinase 1 is required for efficient tumor formation and progression in a Ras-mediated skin cancer model.

Chow HY, Jubb AM, Koch JN, Jaffer ZM, Stepanova D, Campbell DA, Duron SG, O'Farrell M, Cai KQ, Klein-Szanto AJ, Gutkind JS, Hoeflich KP, Chernoff J.

Cancer Res. 2012 Nov 15;72(22):5966-75. doi: 10.1158/0008-5472.CAN-12-2246. Epub 2012 Sep 14.

PMID:
22983922
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Notch receptor inhibition reveals the importance of cyclin D1 and Wnt signaling in invasive esophageal squamous cell carcinoma.

Naganuma S, Whelan KA, Natsuizaka M, Kagawa S, Kinugasa H, Chang S, Subramanian H, Rhoades B, Ohashi S, Itoh H, Herlyn M, Diehl JA, Gimotty PA, Klein-Szanto AJ, Nakagawa H.

Am J Cancer Res. 2012;2(4):459-75. Epub 2012 Jun 28.

PMID:
22860235
[PubMed]
Free PMC Article
18.

Transgenic overexpression of the proprotein convertase furin enhances skin tumor growth.

Fu J, Bassi DE, Zhang J, Li T, Nicolas E, Klein-Szanto AJ.

Neoplasia. 2012 Apr;14(4):271-82.

PMID:
22577343
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Dissecting Pin1 and phospho-pRb regulation.

Rizzolio F, Caligiuri I, Lucchetti C, Fratamico R, Tomei V, Gallo G, Agelan A, Ferrari G, Toffoli G, Klein-Szanto AJ, Giordano A.

J Cell Physiol. 2013 Jan;228(1):73-7. doi: 10.1002/jcp.24107.

PMID:
22553088
[PubMed - indexed for MEDLINE]
20.

POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation.

Pero R, Palmieri D, Angrisano T, Valentino T, Federico A, Franco R, Lembo F, Klein-Szanto AJ, Del Vecchio L, Montanaro D, Keller S, Arra C, Papadopoulou V, Wagner SD, Croce CM, Fusco A, Chiariotti L, Fedele M.

J Biol Chem. 2012 May 25;287(22):18308-17. doi: 10.1074/jbc.M112.346270. Epub 2012 Apr 9.

PMID:
22493480
[PubMed - indexed for MEDLINE]
Free PMC Article

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