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Results: 1 to 20 of 267

1.

C-terminal cleavage of human Foxp3 at a Proprotein Convertase motif abrogates its suppressive function.

Elhage R, Cheraï M, Levacher B, Darrasse-Jeze G, Baillou C, Zhao X, Khatib AM, Piaggio E, Klatzmann D.

Scand J Immunol. 2015 Feb 13. doi: 10.1111/sji.12275. [Epub ahead of print]

PMID:
25683871
[PubMed - as supplied by publisher]
2.

Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients.

Rosenzwajg M, Churlaud G, Mallone R, Six A, Dérian N, Chaara W, Lorenzon R, Long SA, Buckner JH, Afonso G, Pham HP, Hartemann A, Yu A, Pugliese A, Malek TR, Klatzmann D.

J Autoimmun. 2015 Jan 26. pii: S0896-8411(15)00002-5. doi: 10.1016/j.jaut.2015.01.001. [Epub ahead of print]

PMID:
25634360
[PubMed - as supplied by publisher]
3.

Th1 and Th17 cytokines drive Takayasu Arteritis inflammation.

Saadoun D, Garrido M, Comarmond C, Desbois AC, Domont F, Savey L, Terrier B, Geri G, Rosenzwajg M, Klatzmann D, Fourret P, Cluzel P, Chiche L, Gaudric J, Koskas F, Cacoub P.

Arthritis Rheumatol. 2015 Jan 20. doi: 10.1002/art.39037. [Epub ahead of print]

PMID:
25604824
[PubMed - as supplied by publisher]
4.

Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25.

Hannani D, Vétizou M, Enot D, Rusakiewicz S, Chaput N, Klatzmann D, Desbois M, Jacquelot N, Vimond N, Chouaib S, Mateus C, Allison JP, Ribas A, Wolchok JD, Yuan J, Wong P, Postow M, Mackiewicz A, Mackiewicz J, Schadendorff D, Jaeger D, Korman AJ, Bahjat K, Maio M, Calabro L, Teng MW, Smyth MJ, Eggermont A, Robert C, Kroemer G, Zitvogel L.

Cell Res. 2015 Feb;25(2):208-24. doi: 10.1038/cr.2015.3. Epub 2015 Jan 13.

PMID:
25582080
[PubMed - in process]
5.

Selective IL-2 responsiveness of regulatory T cells through multiple intrinsic mechanisms support the use of low-dose IL-2 therapy in Type-1 diabetes.

Yu A, Snowhite I, Vendrame F, Rosenzwajg M, Klatzmann D, Pugliese A, Malek TR.

Diabetes. 2015 Jan 9. pii: db141322. [Epub ahead of print]

PMID:
25576057
[PubMed - as supplied by publisher]
6.

Interleukin 2 in the pathogenesis and therapy of type 1 diabetes.

Rosenzwajg M, Churlaud G, Hartemann A, Klatzmann D.

Curr Diab Rep. 2014 Dec;14(12):553. doi: 10.1007/s11892-014-0553-6.

PMID:
25344788
[PubMed - in process]
7.

Interleukin-5-producing group 2 innate lymphoid cells control eosinophilia induced by interleukin-2 therapy.

Van Gool F, Molofsky AB, Morar MM, Rosenzwajg M, Liang HE, Klatzmann D, Locksley RM, Bluestone JA.

Blood. 2014 Dec 4;124(24):3572-6. doi: 10.1182/blood-2014-07-587493. Epub 2014 Oct 16.

PMID:
25323825
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Regulatory T-cells in pregnancy: historical perspective, state of the art, and burning questions.

Ruocco MG, Chaouat G, Florez L, Bensussan A, Klatzmann D.

Front Immunol. 2014 Aug 21;5:389. doi: 10.3389/fimmu.2014.00389. eCollection 2014. Review.

PMID:
25191324
[PubMed]
Free PMC Article
9.

A novel strategy for molecular signature discovery based on independent component analysis.

Pham HP, Dérian N, Chaara W, Bellier B, Klatzmann D, Six A.

Int J Data Min Bioinform. 2014;9(3):277-304.

PMID:
25163169
[PubMed - indexed for MEDLINE]
10.

Lymphodepletion followed by infusion of suicide gene-transduced donor lymphocytes to safely enhance their antitumor effect: a phase I/II study.

Maury S, Rosenzwajg M, Redjoul R, Marcais A, Xhaard A, Cherai M, Cabanne L, Churlaud G, Suarez F, Socié G, Gregoire L, Debbache K, Bernard C, Beaumont JL, Azar N, Boyer O, Roudot-Thoraval F, Cohen JL, Cordonnier C, Lemoine FM, Klatzmann D.

Leukemia. 2014 Dec;28(12):2406-10. doi: 10.1038/leu.2014.237. Epub 2014 Aug 8. No abstract available.

PMID:
25102947
[PubMed - in process]
11.

Epigenetic regulations in the IFNγ signalling pathway: IFNγ-mediated MHC class I upregulation on tumour cells is associated with DNA demethylation of antigen-presenting machinery genes.

Vlková V, Štěpánek I, Hrušková V, Šenigl F, Mayerová V, Šrámek M, Šímová J, Bieblová J, Indrová M, Hejhal T, Dérian N, Klatzmann D, Six A, Reiniš M.

Oncotarget. 2014 Aug 30;5(16):6923-35.

PMID:
25071011
[PubMed - in process]
Free PMC Article
12.

Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial.

Hartemann A, Bensimon G, Payan CA, Jacqueminet S, Bourron O, Nicolas N, Fonfrede M, Rosenzwajg M, Bernard C, Klatzmann D.

Lancet Diabetes Endocrinol. 2013 Dec;1(4):295-305. doi: 10.1016/S2213-8587(13)70113-X. Epub 2013 Oct 8.

PMID:
24622415
[PubMed - indexed for MEDLINE]
13.

Th1 response and systemic treg deficiency in inclusion body myositis.

Allenbach Y, Chaara W, Rosenzwajg M, Six A, Prevel N, Mingozzi F, Wanschitz J, Musset L, Charuel JL, Eymard B, Salomon B, Duyckaerts C, Maisonobe T, Dubourg O, Herson S, Klatzmann D, Benveniste O.

PLoS One. 2014 Mar 4;9(3):e88788. doi: 10.1371/journal.pone.0088788. eCollection 2014.

PMID:
24594700
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Sustained stimulation and expansion of Tregs by IL2 control autoimmunity without impairing immune responses to infection, vaccination and cancer.

Churlaud G, Jimenez V, Ruberte J, Amadoudji Zin M, Fourcade G, Gottrand G, Casana E, Lambrecht B, Bellier B, Piaggio E, Bosch F, Klatzmann D.

Clin Immunol. 2014 Apr;151(2):114-26. doi: 10.1016/j.clim.2014.02.003. Epub 2014 Feb 19.

PMID:
24576619
[PubMed - indexed for MEDLINE]
15.

CD21(-/low) marginal zone B cells highly express Fc receptor-like 5 protein and are killed by anti-Fc receptor-like 5 immunotoxins in hepatitis C virus-associated mixed cryoglobulinemia vasculitis.

Terrier B, Nagata S, Ise T, Rosenzwajg M, Pastan I, Klatzmann D, Saadoun D, Cacoub P.

Arthritis Rheumatol. 2014 Feb;66(2):433-43. doi: 10.1002/art.38222.

PMID:
24504816
[PubMed - indexed for MEDLINE]
16.

Enveloped virus-like particle expression of human cytomegalovirus glycoprotein B antigen induces antibodies with potent and broad neutralizing activity.

Kirchmeier M, Fluckiger AC, Soare C, Bozic J, Ontsouka B, Ahmed T, Diress A, Pereira L, Schödel F, Plotkin S, Dalba C, Klatzmann D, Anderson DE.

Clin Vaccine Immunol. 2014 Feb;21(2):174-80. doi: 10.1128/CVI.00662-13. Epub 2013 Dec 11.

PMID:
24334684
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Beneficial role of rapamycin in experimental autoimmune myositis.

Prevel N, Allenbach Y, Klatzmann D, Salomon B, Benveniste O.

PLoS One. 2013 Nov 12;8(11):e74450. doi: 10.1371/journal.pone.0074450. eCollection 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/3eb548ab-c781-4784-9dee-b5a27f7e1643.

PMID:
24265670
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Serum biomarker signature identifies patients with B-cell non-Hodgkin lymphoma associated with cryoglobulinemia vasculitis in chronic HCV infection.

Terrier B, Chaara W, Dufat L, Geri G, Rosenzwajg M, Musset L, Sène D, Saadoun D, Six A, Klatzmann D, Cacoub P.

Autoimmun Rev. 2014 Mar;13(3):319-26. doi: 10.1016/j.autrev.2013.11.001. Epub 2013 Nov 9. Review.

PMID:
24220267
[PubMed - indexed for MEDLINE]
19.

Self-specific memory regulatory T cells protect embryos at implantation in mice.

Chen T, Darrasse-Jèze G, Bergot AS, Courau T, Churlaud G, Valdivia K, Strominger JL, Ruocco MG, Chaouat G, Klatzmann D.

J Immunol. 2013 Sep 1;191(5):2273-81. doi: 10.4049/jimmunol.1202413. Epub 2013 Aug 2.

PMID:
23913969
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Phase I clinical trial combining imatinib mesylate and IL-2: HLA-DR+ NK cell levels correlate with disease outcome.

Chaput N, Flament C, Locher C, Desbois M, Rey A, Rusakiewicz S, Poirier-Colame V, Pautier P, Le Cesne A, Soria JC, Paci A, Rosenzwajg M, Klatzmann D, Eggermont A, Robert C, Zitvogel L.

Oncoimmunology. 2013 Feb 1;2(2):e23080.

PMID:
23525357
[PubMed]
Free PMC Article
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