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Items: 1 to 20 of 158

1.

Deconstructing brain-derived neurotrophic factor actions in adult brain circuits to bridge an existing informational gap in neuro-cell biology.

Bowling H, Bhattacharya A, Klann E, Chao MV.

Neural Regen Res. 2016 Mar;11(3):363-7. doi: 10.4103/1673-5374.179031. Review.

2.

Repression of the eIF2α kinase PERK alleviates mGluR-LTD impairments in a mouse model of Alzheimer's disease.

Yang W, Zhou X, Zimmermann HR, Cavener DR, Klann E, Ma T.

Neurobiol Aging. 2016 May;41:19-24. doi: 10.1016/j.neurobiolaging.2016.02.005. Epub 2016 Feb 13.

PMID:
27103515
3.

Genetically Dissecting Cortical Neurons Involved in Epilepsy in Angelman Syndrome.

Santini E, Klann E.

Neuron. 2016 Apr 6;90(1):1-3. doi: 10.1016/j.neuron.2016.03.023.

PMID:
27054611
4.

Alzheimer's disease: Lost memories found.

Shrestha P, Klann E.

Nature. 2016 Mar 24;531(7595):450-1. doi: 10.1038/nature17312. Epub 2016 Mar 16. No abstract available.

PMID:
26982731
5.

Calmodulin activity regulates group I metabotropic glutamate receptor-mediated signal transduction and synaptic depression.

Sethna F, Zhang M, Kaphzan H, Klann E, Autio D, Cox CL, Wang H.

J Neurosci Res. 2016 May;94(5):401-8. doi: 10.1002/jnr.23719. Epub 2016 Feb 11.

PMID:
26864654
6.

Cc2d1a Loss of Function Disrupts Functional and Morphological Development in Forebrain Neurons Leading to Cognitive and Social Deficits.

Oaks AW, Zamarbide M, Tambunan DE, Santini E, Di Costanzo S, Pond HL, Johnson MW, Lin J, Gonzalez DM, Boehler JF, Wu GK, Klann E, Walsh CA, Manzini MC.

Cereb Cortex. 2016 Jan 29. pii: bhw009. [Epub ahead of print]

PMID:
26826102
7.

Targeting Translation Control with p70 S6 Kinase 1 Inhibitors to Reverse Phenotypes in Fragile X Syndrome Mice.

Bhattacharya A, Mamcarz M, Mullins C, Choudhury A, Boyle RG, Smith DG, Walker DW, Klann E.

Neuropsychopharmacology. 2015 Dec 28. doi: 10.1038/npp.2015.369. [Epub ahead of print]

PMID:
26708105
8.

Mitochondrial Superoxide Contributes to Hippocampal Synaptic Dysfunction and Memory Deficits in Angelman Syndrome Model Mice.

Santini E, Turner KL, Ramaraj AB, Murphy MP, Klann E, Kaphzan H.

J Neurosci. 2015 Dec 9;35(49):16213-20. doi: 10.1523/JNEUROSCI.2246-15.2015.

PMID:
26658871
9.

RCAN1 overexpression promotes age-dependent mitochondrial dysregulation related to neurodegeneration in Alzheimer's disease.

Wong H, Levenga J, Cain P, Rothermel B, Klann E, Hoeffer C.

Acta Neuropathol. 2015 Dec;130(6):829-43. doi: 10.1007/s00401-015-1499-8. Epub 2015 Oct 24.

10.

Dysregulation of Mammalian Target of Rapamycin Signaling in Mouse Models of Autism.

Huber KM, Klann E, Costa-Mattioli M, Zukin RS.

J Neurosci. 2015 Oct 14;35(41):13836-42. doi: 10.1523/JNEUROSCI.2656-15.2015. Review.

11.

Dysregulation and restoration of translational homeostasis in fragile X syndrome.

Richter JD, Bassell GJ, Klann E.

Nat Rev Neurosci. 2015 Oct;16(10):595-605. doi: 10.1038/nrn4001. Epub 2015 Sep 9. Review.

12.

eIF4E/Fmr1 double mutant mice display cognitive impairment in addition to ASD-like behaviors.

Huynh TN, Shah M, Koo SY, Faraud KS, Santini E, Klann E.

Neurobiol Dis. 2015 Nov;83:67-74. doi: 10.1016/j.nbd.2015.08.016. Epub 2015 Aug 22.

PMID:
26306459
13.

BONLAC: A combinatorial proteomic technique to measure stimulus-induced translational profiles in brain slices.

Bowling H, Bhattacharya A, Zhang G, Lebowitz JZ, Alam D, Smith PT, Kirshenbaum K, Neubert TA, Vogel C, Chao MV, Klann E.

Neuropharmacology. 2016 Jan;100:76-89. doi: 10.1016/j.neuropharm.2015.07.017. Epub 2015 Jul 21.

PMID:
26205778
14.

Increased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in fragile X syndrome.

Gross C, Chang CW, Kelly SM, Bhattacharya A, McBride SM, Danielson SW, Jiang MQ, Chan CB, Ye K, Gibson JR, Klann E, Jongens TA, Moberg KH, Huber KM, Bassell GJ.

Cell Rep. 2015 May 5;11(5):727-36. doi: 10.1016/j.celrep.2015.03.060. Epub 2015 Apr 23.

15.

How ketamine helps to overcome depression.

Huynh TN, Klann E.

Elife. 2014 Dec 12;3:e05418. doi: 10.7554/eLife.05418.

16.

Reciprocal signaling between translational control pathways and synaptic proteins in autism spectrum disorders.

Santini E, Klann E.

Sci Signal. 2014 Oct 28;7(349):re10. doi: 10.1126/scisignal.2005832. Review.

PMID:
25351249
17.

In-depth quantitative proteomic analysis of de novo protein synthesis induced by brain-derived neurotrophic factor.

Zhang G, Bowling H, Hom N, Kirshenbaum K, Klann E, Chao MV, Neubert TA.

J Proteome Res. 2014 Dec 5;13(12):5707-14. doi: 10.1021/pr5006982. Epub 2014 Oct 13.

18.

Identification of fragile X syndrome specific molecular markers in human fibroblasts: a useful model to test the efficacy of therapeutic drugs.

Kumari D, Bhattacharya A, Nadel J, Moulton K, Zeak NM, Glicksman A, Dobkin C, Brick DJ, Schwartz PH, Smith CB, Klann E, Usdin K.

Hum Mutat. 2014 Dec;35(12):1485-94. doi: 10.1002/humu.22699.

19.

Shaping dendritic spines in autism spectrum disorder: mTORC1-dependent macroautophagy.

Bowling H, Klann E.

Neuron. 2014 Sep 3;83(5):994-6. doi: 10.1016/j.neuron.2014.08.021.

20.

Inhibition of AMP-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β.

Ma T, Chen Y, Vingtdeux V, Zhao H, Viollet B, Marambaud P, Klann E.

J Neurosci. 2014 Sep 3;34(36):12230-8. doi: 10.1523/JNEUROSCI.1694-14.2014.

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