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Items: 9


Transient in utero nicotine exposure stimulates mechanosensory-dependent lung development.

Gupta S, Hudak J, Killeen E, Larson JE, Cohen JC.

Exp Lung Res. 2010 Oct;36(8):491-8. doi: 10.3109/01902141003690371.


Adult onset lung disease following transient disruption of fetal stretch-induced differentiation.

Hudak JJ, Killeen E, Chandran A, Cohen JC, Larson JE.

Respir Res. 2009 May 6;10:34. doi: 10.1186/1465-9921-10-34.


Transient in utero disruption of cystic fibrosis transmembrane conductance regulator causes phenotypic changes in alveolar type II cells in adult rats.

Gad A, Callender DL, Killeen E, Hudak J, Dlugosz MA, Larson JE, Cohen JC, Chander A.

BMC Cell Biol. 2009 Mar 31;10:24. doi: 10.1186/1471-2121-10-24.


Small interfering peptide (siP) for in vivo examination of the developing lung interactonome.

Cohen JC, Killeen E, Chander A, Takemaru K, Larson JE, Treharne KJ, Mehta A.

Dev Dyn. 2009 Feb;238(2):386-93. doi: 10.1002/dvdy.21834.


CFTR and Wnt/beta-catenin signaling in lung development.

Cohen JC, Larson JE, Killeen E, Love D, Takemaru K.

BMC Dev Biol. 2008 Jul 6;8:70. doi: 10.1186/1471-213X-8-70.


Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals.

Li N, Alam J, Venkatesan MI, Eiguren-Fernandez A, Schmitz D, Di Stefano E, Slaughter N, Killeen E, Wang X, Huang A, Wang M, Miguel AH, Cho A, Sioutas C, Nel AE.

J Immunol. 2004 Sep 1;173(5):3467-81.


Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element.

Balogun E, Hoque M, Gong P, Killeen E, Green CJ, Foresti R, Alam J, Motterlini R.

Biochem J. 2003 May 1;371(Pt 3):887-95.


Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2.

Alam J, Killeen E, Gong P, Naquin R, Hu B, Stewart D, Ingelfinger JR, Nath KA.

Am J Physiol Renal Physiol. 2003 Apr;284(4):F743-52. Epub 2002 Nov 26.


Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium.

Stewart D, Killeen E, Naquin R, Alam S, Alam J.

J Biol Chem. 2003 Jan 24;278(4):2396-402. Epub 2002 Nov 18.

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