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Results: 1 to 20 of 28

1.

The non-random repositioning of whole chromosomes and individual gene loci in interphase nuclei and its relevance in disease, infection, aging, and cancer.

Bridger JM, Arican-Gotkas HD, Foster HA, Godwin LS, Harvey A, Kill IR, Knight M, Mehta IS, Ahmed MH.

Adv Exp Med Biol. 2014;773:263-79. doi: 10.1007/978-1-4899-8032-8_12. Review. Erratum in: Adv Exp Med Biol. 2014;773:E1.

PMID:
24563352
[PubMed - indexed for MEDLINE]
2.

Progeria Research Day at Brunel University.

Bridger JM, Eskiw CH, Makarov EM, Tree D, Kill IR.

Nucleus. 2011 Nov-Dec;2(6):517-22. doi: 10.4161/nucl.2.6.17605. Epub 2011 Nov 1. Review.

PMID:
22064469
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford progeria syndrome cells.

Mehta IS, Eskiw CH, Arican HD, Kill IR, Bridger JM.

Genome Biol. 2011 Aug 12;12(8):R74. doi: 10.1186/gb-2011-12-8-r74.

PMID:
21838864
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Progeria, the nucleolus and farnesyltransferase inhibitors.

Mehta IS, Bridger JM, Kill IR.

Biochem Soc Trans. 2010 Feb;38(Pt 1):287-91. doi: 10.1042/BST0380287.

PMID:
20074076
[PubMed - indexed for MEDLINE]
5.

The in vitro kinetics of senescence of Fischer 344 rat embryo fibroblasts.

Faragher RG, Kill IR.

Biogerontology. 2009 Jun;10(3):285-9. doi: 10.1007/s10522-008-9198-7. Epub 2008 Dec 30.

PMID:
19115081
[PubMed - indexed for MEDLINE]
6.

Towards a Drosophila model of Hutchinson-Gilford progeria syndrome.

Beard GS, Bridger JM, Kill IR, Tree DR.

Biochem Soc Trans. 2008 Dec;36(Pt 6):1389-92. doi: 10.1042/BST0361389.

PMID:
19021561
[PubMed - indexed for MEDLINE]
7.

Nuclear motors and nuclear structures containing A-type lamins and emerin: is there a functional link?

Mehta IS, Elcock LS, Amira M, Kill IR, Bridger JM.

Biochem Soc Trans. 2008 Dec;36(Pt 6):1384-8. doi: 10.1042/BST0361384. Review.

PMID:
19021560
[PubMed - indexed for MEDLINE]
8.

The nuclear lamina. Both a structural framework and a platform for genome organization.

Bridger JM, Foeger N, Kill IR, Herrmann H.

FEBS J. 2007 Mar;274(6):1354-61. Review.

PMID:
17489093
[PubMed - indexed for MEDLINE]
9.

Alterations to nuclear architecture and genome behavior in senescent cells.

Mehta IS, Figgitt M, Clements CS, Kill IR, Bridger JM.

Ann N Y Acad Sci. 2007 Apr;1100:250-63. Review.

PMID:
17460187
[PubMed - indexed for MEDLINE]
10.

Primary laminopathy fibroblasts display altered genome organization and apoptosis.

Meaburn KJ, Cabuy E, Bonne G, Levy N, Morris GE, Novelli G, Kill IR, Bridger JM.

Aging Cell. 2007 Apr;6(2):139-53. Epub 2007 Feb 5.

PMID:
17274801
[PubMed - indexed for MEDLINE]
Free Article
11.

Heterogeneity of dimer excision in young and senescent human dermal fibroblasts.

Boyle J, Kill IR, Parris CN.

Aging Cell. 2005 Oct;4(5):247-55.

PMID:
16164424
[PubMed - indexed for MEDLINE]
12.

Analysis of UV-induced damage and repair in young and senescent human dermal fibroblasts using the comet assay.

Al-Baker EA, Oshin M, Hutchison CJ, Kill IR.

Mech Ageing Dev. 2005 Jun-Jul;126(6-7):664-72. Epub 2005 Jan 26.

PMID:
15888320
[PubMed - indexed for MEDLINE]
13.

Aging of Hutchinson-Gilford progeria syndrome fibroblasts is characterised by hyperproliferation and increased apoptosis.

Bridger JM, Kill IR.

Exp Gerontol. 2004 May;39(5):717-24.

PMID:
15130666
[PubMed - indexed for MEDLINE]
14.

A p53-independent pathway regulates nucleolar segregation and antigen translocation in response to DNA damage induced by UV irradiation.

Al-Baker EA, Boyle J, Harry R, Kill IR.

Exp Cell Res. 2004 Jan 1;292(1):179-86.

PMID:
14720517
[PubMed - indexed for MEDLINE]
15.

Re-modelling of nuclear architecture in quiescent and senescent human fibroblasts.

Bridger JM, Boyle S, Kill IR, Bickmore WA.

Curr Biol. 2000 Feb 10;10(3):149-52.

PMID:
10679329
[PubMed - indexed for MEDLINE]
Free Article
16.

Ageing research in the UK: plenty of proliferative potential. Cellular Senescence: the future of ageing. Oxford, United Kingdom, 16-17 July 1998.

Kill IR.

Mol Med Today. 1998 Nov;4(11):466-7. No abstract available.

PMID:
9857364
[PubMed - indexed for MEDLINE]
17.

Association of pKi-67 with satellite DNA of the human genome in early G1 cells.

Bridger JM, Kill IR, Lichter P.

Chromosome Res. 1998 Jan;6(1):13-24.

PMID:
9510506
[PubMed - indexed for MEDLINE]
18.

The kinetics of senescence in retinal pigmented epithelial cells: a test for the telomere hypothesis of ageing?

Rawes V, Kipling D, Kill IR, Faragher RG.

Biochemistry (Mosc). 1997 Nov;62(11):1291-5.

PMID:
9467853
[PubMed - indexed for MEDLINE]
19.

Cell cycle changes in A-type lamin associations detected in human dermal fibroblasts using monoclonal antibodies.

Dyer JA, Kill IR, Pugh G, Quinlan RA, Lane EB, Hutchison CJ.

Chromosome Res. 1997 Sep;5(6):383-94.

PMID:
9364940
[PubMed - indexed for MEDLINE]
20.

Different kinetics of senescence in human fibroblasts and peritoneal mesothelial cells.

Thomas E, al-Baker E, Dropcova S, Denyer S, Ostad N, Lloyd A, Kill IR, Faragher RG.

Exp Cell Res. 1997 Oct 10;236(1):355-8.

PMID:
9344618
[PubMed - indexed for MEDLINE]

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