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Results: 1 to 20 of 78

1.

Fetal inhibition of inflammation improves disease phenotypes in Harlequin Ichthyosis.

Cottle DL, Ursino GM, Chi Ieng Ip S, Jones L, DiTommaso T, Hacking DF, Mangan NE, Mellett NA, Henley KJ, Sviridov D, Nold-Petry CA, Nold MF, Meikle PJ, Kile BT, Smyth I.

Hum Mol Genet. 2014 Sep 10. pii: ddu459. [Epub ahead of print]

PMID:
25209981
[PubMed - as supplied by publisher]
2.

Effect of thrombopoietin receptor agonists on the apoptotic profile of platelets in patients with chronic immune thrombocytopenia.

Mitchell WB, Pinheiro MP, Boulad N, Kaplan D, Edison MN, Psaila B, Karpoff M, White MJ, Josefsson EC, Kile BT, Bussel JB.

Am J Hematol. 2014 Aug 16. doi: 10.1002/ajh.23832. [Epub ahead of print]

PMID:
25132654
[PubMed - as supplied by publisher]
3.

A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo.

Potts KS, Sargeant TJ, Markham JF, Shi W, Biben C, Josefsson EC, Whitehead LW, Rogers KL, Liakhovitskaia A, Smyth GK, Kile BT, Medvinsky A, Alexander WS, Hilton DJ, Taoudi S.

Blood. 2014 Jul 25. pii: blood-2014-02-559468. [Epub ahead of print]

PMID:
25079356
[PubMed - as supplied by publisher]
4.

Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming.

Allam R, Lawlor KE, Yu EC, Mildenhall AL, Moujalled DM, Lewis RS, Ke F, Mason KD, White MJ, Stacey KJ, Strasser A, O'Reilly LA, Alexander W, Kile BT, Vaux DL, Vince JE.

EMBO Rep. 2014 Sep;15(9):982-90. doi: 10.15252/embr.201438463. Epub 2014 Jul 2.

PMID:
24990442
[PubMed - in process]
5.

CHD7 deficiency in "Looper", a new mouse model of CHARGE syndrome, results in ossicle malformation, otosclerosis and hearing impairment.

Ogier JM, Carpinelli MR, Arhatari BD, Symons RC, Kile BT, Burt RA.

PLoS One. 2014 May 19;9(5):e97559. doi: 10.1371/journal.pone.0097559. eCollection 2014.

PMID:
24840056
[PubMed - in process]
Free PMC Article
6.

Suppressor of cytokine signaling 4 (SOCS4) protects against severe cytokine storm and enhances viral clearance during influenza infection.

Kedzierski L, Linossi EM, Kolesnik TB, Day EB, Bird NL, Kile BT, Belz GT, Metcalf D, Nicola NA, Kedzierska K, Nicholson SE.

PLoS Pathog. 2014 May 8;10(5):e1004134. doi: 10.1371/journal.ppat.1004134. eCollection 2014 May.

PMID:
24809749
[PubMed - in process]
Free PMC Article
7.

A new mouse model of Canavan leukodystrophy displays hearing impairment due to central nervous system dysmyelination.

Carpinelli MR, Voss AK, Manning MG, Perera AA, Cooray AA, Kile BT, Burt RA.

Dis Model Mech. 2014 Jun;7(6):649-57. doi: 10.1242/dmm.014605. Epub 2014 Mar 28.

PMID:
24682784
[PubMed - in process]
Free PMC Article
8.

Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways.

Josefsson EC, Burnett DL, Lebois M, Debrincat MA, White MJ, Henley KJ, Lane RM, Moujalled D, Preston SP, O'Reilly LA, Pellegrini M, Metcalf D, Strasser A, Kile BT.

Nat Commun. 2014 Mar 17;5:3455. doi: 10.1038/ncomms4455.

PMID:
24632563
[PubMed - in process]
9.

NLRP1a expression in Srebp-1a-deficient mice.

Gerlic M, Croker BA, Cengia LH, Moayeri M, Kile BT, Masters SL.

Cell Metab. 2014 Mar 4;19(3):345-6. doi: 10.1016/j.cmet.2014.02.002. No abstract available.

PMID:
24606891
[PubMed - in process]
10.

Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan.

Liu ZJ, Hoffmeister KM, Hu Z, Mager DE, Ait-Oudhia S, Debrincat MA, Pleines I, Josefsson EC, Kile BT, Italiano J Jr, Ramsey H, Grozovsky R, Veng-Pedersen P, Chavda C, Sola-Visner M.

Blood. 2014 May 29;123(22):3381-9. doi: 10.1182/blood-2013-06-508200. Epub 2014 Mar 5.

PMID:
24599546
[PubMed - indexed for MEDLINE]
11.

The role of apoptosis in megakaryocytes and platelets.

Kile BT.

Br J Haematol. 2014 Apr;165(2):217-26. doi: 10.1111/bjh.12757. Epub 2014 Jan 28. Review.

PMID:
24467740
[PubMed - indexed for MEDLINE]
12.

Loss of Bak enhances lymphocytosis but does not ameliorate thrombocytopaenia in BCL-2 transgenic mice.

Vandenberg CJ, Josefsson EC, Campbell KJ, James C, Lawlor KE, Kile BT, Cory S.

Cell Death Differ. 2014 May;21(5):676-84. doi: 10.1038/cdd.2013.201. Epub 2014 Jan 24.

PMID:
24464220
[PubMed - in process]
Free PMC Article
13.

Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically.

Putoczki TL, Thiem S, Loving A, Busuttil RA, Wilson NJ, Ziegler PK, Nguyen PM, Preaudet A, Farid R, Edwards KM, Boglev Y, Luwor RB, Jarnicki A, Horst D, Boussioutas A, Heath JK, Sieber OM, Pleines I, Kile BT, Nash A, Greten FR, McKenzie BS, Ernst M.

Cancer Cell. 2013 Aug 12;24(2):257-71. doi: 10.1016/j.ccr.2013.06.017.

PMID:
23948300
[PubMed - indexed for MEDLINE]
Free Article
14.

ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis.

Fu Y, Mukhamedova N, Ip S, D'Souza W, Henley KJ, DiTommaso T, Kesani R, Ditiatkovski M, Jones L, Lane RM, Jennings G, Smyth IM, Kile BT, Sviridov D.

Cell Metab. 2013 Aug 6;18(2):225-38. doi: 10.1016/j.cmet.2013.07.003.

PMID:
23931754
[PubMed - indexed for MEDLINE]
Free Article
15.

Two ENU-induced alleles of Atp2b2 cause deafness in mice.

Carpinelli MR, Manning MG, Kile BT, Rachel AB.

PLoS One. 2013 Jun 24;8(6):e67479. doi: 10.1371/journal.pone.0067479. Print 2013.

PMID:
23826306
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia.

Tang JZ, Carmichael CL, Shi W, Metcalf D, Ng AP, Hyland CD, Jenkins NA, Copeland NG, Howell VM, Zhao ZJ, Smyth GK, Kile BT, Alexander WS.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6091-6. doi: 10.1073/pnas.1304234110. Epub 2013 Mar 26.

PMID:
23533276
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A model for studying the hemostatic consumption or destruction of platelets.

Dowling MR, Josefsson EC, Henley KJ, Kile BT, Hodgkin PD.

PLoS One. 2013;8(3):e57783. doi: 10.1371/journal.pone.0057783. Epub 2013 Mar 7.

PMID:
23505441
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

MyD88 is a critical regulator of hematopoietic cell-mediated neuroprotection seen after stroke.

Downes CE, Wong CH, Henley KJ, Guio-Aguilar PL, Zhang M, Ates R, Mansell A, Kile BT, Crack PJ.

PLoS One. 2013;8(3):e57948. doi: 10.1371/journal.pone.0057948. Epub 2013 Mar 4.

PMID:
23483951
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

MCMV-mediated inhibition of the pro-apoptotic Bak protein is required for optimal in vivo replication.

Fleming P, Kvansakul M, Voigt V, Kile BT, Kluck RM, Huang DC, Degli-Esposti MA, Andoniou CE.

PLoS Pathog. 2013 Feb;9(2):e1003192. doi: 10.1371/journal.ppat.1003192. Epub 2013 Feb 28.

PMID:
23468630
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Low adhesion receptor levels on circulating platelets in patients with lymphoproliferative diseases before receiving Navitoclax (ABT-263).

Qiao J, Schoenwaelder SM, Mason KD, Tran H, Davis AK, Kaplan ZS, Jackson SP, Kile BT, Andrews RK, Roberts AW, Gardiner EE.

Blood. 2013 Feb 21;121(8):1479-81. doi: 10.1182/blood-2012-12-467415. No abstract available.

PMID:
23429990
[PubMed - indexed for MEDLINE]
Free Article

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