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Results: 1 to 20 of 77

1.

Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin.

Scherr TD, Hanke ML, Huang O, James DB, Horswill AR, Bayles KW, Fey PD, Torres VJ, Kielian T.

MBio. 2015 Aug 25;6(4). pii: e01021-15. doi: 10.1128/mBio.01021-15.

2.

Interleukin-10 production by myeloid-derived suppressor cells contributes to bacterial persistence during Staphylococcus aureus orthopedic biofilm infection.

Heim CE, Vidlak D, Kielian T.

J Leukoc Biol. 2015 Jul 31. pii: jlb.4VMA0315-125RR. [Epub ahead of print]

PMID:
26232453
3.

IL-12 promotes myeloid-derived suppressor cell recruitment and bacterial persistence during Staphylococcus aureus orthopedic implant infection.

Heim CE, Vidlak D, Scherr TD, Hartman CW, Garvin KL, Kielian T.

J Immunol. 2015 Apr 15;194(8):3861-72. doi: 10.4049/jimmunol.1402689. Epub 2015 Mar 11.

PMID:
25762781
4.

Rot is a key regulator of Staphylococcus aureus biofilm formation.

Mootz JM, Benson MA, Heim CE, Crosby HA, Kavanaugh JS, Dunman PM, Kielian T, Torres VJ, Horswill AR.

Mol Microbiol. 2015 Apr;96(2):388-404. doi: 10.1111/mmi.12943. Epub 2015 Feb 26.

PMID:
25612137
5.

Hemichannels in neurodegenerative diseases: is there a link to pathology?

Bosch M, Kielian T.

Front Cell Neurosci. 2014 Aug 20;8:242. doi: 10.3389/fncel.2014.00242. eCollection 2014.

6.

Transformation of human cathelicidin LL-37 into selective, stable, and potent antimicrobial compounds.

Wang G, Hanke ML, Mishra B, Lushnikova T, Heim CE, Chittezham Thomas V, Bayles KW, Kielian T.

ACS Chem Biol. 2014 Sep 19;9(9):1997-2002. doi: 10.1021/cb500475y. Epub 2014 Jul 30.

7.

Neuroinflammation: good, bad, or indifferent?

Kielian T.

J Neurochem. 2014 Jul;130(1):1-3. doi: 10.1111/jnc.12755. Epub 2014 May 24. No abstract available.

8.

Evidence for aberrant astrocyte hemichannel activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL).

Burkovetskaya M, Karpuk N, Xiong J, Bosch M, Boska MD, Takeuchi H, Suzumura A, Kielian T.

PLoS One. 2014 Apr 15;9(4):e95023. doi: 10.1371/journal.pone.0095023. eCollection 2014.

9.

Myeloid-derived suppressor cells contribute to Staphylococcus aureus orthopedic biofilm infection.

Heim CE, Vidlak D, Scherr TD, Kozel JA, Holzapfel M, Muirhead DE, Kielian T.

J Immunol. 2014 Apr 15;192(8):3778-92. doi: 10.4049/jimmunol.1303408. Epub 2014 Mar 19.

10.

Hiding in Plain Sight: Interplay between Staphylococcal Biofilms and Host Immunity.

Scherr TD, Heim CE, Morrison JM, Kielian T.

Front Immunol. 2014 Feb 5;5:37. doi: 10.3389/fimmu.2014.00037. eCollection 2014. Review.

11.

Critical role for the AIM2 inflammasome during acute CNS bacterial infection.

Hanamsagar R, Aldrich A, Kielian T.

J Neurochem. 2014 May;129(4):704-11. doi: 10.1111/jnc.12669. Epub 2014 Feb 19.

12.

Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation.

Snowden JN, Beaver M, Beenken K, Smeltzer M, Horswill AR, Kielian T.

PLoS One. 2013 Dec 30;8(12):e84089. doi: 10.1371/journal.pone.0084089. eCollection 2013.

13.

A mouse model of Staphylococcus catheter-associated biofilm infection.

Heim CE, Hanke ML, Kielian T.

Methods Mol Biol. 2014;1106:183-91. doi: 10.1007/978-1-62703-736-5_17.

PMID:
24222467
14.

Mouse model of post-arthroplasty Staphylococcus epidermidis joint infection.

Scherr TD, Lindgren KE, Schaeffer CR, Hanke ML, Hartman CW, Kielian T.

Methods Mol Biol. 2014;1106:173-81. doi: 10.1007/978-1-62703-736-5_16.

PMID:
24222466
15.

Global transcriptome analysis of Staphylococcus aureus biofilms in response to innate immune cells.

Scherr TD, Roux CM, Hanke ML, Angle A, Dunman PM, Kielian T.

Infect Immun. 2013 Dec;81(12):4363-76. doi: 10.1128/IAI.00819-13. Epub 2013 Sep 16.

16.

Microglia in juvenile neuronal ceroid lipofuscinosis are primed toward a pro-inflammatory phenotype.

Xiong J, Kielian T.

J Neurochem. 2013 Oct;127(2):245-58. doi: 10.1111/jnc.12385. Epub 2013 Aug 22.

PMID:
23919525
17.

Compartmentalization of immune responses during Staphylococcus aureus cranial bone flap infection.

Cheatle J, Aldrich A, Thorell WE, Boska MD, Kielian T.

Am J Pathol. 2013 Aug;183(2):450-8. doi: 10.1016/j.ajpath.2013.04.031. Epub 2013 Jun 7.

18.

Myeloid differentiation factor 88-dependent signaling is critical for acute organic dust-induced airway inflammation in mice.

Bauer C, Kielian T, Wyatt TA, Romberger DJ, West WW, Gleason AM, Poole JA.

Am J Respir Cell Mol Biol. 2013 Jun;48(6):781-9. doi: 10.1165/rcmb.2012-0479OC.

19.

Blue light eliminates community-acquired methicillin-resistant Staphylococcus aureus in infected mouse skin abrasions.

Dai T, Gupta A, Huang YY, Sherwood ME, Murray CK, Vrahas MS, Kielian T, Hamblin MR.

Photomed Laser Surg. 2013 Nov;31(11):531-8. doi: 10.1089/pho.2012.3365. Epub 2013 Feb 13.

20.

Targeting macrophage activation for the prevention and treatment of Staphylococcus aureus biofilm infections.

Hanke ML, Heim CE, Angle A, Sanderson SD, Kielian T.

J Immunol. 2013 Mar 1;190(5):2159-68. doi: 10.4049/jimmunol.1202348. Epub 2013 Jan 30. Erratum in: J Immunol. 2013 Jun 15;190(12):6709-10.

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