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Results: 1 to 20 of 65

1.

Urinary metabolic profiles in early pregnancy are associated with preterm birth and fetal growth restriction in the Rhea mother-child cohort study.

Maitre L, Fthenou E, Athersuch T, Coen M, Toledano MB, Holmes E, Kogevinas M, Chatzi L, Keun HC.

BMC Med. 2014 Jul 11;12:110. doi: 10.1186/1741-7015-12-110.

PMID:
25012562
[PubMed - in process]
Free PMC Article
2.

Metabonomic analysis of water extracts from different angelica roots by ¹H-nuclear magnetic resonance spectroscopy.

Chan PH, Zhang WL, Lau CH, Cheung CY, Keun HC, Tsim KW, Lam H.

Molecules. 2014 Mar 20;19(3):3460-70. doi: 10.3390/molecules19033460.

PMID:
24658570
[PubMed - in process]
Free Article
3.

The human early-life exposome (HELIX): project rationale and design.

Vrijheid M, Slama R, Robinson O, Chatzi L, Coen M, van den Hazel P, Thomsen C, Wright J, Athersuch TJ, Avellana N, Basagaña X, Brochot C, Bucchini L, Bustamante M, Carracedo A, Casas M, Estivill X, Fairley L, van Gent D, Gonzalez JR, Granum B, Gražulevičienė R, Gutzkow KB, Julvez J, Keun HC, Kogevinas M, McEachan RR, Meltzer HM, Sabidó E, Schwarze PE, Siroux V, Sunyer J, Want EJ, Zeman F, Nieuwenhuijsen MJ.

Environ Health Perspect. 2014 Jun;122(6):535-44. doi: 10.1289/ehp.1307204. Epub 2014 Mar 6.

PMID:
24610234
[PubMed - in process]
Free PMC Article
4.

Metabolomic characterization of nipple aspirate fluid by (1)H NMR spectroscopy and GC-MS.

Tredwell GD, Miller JA, Chow HH, Thompson PA, Keun HC.

J Proteome Res. 2014 Feb 7;13(2):883-9. doi: 10.1021/pr400924k. Epub 2014 Jan 7.

PMID:
24364541
[PubMed - in process]
5.

Serum metabolomic pertubations among workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

Saberi Hosnijeh F, Pechlivanis A, Keun HC, Portengen L, Bueno-de-Mesquita HB, Heederik D, Vermeulen R.

Environ Mol Mutagen. 2013 Aug;54(7):558-65. doi: 10.1002/em.21802. Epub 2013 Aug 1.

PMID:
23907991
[PubMed - indexed for MEDLINE]
6.

Evaluation of 1H NMR metabolic profiling using biofluid mixture design.

Athersuch TJ, Malik S, Weljie A, Newton J, Keun HC.

Anal Chem. 2013 Jul 16;85(14):6674-81. doi: 10.1021/ac400449f. Epub 2013 Jun 26.

PMID:
23730812
[PubMed - indexed for MEDLINE]
7.

Metabolomics in toxicology and preclinical research.

Ramirez T, Daneshian M, Kamp H, Bois FY, Clench MR, Coen M, Donley B, Fischer SM, Ekman DR, Fabian E, Guillou C, Heuer J, Hogberg HT, Jungnickel H, Keun HC, Krennrich G, Krupp E, Luch A, Noor F, Peter E, Riefke B, Seymour M, Skinner N, Smirnova L, Verheij E, Wagner S, Hartung T, van Ravenzwaay B, Leist M.

ALTEX. 2013;30(2):209-25.

PMID:
23665807
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A combination of transcriptomics and metabolomics uncovers enhanced bile acid biosynthesis in HepG2 cells expressing CCAAT/enhancer-binding protein β (C/EBPβ), hepatocyte nuclear factor 4α (HNF4α), and constitutive androstane receptor (CAR).

Blazquez M, Carretero A, Ellis JK, Athersuch TJ, Cavill R, Ebbels TM, Keun HC, Castell JV, Lahoz A, Bort R.

J Proteome Res. 2013 Jun 7;12(6):2732-41. doi: 10.1021/pr400085n. Epub 2013 May 15.

PMID:
23641669
[PubMed - indexed for MEDLINE]
9.

Performance in omics analyses of blood samples in long-term storage: opportunities for the exploitation of existing biobanks in environmental health research.

Hebels DG, Georgiadis P, Keun HC, Athersuch TJ, Vineis P, Vermeulen R, Portengen L, Bergdahl IA, Hallmans G, Palli D, Bendinelli B, Krogh V, Tumino R, Sacerdote C, Panico S, Kleinjans JC, de Kok TM, Smith MT, Kyrtopoulos SA; EnviroGenomarkers Project Consortium.

Environ Health Perspect. 2013 Apr;121(4):480-7. doi: 10.1289/ehp.1205657. Epub 2013 Feb 4.

PMID:
23384616
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Development of quantitative structure-metabolism (QSMR) relationships for substituted anilines based on computational chemistry.

Athersuch TJ, Wilson ID, Keun HC, Lindon JC.

Xenobiotica. 2013 Sep;43(9):792-802. doi: 10.3109/00498254.2013.767953. Epub 2013 Feb 6.

PMID:
23384072
[PubMed - indexed for MEDLINE]
11.

1H HR-MAS NMR spectroscopy of tumor-induced local metabolic "field-effects" enables colorectal cancer staging and prognostication.

Jiménez B, Mirnezami R, Kinross J, Cloarec O, Keun HC, Holmes E, Goldin RD, Ziprin P, Darzi A, Nicholson JK.

J Proteome Res. 2013 Feb 1;12(2):959-68. doi: 10.1021/pr3010106. Epub 2013 Jan 16.

PMID:
23240862
[PubMed - indexed for MEDLINE]
12.

Proteomic and metabolomic responses to connexin43 silencing in primary hepatocyte cultures.

Vinken M, Maes M, Cavill R, Valkenborg D, Ellis JK, Decrock E, Leybaert L, Staes A, Gevaert K, Oliveira AG, Menezes GB, Cogliati B, Dagli ML, Ebbels TM, Witters E, Keun HC, Vanhaecke T, Rogiers V.

Arch Toxicol. 2013 May;87(5):883-94. doi: 10.1007/s00204-012-0994-0. Epub 2012 Dec 7.

PMID:
23224291
[PubMed - indexed for MEDLINE]
13.

Metabolic characterization of Leishmania major infection in activated and nonactivated macrophages.

Lamour SD, Choi BS, Keun HC, Müller I, Saric J.

J Proteome Res. 2012 Aug 3;11(8):4211-22. doi: 10.1021/pr3003358. Epub 2012 Jul 12.

PMID:
22724526
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Metabolic profiling detects early effects of environmental and lifestyle exposure to cadmium in a human population.

Ellis JK, Athersuch TJ, Thomas LD, Teichert F, Pérez-Trujillo M, Svendsen C, Spurgeon DJ, Singh R, Järup L, Bundy JG, Keun HC.

BMC Med. 2012 Jun 19;10:61. doi: 10.1186/1741-7015-10-61.

PMID:
22713677
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis.

Stewart JD, Marchan R, Lesjak MS, Lambert J, Hergenroeder R, Ellis JK, Lau CH, Keun HC, Schmitz G, Schiller J, Eibisch M, Hedberg C, Waldmann H, Lausch E, Tanner B, Sehouli J, Sagemueller J, Staude H, Steiner E, Hengstler JG.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8155-60. doi: 10.1073/pnas.1117654109. Epub 2012 May 8.

PMID:
22570503
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Integrated histopathological and urinary metabonomic investigation of the pathogenesis of microcystin-LR toxicosis.

Cantor GH, Beckonert O, Bollard ME, Keun HC, Ebbels TM, Antti H, Wijsman JA, Bible RH, Breau AP, Cockerell GL, Holmes E, Lindon JC, Nicholson JK.

Vet Pathol. 2013 Jan;50(1):159-71. doi: 10.1177/0300985812443839. Epub 2012 May 2.

PMID:
22552484
[PubMed - in process]
Free Article
17.

Biofluid metabonomics using (1)H NMR spectroscopy: the road to biomarker discovery in gastroenterology and hepatology.

Patel NR, McPhail MJ, Shariff MI, Keun HC, Taylor-Robinson SD.

Expert Rev Gastroenterol Hepatol. 2012 Apr;6(2):239-51. doi: 10.1586/egh.12.1. Review.

PMID:
22375528
[PubMed - indexed for MEDLINE]
18.

Chiral metabonomics: 1H NMR-based enantiospecific differentiation of metabolites in human urine via direct cosolvation with β-cyclodextrin.

Pérez-Trujillo M, Lindon JC, Parella T, Keun HC, Nicholson JK, Athersuch TJ.

Anal Chem. 2012 Mar 20;84(6):2868-74. doi: 10.1021/ac203291d. Epub 2012 Feb 29.

PMID:
22320312
[PubMed - indexed for MEDLINE]
19.

Intra- and interlaboratory reproducibility of ultra performance liquid chromatography-time-of-flight mass spectrometry for urinary metabolic profiling.

Benton HP, Want E, Keun HC, Amberg A, Plumb RS, Goldfain-Blanc F, Walther B, Reily MD, Lindon JC, Holmes E, Nicholson JK, Ebbels TM.

Anal Chem. 2012 Mar 6;84(5):2424-32. doi: 10.1021/ac203200x. Epub 2012 Feb 13.

PMID:
22304021
[PubMed - indexed for MEDLINE]
20.

Outdoor and indoor cadmium distributions near an abandoned smelting works and their relations to human exposure.

Spurgeon DJ, Lawlor A, Hooper HL, Wadsworth R, Svendsen C, Thomas LD, Ellis JK, Bundy JG, Keun HC, Jarup L.

Environ Pollut. 2011 Dec;159(12):3425-32. doi: 10.1016/j.envpol.2011.08.028. Epub 2011 Sep 9.

PMID:
21908085
[PubMed - indexed for MEDLINE]

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