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Items: 1 to 20 of 80

1.

"Watching the Detectives" report of the general assembly of the EU project DETECTIVE Brussels, 24-25 November 2015.

Fernando RN, Chaudhari U, Escher SE, Hengstler JG, Hescheler J, Jennings P, Keun HC, Kleinjans JC, Kolde R, Kollipara L, Kopp-Schneider A, Limonciel A, Nemade H, Nguemo F, Peterson H, Prieto P, Rodrigues RM, Sachinidis A, Schäfer C, Sickmann A, Spitkovsky D, Stöber R, van Breda SG, van de Water B, Vivier M, Zahedi RP, Vinken M, Rogiers V.

Arch Toxicol. 2016 Apr 29. [Epub ahead of print]

PMID:
27129694
2.

Child development accounts (CDAs): An asset-building strategy to empower girls in Uganda.

Curley J, Ssewamala FM, Nabunya P, Ilic V, Keun HC.

Int Soc Work. 2016 Jan 1;59(1):18-31. Epub 2014 Mar 17.

3.

Metabonomic analysis of ovarian tumour cyst fluid by proton nuclear magnetic resonance spectroscopy.

Kyriakides M, Rama N, Sidhu J, Gabra H, Keun HC, El-Bahrawy M.

Oncotarget. 2016 Feb 9;7(6):7216-26. doi: 10.18632/oncotarget.6891.

4.

Inadequate fine-tuning of protein synthesis and failure of amino acid homeostasis following inhibition of the ATPase VCP/p97.

Parzych K, Chinn TM, Chen Z, Loaiza S, Porsch F, Valbuena GN, Kleijnen MF, Karadimitris A, Gentleman E, Keun HC, Auner HW.

Cell Death Dis. 2015 Dec 31;6:e2031. doi: 10.1038/cddis.2015.373.

5.

A Systems Oncology Approach Identifies NT5E as a Key Metabolic Regulator in Tumor Cells and Modulator of Platinum Sensitivity.

Nevedomskaya E, Perryman R, Solanki S, Syed N, Mayboroda OA, Keun HC.

J Proteome Res. 2016 Jan 4;15(1):280-90. doi: 10.1021/acs.jproteome.5b00793. Epub 2015 Dec 17.

PMID:
26629888
6.

Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment.

Chaudhari U, Nemade H, Wagh V, Gaspar JA, Ellis JK, Srinivasan SP, Spitkovski D, Nguemo F, Louisse J, Bremer S, Hescheler J, Keun HC, Hengstler JG, Sachinidis A.

Arch Toxicol. 2015 Nov 4. [Epub ahead of print]

PMID:
26537877
7.

Systematic integration of molecular profiles identifies miR-22 as a regulator of lipid and folate metabolism in breast cancer cells.

Koufaris C, Valbuena GN, Pomyen Y, Tredwell GD, Nevedomskaya E, Lau CH, Yang T, Benito A, Ellis JK, Keun HC.

Oncogene. 2015 Oct 19. doi: 10.1038/onc.2015.333. [Epub ahead of print]

PMID:
26477310
8.

convISA: A simple, convoluted method for isotopomer spectral analysis of fatty acids and cholesterol.

Tredwell GD, Keun HC.

Metab Eng. 2015 Nov;32:125-32. doi: 10.1016/j.ymben.2015.09.008. Epub 2015 Oct 9.

PMID:
26432945
9.

Metabolic profiling in human exposome studies.

Athersuch TJ, Keun HC.

Mutagenesis. 2015 Nov;30(6):755-62. doi: 10.1093/mutage/gev060. Epub 2015 Aug 18.

PMID:
26290610
10.

Influence of glutathione-S-transferase (GST) inhibition on lung epithelial cell injury: role of oxidative stress and metabolism.

Fletcher ME, Boshier PR, Wakabayashi K, Keun HC, Smolenski RT, Kirkham PA, Adcock IM, Barton PJ, Takata M, Marczin N.

Am J Physiol Lung Cell Mol Physiol. 2015 Jun 15;308(12):L1274-85. doi: 10.1152/ajplung.00220.2014. Epub 2015 Apr 10.

PMID:
26078397
11.

Metabolomic Analysis Reveals Increased Aerobic Glycolysis and Amino Acid Deficit in a Cellular Model of Amyotrophic Lateral Sclerosis.

Valbuena GN, Rizzardini M, Cimini S, Siskos AP, Bendotti C, Cantoni L, Keun HC.

Mol Neurobiol. 2016 May;53(4):2222-40. doi: 10.1007/s12035-015-9165-7. Epub 2015 May 12.

12.

diXa: a data infrastructure for chemical safety assessment.

Hendrickx DM, Aerts HJ, Caiment F, Clark D, Ebbels TM, Evelo CT, Gmuender H, Hebels DG, Herwig R, Hescheler J, Jennen DG, Jetten MJ, Kanterakis S, Keun HC, Matser V, Overington JP, Pilicheva E, Sarkans U, Segura-Lepe MP, Sotiriadou I, Wittenberger T, Wittwehr C, Zanzi A, Kleinjans JC.

Bioinformatics. 2015 May 1;31(9):1505-7. doi: 10.1093/bioinformatics/btu827. Epub 2014 Dec 12.

13.

Plasma metabolomic profiles of breast cancer patients after short-term limonene intervention.

Miller JA, Pappan K, Thompson PA, Want EJ, Siskos AP, Keun HC, Wulff J, Hu C, Lang JE, Chow HH.

Cancer Prev Res (Phila). 2015 Jan;8(1):86-93. doi: 10.1158/1940-6207.CAPR-14-0100. Epub 2014 Nov 11.

14.

Alterations of choline phospholipid metabolism in endometrial cancer are caused by choline kinase alpha overexpression and a hyperactivated deacylation pathway.

Trousil S, Lee P, Pinato DJ, Ellis JK, Dina R, Aboagye EO, Keun HC, Sharma R.

Cancer Res. 2014 Dec 1;74(23):6867-77. doi: 10.1158/0008-5472.CAN-13-2409. Epub 2014 Sep 29.

15.

Over-representation of correlation analysis (ORCA): a method for identifying associations between variable sets.

Pomyen Y, Segura M, Ebbels TM, Keun HC.

Bioinformatics. 2015 Jan 1;31(1):102-8. doi: 10.1093/bioinformatics/btu589. Epub 2014 Sep 2.

16.

Urinary metabolic profiles in early pregnancy are associated with preterm birth and fetal growth restriction in the Rhea mother-child cohort study.

Maitre L, Fthenou E, Athersuch T, Coen M, Toledano MB, Holmes E, Kogevinas M, Chatzi L, Keun HC.

BMC Med. 2014 Jul 11;12:110. doi: 10.1186/1741-7015-12-110.

17.

Metabonomic analysis of water extracts from different angelica roots by ¹H-nuclear magnetic resonance spectroscopy.

Chan PH, Zhang WL, Lau CH, Cheung CY, Keun HC, Tsim KW, Lam H.

Molecules. 2014 Mar 20;19(3):3460-70. doi: 10.3390/molecules19033460.

18.

The human early-life exposome (HELIX): project rationale and design.

Vrijheid M, Slama R, Robinson O, Chatzi L, Coen M, van den Hazel P, Thomsen C, Wright J, Athersuch TJ, Avellana N, Basagaña X, Brochot C, Bucchini L, Bustamante M, Carracedo A, Casas M, Estivill X, Fairley L, van Gent D, Gonzalez JR, Granum B, Gražulevičienė R, Gutzkow KB, Julvez J, Keun HC, Kogevinas M, McEachan RR, Meltzer HM, Sabidó E, Schwarze PE, Siroux V, Sunyer J, Want EJ, Zeman F, Nieuwenhuijsen MJ.

Environ Health Perspect. 2014 Jun;122(6):535-44. doi: 10.1289/ehp.1307204. Epub 2014 Mar 7.

19.

Metabolomic characterization of nipple aspirate fluid by (1)H NMR spectroscopy and GC-MS.

Tredwell GD, Miller JA, Chow HH, Thompson PA, Keun HC.

J Proteome Res. 2014 Feb 7;13(2):883-9. doi: 10.1021/pr400924k. Epub 2014 Jan 7.

20.

Serum metabolomic pertubations among workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

Saberi Hosnijeh F, Pechlivanis A, Keun HC, Portengen L, Bueno-de-Mesquita HB, Heederik D, Vermeulen R.

Environ Mol Mutagen. 2013 Aug;54(7):558-65. doi: 10.1002/em.21802. Epub 2013 Aug 1.

PMID:
23907991
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