Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 29

1.

The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1.

Cullis J, Meiri D, Sandi MJ, Radulovich N, Kent OA, Medrano M, Mokady D, Normand J, Larose J, Marcotte R, Marshall CB, Ikura M, Ketela T, Moffat J, Neel BG, Gingras AC, Tsao MS, Rottapel R.

Cancer Cell. 2014 Feb 10;25(2):181-95. doi: 10.1016/j.ccr.2014.01.025.

PMID:
24525234
[PubMed - indexed for MEDLINE]
2.

shRNA kinome screen identifies TBK1 as a therapeutic target for HER2+ breast cancer.

Deng T, Liu JC, Chung PE, Uehling D, Aman A, Joseph B, Ketela T, Jiang Z, Schachter NF, Rottapel R, Egan SE, Al-Awar R, Moffat J, Zacksenhaus E.

Cancer Res. 2014 Apr 1;74(7):2119-30. doi: 10.1158/0008-5472.CAN-13-2138. Epub 2014 Jan 31.

PMID:
24487029
[PubMed - indexed for MEDLINE]
3.

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.

Vizeacoumar FJ, Arnold R, Vizeacoumar FS, Chandrashekhar M, Buzina A, Young JT, Kwan JH, Sayad A, Mero P, Lawo S, Tanaka H, Brown KR, Baryshnikova A, Mak AB, Fedyshyn Y, Wang Y, Brito GC, Kasimer D, Makhnevych T, Ketela T, Datti A, Babu M, Emili A, Pelletier L, Wrana J, Wainberg Z, Kim PM, Rottapel R, O'Brien CA, Andrews B, Boone C, Moffat J.

Mol Syst Biol. 2013 Oct 8;9:696. doi: 10.1038/msb.2013.54.

PMID:
24104479
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate.

Findlay GM, Smith MJ, Lanner F, Hsiung MS, Gish GD, Petsalaki E, Cockburn K, Kaneko T, Huang H, Bagshaw RD, Ketela T, Tucholska M, Taylor L, Bowtell DD, Moffat J, Ikura M, Li SS, Sidhu SS, Rossant J, Pawson T.

Cell. 2013 Feb 28;152(5):1008-20. doi: 10.1016/j.cell.2013.01.056.

PMID:
23452850
[PubMed - indexed for MEDLINE]
Free Article
5.

Suppression of cancer progression by MGAT1 shRNA knockdown.

Beheshti Zavareh R, Sukhai MA, Hurren R, Gronda M, Wang X, Simpson CD, Maclean N, Zih F, Ketela T, Swallow CJ, Moffat J, Rose DR, Schachter H, Schimmer AD, Dennis JW.

PLoS One. 2012;7(9):e43721. doi: 10.1371/journal.pone.0043721. Epub 2012 Sep 5.

PMID:
22957033
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Essential gene profiles in breast, pancreatic, and ovarian cancer cells.

Marcotte R, Brown KR, Suarez F, Sayad A, Karamboulas K, Krzyzanowski PM, Sircoulomb F, Medrano M, Fedyshyn Y, Koh JL, van Dyk D, Fedyshyn B, Luhova M, Brito GC, Vizeacoumar FJ, Vizeacoumar FS, Datti A, Kasimer D, Buzina A, Mero P, Misquitta C, Normand J, Haider M, Ketela T, Wrana JL, Rottapel R, Neel BG, Moffat J.

Cancer Discov. 2012 Feb;2(2):172-89. doi: 10.1158/2159-8290.CD-11-0224. Epub 2011 Dec 29.

PMID:
22585861
[PubMed - indexed for MEDLINE]
7.

A genome wide shRNA screen identifies α/β hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance.

Simpson CD, Hurren R, Kasimer D, MacLean N, Eberhard Y, Ketela T, Moffat J, Schimmer AD.

Apoptosis. 2012 Jul;17(7):666-78. doi: 10.1007/s10495-012-0723-4.

PMID:
22488300
[PubMed - indexed for MEDLINE]
8.

Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation.

Rajan S, Chu Pham Dang H, Djambazian H, Zuzan H, Fedyshyn Y, Ketela T, Moffat J, Hudson TJ, Sladek R.

Physiol Genomics. 2012 Feb 1;44(2):183-97. doi: 10.1152/physiolgenomics.00093.2011. Epub 2011 Dec 6.

PMID:
22147266
[PubMed - indexed for MEDLINE]
Free Article
9.

COLT-Cancer: functional genetic screening resource for essential genes in human cancer cell lines.

Koh JL, Brown KR, Sayad A, Kasimer D, Ketela T, Moffat J.

Nucleic Acids Res. 2012 Jan;40(Database issue):D957-63. doi: 10.1093/nar/gkr959. Epub 2011 Nov 18.

PMID:
22102578
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.

Skrtić M, Sriskanthadevan S, Jhas B, Gebbia M, Wang X, Wang Z, Hurren R, Jitkova Y, Gronda M, Maclean N, Lai CK, Eberhard Y, Bartoszko J, Spagnuolo P, Rutledge AC, Datti A, Ketela T, Moffat J, Robinson BH, Cameron JH, Wrana J, Eaves CJ, Minden MD, Wang JC, Dick JE, Humphries K, Nislow C, Giaever G, Schimmer AD.

Cancer Cell. 2011 Nov 15;20(5):674-88. doi: 10.1016/j.ccr.2011.10.015.

PMID:
22094260
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

CD133 protein N-glycosylation processing contributes to cell surface recognition of the primitive cell marker AC133 epitope.

Mak AB, Blakely KM, Williams RA, Penttilä PA, Shukalyuk AI, Osman KT, Kasimer D, Ketela T, Moffat J.

J Biol Chem. 2011 Nov 25;286(47):41046-56. doi: 10.1074/jbc.M111.261545. Epub 2011 Sep 21.

PMID:
21937449
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Pooled lentiviral shRNA screening for functional genomics in mammalian cells.

Blakely K, Ketela T, Moffat J.

Methods Mol Biol. 2011;781:161-82. doi: 10.1007/978-1-61779-276-2_9.

PMID:
21877282
[PubMed - indexed for MEDLINE]
13.

A comprehensive platform for highly multiplexed mammalian functional genetic screens.

Ketela T, Heisler LE, Brown KR, Ammar R, Kasimer D, Surendra A, Ericson E, Blakely K, Karamboulas D, Smith AM, Durbic T, Arnoldo A, Cheung-Ong K, Koh JL, Gopal S, Cowley GS, Yang X, Grenier JK, Giaever G, Root DE, Moffat J, Nislow C.

BMC Genomics. 2011 May 6;12:213. doi: 10.1186/1471-2164-12-213.

PMID:
21548937
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Inhibition of SREBP1 sensitizes cells to death ligands.

Eberhard Y, Gronda M, Hurren R, Datti A, MacLean N, Ketela T, Moffat J, Wrana JL, Schimmer AD.

Oncotarget. 2011 Mar;2(3):186-96.

PMID:
21406729
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

SATB2 augments ΔNp63α in head and neck squamous cell carcinoma.

Chung J, Lau J, Cheng LS, Grant RI, Robinson F, Ketela T, Reis PP, Roche O, Kamel-Reid S, Moffat J, Ohh M, Perez-Ordonez B, Kaplan DR, Irwin MS.

EMBO Rep. 2010 Oct;11(10):777-83. doi: 10.1038/embor.2010.125. Epub 2010 Sep 10.

PMID:
20829881
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma.

Xu GW, Ali M, Wood TE, Wong D, Maclean N, Wang X, Gronda M, Skrtic M, Li X, Hurren R, Mao X, Venkatesan M, Beheshti Zavareh R, Ketela T, Reed JC, Rose D, Moffat J, Batey RA, Dhe-Paganon S, Schimmer AD.

Blood. 2010 Mar 18;115(11):2251-9. doi: 10.1182/blood-2009-07-231191. Epub 2010 Jan 14.

PMID:
20075161
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Selective inhibition of histone deacetylases sensitizes malignant cells to death receptor ligands.

Wood TE, Dalili S, Simpson CD, Sukhai MA, Hurren R, Anyiwe K, Mao X, Suarez Saiz F, Gronda M, Eberhard Y, MacLean N, Ketela T, Reed JC, Moffat J, Minden MD, Batey RA, Schimmer AD.

Mol Cancer Ther. 2010 Jan;9(1):246-56. doi: 10.1158/1535-7163.MCT-09-0495. Epub 2010 Jan 6.

PMID:
20053768
[PubMed - indexed for MEDLINE]
Free Article
18.

Systematic validation and atomic force microscopy of non-covalent short oligonucleotide barcode microarrays.

Cook MA, Chan CK, Jorgensen P, Ketela T, So D, Tyers M, Ho CY.

PLoS One. 2008 Feb 6;3(2):e1546. doi: 10.1371/journal.pone.0001546.

PMID:
18253494
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans.

Xu D, Jiang B, Ketela T, Lemieux S, Veillette K, Martel N, Davison J, Sillaots S, Trosok S, Bachewich C, Bussey H, Youngman P, Roemer T.

PLoS Pathog. 2007 Jun;3(6):e92.

PMID:
17604452
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast.

Parsons AB, Lopez A, Givoni IE, Williams DE, Gray CA, Porter J, Chua G, Sopko R, Brost RL, Ho CH, Wang J, Ketela T, Brenner C, Brill JA, Fernandez GE, Lorenz TC, Payne GS, Ishihara S, Ohya Y, Andrews B, Hughes TR, Frey BJ, Graham TR, Andersen RJ, Boone C.

Cell. 2006 Aug 11;126(3):611-25.

PMID:
16901791
[PubMed - indexed for MEDLINE]
Free Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Loading ...
Write to the Help Desk