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Results: 1 to 20 of 33

1.

Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells.

Tosti E, Katakowski JA, Schaetzlein S, Kim HS, Ryan CJ, Shales M, Roguev A, Krogan NJ, Palliser D, Keogh MC, Edelmann W.

Genome Med. 2014 Sep 17;6(9):68. doi: 10.1186/s13073-014-0068-4. eCollection 2014.

2.

Drosophila TAP/p32 is a core histone chaperone that cooperates with NAP-1, NLP, and nucleophosmin in sperm chromatin remodeling during fertilization.

Emelyanov AV, Rabbani J, Mehta M, Vershilova E, Keogh MC, Fyodorov DV.

Genes Dev. 2014 Sep 15;28(18):2027-40. doi: 10.1101/gad.248583.114.

3.

Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function.

Kim HS, Mukhopadhyay R, Rothbart SB, Silva AC, Vanoosthuyse V, Radovani E, Kislinger T, Roguev A, Ryan CJ, Xu J, Jahari H, Hardwick KG, Greenblatt JF, Krogan NJ, Fillingham JS, Strahl BD, Bouhassira EE, Edelmann W, Keogh MC.

Cell Rep. 2014 Mar 13;6(5):892-905. doi: 10.1016/j.celrep.2014.01.029. Epub 2014 Feb 22.

4.

The carboxyl terminus of Rtt109 functions in chaperone control of histone acetylation.

Radovani E, Cadorin M, Shams T, El-Rass S, Karsou AR, Kim HS, Kurat CF, Keogh MC, Greenblatt JF, Fillingham JS.

Eukaryot Cell. 2013 May;12(5):654-64. doi: 10.1128/EC.00291-12. Epub 2013 Mar 1.

5.

Poly-acetylated chromatin signatures are preferred epitopes for site-specific histone H4 acetyl antibodies.

Rothbart SB, Lin S, Britton LM, Krajewski K, Keogh MC, Garcia BA, Strahl BD.

Sci Rep. 2012;2:489. doi: 10.1038/srep00489. Epub 2012 Jul 3.

6.

Hierarchical modularity and the evolution of genetic interactomes across species.

Ryan CJ, Roguev A, Patrick K, Xu J, Jahari H, Tong Z, Beltrao P, Shales M, Qu H, Collins SR, Kliegman JI, Jiang L, Kuo D, Tosti E, Kim HS, Edelmann W, Keogh MC, Greene D, Tang C, Cunningham P, Shokat KM, Cagney G, Svensson JP, Guthrie C, Espenshade PJ, Ideker T, Krogan NJ.

Mol Cell. 2012 Jun 8;46(5):691-704. doi: 10.1016/j.molcel.2012.05.028.

7.

The replication-independent histone H3-H4 chaperones HIR, ASF1, and RTT106 co-operate to maintain promoter fidelity.

Silva AC, Xu X, Kim HS, Fillingham J, Kislinger T, Mennella TA, Keogh MC.

J Biol Chem. 2012 Jan 13;287(3):1709-18. doi: 10.1074/jbc.M111.316489. Epub 2011 Nov 29.

8.

Rewiring of genetic networks in response to DNA damage.

Bandyopadhyay S, Mehta M, Kuo D, Sung MK, Chuang R, Jaehnig EJ, Bodenmiller B, Licon K, Copeland W, Shales M, Fiedler D, Dutkowski J, Guénolé A, van Attikum H, Shokat KM, Kolodner RD, Huh WK, Aebersold R, Keogh MC, Krogan NJ, Ideker T.

Science. 2010 Dec 3;330(6009):1385-9. doi: 10.1126/science.1195618. Erratum in: Science. 2011 Jan 21;331(6015):284.

9.

Individual lysine acetylations on the N terminus of Saccharomyces cerevisiae H2A.Z are highly but not differentially regulated.

Mehta M, Braberg H, Wang S, Lozsa A, Shales M, Solache A, Krogan NJ, Keogh MC.

J Biol Chem. 2010 Dec 17;285(51):39855-65. doi: 10.1074/jbc.M110.185967. Epub 2010 Oct 14.

10.

Sometimes one just isn't enough: do vertebrates contain an H2A.Z hyper-variant?

Mehta M, Kim HS, Keogh MC.

J Biol. 2010;9(1):3. doi: 10.1186/jbiol214. Epub 2010 Jan 21.

11.

An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe.

Kim HS, Vanoosthuyse V, Fillingham J, Roguev A, Watt S, Kislinger T, Treyer A, Carpenter LR, Bennett CS, Emili A, Greenblatt JF, Hardwick KG, Krogan NJ, Bähler J, Keogh MC.

Nat Struct Mol Biol. 2009 Dec;16(12):1286-93. doi: 10.1038/nsmb.1688. Epub 2009 Nov 15.

12.

Functional organization of the S. cerevisiae phosphorylation network.

Fiedler D, Braberg H, Mehta M, Chechik G, Cagney G, Mukherjee P, Silva AC, Shales M, Collins SR, van Wageningen S, Kemmeren P, Holstege FC, Weissman JS, Keogh MC, Koller D, Shokat KM, Krogan NJ.

Cell. 2009 Mar 6;136(5):952-63. doi: 10.1016/j.cell.2008.12.039.

13.

Ctk1 promotes dissociation of basal transcription factors from elongating RNA polymerase II.

Ahn SH, Keogh MC, Buratowski S.

EMBO J. 2009 Feb 4;28(3):205-12. doi: 10.1038/emboj.2008.280. Epub 2009 Jan 8.

14.

Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109.

Fillingham J, Recht J, Silva AC, Suter B, Emili A, Stagljar I, Krogan NJ, Allis CD, Keogh MC, Greenblatt JF.

Mol Cell Biol. 2008 Jul;28(13):4342-53. doi: 10.1128/MCB.00182-08. Epub 2008 May 5.

15.

GammaH2AX and its role in DNA double-strand break repair.

Fillingham J, Keogh MC, Krogan NJ.

Biochem Cell Biol. 2006 Aug;84(4):568-77. Review.

PMID:
16936829
16.

The Saccharomyces cerevisiae histone H2A variant Htz1 is acetylated by NuA4.

Keogh MC, Mennella TA, Sawa C, Berthelet S, Krogan NJ, Wolek A, Podolny V, Carpenter LR, Greenblatt JF, Baetz K, Buratowski S.

Genes Dev. 2006 Mar 15;20(6):660-5.

17.

gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair.

Chowdhury D, Keogh MC, Ishii H, Peterson CL, Buratowski S, Lieberman J.

Mol Cell. 2005 Dec 9;20(5):801-9. Epub 2005 Nov 28.

18.

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery.

Keogh MC, Kim JA, Downey M, Fillingham J, Chowdhury D, Harrison JC, Onishi M, Datta N, Galicia S, Emili A, Lieberman J, Shen X, Buratowski S, Haber JE, Durocher D, Greenblatt JF, Krogan NJ.

Nature. 2006 Jan 26;439(7075):497-501. Epub 2005 Nov 20.

PMID:
16299494
19.

Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

Keogh MC, Kurdistani SK, Morris SA, Ahn SH, Podolny V, Collins SR, Schuldiner M, Chin K, Punna T, Thompson NJ, Boone C, Emili A, Weissman JS, Hughes TR, Strahl BD, Grunstein M, Greenblatt JF, Buratowski S, Krogan NJ.

Cell. 2005 Nov 18;123(4):593-605.

20.

BRCA1/BARD1 ubiquitinate phosphorylated RNA polymerase II.

Starita LM, Horwitz AA, Keogh MC, Ishioka C, Parvin JD, Chiba N.

J Biol Chem. 2005 Jul 1;280(26):24498-505. Epub 2005 May 10.

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