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Results: 1 to 20 of 59

1.

Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach.

Lai L, Leone TC, Keller MP, Martin OJ, Broman AT, Nigro J, Kapoor K, Koves TR, Stevens R, Ilkayeva OR, Vega RB, Attie AD, Muoio DM, Kelly DP.

Circ Heart Fail. 2014 Nov;7(6):1022-31. doi: 10.1161/CIRCHEARTFAILURE.114.001469. Epub 2014 Sep 18.

PMID:
25236884
[PubMed - in process]
2.

RNA-Seq alignment to individualized genomes improves transcript abundance estimates in multiparent populations.

Munger SC, Raghupathy N, Choi K, Simons AK, Gatti DM, Hinerfeld DA, Svenson KL, Keller MP, Attie AD, Hibbs MA, Graber JH, Chesler EJ, Churchill GA.

Genetics. 2014 Sep;198(1):59-73. doi: 10.1534/genetics.114.165886.

PMID:
25236449
[PubMed - in process]
Free PMC Article
3.

A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo.

Johnson LM, Barrick S, Hager MV, McFedries A, Homan EA, Rabaglia ME, Keller MP, Attie AD, Saghatelian A, Bisello A, Gellman SH.

J Am Chem Soc. 2014 Sep 17;136(37):12848-51. doi: 10.1021/ja507168t. Epub 2014 Sep 5.

PMID:
25191938
[PubMed - in process]
4.

SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed β cells.

Kebede MA, Oler AT, Gregg T, Balloon AJ, Johnson A, Mitok K, Rabaglia M, Schueler K, Stapleton D, Thorstenson C, Wrighton L, Floyd BJ, Richards O, Raines S, Eliceiri K, Seidah NG, Rhodes C, Keller MP, Coon JL, Audhya A, Attie AD.

J Clin Invest. 2014 Oct 1;124(10):4240-56. doi: 10.1172/JCI74072. Epub 2014 Aug 26.

PMID:
25157818
[PubMed - in process]
5.

Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion.

Bhatnagar S, Soni MS, Wrighton LS, Hebert AS, Zhou AS, Paul PK, Gregg T, Rabaglia ME, Keller MP, Coon JJ, Attie AD.

J Biol Chem. 2014 Sep 5;289(36):25276-86. doi: 10.1074/jbc.M114.575985. Epub 2014 Jul 7.

PMID:
25002582
[PubMed - in process]
6.

Downregulation of carnitine acyl-carnitine translocase by miRNAs 132 and 212 amplifies glucose-stimulated insulin secretion.

Soni MS, Rabaglia ME, Bhatnagar S, Shang J, Ilkayeva O, Mynatt R, Zhou YP, Schadt EE, Thornberry NA, Muoio DM, Keller MP, Attie AD.

Diabetes. 2014 Nov;63(11):3805-14. doi: 10.2337/db13-1677. Epub 2014 Jun 26.

PMID:
24969106
[PubMed - in process]
7.

A role for peroxisome proliferator-activated receptor γ coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growth.

Martin OJ, Lai L, Soundarapandian MM, Leone TC, Zorzano A, Keller MP, Attie AD, Muoio DM, Kelly DP.

Circ Res. 2014 Feb 14;114(4):626-36. doi: 10.1161/CIRCRESAHA.114.302562. Epub 2013 Dec 23.

PMID:
24366168
[PubMed - indexed for MEDLINE]
8.

Neutron-encoded protein quantification by peptide carbamylation.

Ulbrich A, Merrill AE, Hebert AS, Westphall MS, Keller MP, Attie AD, Coon JJ.

J Am Soc Mass Spectrom. 2014 Jan;25(1):6-9. doi: 10.1007/s13361-013-0765-z. Epub 2013 Oct 29.

PMID:
24178922
[PubMed - indexed for MEDLINE]
9.

Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.

Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.

J Biol Chem. 2013 Sep 6;288(36):26209-19. doi: 10.1074/jbc.M113.483396. Epub 2013 Jul 17.

PMID:
23864654
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion.

Kimple ME, Keller MP, Rabaglia MR, Pasker RL, Neuman JC, Truchan NA, Brar HK, Attie AD.

Diabetes. 2013 Jun;62(6):1904-12. doi: 10.2337/db12-0769. Epub 2013 Jan 24.

PMID:
23349487
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Modeling causality for pairs of phenotypes in system genetics.

Neto EC, Broman AT, Keller MP, Attie AD, Zhang B, Zhu J, Yandell BS.

Genetics. 2013 Mar;193(3):1003-13. doi: 10.1534/genetics.112.147124. Epub 2013 Jan 3.

PMID:
23288936
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Integrative analysis of a cross-loci regulation network identifies App as a gene regulating insulin secretion from pancreatic islets.

Tu Z, Keller MP, Zhang C, Rabaglia ME, Greenawalt DM, Yang X, Wang IM, Dai H, Bruss MD, Lum PY, Zhou YP, Kemp DM, Kendziorski C, Yandell BS, Attie AD, Schadt EE, Zhu J.

PLoS Genet. 2012;8(12):e1003107. doi: 10.1371/journal.pgen.1003107. Epub 2012 Dec 6.

PMID:
23236292
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis.

Grimsrud PA, Carson JJ, Hebert AS, Hubler SL, Niemi NM, Bailey DJ, Jochem A, Stapleton DS, Keller MP, Westphall MS, Yandell BS, Attie AD, Coon JJ, Pagliarini DJ.

Cell Metab. 2012 Nov 7;16(5):672-83. doi: 10.1016/j.cmet.2012.10.004.

PMID:
23140645
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Quantile-based permutation thresholds for quantitative trait loci hotspots.

Neto EC, Keller MP, Broman AF, Attie AD, Jansen RC, Broman KW, Yandell BS.

Genetics. 2012 Aug;191(4):1355-65. doi: 10.1534/genetics.112.139451. Epub 2012 Jun 1.

PMID:
22661325
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Tsc2, a positional candidate gene underlying a quantitative trait locus for hepatic steatosis.

Wang CY, Stapleton DS, Schueler KL, Rabaglia ME, Oler AT, Keller MP, Kendziorski CM, Broman KW, Yandell BS, Schadt EE, Attie AD.

J Lipid Res. 2012 Aug;53(8):1493-501. doi: 10.1194/jlr.M025239. Epub 2012 May 23.

PMID:
22628617
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion.

Bhatnagar S, Oler AT, Rabaglia ME, Stapleton DS, Schueler KL, Truchan NA, Worzella SL, Stoehr JP, Clee SM, Yandell BS, Keller MP, Thurmond DC, Attie AD.

PLoS Genet. 2011 Oct;7(10):e1002323. doi: 10.1371/journal.pgen.1002323. Epub 2011 Oct 6.

PMID:
21998599
[PubMed - indexed for MEDLINE]
Free PMC Article
17.
18.

A model selection approach for expression quantitative trait loci (eQTL) mapping.

Wang P, Dawson JA, Keller MP, Yandell BS, Thornberry NA, Zhang BB, Wang IM, Schadt EE, Attie AD, Kendziorski C.

Genetics. 2011 Feb;187(2):611-21. doi: 10.1534/genetics.110.122796. Epub 2010 Nov 29.

PMID:
21115971
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Gene co-expression modules and type 2 diabetes.

Attie AD, Keller MP.

Results Probl Cell Differ. 2010;52:47-56. doi: 10.1007/978-3-642-14426-4_5. Review.

PMID:
20865371
[PubMed - indexed for MEDLINE]
20.

Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation.

Babak T, Garrett-Engele P, Armour CD, Raymond CK, Keller MP, Chen R, Rohl CA, Johnson JM, Attie AD, Fraser HB, Schadt EE.

BMC Genomics. 2010 Aug 13;11:473. doi: 10.1186/1471-2164-11-473.

PMID:
20707912
[PubMed - indexed for MEDLINE]
Free PMC Article

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