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Results: 1 to 20 of 55

1.

Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion.

Bhatnagar S, Soni MS, Wrighton LS, Hebert AS, Zhou AS, Paul PK, Gregg T, Rabaglia ME, Keller MP, Coon JJ, Attie AD.

J Biol Chem. 2014 Jul 7. pii: jbc.M114.575985. [Epub ahead of print]

PMID:
25002582
[PubMed - as supplied by publisher]
Free Article
2.

Downregulation of Carnitine acyl-carnitine translocase by miRNAs 132 and 212 amplifies glucose-stimulated insulin secretion.

Soni MS, Rabaglia ME, Bhatnagar S, Shang J, Ilkayeva O, Mynatt R, Zhou YP, Schadt EE, Thornberry NA, Muoio DM, Keller MP, Attie AD.

Diabetes. 2014 Jun 26. pii: DB_131677. [Epub ahead of print]

PMID:
24969106
[PubMed - as supplied by publisher]
3.

A role for peroxisome proliferator-activated receptor γ coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growth.

Martin OJ, Lai L, Soundarapandian MM, Leone TC, Zorzano A, Keller MP, Attie AD, Muoio DM, Kelly DP.

Circ Res. 2014 Feb 14;114(4):626-36. doi: 10.1161/CIRCRESAHA.114.302562. Epub 2013 Dec 23.

PMID:
24366168
[PubMed - indexed for MEDLINE]
4.

Neutron-encoded protein quantification by peptide carbamylation.

Ulbrich A, Merrill AE, Hebert AS, Westphall MS, Keller MP, Attie AD, Coon JJ.

J Am Soc Mass Spectrom. 2014 Jan;25(1):6-9. doi: 10.1007/s13361-013-0765-z. Epub 2013 Oct 29.

PMID:
24178922
[PubMed - in process]
5.

Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.

Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.

J Biol Chem. 2013 Sep 6;288(36):26209-19. doi: 10.1074/jbc.M113.483396. Epub 2013 Jul 17.

PMID:
23864654
[PubMed - indexed for MEDLINE]
6.

Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion.

Kimple ME, Keller MP, Rabaglia MR, Pasker RL, Neuman JC, Truchan NA, Brar HK, Attie AD.

Diabetes. 2013 Jun;62(6):1904-12. doi: 10.2337/db12-0769. Epub 2013 Jan 24.

PMID:
23349487
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Modeling causality for pairs of phenotypes in system genetics.

Neto EC, Broman AT, Keller MP, Attie AD, Zhang B, Zhu J, Yandell BS.

Genetics. 2013 Mar;193(3):1003-13. doi: 10.1534/genetics.112.147124. Epub 2013 Jan 3.

PMID:
23288936
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Integrative analysis of a cross-loci regulation network identifies App as a gene regulating insulin secretion from pancreatic islets.

Tu Z, Keller MP, Zhang C, Rabaglia ME, Greenawalt DM, Yang X, Wang IM, Dai H, Bruss MD, Lum PY, Zhou YP, Kemp DM, Kendziorski C, Yandell BS, Attie AD, Schadt EE, Zhu J.

PLoS Genet. 2012;8(12):e1003107. doi: 10.1371/journal.pgen.1003107. Epub 2012 Dec 6.

PMID:
23236292
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis.

Grimsrud PA, Carson JJ, Hebert AS, Hubler SL, Niemi NM, Bailey DJ, Jochem A, Stapleton DS, Keller MP, Westphall MS, Yandell BS, Attie AD, Coon JJ, Pagliarini DJ.

Cell Metab. 2012 Nov 7;16(5):672-83. doi: 10.1016/j.cmet.2012.10.004.

PMID:
23140645
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Quantile-based permutation thresholds for quantitative trait loci hotspots.

Neto EC, Keller MP, Broman AF, Attie AD, Jansen RC, Broman KW, Yandell BS.

Genetics. 2012 Aug;191(4):1355-65. doi: 10.1534/genetics.112.139451. Epub 2012 Jun 1.

PMID:
22661325
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Tsc2, a positional candidate gene underlying a quantitative trait locus for hepatic steatosis.

Wang CY, Stapleton DS, Schueler KL, Rabaglia ME, Oler AT, Keller MP, Kendziorski CM, Broman KW, Yandell BS, Schadt EE, Attie AD.

J Lipid Res. 2012 Aug;53(8):1493-501. doi: 10.1194/jlr.M025239. Epub 2012 May 23.

PMID:
22628617
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion.

Bhatnagar S, Oler AT, Rabaglia ME, Stapleton DS, Schueler KL, Truchan NA, Worzella SL, Stoehr JP, Clee SM, Yandell BS, Keller MP, Thurmond DC, Attie AD.

PLoS Genet. 2011 Oct;7(10):e1002323. doi: 10.1371/journal.pgen.1002323. Epub 2011 Oct 6.

PMID:
21998599
[PubMed - indexed for MEDLINE]
Free PMC Article
13.
14.

A model selection approach for expression quantitative trait loci (eQTL) mapping.

Wang P, Dawson JA, Keller MP, Yandell BS, Thornberry NA, Zhang BB, Wang IM, Schadt EE, Attie AD, Kendziorski C.

Genetics. 2011 Feb;187(2):611-21. doi: 10.1534/genetics.110.122796. Epub 2010 Nov 29.

PMID:
21115971
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Gene co-expression modules and type 2 diabetes.

Attie AD, Keller MP.

Results Probl Cell Differ. 2010;52:47-56. doi: 10.1007/978-3-642-14426-4_5. Review.

PMID:
20865371
[PubMed - indexed for MEDLINE]
16.

Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation.

Babak T, Garrett-Engele P, Armour CD, Raymond CK, Keller MP, Chen R, Rohl CA, Johnson JM, Attie AD, Fraser HB, Schadt EE.

BMC Genomics. 2010 Aug 13;11:473. doi: 10.1186/1471-2164-11-473.

PMID:
20707912
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation.

Davis DB, Lavine JA, Suhonen JI, Krautkramer KA, Rabaglia ME, Sperger JM, Fernandez LA, Yandell BS, Keller MP, Wang IM, Schadt EE, Attie AD.

Mol Endocrinol. 2010 Sep;24(9):1822-34. doi: 10.1210/me.2010-0082. Epub 2010 Jul 21.

PMID:
20660304
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

BTBR Ob/Ob mutant mice model progressive diabetic nephropathy.

Hudkins KL, Pichaiwong W, Wietecha T, Kowalewska J, Banas MC, Spencer MW, Mühlfeld A, Koelling M, Pippin JW, Shankland SJ, Askari B, Rabaglia ME, Keller MP, Attie AD, Alpers CE.

J Am Soc Nephrol. 2010 Sep;21(9):1533-42. doi: 10.1681/ASN.2009121290. Epub 2010 Jul 15.

PMID:
20634301
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival.

Lavine JA, Raess PW, Stapleton DS, Rabaglia ME, Suhonen JI, Schueler KL, Koltes JE, Dawson JA, Yandell BS, Samuelson LC, Beinfeld MC, Davis DB, Hellerstein MK, Keller MP, Attie AD.

Endocrinology. 2010 Aug;151(8):3577-88. doi: 10.1210/en.2010-0233. Epub 2010 Jun 9.

PMID:
20534724
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes.

Zhong H, Beaulaurier J, Lum PY, Molony C, Yang X, Macneil DJ, Weingarth DT, Zhang B, Greenawalt D, Dobrin R, Hao K, Woo S, Fabre-Suver C, Qian S, Tota MR, Keller MP, Kendziorski CM, Yandell BS, Castro V, Attie AD, Kaplan LM, Schadt EE.

PLoS Genet. 2010 May 6;6(5):e1000932. doi: 10.1371/journal.pgen.1000932.

PMID:
20463879
[PubMed - indexed for MEDLINE]
Free PMC Article

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