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Results: 1 to 20 of 68

1.

Real-time imaging of DNA damage in yeast cells using ultra-short near-infrared pulsed laser irradiation.

Guarino E, Cojoc G, García-Ulloa A, Tolić IM, Kearsey SE.

PLoS One. 2014 Nov 19;9(11):e113325. doi: 10.1371/journal.pone.0113325. eCollection 2014.

PMID:
25409521
[PubMed - in process]
Free PMC Article
2.

Cellular regulation of ribonucleotide reductase in eukaryotes.

Guarino E, Salguero I, Kearsey SE.

Semin Cell Dev Biol. 2014 Jun;30:97-103. doi: 10.1016/j.semcdb.2014.03.030. Epub 2014 Apr 2. Review.

PMID:
24704278
[PubMed - indexed for MEDLINE]
3.

DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer.

Church DN, Briggs SE, Palles C, Domingo E, Kearsey SJ, Grimes JM, Gorman M, Martin L, Howarth KM, Hodgson SV; NSECG Collaborators, Kaur K, Taylor J, Tomlinson IP.

Hum Mol Genet. 2013 Jul 15;22(14):2820-8. doi: 10.1093/hmg/ddt131. Epub 2013 Mar 24.

PMID:
23528559
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Sequential steps in DNA replication are inhibited to ensure reduction of ploidy in meiosis.

Hua H, Namdar M, Ganier O, Gregan J, Méchali M, Kearsey SE.

Mol Biol Cell. 2013 Mar;24(5):578-87. doi: 10.1091/mbc.E12-11-0825. Epub 2013 Jan 9.

PMID:
23303250
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas.

Palles C, Cazier JB, Howarth KM, Domingo E, Jones AM, Broderick P, Kemp Z, Spain SL, Guarino E, Salguero I, Sherborne A, Chubb D, Carvajal-Carmona LG, Ma Y, Kaur K, Dobbins S, Barclay E, Gorman M, Martin L, Kovac MB, Humphray S; CORGI Consortium; WGS500 Consortium, Lucassen A, Holmes CC, Bentley D, Donnelly P, Taylor J, Petridis C, Roylance R, Sawyer EJ, Kerr DJ, Clark S, Grimes J, Kearsey SE, Thomas HJ, McVean G, Houlston RS, Tomlinson I.

Nat Genet. 2013 Feb;45(2):136-44. doi: 10.1038/ng.2503. Epub 2012 Dec 23. Erratum in: Nat Genet. 2013 Jun;45(6):713. Guarino Almeida, Estrella [corrected to Guarino, Estrella].

PMID:
23263490
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Conditional inactivation of replication proteins in fission yeast using hormone-binding domains.

Pai CC, Schnick J, MacNeill SA, Kearsey SE.

Methods. 2012 Jun;57(2):227-33. doi: 10.1016/j.ymeth.2012.03.032. Epub 2012 Apr 5.

PMID:
22504526
[PubMed - indexed for MEDLINE]
7.

Ribonucleotide reductase activity is coupled to DNA synthesis via proliferating cell nuclear antigen.

Salguero I, Guarino E, Shepherd ME, Deegan TD, Havens CG, MacNeill SA, Walter JC, Kearsey SE.

Curr Biol. 2012 Apr 24;22(8):720-6. doi: 10.1016/j.cub.2012.02.070. Epub 2012 Mar 29.

PMID:
22464192
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Direct role for proliferating cell nuclear antigen in substrate recognition by the E3 ubiquitin ligase CRL4Cdt2.

Havens CG, Shobnam N, Guarino E, Centore RC, Zou L, Kearsey SE, Walter JC.

J Biol Chem. 2012 Mar 30;287(14):11410-21. doi: 10.1074/jbc.M111.337683. Epub 2012 Feb 2.

PMID:
22303007
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Cdt1 proteolysis is promoted by dual PIP degrons and is modulated by PCNA ubiquitylation.

Guarino E, Shepherd ME, Salguero I, Hua H, Deegan RS, Kearsey SE.

Nucleic Acids Res. 2011 Aug;39(14):5978-90. doi: 10.1093/nar/gkr222. Epub 2011 Apr 14.

PMID:
21493688
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Monitoring DNA replication in fission yeast by incorporation of 5-ethynyl-2'-deoxyuridine.

Hua H, Kearsey SE.

Nucleic Acids Res. 2011 May;39(9):e60. doi: 10.1093/nar/gkr063. Epub 2011 Feb 9.

PMID:
21310713
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast.

Moss J, Tinline-Purvis H, Walker CA, Folkes LK, Stratford MR, Hayles J, Hoe KL, Kim DU, Park HO, Kearsey SE, Fleck O, Holmberg C, Nielsen O, Humphrey TC.

Genes Dev. 2010 Dec 1;24(23):2705-16. doi: 10.1101/gad.1970810.

PMID:
21123655
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Vgl1, a multi-KH domain protein, is a novel component of the fission yeast stress granules required for cell survival under thermal stress.

Wen WL, Stevenson AL, Wang CY, Chen HJ, Kearsey SE, Norbury CJ, Watt S, Bähler J, Wang SW.

Nucleic Acids Res. 2010 Oct;38(19):6555-66. doi: 10.1093/nar/gkq555. Epub 2010 Jun 14.

PMID:
20547592
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Using the DHFR heat-inducible degron for protein inactivation in Schizosaccharomyces pombe.

Kearsey SE, Gregan J.

Methods Mol Biol. 2009;521:483-92. doi: 10.1007/978-1-60327-815-7_27.

PMID:
19563124
[PubMed - indexed for MEDLINE]
14.

GINS inactivation phenotypes reveal two pathways for chromatin association of replicative alpha and epsilon DNA polymerases in fission yeast.

Pai CC, García I, Wang SW, Cotterill S, Macneill SA, Kearsey SE.

Mol Biol Cell. 2009 Feb;20(4):1213-22. doi: 10.1091/mbc.E08-04-0429. Epub 2008 Dec 24.

PMID:
19109429
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

DNAReplication: a database of information and resources for the eukaryotic DNA replication community.

Cotterill S, Kearsey SE.

Nucleic Acids Res. 2009 Jan;37(Database issue):D837-9. doi: 10.1093/nar/gkn726. Epub 2008 Oct 17.

PMID:
18931374
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Rapid regulation of protein activity in fission yeast.

Bøe CA, Garcia I, Pai CC, Sharom JR, Skjølberg HC, Boye E, Kearsey S, Macneill SA, Tyers MD, Grallert B.

BMC Cell Biol. 2008 May 5;9:23. doi: 10.1186/1471-2121-9-23.

PMID:
18457584
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Global role for polyadenylation-assisted nuclear RNA degradation in posttranscriptional gene silencing.

Wang SW, Stevenson AL, Kearsey SE, Watt S, Bähler J.

Mol Cell Biol. 2008 Jan;28(2):656-65. Epub 2007 Nov 19.

PMID:
18025105
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The kinetochore proteins Pcs1 and Mde4 and heterochromatin are required to prevent merotelic orientation.

Gregan J, Riedel CG, Pidoux AL, Katou Y, Rumpf C, Schleiffer A, Kearsey SE, Shirahige K, Allshire RC, Nasmyth K.

Curr Biol. 2007 Jul 17;17(14):1190-200.

PMID:
17627824
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A novel checkpoint mechanism regulating the G1/S transition.

Tvegård T, Soltani H, Skjølberg HC, Krohn M, Nilssen EA, Kearsey SE, Grallert B, Boye E.

Genes Dev. 2007 Mar 15;21(6):649-54. Erratum in: Genes Dev. 2007 May 15;21(10):1273.

PMID:
17369398
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Fission yeast Cut8 is required for the repair of DNA double-strand breaks, ribosomal DNA maintenance, and cell survival in the absence of Rqh1 helicase.

Kearsey SE, Stevenson AL, Toda T, Wang SW.

Mol Cell Biol. 2007 Mar;27(5):1558-67. Epub 2006 Dec 18.

PMID:
17178839
[PubMed - indexed for MEDLINE]
Free PMC Article
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