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Results: 1 to 20 of 317

1.

Processed pseudogene insertions in somatic cells.

Kazazian HH Jr.

Mob DNA. 2014 Jul 2;5:20. doi: 10.1186/1759-8753-5-20. eCollection 2014.

PMID:
25184004
[PubMed]
Free PMC Article
2.

In vitro screening for compounds that enhance human L1 mobilization.

Terasaki N, Goodier JL, Cheung LE, Wang YJ, Kajikawa M, Kazazian HH Jr, Okada N.

PLoS One. 2013 Sep 11;8(9):e74629. doi: 10.1371/journal.pone.0074629. eCollection 2013.

PMID:
24040300
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutières syndrome-related SAMHD1.

Zhao K, Du J, Han X, Goodier JL, Li P, Zhou X, Wei W, Evans SL, Li L, Zhang W, Cheung LE, Wang G, Kazazian HH Jr, Yu XF.

Cell Rep. 2013 Sep 26;4(6):1108-15. doi: 10.1016/j.celrep.2013.08.019. Epub 2013 Sep 12.

PMID:
24035396
[PubMed - indexed for MEDLINE]
Free Article
4.

Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition.

Goodier JL, Cheung LE, Kazazian HH Jr.

Nucleic Acids Res. 2013 Aug;41(15):7401-19. doi: 10.1093/nar/gkt512. Epub 2013 Jun 9.

PMID:
23749060
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Enrichment of processed pseudogene transcripts in L1-ribonucleoprotein particles.

Mandal PK, Ewing AD, Hancks DC, Kazazian HH Jr.

Hum Mol Genet. 2013 Sep 15;22(18):3730-48. doi: 10.1093/hmg/ddt225. Epub 2013 May 21.

PMID:
23696454
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

MOV10 RNA helicase is a potent inhibitor of retrotransposition in cells.

Goodier JL, Cheung LE, Kazazian HH Jr.

PLoS Genet. 2012;8(10):e1002941. doi: 10.1371/journal.pgen.1002941. Epub 2012 Oct 18.

PMID:
23093941
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The minimal active human SVA retrotransposon requires only the 5'-hexamer and Alu-like domains.

Hancks DC, Mandal PK, Cheung LE, Kazazian HH Jr.

Mol Cell Biol. 2012 Nov;32(22):4718-26. doi: 10.1128/MCB.00860-12. Epub 2012 Sep 24.

PMID:
23007156
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Extensive somatic L1 retrotransposition in colorectal tumors.

Solyom S, Ewing AD, Rahrmann EP, Doucet T, Nelson HH, Burns MB, Harris RS, Sigmon DF, Casella A, Erlanger B, Wheelan S, Upton KR, Shukla R, Faulkner GJ, Largaespada DA, Kazazian HH Jr.

Genome Res. 2012 Dec;22(12):2328-38. doi: 10.1101/gr.145235.112. Epub 2012 Sep 11.

PMID:
22968929
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Active human retrotransposons: variation and disease.

Hancks DC, Kazazian HH Jr.

Curr Opin Genet Dev. 2012 Jun;22(3):191-203. doi: 10.1016/j.gde.2012.02.006. Epub 2012 Mar 8. Review.

PMID:
22406018
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Mobile elements in the human genome: implications for disease.

Solyom S, Kazazian HH Jr.

Genome Med. 2012 Feb 24;4(2):12. doi: 10.1186/gm311.

PMID:
22364178
[PubMed]
Free PMC Article
11.

Pathogenic orphan transduction created by a nonreference LINE-1 retrotransposon.

Solyom S, Ewing AD, Hancks DC, Takeshima Y, Awano H, Matsuo M, Kazazian HH Jr.

Hum Mutat. 2012 Feb;33(2):369-71. doi: 10.1002/humu.21663. Epub 2011 Dec 8.

PMID:
22095564
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mobile DNA transposition in somatic cells.

Kazazian HH Jr.

BMC Biol. 2011 Sep 29;9:62. doi: 10.1186/1741-7007-9-62. Review.

PMID:
21958341
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Retrotransposition of marked SVA elements by human L1s in cultured cells.

Hancks DC, Goodier JL, Mandal PK, Cheung LE, Kazazian HH Jr.

Hum Mol Genet. 2011 Sep 1;20(17):3386-400. doi: 10.1093/hmg/ddr245. Epub 2011 Jun 2.

PMID:
21636526
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Efficacy and safety of long-term prophylaxis in severe hemophilia A dogs following liver gene therapy using AAV vectors.

Sabatino DE, Lange AM, Altynova ES, Sarkar R, Zhou S, Merricks EP, Franck HG, Nichols TC, Arruda VR, Kazazian HH Jr.

Mol Ther. 2011 Mar;19(3):442-9. doi: 10.1038/mt.2010.240. Epub 2010 Nov 16.

PMID:
21081906
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Whole-genome resequencing allows detection of many rare LINE-1 insertion alleles in humans.

Ewing AD, Kazazian HH Jr.

Genome Res. 2011 Jun;21(6):985-90. doi: 10.1101/gr.114777.110. Epub 2010 Oct 27.

PMID:
20980553
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Eradication of neutralizing antibodies to factor VIII in canine hemophilia A after liver gene therapy.

Finn JD, Ozelo MC, Sabatino DE, Franck HW, Merricks EP, Crudele JM, Zhou S, Kazazian HH, Lillicrap D, Nichols TC, Arruda VR.

Blood. 2010 Dec 23;116(26):5842-8. doi: 10.1182/blood-2010-06-288001. Epub 2010 Sep 28.

PMID:
20876851
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes.

Ewing AD, Kazazian HH Jr.

Genome Res. 2010 Sep;20(9):1262-70. doi: 10.1101/gr.106419.110. Epub 2010 May 20.

PMID:
20488934
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

SVA retrotransposons: Evolution and genetic instability.

Hancks DC, Kazazian HH Jr.

Semin Cancer Biol. 2010 Aug;20(4):234-45. doi: 10.1016/j.semcancer.2010.04.001. Epub 2010 Apr 21. Review.

PMID:
20416380
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Discrete subcellular partitioning of human retrotransposon RNAs despite a common mechanism of genome insertion.

Goodier JL, Mandal PK, Zhang L, Kazazian HH Jr.

Hum Mol Genet. 2010 May 1;19(9):1712-25. doi: 10.1093/hmg/ddq048. Epub 2010 Feb 10.

PMID:
20147320
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Many LINE1 elements contribute to the transcriptome of human somatic cells.

Rangwala SH, Zhang L, Kazazian HH Jr.

Genome Biol. 2009;10(9):R100. doi: 10.1186/gb-2009-10-9-r100. Epub 2009 Sep 22.

PMID:
19772661
[PubMed - indexed for MEDLINE]
Free PMC Article

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