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Items: 1 to 20 of 328

1.

Somatically Acquired LINE-1 Insertions in Normal Esophagus Undergo Clonal Expansion in Esophageal Squamous Cell Carcinoma.

Doucet-O'Hare TT, Sharma R, Rodić N, Anders RA, Burns KH, Kazazian HH Jr.

Hum Mutat. 2016 Sep;37(9):942-54. doi: 10.1002/humu.23027. Epub 2016 Jul 13.

PMID:
27319353
2.

Roles for retrotransposon insertions in human disease.

Hancks DC, Kazazian HH Jr.

Mob DNA. 2016 May 6;7:9. doi: 10.1186/s13100-016-0065-9. eCollection 2016. Review.

3.

25 Years of Human Mutation.

Cutting GR, Kazazian HH Jr.

Hum Mutat. 2016 Jun;37(6):503-4. doi: 10.1002/humu.22988. No abstract available.

PMID:
26990436
4.

Purification of L1-Ribonucleoprotein Particles (L1-RNPs) from Cultured Human Cells.

Mandal PK, Kazazian HH Jr.

Methods Mol Biol. 2016;1400:299-310. doi: 10.1007/978-1-4939-3372-3_19.

PMID:
26895061
5.

Long Interspersed Element Sequencing (L1-Seq): A Method to Identify Somatic LINE-1 Insertions in the Human Genome.

Doucet TT, Kazazian HH Jr.

Methods Mol Biol. 2016;1400:79-93. doi: 10.1007/978-1-4939-3372-3_5.

PMID:
26895047
6.

LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma.

Doucet-O'Hare TT, Rodić N, Sharma R, Darbari I, Abril G, Choi JA, Young Ahn J, Cheng Y, Anders RA, Burns KH, Meltzer SJ, Kazazian HH Jr.

Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4894-900. doi: 10.1073/pnas.1502474112. Epub 2015 Aug 17. Erratum in: Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E104.

7.

Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution.

Ewing AD, Gacita A, Wood LD, Ma F, Xing D, Kim MS, Manda SS, Abril G, Pereira G, Makohon-Moore A, Looijenga LH, Gillis AJ, Hruban RH, Anders RA, Romans KE, Pandey A, Iacobuzio-Donahue CA, Vogelstein B, Kinzler KW, Kazazian HH Jr, Solyom S.

Genome Res. 2015 Oct;25(10):1536-45. doi: 10.1101/gr.196238.115. Epub 2015 Aug 10.

8.

In Memoriam: Richard G.H. Cotton (1940-2015).

Kazazian HH Jr, Paalman MH, Cutting GR.

Hum Mutat. 2015 Aug;36(8):741-2. doi: 10.1002/humu.22826. Epub 2015 Jul 3. No abstract available.

PMID:
26148136
9.

The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition.

Goodier JL, Pereira GC, Cheung LE, Rose RJ, Kazazian HH Jr.

PLoS Genet. 2015 May 22;11(5):e1005252. doi: 10.1371/journal.pgen.1005252. eCollection 2015 May.

10.

2014 William Allan Award introduction: Stuart Orkin.

Kazazian HH Jr.

Am J Hum Genet. 2015 Mar 5;96(3):352-3. doi: 10.1016/j.ajhg.2014.11.018. No abstract available.

11.

Processed pseudogene insertions in somatic cells.

Kazazian HH Jr.

Mob DNA. 2014 Jul 2;5:20. doi: 10.1186/1759-8753-5-20. eCollection 2014.

12.

In vitro screening for compounds that enhance human L1 mobilization.

Terasaki N, Goodier JL, Cheung LE, Wang YJ, Kajikawa M, Kazazian HH Jr, Okada N.

PLoS One. 2013 Sep 11;8(9):e74629. doi: 10.1371/journal.pone.0074629. eCollection 2013.

13.

Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutières syndrome-related SAMHD1.

Zhao K, Du J, Han X, Goodier JL, Li P, Zhou X, Wei W, Evans SL, Li L, Zhang W, Cheung LE, Wang G, Kazazian HH Jr, Yu XF.

Cell Rep. 2013 Sep 26;4(6):1108-15. doi: 10.1016/j.celrep.2013.08.019. Epub 2013 Sep 12.

14.

Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition.

Goodier JL, Cheung LE, Kazazian HH Jr.

Nucleic Acids Res. 2013 Aug;41(15):7401-19. doi: 10.1093/nar/gkt512. Epub 2013 Jun 9.

15.

Enrichment of processed pseudogene transcripts in L1-ribonucleoprotein particles.

Mandal PK, Ewing AD, Hancks DC, Kazazian HH Jr.

Hum Mol Genet. 2013 Sep 15;22(18):3730-48. doi: 10.1093/hmg/ddt225. Epub 2013 May 21.

16.

MOV10 RNA helicase is a potent inhibitor of retrotransposition in cells.

Goodier JL, Cheung LE, Kazazian HH Jr.

PLoS Genet. 2012;8(10):e1002941. doi: 10.1371/journal.pgen.1002941. Epub 2012 Oct 18.

17.

The minimal active human SVA retrotransposon requires only the 5'-hexamer and Alu-like domains.

Hancks DC, Mandal PK, Cheung LE, Kazazian HH Jr.

Mol Cell Biol. 2012 Nov;32(22):4718-26. doi: 10.1128/MCB.00860-12. Epub 2012 Sep 24.

18.

Extensive somatic L1 retrotransposition in colorectal tumors.

Solyom S, Ewing AD, Rahrmann EP, Doucet T, Nelson HH, Burns MB, Harris RS, Sigmon DF, Casella A, Erlanger B, Wheelan S, Upton KR, Shukla R, Faulkner GJ, Largaespada DA, Kazazian HH Jr.

Genome Res. 2012 Dec;22(12):2328-38. doi: 10.1101/gr.145235.112. Epub 2012 Sep 11.

19.

Active human retrotransposons: variation and disease.

Hancks DC, Kazazian HH Jr.

Curr Opin Genet Dev. 2012 Jun;22(3):191-203. doi: 10.1016/j.gde.2012.02.006. Epub 2012 Mar 8. Review.

20.

Mobile elements in the human genome: implications for disease.

Solyom S, Kazazian HH Jr.

Genome Med. 2012 Feb 24;4(2):12. doi: 10.1186/gm311.

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