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Results: 1 to 20 of 57

1.

Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation.

Mould AW, Pang Z, Pakusch M, Tonks ID, Stark M, Carrie D, Mukhopadhyay P, Seidel A, Ellis JJ, Deakin J, Wakefield MJ, Krause L, Blewitt ME, Kay GF.

Epigenetics Chromatin. 2013 Jul 2;6(1):19. doi: 10.1186/1756-8935-6-19.

PMID:
23819640
[PubMed]
Free PMC Article
2.

No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations.

Youngson NA, Epp T, Roberts AR, Daxinger L, Ashe A, Huang E, Lester KL, Harten SK, Kay GF, Cox T, Matthews JM, Chong S, Whitelaw E.

Mamm Genome. 2013 Jun;24(5-6):206-17. doi: 10.1007/s00335-013-9451-5. Epub 2013 May 1.

PMID:
23636699
[PubMed - indexed for MEDLINE]
3.

Menin and p53 have non-synergistic effects on tumorigenesis in mice.

Loffler KA, Mould AW, Waring PM, Hayward NK, Kay GF.

BMC Cancer. 2012 Jun 18;12:252. doi: 10.1186/1471-2407-12-252.

PMID:
22708734
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Brca1 is involved in establishing murine pigmentation in a p53 and developmentally specific manner.

Tonks ID, Walker GJ, Mould AW, Ferguson B, Keith P, Hayward NK, Kay GF.

Pigment Cell Melanoma Res. 2012 Jul;25(4):530-2. doi: 10.1111/j.1755-148X.2012.01009.x. Epub 2012 Jun 1. No abstract available.

PMID:
22540872
[PubMed - indexed for MEDLINE]
5.

The A-repeat links ASF/SF2-dependent Xist RNA processing with random choice during X inactivation.

Royce-Tolland ME, Andersen AA, Koyfman HR, Talbot DJ, Wutz A, Tonks ID, Kay GF, Panning B.

Nat Struct Mol Biol. 2010 Aug;17(8):948-54. doi: 10.1038/nsmb.1877. Epub 2010 Jul 25.

PMID:
20657585
[PubMed - indexed for MEDLINE]
6.

Alterations in gene expression in MEN1-associated insulinoma development.

Serewko-Auret MM, Mould AW, Loffler KA, Duncan R, Kay GF, Hayward NK.

Pancreas. 2010 Nov;39(8):1140-6. doi: 10.1097/MPA.0b013e3181dc67fc.

PMID:
20531244
[PubMed - indexed for MEDLINE]
7.

Melanocyte homeostasis in vivo tolerates Rb1 loss in a developmentally independent fashion.

Tonks ID, Mould AW, Schroder WA, Hacker E, Bosenberg M, Hayward NK, Walker GJ, Kay GF.

Pigment Cell Melanoma Res. 2010 Aug;23(4):564-70. doi: 10.1111/j.1755-148X.2010.00722.x. Epub 2010 May 26.

PMID:
20518858
[PubMed - indexed for MEDLINE]
8.

Dual loss of rb1 and Trp53 in the adrenal medulla leads to spontaneous pheochromocytoma.

Tonks ID, Mould AW, Schroder WA, Cotterill A, Hayward NK, Walker GJ, Kay GF.

Neoplasia. 2010 Mar;12(3):235-43.

PMID:
20234817
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The glycosylphosphatidylinositol-anchored serine protease PRSS21 (testisin) imparts murine epididymal sperm cell maturation and fertilizing ability.

Netzel-Arnett S, Bugge TH, Hess RA, Carnes K, Stringer BW, Scarman AL, Hooper JD, Tonks ID, Kay GF, Antalis TM.

Biol Reprod. 2009 Nov;81(5):921-32. doi: 10.1095/biolreprod.109.076273. Epub 2009 Jul 1.

PMID:
19571264
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Dual loss of Rb1 and Trp53 in melanocytes perturbs melanocyte homeostasis and genetic stability in vitro but does not cause melanoma or pigmentation defects in vivo.

Tonks ID, Mould A, Nurcombe V, Cool SM, Walker GJ, Hacker E, Keith P, Schroder WA, Cotterill A, Hayward NK, Kay GF.

Pigment Cell Melanoma Res. 2009 Jun;22(3):328-30. doi: 10.1111/j.1755-148X.2009.00560.x. Epub 2009 Feb 25. No abstract available.

PMID:
19243574
[PubMed - indexed for MEDLINE]
11.

Global expression profiling of sex cord stromal tumors from Men1 heterozygous mice identifies altered TGF-beta signaling, decreased Gata6 and increased Csf1r expression.

Mould AW, Duncan R, Serewko-Auret M, Loffler KA, Biondi C, Gartside M, Kay GF, Hayward NK.

Int J Cancer. 2009 Mar 1;124(5):1122-32. doi: 10.1002/ijc.24057.

PMID:
19058182
[PubMed - indexed for MEDLINE]
12.

Skewed X chromosome inactivation and breast and ovarian cancer status: evidence for X-linked modifiers of BRCA1.

Lose F, Duffy DL, Kay GF, Kedda MA, Spurdle AB; Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer; Australian Ovarian Cancer Study Management Group.

J Natl Cancer Inst. 2008 Nov 5;100(21):1519-29. doi: 10.1093/jnci/djn345. Epub 2008 Oct 28.

PMID:
18957670
[PubMed - indexed for MEDLINE]
Free Article
13.

Tissue-specific ablation of Prkar1a causes schwannomas by suppressing neurofibromatosis protein production.

Jones GN, Tep C, Towns WH 2nd, Mihai G, Tonks ID, Kay GF, Schmalbrock PM, Stemmer-Rachamimov AO, Yoon SO, Kirschner LS.

Neoplasia. 2008 Nov;10(11):1213-21.

PMID:
18953430
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Generation and characterization of EphA1 receptor tyrosine kinase reporter knockout mice.

Duffy SL, Coulthard MG, Spanevello MD, Herath NI, Yeadon TM, McCarron JK, Carter JC, Tonks ID, Kay GF, Phillips GE, Boyd AW.

Genesis. 2008 Oct;46(10):553-61. doi: 10.1002/dvg.20434.

PMID:
18802966
[PubMed - indexed for MEDLINE]
15.

SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation.

Blewitt ME, Gendrel AV, Pang Z, Sparrow DB, Whitelaw N, Craig JM, Apedaile A, Hilton DJ, Dunwoodie SL, Brockdorff N, Kay GF, Whitelaw E.

Nat Genet. 2008 May;40(5):663-9. doi: 10.1038/ng.142. Epub 2008 Apr 20.

PMID:
18425126
[PubMed - indexed for MEDLINE]
16.

Prophylactic but not therapeutic activity of a monoclonal antibody that neutralizes the binding of VEGF-B to VEGFR-1 in a murine collagen-induced arthritis model.

Mould AW, Scotney P, Greco SA, Hayward NK, Nash A, Kay GF.

Rheumatology (Oxford). 2008 Mar;47(3):263-6. doi: 10.1093/rheumatology/kem369. Epub 2008 Jan 19.

PMID:
18204088
[PubMed - indexed for MEDLINE]
Free Article
17.

Global expression profiling of murine MEN1-associated tumors reveals a regulatory role for menin in transcription, cell cycle and chromatin remodelling.

Mould AW, Duncan R, Serewko-Auret M, Loffler KA, Biondi C, Gartside M, Kay GF, Hayward NK.

Int J Cancer. 2007 Aug 15;121(4):776-83.

PMID:
17455252
[PubMed - indexed for MEDLINE]
18.

Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice.

Loffler KA, Biondi CA, Gartside MG, Serewko-Auret MM, Duncan R, Tonks ID, Mould AW, Waring P, Muller HK, Kay GF, Hayward NK.

Oncogene. 2007 Jun 7;26(27):4009-17. Epub 2006 Dec 18.

PMID:
17173065
[PubMed - indexed for MEDLINE]
19.

Broad tumor spectrum in a mouse model of multiple endocrine neoplasia type 1.

Loffler KA, Biondi CA, Gartside M, Waring P, Stark M, Serewko-Auret MM, Muller HK, Hayward NK, Kay GF.

Int J Cancer. 2007 Jan 15;120(2):259-67.

PMID:
17044021
[PubMed - indexed for MEDLINE]
20.

Pocket protein function in melanocyte homeostasis and neoplasia.

Tonks ID, Hayward NK, Kay GF.

Pigment Cell Res. 2006 Aug;19(4):260-83. Review.

PMID:
16827746
[PubMed - indexed for MEDLINE]

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