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Results: 7

1.

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.

Vizeacoumar FJ, Arnold R, Vizeacoumar FS, Chandrashekhar M, Buzina A, Young JT, Kwan JH, Sayad A, Mero P, Lawo S, Tanaka H, Brown KR, Baryshnikova A, Mak AB, Fedyshyn Y, Wang Y, Brito GC, Kasimer D, Makhnevych T, Ketela T, Datti A, Babu M, Emili A, Pelletier L, Wrana J, Wainberg Z, Kim PM, Rottapel R, O'Brien CA, Andrews B, Boone C, Moffat J.

Mol Syst Biol. 2013 Oct 8;9:696. doi: 10.1038/msb.2013.54.

PMID:
24104479
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Essential gene profiles in breast, pancreatic, and ovarian cancer cells.

Marcotte R, Brown KR, Suarez F, Sayad A, Karamboulas K, Krzyzanowski PM, Sircoulomb F, Medrano M, Fedyshyn Y, Koh JL, van Dyk D, Fedyshyn B, Luhova M, Brito GC, Vizeacoumar FJ, Vizeacoumar FS, Datti A, Kasimer D, Buzina A, Mero P, Misquitta C, Normand J, Haider M, Ketela T, Wrana JL, Rottapel R, Neel BG, Moffat J.

Cancer Discov. 2012 Feb;2(2):172-89. doi: 10.1158/2159-8290.CD-11-0224. Epub 2011 Dec 29.

PMID:
22585861
[PubMed - indexed for MEDLINE]
3.

A genome wide shRNA screen identifies α/β hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance.

Simpson CD, Hurren R, Kasimer D, MacLean N, Eberhard Y, Ketela T, Moffat J, Schimmer AD.

Apoptosis. 2012 Jul;17(7):666-78. doi: 10.1007/s10495-012-0723-4.

PMID:
22488300
[PubMed - indexed for MEDLINE]
4.

COLT-Cancer: functional genetic screening resource for essential genes in human cancer cell lines.

Koh JL, Brown KR, Sayad A, Kasimer D, Ketela T, Moffat J.

Nucleic Acids Res. 2012 Jan;40(Database issue):D957-63. doi: 10.1093/nar/gkr959. Epub 2011 Nov 18.

PMID:
22102578
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

CD133 protein N-glycosylation processing contributes to cell surface recognition of the primitive cell marker AC133 epitope.

Mak AB, Blakely KM, Williams RA, Penttilä PA, Shukalyuk AI, Osman KT, Kasimer D, Ketela T, Moffat J.

J Biol Chem. 2011 Nov 25;286(47):41046-56. doi: 10.1074/jbc.M111.261545. Epub 2011 Sep 21.

PMID:
21937449
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A comprehensive platform for highly multiplexed mammalian functional genetic screens.

Ketela T, Heisler LE, Brown KR, Ammar R, Kasimer D, Surendra A, Ericson E, Blakely K, Karamboulas D, Smith AM, Durbic T, Arnoldo A, Cheung-Ong K, Koh JL, Gopal S, Cowley GS, Yang X, Grenier JK, Giaever G, Root DE, Moffat J, Nislow C.

BMC Genomics. 2011 May 6;12:213. doi: 10.1186/1471-2164-12-213.

PMID:
21548937
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Menin links the stress response to genome stability in Drosophila melanogaster.

Papaconstantinou M, Pepper AN, Wu Y, Kasimer D, Westwood T, Campos AR, Bédard PA.

PLoS One. 2010 Nov 18;5(11):e14049. doi: 10.1371/journal.pone.0014049.

PMID:
21124979
[PubMed - indexed for MEDLINE]
Free PMC Article

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