PubMed

Quantifying the HIV-1 integrase inhibitor raltegravir in female genital tract secretions using high-performance liquid chromatography with ultraviolet detection.

Talameh JA, Rezk NL, Kashuba AD.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Nov 13. [Epub ahead of print]PMID: 19942487 [PubMed - as supplied by publisher]

CYP2B6 variants and plasma efavirenz concentrations during antiretroviral therapy in Port-au-Prince, Haiti.

Leger P, Dillingham R, Beauharnais CA, Kashuba AD, Rezk NL, Fitzgerald DW, Pape JW, Haas DW.

J Infect Dis. 2009 Sep 15;200(6):955-64.PMID: 19659438 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel LC-ESI-MS method for the simultaneous determination of etravirine, darunavir and ritonavir in human blood plasma.

Rezk NL, White NR, Jennings SH, Kashuba AD.

Talanta. 2009 Oct 15;79(5):1372-8. Epub 2009 Jun 9.PMID: 19635373 [PubMed - indexed for MEDLINE]Related articles

Interindividual variability in pharmacokinetics of generic nucleoside reverse transcriptase inhibitors in TB/HIV-coinfected Ghanaian patients: UGT2B7*1c is associated with faster zidovudine clearance and glucuronidation.

Kwara A, Lartey M, Boamah I, Rezk NL, Oliver-Commey J, Kenu E, Kashuba AD, Court MH.

J Clin Pharmacol. 2009 Sep;49(9):1079-90. Epub 2009 Jul 23.PMID: 19628728 [PubMed - indexed for MEDLINE]Related articles

Maraviroc concentrates in the cervicovaginal fluid and vaginal tissue of HIV-negative women.

Dumond JB, Patterson KB, Pecha AL, Werner RE, Andrews E, Damle B, Tressler R, Worsley J, Kashuba AD.

J Acquir Immune Defic Syndr. 2009 Aug 15;51(5):546-53.PMID: 19546811 [PubMed - indexed for MEDLINE]Related articles

Suppression of human immunodeficiency virus type 1 (HIV-1) viremia with reverse transcriptase and integrase inhibitors, CD4+ T-cell recovery, and viral rebound upon interruption of therapy in a new model for HIV treatment in the humanized Rag2-/-{gamma}c-/- mouse.

Choudhary SK, Rezk NL, Ince WL, Cheema M, Zhang L, Su L, Swanstrom R, Kashuba AD, Margolis DM.

J Virol. 2009 Aug;83(16):8254-8. Epub 2009 Jun 3.PMID: 19494021 [PubMed - indexed for MEDLINE]Related articles

Drug interactions with new and investigational antiretrovirals.

Brown KC, Paul S, Kashuba AD.

Clin Pharmacokinet. 2009;48(4):211-41. doi: 10.2165/00003088-200948040-00001. Review.PMID: 19492868 [PubMed - indexed for MEDLINE]Related articles

Evaluating nurses' implementation of an infant-feeding counseling protocol for HIV-infected mothers: The Ban Study in Lilongwe, Malawi.

Ferguson YO, Eng E, Bentley M, Sandelowski M, Steckler A, Randall-David E, Piwoz EG, Zulu C, Chasela C, Soko A, Tembo M, Martinson F, Tohill BC, Ahmed Y, Kazembe P, Jamieson DJ, van der Horst C; UNC Project BAN Study Team, Adair L, Ahmed Y, Ait-Khaled M, Albrecht S, Bangdiwala S, Bayer R, Bentley M, Bramson B, Bobrow E, Boyle N, Butera S, Chasela C, Chavula C, Chimerang'ambe J, Chigwenembe M, Chikasema M, Chikhungu N, Chilongozi D, Chiudzu G, Chome L, Cole A, Corbett A, Corneli A, Duerr A, Eliya H, Ellington S, Eron J, Farr S, Ferguson YO, Fiscus S, Galvin S, Guay L, Heilig C, Hoffman I, Hooten E, Hosseinipour M, Hudgens M, Hurst S, Hyde L, Jamieson D, Joaki G, Jones D, Kacheche Z, Kamanga E, Kamanga G, Kampani C, Kamthunzi P, Kamwendo D, Kanyama C, Kashuba A, Kathyola D, Kayira D, Kazembe P, Knight R, Kourtis A, Krysiak R, Kumwenda J, Loeliger E, Luhanga M, Madhlopa V, Majawa M, Maida A, Marcus C, Martinson F, Thoofer N, Matika C, Mayers D, Mayuni I, McDonough M, Meme J, Merry C, Mita K, Mkomawanthu C, Mndala G, Mndala I, Moses A, Msika A, Msungama W, Mtimuni B, Muita J, Mumba N, Musis B, Mwansambo C, Mwapasa G, Nkhoma J, Pendame R, Piwoz E, Raines B, Ramdas Z, Rublein J, Ryan M, Sanne I, Sellers C, Shugars D, Sichali D, Snowden W, Soko A, Spensley A, Steens JM, Tegha G, Tembo M, Thomas R, Tien HC, Tohill B, van der Horst C, Waalberg E, Wiener J, Wilfert C, Wiyo P, Zgambo O, Zimba C.

AIDS Educ Prev. 2009 Apr;21(2):141-55.PMID: 19397436 [PubMed - indexed for MEDLINE]Related articles

Genital tract, cord blood, and amniotic fluid exposures of seven antiretroviral drugs during and after pregnancy in human immunodeficiency virus type 1-infected women.

Yeh RF, Rezk NL, Kashuba AD, Dumond JB, Tappouni HL, Tien HC, Chen YC, Vourvahis M, Horton AL, Fiscus SA, Patterson KB.

Antimicrob Agents Chemother. 2009 Jun;53(6):2367-74. Epub 2009 Mar 23.PMID: 19307360 [PubMed - indexed for MEDLINE]Related articles

Identification of a cranberry juice product that inhibits enteric CYP3A-mediated first-pass metabolism in humans.

Ngo N, Yan Z, Graf TN, Carrizosa DR, Kashuba AD, Dees EC, Oberlies NH, Paine MF.

Drug Metab Dispos. 2009 Mar;37(3):514-22. Epub 2008 Dec 29.PMID: 19114462 [PubMed - indexed for MEDLINE]Related articlesFree article

An accurate and precise high-performance liquid chromatography method for the rapid quantification of the novel HIV integrase inhibitor raltegravir in human blood plasma after solid phase extraction.

Rezk NL, White N, Kashuba AD.

Anal Chim Acta. 2008 Nov 3;628(2):204-13. Epub 2008 Sep 11.PMID: 18929009 [PubMed - indexed for MEDLINE]Related articles

Studies on Antiretroviral Drug Concentrations in Breast Milk: Validation of a Liquid Chromatography-Tandem Mass Spectrometric Method for the Determination of 7 Anti-Human Immunodeficiency Virus Medications.

Rezk NL, White N, Bridges AS, Abdel-Megeed MF, Mohamed TM, Moselhy SS, Kashuba AD.

Ther Drug Monit. 2008 Aug 27. [Epub ahead of print]PMID: 18758393 [PubMed - as supplied by publisher]Related articles

Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel.

Cranage M, Sharpe S, Herrera C, Cope A, Dennis M, Berry N, Ham C, Heeney J, Rezk N, Kashuba A, Anton P, McGowan I, Shattock R.

PLoS Med. 2008 Aug 5;5(8):e157; discussion e157.PMID: 18684007 [PubMed - indexed for MEDLINE]Related articlesFree article

The pharmacokinetics of silymarin is altered in patients with hepatitis C virus and nonalcoholic Fatty liver disease and correlates with plasma caspase-3/7 activity.

Schrieber SJ, Wen Z, Vourvahis M, Smith PC, Fried MW, Kashuba AD, Hawke RL.

Drug Metab Dispos. 2008 Sep;36(9):1909-16. Epub 2008 Jun 19.PMID: 18566043 [PubMed - indexed for MEDLINE]Related articlesFree article

The influence of CYP3A5 genotype on dexamethasone induction of CYP3A activity in African Americans.

Roberts PJ, Rollins KD, Kashuba AD, Paine MF, Nelsen AC, Williams EE, Moran C, Lamba JK, Schuetz EG, Hawke RL.

Drug Metab Dispos. 2008 Aug;36(8):1465-9. Epub 2008 May 19.PMID: 18490434 [PubMed - indexed for MEDLINE]Related articlesFree article

Randomized study of dual versus single ritonavir-enhanced protease inhibitors for protease inhibitor-experienced patients with HIV.

Collier AC, Tierney C, Downey GF, Eshleman SH, Kashuba A, Klingman K, Vergis EN, Pakes GE, Rooney JF, Rinehart A, Mellors JW; AIDS Clinical Trials Group Protocol A5143 Team.

HIV Clin Trials. 2008 Mar-Apr;9(2):91-102.PMID: 18474494 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential extracellular and intracellular concentrations of zidovudine and lamivudine in semen and plasma of HIV-1-infected men.

Dumond JB, Reddy YS, Troiani L, Rodriguez JF, Bridges AS, Fiscus SA, Yuen GJ, Cohen MS, Kashuba AD.

J Acquir Immune Defic Syndr. 2008 Jun 1;48(2):156-62.PMID: 18360288 [PubMed - indexed for MEDLINE]Related articles

Effect of low-dose ritonavir on the pharmacokinetics of the CXCR4 antagonist AMD070 in healthy volunteers.

Cao YJ, Flexner CW, Dunaway S, Park JG, Klingman K, Wiggins I, Conley J, Radebaugh C, Kashuba AD, MacFarland R, Becker S, Hendrix CW.

Antimicrob Agents Chemother. 2008 May;52(5):1630-4. Epub 2008 Feb 19.PMID: 18285477 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of omeprazole on the plasma concentrations of indinavir when administered alone and in combination with ritonavir.

Tappouni HL, Rublein JC, Donovan BJ, Hollowell SB, Tien HC, Min SS, Theodore D, Rezk NL, Smith PC, Tallman MN, Raasch RH, Kashuba AD.

Am J Health Syst Pharm. 2008 Mar 1;65(5):422-8.PMID: 18281734 [PubMed - indexed for MEDLINE]Related articlesFree article

Antiretroviral therapy for prevention of HIV infection: new clues from an animal model.

Cohen MS, Kashuba AD.

PLoS Med. 2008 Feb;5(2):e30. Review. No abstract available. PMID: 18254655 [PubMed - indexed for MEDLINE]Related articlesFree article