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Results: 1 to 20 of 84

1.

Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.

Walmacq C, Wang L, Chong J, Scibelli K, Lubkowska L, Gnatt A, Brooks PJ, Wang D, Kashlev M.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E410-9. doi: 10.1073/pnas.1415186112. Epub 2015 Jan 20.

PMID:
25605892
[PubMed - in process]
Free PMC Article
2.

A genetic assay for transcription errors reveals multilayer control of RNA polymerase II fidelity.

Irvin JD, Kireeva ML, Gotte DR, Shafer BK, Huang I, Kashlev M, Strathern JN.

PLoS Genet. 2014 Sep 18;10(9):e1004532. doi: 10.1371/journal.pgen.1004532. eCollection 2014 Sep.

PMID:
25232834
[PubMed - in process]
Free PMC Article
3.

Coliphage HK022 Nun protein inhibits RNA polymerase translocation.

Vitiello CL, Kireeva ML, Lubkowska L, Kashlev M, Gottesman M.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):E2368-75. doi: 10.1073/pnas.1319740111. Epub 2014 May 22.

PMID:
24853501
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Unveiling translocation intermediates of RNA polymerase.

Imashimizu M, Kashlev M.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7507-8. doi: 10.1073/pnas.1406413111. Epub 2014 May 14. No abstract available.

PMID:
24828529
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

In silico design and enzymatic synthesis of functional RNA nanoparticles.

Afonin KA, Kasprzak WK, Bindewald E, Kireeva M, Viard M, Kashlev M, Shapiro BA.

Acc Chem Res. 2014 Jun 17;47(6):1731-41. doi: 10.1021/ar400329z. Epub 2014 Apr 23.

PMID:
24758371
[PubMed - in process]
6.

Bacteriophage λ N protein inhibits transcription slippage by Escherichia coli RNA polymerase.

Parks AR, Court C, Lubkowska L, Jin DJ, Kashlev M, Court DL.

Nucleic Acids Res. 2014 May;42(9):5823-9. doi: 10.1093/nar/gku203. Epub 2014 Apr 7.

PMID:
24711367
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Transcription elongation: Heterogeneous tracking of RNA polymerase and its biological implications.

Imashimizu M, Shimamoto N, Oshima T, Kashlev M.

Transcription. 2014 Feb 21;5. [Epub ahead of print] Review.

PMID:
24642570
[PubMed - as supplied by publisher]
Free Article
8.

Transcription factors IIS and IIF enhance transcription efficiency by differentially modifying RNA polymerase pausing dynamics.

Ishibashi T, Dangkulwanich M, Coello Y, Lionberger TA, Lubkowska L, Ponticelli AS, Kashlev M, Bustamante C.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3419-24. doi: 10.1073/pnas.1401611111. Epub 2014 Feb 18.

PMID:
24550488
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

RNA polymerase structure, function, regulation, dynamics, fidelity, and roles in gene expression.

Kireeva ML, Kashlev M, Burton ZF.

Chem Rev. 2013 Nov 13;113(11):8325-30. doi: 10.1021/cr400436m. No abstract available.

PMID:
24219496
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Co-transcriptional production of RNA-DNA hybrids for simultaneous release of multiple split functionalities.

Afonin KA, Desai R, Viard M, Kireeva ML, Bindewald E, Case CL, Maciag AE, Kasprzak WK, Kim T, Sappe A, Stepler M, Kewalramani VN, Kashlev M, Blumenthal R, Shapiro BA.

Nucleic Acids Res. 2014 Feb;42(3):2085-97. doi: 10.1093/nar/gkt1001. Epub 2013 Nov 4.

PMID:
24194608
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism.

Dangkulwanich M, Ishibashi T, Liu S, Kireeva ML, Lubkowska L, Kashlev M, Bustamante CJ.

Elife. 2013 Sep 24;2:e00971. doi: 10.7554/eLife.00971.

PMID:
24066225
[PubMed - in process]
Free PMC Article
12.

Direct assessment of transcription fidelity by high-resolution RNA sequencing.

Imashimizu M, Oshima T, Lubkowska L, Kashlev M.

Nucleic Acids Res. 2013 Oct;41(19):9090-104. doi: 10.1093/nar/gkt698. Epub 2013 Aug 7.

PMID:
23925128
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Intrinsic translocation barrier as an initial step in pausing by RNA polymerase II.

Imashimizu M, Kireeva ML, Lubkowska L, Gotte D, Parks AR, Strathern JN, Kashlev M.

J Mol Biol. 2013 Feb 22;425(4):697-712. doi: 10.1016/j.jmb.2012.12.002. Epub 2012 Dec 10.

PMID:
23238253
[PubMed - indexed for MEDLINE]
14.

Isolation and characterization of RNA polymerase rpoB mutations that alter transcription slippage during elongation in Escherichia coli.

Zhou YN, Lubkowska L, Hui M, Court C, Chen S, Court DL, Strathern J, Jin DJ, Kashlev M.

J Biol Chem. 2013 Jan 25;288(4):2700-10. doi: 10.1074/jbc.M112.429464. Epub 2012 Dec 5.

PMID:
23223236
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The fidelity of transcription: RPB1 (RPO21) mutations that increase transcriptional slippage in S. cerevisiae.

Strathern J, Malagon F, Irvin J, Gotte D, Shafer B, Kireeva M, Lubkowska L, Jin DJ, Kashlev M.

J Biol Chem. 2013 Jan 25;288(4):2689-99. doi: 10.1074/jbc.M112.429506. Epub 2012 Dec 5.

PMID:
23223234
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The RNA polymerase bridge helix YFI motif in catalysis, fidelity and translocation.

Nedialkov YA, Opron K, Assaf F, Artsimovitch I, Kireeva ML, Kashlev M, Cukier RI, Nudler E, Burton ZF.

Biochim Biophys Acta. 2013 Feb;1829(2):187-98. doi: 10.1016/j.bbagrm.2012.11.005. Epub 2012 Nov 30.

PMID:
23202476
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides.

Arnold JJ, Sharma SD, Feng JY, Ray AS, Smidansky ED, Kireeva ML, Cho A, Perry J, Vela JE, Park Y, Xu Y, Tian Y, Babusis D, Barauskus O, Peterson BR, Gnatt A, Kashlev M, Zhong W, Cameron CE.

PLoS Pathog. 2012;8(11):e1003030. doi: 10.1371/journal.ppat.1003030. Epub 2012 Nov 15.

PMID:
23166498
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Nucleosomal elements that control the topography of the barrier to transcription.

Bintu L, Ishibashi T, Dangkulwanich M, Wu YY, Lubkowska L, Kashlev M, Bustamante C.

Cell. 2012 Nov 9;151(4):738-49. doi: 10.1016/j.cell.2012.10.009.

PMID:
23141536
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Co-transcriptional assembly of chemically modified RNA nanoparticles functionalized with siRNAs.

Afonin KA, Kireeva M, Grabow WW, Kashlev M, Jaeger L, Shapiro BA.

Nano Lett. 2012 Oct 10;12(10):5192-5. doi: 10.1021/nl302302e. Epub 2012 Sep 27.

PMID:
23016824
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase.

Kireeva ML, Opron K, Seibold SA, Domecq C, Cukier RI, Coulombe B, Kashlev M, Burton ZF.

BMC Biophys. 2012 Jun 7;5:11. doi: 10.1186/2046-1682-5-11.

PMID:
22676913
[PubMed]
Free PMC Article
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