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Results: 1 to 20 of 325

1.

Genetic Instability of Influenza pH1N1 Viruses.

Jalovaara P, Bychkov D, Ahtiainen L, Kallio-Kokko H, Valkonen M, Kantele A, Mattila P, Almusa H, Kallioniemi O, Kainov D.

Genome Announc. 2014 Oct 2;2(5). pii: e00841-14. doi: 10.1128/genomeA.00841-14.

PMID:
25278520
[PubMed]
Free PMC Article
2.

Identification of structural features in chemicals associated with cancer drug response: a systematic data-driven analysis.

Khan SA, Virtanen S, Kallioniemi OP, Wennerberg K, Poso A, Kaski S.

Bioinformatics. 2014 Sep 1;30(17):i497-504. doi: 10.1093/bioinformatics/btu456.

PMID:
25161239
[PubMed - in process]
Free PMC Article
3.

Integrative and personalized QSAR analysis in cancer by kernelized Bayesian matrix factorization.

Ammad-ud-din M, Georgii E, Gönen M, Laitinen T, Kallioniemi O, Wennerberg K, Poso A, Kaski S.

J Chem Inf Model. 2014 Aug 25;54(8):2347-59. doi: 10.1021/ci500152b. Epub 2014 Aug 6.

PMID:
25046554
[PubMed - in process]
4.

Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies.

Yadav B, Pemovska T, Szwajda A, Kulesskiy E, Kontro M, Karjalainen R, Majumder MM, Malani D, Murumägi A, Knowles J, Porkka K, Heckman C, Kallioniemi O, Wennerberg K, Aittokallio T.

Sci Rep. 2014 Jun 5;4:5193. doi: 10.1038/srep05193.

PMID:
24898935
[PubMed - in process]
Free PMC Article
5.

Functional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer.

Christensen LL, Holm A, Rantala J, Kallioniemi O, Rasmussen MH, Ostenfeld MS, Dagnaes-Hansen F, Øster B, Schepeler T, Tobiasen H, Thorsen K, Sieber OM, Gibbs P, Lamy P, Hansen TF, Jakobsen A, Riising EM, Helin K, Lubinski J, Hagemann-Madsen R, Laurberg S, Ørntoft TF, Andersen CL.

PLoS One. 2014 Jun 3;9(6):e96767. doi: 10.1371/journal.pone.0096767. eCollection 2014.

PMID:
24892549
[PubMed - in process]
Free PMC Article
6.

A community effort to assess and improve drug sensitivity prediction algorithms.

Costello JC, Heiser LM, Georgii E, Gönen M, Menden MP, Wang NJ, Bansal M, Ammad-Ud-Din M, Hintsanen P, Khan SA, Mpindi JP, Kallioniemi O, Honkela A, Aittokallio T, Wennerberg K; NCI DREAM Community, Collins JJ, Gallahan D, Singer D, Saez-Rodriguez J, Kaski S, Gray JW, Stolovitzky G; NCI DREAM Community.

Nat Biotechnol. 2014 Jun 1. doi: 10.1038/nbt.2877. [Epub ahead of print]

PMID:
24880487
[PubMed - as supplied by publisher]
7.

Akt inhibitor MK2206 prevents influenza pH1N1 virus infection in vitro.

Denisova OV, Söderholm S, Virtanen S, Von Schantz C, Bychkov D, Vashchinkina E, Desloovere J, Tynell J, Ikonen N, Theisen LL, Nyman TA, Matikainen S, Kallioniemi O, Julkunen I, Muller CP, Saelens X, Verkhusha VV, Kainov DE.

Antimicrob Agents Chemother. 2014 Jul;58(7):3689-96. doi: 10.1128/AAC.02798-13. Epub 2014 Apr 21.

PMID:
24752266
[PubMed - in process]
8.

A novel transcript, VNN1-AB, as a biomarker for colorectal cancer.

Løvf M, Nome T, Bruun J, Eknaes M, Bakken AC, Mpindi JP, Kilpinen S, Rognum TO, Nesbakken A, Kallioniemi O, Lothe RA, Skotheim RI.

Int J Cancer. 2014 Nov 1;135(9):2077-84. doi: 10.1002/ijc.28855. Epub 2014 Mar 29.

PMID:
24687856
[PubMed - indexed for MEDLINE]
9.

Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia.

Kontro M, Kuusanmäki H, Eldfors S, Burmeister T, Andersson EI, Bruserud O, Brümmendorf TH, Edgren H, Gjertsen BT, Itälä-Remes M, Lagström S, Lohi O, Lundán T, Martí JM, Majumder MM, Parsons A, Pemovska T, Rajala H, Vettenranta K, Kallioniemi O, Mustjoki S, Porkka K, Heckman CA.

Leukemia. 2014 Aug;28(8):1738-42. doi: 10.1038/leu.2014.89. Epub 2014 Feb 27. No abstract available.

PMID:
24573384
[PubMed - indexed for MEDLINE]
10.

Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells.

Pavet V, Shlyakhtina Y, He T, Ceschin DG, Kohonen P, Perälä M, Kallioniemi O, Gronemeyer H.

Cell Death Dis. 2014 Jan 30;5:e1043. doi: 10.1038/cddis.2014.5.

PMID:
24481457
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation.

Andersson EI, Rajala HL, Eldfors S, Ellonen P, Olson T, Jerez A, Clemente MJ, Kallioniemi O, Porkka K, Heckman C, Loughran TP Jr, Maciejewski JP, Mustjoki S.

Blood Cancer J. 2013 Dec 6;3:e168. doi: 10.1038/bcj.2013.65.

PMID:
24317090
[PubMed]
Free PMC Article
12.

Break-induced replication repair of damaged forks induces genomic duplications in human cells.

Costantino L, Sotiriou SK, Rantala JK, Magin S, Mladenov E, Helleday T, Haber JE, Iliakis G, Kallioniemi OP, Halazonetis TD.

Science. 2014 Jan 3;343(6166):88-91. doi: 10.1126/science.1243211. Epub 2013 Dec 5.

PMID:
24310611
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells.

Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M.

PLoS One. 2013 Oct 23;8(10):e77232. doi: 10.1371/journal.pone.0077232. eCollection 2013.

PMID:
24194875
[PubMed - in process]
Free PMC Article
14.

High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth.

Leivonen SK, Sahlberg KK, Mäkelä R, Due EU, Kallioniemi O, Børresen-Dale AL, Perälä M.

Mol Oncol. 2014 Feb;8(1):93-104. doi: 10.1016/j.molonc.2013.10.001. Epub 2013 Oct 11.

PMID:
24148764
[PubMed - indexed for MEDLINE]
15.

Plasticity of blood- and lymphatic endothelial cells and marker identification.

Keuschnigg J, Karinen S, Auvinen K, Irjala H, Mpindi JP, Kallioniemi O, Hautaniemi S, Jalkanen S, Salmi M.

PLoS One. 2013 Sep 10;8(9):e74293. doi: 10.1371/journal.pone.0074293. eCollection 2013. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/cfda269a-cb46-4735-b87f-42afccb6aeb1.

PMID:
24058540
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia.

Pemovska T, Kontro M, Yadav B, Edgren H, Eldfors S, Szwajda A, Almusa H, Bespalov MM, Ellonen P, Elonen E, Gjertsen BT, Karjalainen R, Kulesskiy E, Lagström S, Lehto A, Lepistö M, Lundán T, Majumder MM, Marti JM, Mattila P, Murumägi A, Mustjoki S, Palva A, Parsons A, Pirttinen T, Rämet ME, Suvela M, Turunen L, Västrik I, Wolf M, Knowles J, Aittokallio T, Heckman CA, Porkka K, Kallioniemi O, Wennerberg K.

Cancer Discov. 2013 Dec;3(12):1416-29. doi: 10.1158/2159-8290.CD-13-0350. Epub 2013 Sep 20.

PMID:
24056683
[PubMed - indexed for MEDLINE]
17.

Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis.

He T, Haapa-Paananen S, Kaminskyy VO, Kohonen P, Fey V, Zhivotovsky B, Kallioniemi O, Perälä M.

Oncogene. 2014 Jul 3;33(27):3538-49. doi: 10.1038/onc.2013.313. Epub 2013 Sep 9.

PMID:
24013224
[PubMed - indexed for MEDLINE]
18.

ARLTS1 and prostate cancer risk--analysis of expression and regulation.

Siltanen S, Fischer D, Rantapero T, Laitinen V, Mpindi JP, Kallioniemi O, Wahlfors T, Schleutker J.

PLoS One. 2013 Aug 5;8(8):e72040. doi: 10.1371/journal.pone.0072040. Print 2013.

PMID:
23940804
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Aneuploidy facilitates oncogenic transformation via specific genetic alterations, including Twist2 upregulation.

Högnäs G, Hämälistö S, Rilla K, Laine JO, Vilkki V, Murumägi A, Edgren H, Kallioniemi O, Ivaska J.

Carcinogenesis. 2013 Sep;34(9):2000-9. doi: 10.1093/carcin/bgt171. Epub 2013 May 20.

PMID:
23689353
[PubMed - indexed for MEDLINE]
Free Article
20.

Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia.

Rajala HL, Eldfors S, Kuusanmäki H, van Adrichem AJ, Olson T, Lagström S, Andersson EI, Jerez A, Clemente MJ, Yan Y, Zhang D, Awwad A, Ellonen P, Kallioniemi O, Wennerberg K, Porkka K, Maciejewski JP, Loughran TP Jr, Heckman C, Mustjoki S.

Blood. 2013 May 30;121(22):4541-50. doi: 10.1182/blood-2012-12-474577. Epub 2013 Apr 17.

PMID:
23596048
[PubMed - indexed for MEDLINE]
Free PMC Article

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