Kakui N[Author] - Search Results

Year	Number of Results
2004	2
2005	1
2006	1
2007	2
2009	3
2010	3
2024	0

1

Synthesis and structure-activity relationships of N-aryl-piperidine derivatives as potent (partial) agonists for human histamine H3 receptor.

Ishikawa M, Furuuchi T, Yamauchi M, Yokoyama F, Kakui N, Sato Y. Ishikawa M, et al. Among authors: kakui n. Bioorg Med Chem. 2010 Jul 15;18(14):5441-8. doi: 10.1016/j.bmc.2010.04.052. Epub 2010 Apr 21. Bioorg Med Chem. 2010. PMID: 20541426

2

EF6265, a novel inhibitor of activated thrombin-activatable fibrinolysis inhibitor, protects against sepsis-induced organ dysfunction in rats.

Muto Y, Suzuki K, Iida H, Sakakibara S, Kato E, Itoh F, Kakui N, Ishii H. Muto Y, et al. Among authors: kakui n. Crit Care Med. 2009 May;37(5):1744-9. doi: 10.1097/CCM.0b013e31819ffc14. Crit Care Med. 2009. PMID: 19325462

3

Anxiolytic-like profile of mirtazapine in rat conditioned fear stress model: Functional significance of 5-hydroxytryptamine 1A receptor and alpha1-adrenergic receptor.

Kakui N, Yokoyama F, Yamauchi M, Kitamura K, Imanishi T, Inoue T, Koyama T. Kakui N, et al. Pharmacol Biochem Behav. 2009 May;92(3):393-8. doi: 10.1016/j.pbb.2008.12.022. Epub 2009 Jan 11. Pharmacol Biochem Behav. 2009. PMID: 19167420

4

Anxiolytic-like profiles of histamine H3 receptor agonists in animal models of anxiety: a comparative study with antidepressants and benzodiazepine anxiolytic.

Yokoyama F, Yamauchi M, Oyama M, Okuma K, Onozawa K, Nagayama T, Shinei R, Ishikawa M, Sato Y, Kakui N. Yokoyama F, et al. Among authors: kakui n. Psychopharmacology (Berl). 2009 Aug;205(2):177-87. doi: 10.1007/s00213-009-1528-1. Epub 2009 Apr 9. Psychopharmacology (Berl). 2009. PMID: 19357839

5

A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats.

Nakajima H, Kakui N, Ohkuma K, Ishikawa M, Hasegawa T. Nakajima H, et al. Among authors: kakui n. J Pharmacol Exp Ther. 2005 Feb;312(2):472-81. doi: 10.1124/jpet.104.075465. Epub 2004 Oct 1. J Pharmacol Exp Ther. 2005. PMID: 15466246

6

Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active histamine type 3 receptor agonist and evaluation of its antistress activity in mice.

Ishikawa M, Shinei R, Yokoyama F, Yamauchi M, Oyama M, Okuma K, Nagayama T, Kato K, Kakui N, Sato Y. Ishikawa M, et al. Among authors: kakui n. J Med Chem. 2010 May 13;53(9):3840-4. doi: 10.1021/jm901890s. J Med Chem. 2010. PMID: 20384344

7

Investigation of the histamine H3 receptor binding site. Design and synthesis of hybrid agonists with a lipophilic side chain.

Ishikawa M, Watanabe T, Kudo T, Yokoyama F, Yamauchi M, Kato K, Kakui N, Sato Y. Ishikawa M, et al. Among authors: kakui n. J Med Chem. 2010 Sep 9;53(17):6445-56. doi: 10.1021/jm100643t. J Med Chem. 2010. PMID: 20690643

8

The selective serotonin reuptake inhibitor fluvoxamine suppresses post-feeding hyperactivity induced by food restriction in rats.

Yokoyama F, Onozawa K, Kakui N, Imanishi T. Yokoyama F, et al. Among authors: kakui n. Pharmacol Biochem Behav. 2007 May;87(1):98-103. doi: 10.1016/j.pbb.2007.04.004. Epub 2007 Apr 11. Pharmacol Biochem Behav. 2007. PMID: 17493672

9

Critical role of the automodification of poly(ADP-ribose) polymerase-1 in nuclear factor-kappaB-dependent gene expression in primary cultured mouse glial cells.

Nakajima H, Nagaso H, Kakui N, Ishikawa M, Hiranuma T, Hoshiko S. Nakajima H, et al. Among authors: kakui n. J Biol Chem. 2004 Oct 8;279(41):42774-86. doi: 10.1074/jbc.M407923200. Epub 2004 Aug 9. J Biol Chem. 2004. PMID: 15302869 Free article.

10

Pharmacological characterization and feeding-suppressive property of FMS586 [3-(5,6,7,8-tetrahydro-9-isopropyl-carbazol-3-yl)-1-methyl-1-(2-pyridin-4-yl-ethyl)-urea hydrochloride], a novel, selective, and orally active antagonist for neuropeptide Y Y5 receptor.

Kakui N, Tanaka J, Tabata Y, Asai K, Masuda N, Miyara T, Nakatani Y, Ohsawa F, Nishikawa N, Sugai M, Suzuki M, Aoki K, Kitaguchi H. Kakui N, et al. J Pharmacol Exp Ther. 2006 May;317(2):562-70. doi: 10.1124/jpet.105.099705. Epub 2006 Jan 25. J Pharmacol Exp Ther. 2006. PMID: 16436501

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