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Results: 1 to 20 of 39

1.

Genetic control of differential acetylation in diabetic rats.

Kaisaki PJ, Otto GW, McGouran JF, Toubal A, Argoud K, Waller-Evans H, Finlay C, Caldérari S, Bihoreau MT, Kessler BM, Gauguier D, Mott R.

PLoS One. 2014 Apr 17;9(4):e94555. doi: 10.1371/journal.pone.0094555. eCollection 2014.

PMID:
24743600
[PubMed - in process]
Free PMC Article
2.

Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat.

Atanur SS, Diaz AG, Maratou K, Sarkis A, Rotival M, Game L, Tschannen MR, Kaisaki PJ, Otto GW, Ma MC, Keane TM, Hummel O, Saar K, Chen W, Guryev V, Gopalakrishnan K, Garrett MR, Joe B, Citterio L, Bianchi G, McBride M, Dominiczak A, Adams DJ, Serikawa T, Flicek P, Cuppen E, Hubner N, Petretto E, Gauguier D, Kwitek A, Jacob H, Aitman TJ.

Cell. 2013 Aug 1;154(3):691-703. doi: 10.1016/j.cell.2013.06.040. Epub 2013 Jul 25.

PMID:
23890820
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Untargeted metabolome quantitative trait locus mapping associates variation in urine glycerate to mutant glycerate kinase.

Cazier JB, Kaisaki PJ, Argoud K, Blaise BJ, Veselkov K, Ebbels TM, Tsang T, Wang Y, Bihoreau MT, Mitchell SC, Holmes EC, Lindon JC, Scott J, Nicholson JK, Dumas ME, Gauguier D.

J Proteome Res. 2012 Feb 3;11(2):631-42. doi: 10.1021/pr200566t. Epub 2011 Nov 28.

PMID:
22029865
[PubMed - indexed for MEDLINE]
4.

Broad-ranging natural metabotype variation drives physiological plasticity in healthy control inbred rat strains.

Pontoizeau C, Fearnside JF, Navratil V, Domange C, Cazier JB, Fernández-Santamaría C, Kaisaki PJ, Emsley L, Toulhoat P, Bihoreau MT, Nicholson JK, Gauguier D, Dumas ME.

J Proteome Res. 2011 Apr 1;10(4):1675-89. doi: 10.1021/pr101000z. Epub 2011 Mar 15.

PMID:
21322573
[PubMed - indexed for MEDLINE]
5.

Chromosomal mapping of pancreatic islet morphological features and regulatory hormones in the spontaneously diabetic (Type 2) Goto-Kakizaki rat.

Finlay C, Argoud K, Wilder SP, Ouali F, Ktorza A, Kaisaki PJ, Gauguier D.

Mamm Genome. 2010 Oct;21(9-10):499-508. doi: 10.1007/s00335-010-9285-3. Epub 2010 Sep 29.

PMID:
20878524
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes.

Herrera BM, Lockstone HE, Taylor JM, Wills QF, Kaisaki PJ, Barrett A, Camps C, Fernandez C, Ragoussis J, Gauguier D, McCarthy MI, Lindgren CM.

BMC Med Genomics. 2009 Aug 18;2:54. doi: 10.1186/1755-8794-2-54.

PMID:
19689793
[PubMed]
Free PMC Article
7.

Functional annotations of diabetes nephropathy susceptibility loci through analysis of genome-wide renal gene expression in rat models of diabetes mellitus.

Hu Y, Kaisaki PJ, Argoud K, Wilder SP, Wallace KJ, Woon PY, Blancher C, Tarnow L, Groop PH, Hadjadj S, Marre M, Parving HH, Farrall M, Cox RD, Lathrop M, Vionnet N, Bihoreau MT, Gauguier D.

BMC Med Genomics. 2009 Jul 9;2:41. doi: 10.1186/1755-8794-2-41.

PMID:
19586551
[PubMed]
Free PMC Article
8.

Comparative analysis of methods for gene transcription profiling data derived from different microarray technologies in rat and mouse models of diabetes.

Wilder SP, Kaisaki PJ, Argoud K, Salhan A, Ragoussis J, Bihoreau MT, Gauguier D.

BMC Genomics. 2009 Feb 5;10:63. doi: 10.1186/1471-2164-10-63.

PMID:
19196459
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Pathophysiological, genetic and gene expression features of a novel rodent model of the cardio-metabolic syndrome.

Wallis RH, Collins SC, Kaisaki PJ, Argoud K, Wilder SP, Wallace KJ, Ria M, Ktorza A, Rorsman P, Bihoreau MT, Gauguier D.

PLoS One. 2008 Aug 13;3(8):e2962. doi: 10.1371/journal.pone.0002962.

PMID:
18698428
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Genomic organization and mutation screening of the human ortholog of Pkdr1 associated with polycystic kidney disease in the rat.

Kaisaki PJ, Bergmann C, Brown JH, Outeda P, Lens XM, Peters DJ, Gretz N, Gauguier D, Bihoreau MT.

Eur J Med Genet. 2008 Jul-Aug;51(4):325-31. doi: 10.1016/j.ejmg.2008.02.007. Epub 2008 Mar 16.

PMID:
18434273
[PubMed - indexed for MEDLINE]
11.

Aryl hydrocarbon receptor nuclear translocator-like (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes.

Woon PY, Kaisaki PJ, Bragança J, Bihoreau MT, Levy JC, Farrall M, Gauguier D.

Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14412-7. Epub 2007 Aug 29.

PMID:
17728404
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension.

Marçano AC, Burke B, Gungadoo J, Wallace C, Kaisaki PJ, Woon PY, Farrall M, Clayton D, Brown M, Dominiczak A, Connell JM, Webster J, Lathrop M, Caulfield M, Samani N, Gauguier D, Munroe PB.

J Med Genet. 2007 Sep;44(9):603-5. Epub 2007 Jun 8.

PMID:
17557929
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Mapping diabetes QTL in an intercross derived from a congenic strain of the Brown Norway and Goto-Kakizaki rats.

Collins SC, Wallis RH, Wilder SP, Wallace KJ, Argoud K, Kaisaki PJ, Bihoreau MT, Gauguier D.

Mamm Genome. 2006 Jun;17(6):538-47. Epub 2006 Jun 12.

PMID:
16783636
[PubMed - indexed for MEDLINE]
14.

Genomic organization of the rat Clock gene and sequence analysis in inbred rat strains.

Woon PY, Curtis AM, Kaisaki PJ, Argoud K, Wallace KJ, Bihoreau MT, FitzGerald GA, Gauguier D.

Genomics. 2006 Feb;87(2):208-17. Epub 2006 Jan 11.

PMID:
16376516
[PubMed - indexed for MEDLINE]
Free Article
15.

Missense mutation in sterile alpha motif of novel protein SamCystin is associated with polycystic kidney disease in (cy/+) rat.

Brown JH, Bihoreau MT, Hoffmann S, Kränzlin B, Tychinskaya I, Obermüller N, Podlich D, Boehn SN, Kaisaki PJ, Megel N, Danoy P, Copley RR, Broxholme J, Witzgall R, Lathrop M, Gretz N, Gauguier D.

J Am Soc Nephrol. 2005 Dec;16(12):3517-26. Epub 2005 Oct 5.

PMID:
16207829
[PubMed - indexed for MEDLINE]
Free Article
16.

Medical Genetics: revenge of the thrift.

Kaisaki PJ, Gauguier D.

Heredity (Edinb). 2005 Nov;95(5):337-8. No abstract available.

PMID:
15999140
[PubMed - indexed for MEDLINE]
Free Article
17.

Quantitative trait locus dissection in congenic strains of the Goto-Kakizaki rat identifies a region conserved with diabetes loci in human chromosome 1q.

Wallace KJ, Wallis RH, Collins SC, Argoud K, Kaisaki PJ, Ktorza A, Woon PY, Bihoreau MT, Gauguier D.

Physiol Genomics. 2004 Sep 16;19(1):1-10. Epub 2004 Jul 20.

PMID:
15266047
[PubMed - indexed for MEDLINE]
Free Article
18.

Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndrome.

Kaisaki PJ, Delépine M, Woon PY, Sebag-Montefiore L, Wilder SP, Menzel S, Vionnet N, Marion E, Riveline JP, Charpentier G, Schurmans S, Levy JC, Lathrop M, Farrall M, Gauguier D.

Diabetes. 2004 Jul;53(7):1900-4.

PMID:
15220217
[PubMed - indexed for MEDLINE]
Free Article
19.

Enhanced insulin secretion and cholesterol metabolism in congenic strains of the spontaneously diabetic (Type 2) Goto Kakizaki rat are controlled by independent genetic loci in rat chromosome 8.

Wallis RH, Wallace KJ, Collins SC, McAteer M, Argoud K, Bihoreau MT, Kaisaki PJ, Gauguier D.

Diabetologia. 2004 Jun;47(6):1096-106. Epub 2004 May 26.

PMID:
15164172
[PubMed - indexed for MEDLINE]
20.

Localization, cDNA sequence and genomic organization of the rat seipin gene (Bscl2) and sequence analysis in inbred rat models of Type 2 diabetes mellitus.

Kaisaki PJ, Sebag-Montefiore LM, Brown JH, Magre J, Lathrop M, Capeau J, Gauguier D.

Cytogenet Genome Res. 2002;98(1):71-4.

PMID:
12584444
[PubMed - indexed for MEDLINE]

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