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Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.

Mengelbier LH, Karlsson J, Lindgren D, Valind A, Lilljebjörn H, Jansson C, Bexell D, Braekeveldt N, Ameur A, Jonson T, Kultima HG, Isaksson A, Asmundsson J, Versteeg R, Rissler M, Fioretos T, Sandstedt B, Börjesson A, Backman T, Pal N, Øra I, Mayrhofer M, Gisselsson D.

Nat Commun. 2015 Jan 27;6:6125. doi: 10.1038/ncomms7125.


Neuroblastoma patient-derived orthotopic xenografts retain metastatic patterns and geno- and phenotypes of patient tumours.

Braekeveldt N, Wigerup C, Gisselsson D, Mohlin S, Merselius M, Beckman S, Jonson T, Börjesson A, Backman T, Tadeo I, Berbegall AP, Ora I, Navarro S, Noguera R, Påhlman S, Bexell D.

Int J Cancer. 2015 Mar 1;136(5):E252-61. doi: 10.1002/ijc.29217. Epub 2014 Oct 7.


Oral rivaroxaban for the treatment of symptomatic pulmonary embolism.

EINSTEIN–PE Investigators, Büller HR, Prins MH, Lensin AW, Decousus H, Jacobson BF, Minar E, Chlumsky J, Verhamme P, Wells P, Agnelli G, Cohen A, Berkowitz SD, Bounameaux H, Davidson BL, Misselwitz F, Gallus AS, Raskob GE, Schellong S, Segers A.

N Engl J Med. 2012 Apr 5;366(14):1287-97. doi: 10.1056/NEJMoa1113572. Epub 2012 Mar 26.


Oral rivaroxaban for symptomatic venous thromboembolism.

EINSTEIN Investigators, Bauersachs R, Berkowitz SD, Brenner B, Buller HR, Decousus H, Gallus AS, Lensing AW, Misselwitz F, Prins MH, Raskob GE, Segers A, Verhamme P, Wells P, Agnelli G, Bounameaux H, Cohen A, Davidson BL, Piovella F, Schellong S.

N Engl J Med. 2010 Dec 23;363(26):2499-510. doi: 10.1056/NEJMoa1007903. Epub 2010 Dec 3.


Telomeric associations correlate with telomere length reduction and clonal chromosome aberrations in giant cell tumor of bone.

Gebre-Medhin S, Broberg K, Jonson T, Gorunova L, von Steyern FV, Brosjö O, Jin Y, Gisselsson D, Panagopoulos I, Mandahl N, Mertens F.

Cytogenet Genome Res. 2009;124(2):121-7. doi: 10.1159/000207516. Epub 2009 May 5.


Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis.

Rossebø AB, Pedersen TR, Boman K, Brudi P, Chambers JB, Egstrup K, Gerdts E, Gohlke-Bärwolf C, Holme I, Kesäniemi YA, Malbecq W, Nienaber CA, Ray S, Skjaerpe T, Wachtell K, Willenheimer R; SEAS Investigators.

N Engl J Med. 2008 Sep 25;359(13):1343-56. doi: 10.1056/NEJMoa0804602. Epub 2008 Sep 2.


Efficacy and safety of the oral direct factor Xa inhibitor apixaban for symptomatic deep vein thrombosis. The Botticelli DVT dose-ranging study.

Botticelli Investigators, Writing Committe, Buller H, Deitchman D, Prins M, Segers A.

J Thromb Haemost. 2008 Aug;6(8):1313-8. doi: 10.1111/j.1538-7836.2008.03054.x. Epub 2008 Jun 6.


Tiling resolution array CGH and high density expression profiling of urothelial carcinomas delineate genomic amplicons and candidate target genes specific for advanced tumors.

Heidenblad M, Lindgren D, Jonson T, Liedberg F, Veerla S, Chebil G, Gudjonsson S, Borg A, Månsson W, Höglund M.

BMC Med Genomics. 2008 Jan 31;1:3. doi: 10.1186/1755-8794-1-3.


Distinct mitotic segregation errors mediate chromosomal instability in aggressive urothelial cancers.

Jin Y, Stewénius Y, Lindgren D, Frigyesi A, Calcagnile O, Jonson T, Edqvist A, Larsson N, Lundberg LM, Chebil G, Liedberg F, Gudjonsson S, Månsson W, Höglund M, Gisselsson D.

Clin Cancer Res. 2007 Mar 15;13(6):1703-12.


Long-term exposure to urban air pollution and myocardial infarction.

Rosenlund M, Berglind N, Pershagen G, Hallqvist J, Jonson T, Bellander T.

Epidemiology. 2006 Jul;17(4):383-90.


Structural and numerical chromosome changes in colon cancer develop through telomere-mediated anaphase bridges, not through mitotic multipolarity.

Stewénius Y, Gorunova L, Jonson T, Larsson N, Höglund M, Mandahl N, Mertens F, Mitelman F, Gisselsson D.

Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5541-6. Epub 2005 Apr 4.


Microarray analyses reveal strong influence of DNA copy number alterations on the transcriptional patterns in pancreatic cancer: implications for the interpretation of genomic amplifications.

Heidenblad M, Lindgren D, Veltman JA, Jonson T, Mahlamäki EH, Gorunova L, van Kessel AG, Schoenmakers EF, Höglund M.

Oncogene. 2005 Mar 3;24(10):1794-801.


A new CT method for measuring cup orientation after total hip arthroplasty: a study of 10 patients.

Olivecrona H, Weidenhielm L, Olivecrona L, Beckman MO, Stark A, Noz ME, Maguire GQ Jr, Zeleznik MP, Svensson L, Jonson T.

Acta Orthop Scand. 2004 Jun;75(3):252-60.


Retained heterodisomy for chromosome 12 in atypical lipomatous tumors: implications for ring chromosome formation.

Mertens F, Panagopoulos I, Jonson T, Gisselsson D, Isaksson M, Domanski HA, Mandahl N.

Cytogenet Genome Res. 2004;106(1):33-8.


Genome-wide array-based comparative genomic hybridization reveals multiple amplification targets and novel homozygous deletions in pancreatic carcinoma cell lines.

Heidenblad M, Schoenmakers EF, Jonson T, Gorunova L, Veltman JA, van Kessel AG, Höglund M.

Cancer Res. 2004 May 1;64(9):3052-9.


Stability of acetabular axis after total hip arthroplasty, repeatability using CT and a semiautomated program for volume fusion.

Olivecrona H, Olivecrona L, Weidenhielm L, Noz ME, Maguire GQ, Zeleznik MP, Svensson L, Jonson T.

Acta Radiol. 2003 Nov;44(6):653-61.


Spatial component position in total hip arthroplasty. Accuracy and repeatability with a new CT method.

Olivecrona H, Weidenhielm L, Olivecrona L, Noz ME, Maguire GQ Jr, Zeleznik MP, Svensson L, Jonson T.

Acta Radiol. 2003 Jan;44(1):84-91.


Pancreatic carcinoma cell lines with SMAD4 inactivation show distinct expression responses to TGFB1.

Jonson T, Heidenblad M, Håkansson P, Gorunova L, Johansson B, Fioretos T, Höglund M.

Genes Chromosomes Cancer. 2003 Apr;36(4):340-52.


Centrosomal abnormalities, multipolar mitoses, and chromosomal instability in head and neck tumours with dysfunctional telomeres.

Gisselsson D, Jonson T, Yu C, Martins C, Mandahl N, Wiegant J, Jin Y, Mertens F, Jin C.

Br J Cancer. 2002 Jul 15;87(2):202-7.

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