PubMed

Effects of HIV type-1 immune selection on susceptability to integrase inhibitor resistance.

Tschochner M, Chopra A, Maiden TM, Ahmad IF, James I, Furrer H, Günthard HF, Mallal S, Rauch A, John M.

Antivir Ther. 2009;14(7):953-64.PMID: 19918099 [PubMed - in process]Related articles

HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins.

Brumme ZL, John M, Carlson JM, Brumme CJ, Chan D, Brockman MA, Swenson LC, Tao I, Szeto S, Rosato P, Sela J, Kadie CM, Frahm N, Brander C, Haas DW, Riddler SA, Haubrich R, Walker BD, Harrigan PR, Heckerman D, Mallal S.

PLoS One. 2009 Aug 19;4(8):e6687.PMID: 19690614 [PubMed - in process]Related articlesFree article

Divergent adaptation of hepatitis C virus genotypes 1 and 3 to human leukocyte antigen-restricted immune pressure.

Rauch A, James I, Pfafferott K, Nolan D, Klenerman P, Cheng W, Mollison L, McCaughan G, Shackel N, Jeffrey GP, Baker R, Freitas E, Humphreys I, Furrer H, Günthard HF, Hirschel B, Mallal S, John M, Lucas M, Barnes E, Gaudieri S.

Hepatology. 2009 Oct;50(4):1017-29.PMID: 19670417 [PubMed - indexed for MEDLINE]Related articles

Unique features of HLA-mediated HIV evolution in a Mexican cohort: a comparative study.

Avila-Rios S, Ormsby CE, Carlson JM, Valenzuela-Ponce H, Blanco-Heredia J, Garrido-Rodriguez D, Garcia-Morales C, Heckerman D, Brumme ZL, Mallal S, John M, Espinosa E, Reyes-Teran G.

Retrovirology. 2009 Aug 10;6:72.PMID: 19664284 [PubMed - indexed for MEDLINE]Related articlesFree article

The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target.

Mina JG, Pan SY, Wansadhipathi NK, Bruce CR, Shams-Eldin H, Schwarz RT, Steel PG, Denny PW.

Mol Biochem Parasitol. 2009 Nov;168(1):16-23. Epub 2009 Jun 21.PMID: 19545591 [PubMed - indexed for MEDLINE]Related articles

Automation of the ELISpot assay for high-throughput detection of antigen-specific T-cell responses.

Almeida CA, Roberts SG, Laird R, McKinnon E, Ahmed I, Pfafferott K, Turley J, Keane NM, Lucas A, Rushton B, Chopra A, Mallal S, John M.

J Immunol Methods. 2009 May 15;344(1):1-5. Epub 2009 Mar 10.PMID: 19285081 [PubMed - indexed for MEDLINE]Related articles

Adaptation of HIV-1 to human leukocyte antigen class I.

Kawashima Y, Pfafferott K, Frater J, Matthews P, Payne R, Addo M, Gatanaga H, Fujiwara M, Hachiya A, Koizumi H, Kuse N, Oka S, Duda A, Prendergast A, Crawford H, Leslie A, Brumme Z, Brumme C, Allen T, Brander C, Kaslow R, Tang J, Hunter E, Allen S, Mulenga J, Branch S, Roach T, John M, Mallal S, Ogwu A, Shapiro R, Prado JG, Fidler S, Weber J, Pybus OG, Klenerman P, Ndung'u T, Phillips R, Heckerman D, Harrigan PR, Walker BD, Takiguchi M, Goulder P.

Nature. 2009 Apr 2;458(7238):641-5. Epub 2009 Feb 25.PMID: 19242411 [PubMed - indexed for MEDLINE]Related articles

HLA-associated viral mutations are common in human immunodeficiency virus type 1 elite controllers.

Miura T, Brumme CJ, Brockman MA, Brumme ZL, Pereyra F, Block BL, Trocha A, John M, Mallal S, Harrigan PR, Walker BD.

J Virol. 2009 Apr;83(7):3407-12. Epub 2009 Jan 19.PMID: 19153230 [PubMed - indexed for MEDLINE]Related articlesFree article

Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection.

Brumme ZL, Brumme CJ, Carlson J, Streeck H, John M, Eichbaum Q, Block BL, Baker B, Kadie C, Markowitz M, Jessen H, Kelleher AD, Rosenberg E, Kaldor J, Yuki Y, Carrington M, Allen TM, Mallal S, Altfeld M, Heckerman D, Walker BD.

J Virol. 2008 Sep;82(18):9216-27. Epub 2008 Jul 9.PMID: 18614631 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA-Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy.

Rauch A, Nolan D, Furrer H, McKinnon E, John M, Mallal S, Gaudieri S, Günthard HF, Schmid P, Battegay M, Hirschel B, Telenti A, James I; Swiss HIV Cohort Study.

Clin Infect Dis. 2008 Jun 15;46(12):1921-5.PMID: 18466093 [PubMed - indexed for MEDLINE]Related articles

Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype.

Harari A, Cellerai C, Enders FB, Köstler J, Codarri L, Tapia G, Boyman O, Castro E, Gaudieri S, James I, John M, Wagner R, Mallal S, Pantaleo G.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16233-8. Epub 2007 Oct 2.PMID: 17911249 [PubMed - indexed for MEDLINE]Related articlesFree article

Extensive HLA class I allele promiscuity among viral CTL epitopes.

Frahm N, Yusim K, Suscovich TJ, Adams S, Sidney J, Hraber P, Hewitt HS, Linde CH, Kavanagh DG, Woodberry T, Henry LM, Faircloth K, Listgarten J, Kadie C, Jojic N, Sango K, Brown NV, Pae E, Zaman MT, Bihl F, Khatri A, John M, Mallal S, Marincola FM, Walker BD, Sette A, Heckerman D, Korber BT, Brander C.

Eur J Immunol. 2007 Sep;37(9):2419-33.PMID: 17705138 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses.

Bihl F, Frahm N, Di Giammarino L, Sidney J, John M, Yusim K, Woodberry T, Sango K, Hewitt HS, Henry L, Linde CH, Chisholm JV 3rd, Zaman TM, Pae E, Mallal S, Walker BD, Sette A, Korber BT, Heckerman D, Brander C.

J Immunol. 2006 Apr 1;176(7):4094-101.PMID: 16547245 [PubMed - indexed for MEDLINE]Related articlesFree article

De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection.

Allen TM, Yu XG, Kalife ET, Reyor LL, Lichterfeld M, John M, Cheng M, Allgaier RL, Mui S, Frahm N, Alter G, Brown NV, Johnston MN, Rosenberg ES, Mallal SA, Brander C, Walker BD, Altfeld M.

J Virol. 2005 Oct;79(20):12952-60.PMID: 16188997 [PubMed - indexed for MEDLINE]Related articlesFree article

Interactive selective pressures of HLA-restricted immune responses and antiretroviral drugs on HIV-1.

John M, Moore CB, James IR, Mallal SA.

Antivir Ther. 2005;10(4):551-5.PMID: 16038481 [PubMed - indexed for MEDLINE]Related articles

CTL responses to HIV and SIV: wrestling with smoke.

John M, Mallal S.

Nat Immunol. 2005 Mar;6(3):232-4. No abstract available. PMID: 15716970 [PubMed - indexed for MEDLINE]Related articles

Impact of host genetics on HIV disease progression and treatment: new conflicts on an ancient battleground.

Nolan D, Gaudieri S, John M, Mallal S.

AIDS. 2004 Jun 18;18(9):1231-40. Review. No abstract available. PMID: 15362655 [PubMed - indexed for MEDLINE]Related articles

Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection.

Allen TM, Altfeld M, Yu XG, O'Sullivan KM, Lichterfeld M, Le Gall S, John M, Mothe BR, Lee PK, Kalife ET, Cohen DE, Freedberg KA, Strick DA, Johnston MN, Sette A, Rosenberg ES, Mallal SA, Goulder PJ, Brander C, Walker BD.

J Virol. 2004 Jul;78(13):7069-78.PMID: 15194783 [PubMed - indexed for MEDLINE]Related articlesFree article

Randomized, controlled, 48-week study of switching stavudine and/or protease inhibitors to combivir/abacavir to prevent or reverse lipoatrophy in HIV-infected patients.

John M, McKinnon EJ, James IR, Nolan DA, Herrmann SE, Moore CB, White AJ, Mallal SA.

J Acquir Immune Defic Syndr. 2003 May 1;33(1):29-33.PMID: 12792352 [PubMed - indexed for MEDLINE]Related articles

Viral load detectability profiles for HIV infection.

McKinnon EJ, James IR, John M, Mallal SA.

Stat Med. 2003 Feb 15;22(3):385-96.PMID: 12529870 [PubMed - indexed for MEDLINE]Related articles