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Results: 5


Genomic instability causes HGF gene activation in colon cancer cells, promoting their resistance to necroptosis.

Seneviratne D, Ma J, Tan X, Kwon YK, Muhammad E, Melhem M, DeFrances MC, Zarnegar R.

Gastroenterology. 2015 Jan;148(1):181-191.e17. doi: 10.1053/j.gastro.2014.09.019. Epub 2014 Sep 20.


Novel Death Defying Domain in Met entraps the active site of caspase-3 and blocks apoptosis in hepatocytes.

Ma J, Zou C, Guo L, Seneviratne DS, Tan X, Kwon YK, An J, Bowser R, DeFrances MC, Zarnegar R.

Hepatology. 2014 May;59(5):2010-21. doi: 10.1002/hep.26769. Epub 2014 Apr 1.


A hepatocyte growth factor receptor (Met)-insulin receptor hybrid governs hepatic glucose metabolism.

Fafalios A, Ma J, Tan X, Stoops J, Luo J, Defrances MC, Zarnegar R.

Nat Med. 2011 Nov 13;17(12):1577-84. doi: 10.1038/nm.2531.


Somatic mutation and functional polymorphism of a novel regulatory element in the HGF gene promoter causes its aberrant expression in human breast cancer.

Ma J, DeFrances MC, Zou C, Johnson C, Ferrell R, Zarnegar R.

J Clin Invest. 2009 Mar;119(3):478-91. doi: 10.1172/JCI36640. Epub 2009 Feb 2.


Lack of Fas antagonism by Met in human fatty liver disease.

Zou C, Ma J, Wang X, Guo L, Zhu Z, Stoops J, Eaker AE, Johnson CJ, Strom S, Michalopoulos GK, DeFrances MC, Zarnegar R.

Nat Med. 2007 Sep;13(9):1078-85. Epub 2007 Aug 19.

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