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Mechanistic and Structural Analysis of a Drosophila melanogaster Enzyme, Arylalkylamine N-Acetyltransferase Like 7, an Enzyme That Catalyzes the Formation of N-Acetylarylalkylamides and N-Acetylhistamine.

Dempsey DR, Jeffries KA, Handa S, Carpenter AM, Rodriguez-Ospina S, Breydo L, Merkler DJ.

Biochemistry. 2015 Apr 28;54(16):2644-58. doi: 10.1021/acs.biochem.5b00113. Epub 2015 Apr 16.


Chronic exposures to low and high concentrations of ibuprofen elicit different gene response patterns in a euryhaline fish.

Jeffries KM, Brander SM, Britton MT, Fangue NA, Connon RE.

Environ Sci Pollut Res Int. 2015 Mar 4. [Epub ahead of print]


Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase.

Mishra A, Brown AL, Yao X, Yang S, Park SJ, Liu C, Dagur PK, McCoy JP, Keeran KJ, Nugent GZ, Jeffries KR, Qu X, Yu ZX, Levine SJ, Chung JH.

Nat Commun. 2015 Feb 18;6:6224. doi: 10.1038/ncomms7224.


Mechanistic and structural analysis of Drosophila melanogaster arylalkylamine N-acetyltransferases.

Dempsey DR, Jeffries KA, Bond JD, Carpenter AM, Rodriguez-Ospina S, Breydo L, Caswell KK, Merkler DJ.

Biochemistry. 2014 Dec 16;53(49):7777-93. doi: 10.1021/bi5006078. Epub 2014 Dec 1.


Immune response genes and pathogen presence predict migration survival in wild salmon smolts.

Jeffries KM, Hinch SG, Gale MK, Clark TD, Lotto AG, Casselman MT, Li S, Rechisky EL, Porter AD, Welch DW, Miller KM.

Mol Ecol. 2014 Dec;23(23):5803-15. doi: 10.1111/mec.12980. Epub 2014 Nov 21.


Using CD4 percentage and age to optimize pediatric antiretroviral therapy initiation.

Yin DE, Warshaw MG, Miller WC, Castro H, Fiscus SA, Harper LM, Harrison LJ, Klein NJ, Lewis J, Melvin AJ, Tudor-Williams G, McKinney RE Jr; PENPACT-1 (PENTA 9/PACTG 390) Study Team.

Pediatrics. 2014 Oct;134(4):e1104-16. doi: 10.1542/peds.2014-0527.


Drosophila melanogaster as a model system to study long-chain fatty acid amide metabolism.

Jeffries KA, Dempsey DR, Behari AL, Anderson RL, Merkler DJ.

FEBS Lett. 2014 May 2;588(9):1596-602. doi: 10.1016/j.febslet.2014.02.051. Epub 2014 Mar 17.


Species- and sex-specific responses and recovery of wild, mature pacific salmon to an exhaustive exercise and air exposure stressor.

Donaldson MR, Hinch SG, Jeffries KM, Patterson DA, Cooke SJ, Farrell AP, Miller KM.

Comp Biochem Physiol A Mol Integr Physiol. 2014 Mar 4;173C:7-16. doi: 10.1016/j.cbpa.2014.02.019. [Epub ahead of print]


Transcriptomic responses to high water temperature in two species of Pacific salmon.

Jeffries KM, Hinch SG, Sierocinski T, Pavlidis P, Miller KM.

Evol Appl. 2014 Feb;7(2):286-300. doi: 10.1111/eva.12119. Epub 2013 Nov 12.


Identification of an arylalkylamine N-acyltransferase from Drosophila melanogaster that catalyzes the formation of long-chain N-acylserotonins.

Dempsey DR, Jeffries KA, Anderson RL, Carpenter AM, Rodriquez Opsina S, Merkler DJ.

FEBS Lett. 2014 Feb 14;588(4):594-9. doi: 10.1016/j.febslet.2013.12.027. Epub 2014 Jan 18.


Consequences of high temperatures and premature mortality on the transcriptome and blood physiology of wild adult sockeye salmon (Oncorhynchus nerka).

Jeffries KM, Hinch SG, Sierocinski T, Clark TD, Eliason EJ, Donaldson MR, Li S, Pavlidis P, Miller KM.

Ecol Evol. 2012 Jul;2(7):1747-64. doi: 10.1002/ece3.274.


Conservation physiology in practice: how physiological knowledge has improved our ability to sustainably manage Pacific salmon during up-river migration.

Cooke SJ, Hinch SG, Donaldson MR, Clark TD, Eliason EJ, Crossin GT, Raby GD, Jeffries KM, Lapointe M, Miller K, Patterson DA, Farrell AP.

Philos Trans R Soc Lond B Biol Sci. 2012 Jun 19;367(1596):1757-69. doi: 10.1098/rstb.2012.0022. Review.


Coronary artery wall imaging in mice using osmium tetroxide and micro-computed tomography (micro-CT).

Pai VM, Kozlowski M, Donahue D, Miller E, Xiao X, Chen MY, Yu ZX, Connelly P, Jeffries K, Wen H.

J Anat. 2012 May;220(5):514-24. doi: 10.1111/j.1469-7580.2012.01483.x. Epub 2012 Feb 23.


Sex and proximity to reproductive maturity influence the survival, final maturation, and blood physiology of Pacific salmon when exposed to high temperature during a simulated migration.

Jeffries KM, Hinch SG, Martins EG, Clark TD, Lotto AG, Patterson DA, Cooke SJ, Farrell AP, Miller KM.

Physiol Biochem Zool. 2012 Jan-Feb;85(1):62-73. doi: 10.1086/663770. Epub 2011 Dec 15.


Primary fatty acid amide metabolism: conversion of fatty acids and an ethanolamine in N18TG2 and SCP cells.

Farrell EK, Chen Y, Barazanji M, Jeffries KA, Cameroamortegui F, Merkler DJ.

J Lipid Res. 2012 Feb;53(2):247-56. doi: 10.1194/jlr.M018606. Epub 2011 Nov 16.


Exceptional aerobic scope and cardiovascular performance of pink salmon (Oncorhynchus gorbuscha) may underlie resilience in a warming climate.

Clark TD, Jeffries KM, Hinch SG, Farrell AP.

J Exp Biol. 2011 Sep 15;214(Pt 18):3074-81. doi: 10.1242/jeb.060517.


Temporal changes in blood variables during final maturation and senescence in male sockeye salmon Oncorhynchus nerka: reduced osmoregulatory ability can predict mortality.

Jeffries KM, Hinch SG, Donaldson MR, Gale MK, Burt JM, Thompson LA, Farrell AP, Patterson DA, Miller KM.

J Fish Biol. 2011 Aug;79(2):449-65. doi: 10.1111/j.1095-8649.2011.03042.x.


Differences in thermal tolerance among sockeye salmon populations.

Eliason EJ, Clark TD, Hague MJ, Hanson LM, Gallagher ZS, Jeffries KM, Gale MK, Patterson DA, Hinch SG, Farrell AP.

Science. 2011 Apr 1;332(6025):109-12. doi: 10.1126/science.1199158.


First-line antiretroviral therapy with a protease inhibitor versus non-nucleoside reverse transcriptase inhibitor and switch at higher versus low viral load in HIV-infected children: an open-label, randomised phase 2/3 trial.

PENPACT-1 (PENTA 9/PACTG 390) Study Team, Babiker A, Castro nee Green H, Compagnucci A, Fiscus S, Giaquinto C, Gibb DM, Harper L, Harrison L, Hughes M, McKinney R, Melvin A, Mofenson L, Saidi Y, Smith ME, Tudor-Williams G, Walker AS.

Lancet Infect Dis. 2011 Apr;11(4):273-83. doi: 10.1016/S1473-3099(10)70313-3. Epub 2011 Jan 31.


Presence of natural and anthropogenic organic contaminants and potential fish health impacts along two river gradients in Alberta, Canada.

Jeffries KM, Jackson LJ, Ikonomou MG, Habibi HR.

Environ Toxicol Chem. 2010 Oct;29(10):2379-87. doi: 10.1002/etc.265.

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