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Items: 1 to 20 of 333

1.

A loss-of-function variant in OSBPL1A predisposes to low plasma HDL cholesterol levels and impaired cholesterol efflux capacity.

Motazacker MM, Pirhonen J, van Capelleveen JC, Weber-Boyvat M, Kuivenhoven JA, Shah S, Hovingh GK, Metso J, Li S, Ikonen E, Jauhiainen M, Dallinga-Thie GM, Olkkonen VM.

Atherosclerosis. 2016 Apr 11;249:140-147. doi: 10.1016/j.atherosclerosis.2016.04.005. [Epub ahead of print]

PMID:
27105157
2.

Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses.

Aho V, Ollila HM, Kronholm E, Bondia-Pons I, Soininen P, Kangas AJ, Hilvo M, Seppälä I, Kettunen J, Oikonen M, Raitoharju E, Hyötyläinen T, Kähönen M, Viikari JS, Härmä M, Sallinen M, Olkkonen VM, Alenius H, Jauhiainen M, Paunio T, Lehtimäki T, Salomaa V, Orešič M, Raitakari OT, Ala-Korpela M, Porkka-Heiskanen T.

Sci Rep. 2016 Apr 22;6:24828. doi: 10.1038/srep24828.

3.

Trim37-deficient mice recapitulate several features of the multi-organ disorder Mulibrey nanism.

Kettunen KM, Karikoski R, Hämäläinen RH, Toivonen TT, Antonenkov VD, Kulesskaya N, Voikar V, Hölttä-Vuori M, Ikonen E, Sainio K, Jalanko A, Karlberg S, Karlberg N, Lipsanen-Nyman M, Toppari J, Jauhiainen M, Hiltunen JK, Jalanko H, Lehesjoki AE.

Biol Open. 2016 Apr 3. pii: bio.016246. doi: 10.1242/bio.016246. [Epub ahead of print]

4.

Effects of angiopoietin-like protein 3 deficiency on postprandial lipid and lipoprotein metabolism.

Minicocci I, Tikka A, Poggiogalle E, Metso J, Montali A, Ceci F, Labbadia G, Fontana M, Di Costanzo A, Maranghi M, Rosano A, Ehnholm C, Donini LM, Jauhiainen M, Arca M.

J Lipid Res. 2016 Apr 3. pii: jlr.P066183. [Epub ahead of print]

5.

Low STAT3 expression sensitizes to toxic effects of β-adrenergic receptor stimulation in peripartum cardiomyopathy.

Stapel B, Kohlhaas M, Ricke-Hoch M, Haghikia A, Erschow S, Knuuti J, Silvola JM, Roivainen A, Saraste A, Nickel AG, Saar JA, Sieve I, Pietzsch S, Müller M, Bogeski I, Kappl R, Jauhiainen M, Thackeray JT, Scherr M, Bengel FM, Hagl C, Tudorache I, Bauersachs J, Maack C, Hilfiker-Kleiner D.

Eur Heart J. 2016 Mar 21. pii: ehw086. [Epub ahead of print]

PMID:
27002120
6.

Type 2 diabetes enhances arterial uptake of choline in atherosclerotic mice: an imaging study with positron emission tomography tracer ¹⁸F-fluoromethylcholine.

Hellberg S, Silvola JM, Kiugel M, Liljenbäck H, Metsälä O, Viljanen T, Metso J, Jauhiainen M, Saukko P, Nuutila P, Ylä-Herttuala S, Knuuti J, Roivainen A, Saraste A.

Cardiovasc Diabetol. 2016 Feb 6;15:26. doi: 10.1186/s12933-016-0340-6.

7.

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health.

Laurila PP, Soronen J, Kooijman S, Forsström S, Boon MR, Surakka I, Kaiharju E, Coomans CP, Van Den Berg SA, Autio A, Sarin AP, Kettunen J, Tikkanen E, Manninen T, Metso J, Silvennoinen R, Merikanto K, Ruuth M, Perttilä J, Mäkelä A, Isomi A, Tuomainen AM, Tikka A, Ramadan UA, Seppälä I, Lehtimäki T, Eriksson J, Havulinna A, Jula A, Karhunen PJ, Salomaa V, Perola M, Ehnholm C, Lee-Rueckert M, Van Eck M, Roivainen A, Taskinen MR, Peltonen L, Mervaala E, Jalanko A, Hohtola E, Olkkonen VM, Ripatti S, Kovanen PT, Rensen PC, Suomalainen A, Jauhiainen M.

Sci Transl Med. 2016 Jan 27;8(323):323ra13. doi: 10.1126/scitranslmed.aad0015.

PMID:
26819196
8.

The role of ANGPTL3 in controlling lipoprotein metabolism.

Tikka A, Jauhiainen M.

Endocrine. 2016 May;52(2):187-93. doi: 10.1007/s12020-015-0838-9. Epub 2016 Jan 11. Review.

9.

Carboxyl-Terminal Cleavage of Apolipoprotein A-I by Human Mast Cell Chymase Impairs Its Anti-Inflammatory Properties.

Nguyen SD, Maaninka K, Lappalainen J, Nurmi K, Metso J, Öörni K, Navab M, Fogelman AM, Jauhiainen M, Lee-Rueckert M, Kovanen PT.

Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):274-84. doi: 10.1161/ATVBAHA.115.306827. Epub 2015 Dec 17.

10.

Identification and analysis of anti-HDL scFv-antibodies obtained from phage display based synthetic antibody library.

Negi P, Lövgren J, Malmi P, Sirkka N, Metso J, Huovinen T, Brockmann EC, Pettersson K, Jauhiainen M, Lamminmäki U.

Clin Biochem. 2016 Apr;49(6):472-9. doi: 10.1016/j.clinbiochem.2015.11.020. Epub 2015 Dec 2.

PMID:
26656638
11.

Steroid sulfatase activity in subcutaneous and visceral adipose tissue: a comparison between pre- and postmenopausal women.

Paatela H, Wang F, Vihma V, Savolainen-Peltonen H, Mikkola TS, Turpeinen U, Hämäläinen E, Jauhiainen M, Tikkanen MJ.

Eur J Endocrinol. 2016 Feb;174(2):167-75. doi: 10.1530/EJE-15-0831. Epub 2015 Nov 9.

PMID:
26553725
12.

Nerve growth factor (NGF) and pro-NGF increase low-density lipoprotein (LDL) receptors in neuronal cells partly by different mechanisms: role of LDL in neurite outgrowth.

Do HT, Bruelle C, Pham DD, Jauhiainen M, Eriksson O, Korhonen LT, Lindholm D.

J Neurochem. 2016 Jan;136(2):306-15. doi: 10.1111/jnc.13397. Epub 2015 Nov 19.

PMID:
26484803
13.

Complement Factor H Binds to Human Serum Apolipoprotein E and Mediates Complement Regulation on High Density Lipoprotein Particles.

Haapasalo K, van Kessel K, Nissilä E, Metso J, Johansson T, Miettinen S, Varjosalo M, Kirveskari J, Kuusela P, Chroni A, Jauhiainen M, van Strijp J, Jokiranta TS.

J Biol Chem. 2015 Nov 27;290(48):28977-87. doi: 10.1074/jbc.M115.669226. Epub 2015 Oct 14.

PMID:
26468283
14.

Influence of Isoforms and Carboxyl-Terminal Truncations on the Capacity of Apolipoprotein E To Associate with and Activate Phospholipid Transfer Protein.

Dafnis I, Metso J, Zannis VI, Jauhiainen M, Chroni A.

Biochemistry. 2015 Sep 29;54(38):5856-66. doi: 10.1021/acs.biochem.5b00681. Epub 2015 Sep 17.

PMID:
26337529
15.

Regulation of Angiopoietin-Like Proteins (ANGPTLs) 3 and 8 by Insulin.

Nidhina Haridas PA, Soronen J, Sädevirta S, Mysore R, Quagliarini F, Pasternack A, Metso J, Perttilä J, Leivonen M, Smas CM, Fischer-Posovszky P, Wabitsch M, Ehnholm C, Ritvos O, Jauhiainen M, Olkkonen VM, Yki-Järvinen H.

J Clin Endocrinol Metab. 2015 Oct;100(10):E1299-307. doi: 10.1210/jc.2015-1254. Epub 2015 Jul 23.

PMID:
26204133
16.

Consumption of polyunsaturated fat improves the saturated fatty acid-mediated impairment of HDL antioxidant potential.

Cedó L, Metso J, Santos D, Sánchez-Quesada JL, Julve J, García-León A, Mora-Brugués J, Jauhiainen M, Blanco-Vaca F, Escolà-Gil JC.

Mol Nutr Food Res. 2015 Oct;59(10):1987-96. doi: 10.1002/mnfr.201500336. Epub 2015 Aug 12.

PMID:
26118785
17.

Coronary heart disease prediction: Apolipoprotein B shows its might again--but still in vain?

Kovanen PT, Jauhiainen M.

Eur J Prev Cardiol. 2015 Oct;22(10):1317-20. doi: 10.1177/2047487315580892. Epub 2015 Apr 14. No abstract available.

PMID:
25873630
18.

Partial filling affinity capillary electrophoresis including adsorption energy distribution calculations--towards reliable and feasible biomolecular interaction studies.

Witos J, Samuelsson J, Cilpa-Karhu G, Metso J, Jauhiainen M, Riekkola ML.

Analyst. 2015 May 7;140(9):3175-82. doi: 10.1039/c5an00210a. Epub 2015 Mar 9.

PMID:
25751597
19.

Remediating buildings damaged by dampness and mould for preventing or reducing respiratory tract symptoms, infections and asthma.

Sauni R, Verbeek JH, Uitti J, Jauhiainen M, Kreiss K, Sigsgaard T.

Cochrane Database Syst Rev. 2015 Feb 25;2:CD007897. doi: 10.1002/14651858.CD007897.pub3. Review.

PMID:
25715323
20.

PPAR-β/δ activation promotes phospholipid transfer protein expression.

Chehaibi K, Cedó L, Metso J, Palomer X, Santos D, Quesada H, Naceur Slimane M, Wahli W, Julve J, Vázquez-Carrera M, Jauhiainen M, Blanco-Vaca F, Escolà-Gil JC.

Biochem Pharmacol. 2015 Mar 15;94(2):101-8. doi: 10.1016/j.bcp.2015.01.016. Epub 2015 Feb 7.

PMID:
25662586
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