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Results: 1 to 20 of 105

1.

Toward effective software solutions for big biology.

Prins P, de Ligt J, Tarasov A, Jansen RC, Cuppen E, Bourne PE.

Nat Biotechnol. 2015 Jul 8;33(7):686-7. doi: 10.1038/nbt.3240. No abstract available.

PMID:
26154002
2.

Rate, spectrum, and evolutionary dynamics of spontaneous epimutations.

van der Graaf A, Wardenaar R, Neumann DA, Taudt A, Shaw RG, Jansen RC, Schmitz RJ, Colomé-Tatché M, Johannes F.

Proc Natl Acad Sci U S A. 2015 May 26;112(21):6676-81. doi: 10.1073/pnas.1424254112. Epub 2015 May 11.

3.

Cell Specific eQTL Analysis without Sorting Cells.

Westra HJ, Arends D, Esko T, Peters MJ, Schurmann C, Schramm K, Kettunen J, Yaghootkar H, Fairfax BP, Andiappan AK, Li Y, Fu J, Karjalainen J, Platteel M, Visschedijk M, Weersma RK, Kasela S, Milani L, Tserel L, Peterson P, Reinmaa E, Hofman A, Uitterlinden AG, Rivadeneira F, Homuth G, Petersmann A, Lorbeer R, Prokisch H, Meitinger T, Herder C, Roden M, Grallert H, Ripatti S, Perola M, Wood AR, Melzer D, Ferrucci L, Singleton AB, Hernandez DG, Knight JC, Melchiotti R, Lee B, Poidinger M, Zolezzi F, Larbi A, Wang de Y, van den Berg LH, Veldink JH, Rotzschke O, Makino S, Salomaa V, Strauch K, Völker U, van Meurs JB, Metspalu A, Wijmenga C, Jansen RC, Franke L.

PLoS Genet. 2015 May 8;11(5):e1005223. doi: 10.1371/journal.pgen.1005223. eCollection 2015 May.

4.

Pheno2Geno - High-throughput generation of genetic markers and maps from molecular phenotypes for crosses between inbred strains.

Zych K, Li Y, van der Velde JK, Joosen RV, Ligterink W, Jansen RC, Arends D.

BMC Bioinformatics. 2015 Feb 19;16:51. doi: 10.1186/s12859-015-0475-6.

5.

Gene expression analysis identifies global gene dosage sensitivity in cancer.

Fehrmann RS, Karjalainen JM, Krajewska M, Westra HJ, Maloney D, Simeonov A, Pers TH, Hirschhorn JN, Jansen RC, Schultes EA, van Haagen HH, de Vries EG, te Meerman GJ, Wijmenga C, van Vugt MA, Franke L.

Nat Genet. 2015 Feb;47(2):115-25. doi: 10.1038/ng.3173. Epub 2015 Jan 12.

PMID:
25581432
6.

Worm variation made accessible: Take your shopping cart to store, link, and investigate!

Snoek LB, Joeri van der Velde K, Li Y, Jansen RC, Swertz MA, Kammenga JE.

Worm. 2014 Jan 1;3(1):e28357. doi: 10.4161/worm.28357. Epub 2014 Mar 6.

7.

Natural variation of histone modification and its impact on gene expression in the rat genome.

Rintisch C, Heinig M, Bauerfeind A, Schafer S, Mieth C, Patone G, Hummel O, Chen W, Cook S, Cuppen E, Colomé-Tatché M, Johannes F, Jansen RC, Neil H, Werner M, Pravenec M, Vingron M, Hubner N.

Genome Res. 2014 Jun;24(6):942-53. doi: 10.1101/gr.169029.113. Epub 2014 May 2.

8.

Re: "The rise and fall of the 'minimum clinically important difference'".

Jansen RC.

Spine J. 2014 Apr;14(4):726. doi: 10.1016/j.spinee.2010.06.022. No abstract available.

PMID:
24655561
9.

Mapping the epigenetic basis of complex traits.

Cortijo S, Wardenaar R, Colomé-Tatché M, Gilly A, Etcheverry M, Labadie K, Caillieux E, Hospital F, Aury JM, Wincker P, Roudier F, Jansen RC, Colot V, Johannes F.

Science. 2014 Mar 7;343(6175):1145-8. doi: 10.1126/science.1248127. Epub 2014 Feb 6.

PMID:
24505129
10.

WormQTLHD--a web database for linking human disease to natural variation data in C. elegans.

van der Velde KJ, de Haan M, Zych K, Arends D, Snoek LB, Kammenga JE, Jansen RC, Swertz MA, Li Y.

Nucleic Acids Res. 2014 Jan;42(Database issue):D794-801. doi: 10.1093/nar/gkt1044. Epub 2013 Nov 11.

11.

Systematic identification of trans eQTLs as putative drivers of known disease associations.

Westra HJ, Peters MJ, Esko T, Yaghootkar H, Schurmann C, Kettunen J, Christiansen MW, Fairfax BP, Schramm K, Powell JE, Zhernakova A, Zhernakova DV, Veldink JH, Van den Berg LH, Karjalainen J, Withoff S, Uitterlinden AG, Hofman A, Rivadeneira F, 't Hoen PA, Reinmaa E, Fischer K, Nelis M, Milani L, Melzer D, Ferrucci L, Singleton AB, Hernandez DG, Nalls MA, Homuth G, Nauck M, Radke D, Völker U, Perola M, Salomaa V, Brody J, Suchy-Dicey A, Gharib SA, Enquobahrie DA, Lumley T, Montgomery GW, Makino S, Prokisch H, Herder C, Roden M, Grallert H, Meitinger T, Strauch K, Li Y, Jansen RC, Visscher PM, Knight JC, Psaty BM, Ripatti S, Teumer A, Frayling TM, Metspalu A, van Meurs JB, Franke L.

Nat Genet. 2013 Oct;45(10):1238-43. doi: 10.1038/ng.2756. Epub 2013 Sep 8.

12.

Pulmonary function after less invasive anterior instrumentation and fusion for idiopathic thoracic scoliosis.

Huitema GC, Jansen RC, Dompeling E, Willems P, Punt I, van Rhijn LW.

Scoliosis. 2013 Aug 21;8(1):14. doi: 10.1186/1748-7161-8-14.

13.
14.

Identifying genotype-by-environment interactions in the metabolism of germinating arabidopsis seeds using generalized genetical genomics.

Joosen RV, Arends D, Li Y, Willems LA, Keurentjes JJ, Ligterink W, Jansen RC, Hilhorst HW.

Plant Physiol. 2013 Jun;162(2):553-66. doi: 10.1104/pp.113.216176. Epub 2013 Apr 19.

15.

WormQTL--public archive and analysis web portal for natural variation data in Caenorhabditis spp.

Snoek LB, Van der Velde KJ, Arends D, Li Y, Beyer A, Elvin M, Fisher J, Hajnal A, Hengartner MO, Poulin GB, Rodriguez M, Schmid T, Schrimpf S, Xue F, Jansen RC, Kammenga JE, Swertz MA.

Nucleic Acids Res. 2013 Jan;41(Database issue):D738-43. doi: 10.1093/nar/gks1124. Epub 2012 Nov 24.

16.

Genome-wide methylation profiling identifies hypermethylated biomarkers in high-grade cervical intraepithelial neoplasia.

Lendvai Á, Johannes F, Grimm C, Eijsink JJ, Wardenaar R, Volders HH, Klip HG, Hollema H, Jansen RC, Schuuring E, Wisman GB, van der Zee AG.

Epigenetics. 2012 Nov;7(11):1268-78. doi: 10.4161/epi.22301. Epub 2012 Sep 27.

17.

Features of the Arabidopsis recombination landscape resulting from the combined loss of sequence variation and DNA methylation.

Colomé-Tatché M, Cortijo S, Wardenaar R, Morgado L, Lahouze B, Sarazin A, Etcheverry M, Martin A, Feng S, Duvernois-Berthet E, Labadie K, Wincker P, Jacobsen SE, Jansen RC, Colot V, Johannes F.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16240-5. doi: 10.1073/pnas.1212955109. Epub 2012 Sep 17.

18.

Chronic pain, associated factors, and impact on daily life: are there differences between the sexes?

Vieira EB, Garcia JB, Silva AA, Araújo RL, Jansen RC, Bertrand AL.

Cad Saude Publica. 2012 Aug;28(8):1459-67.

19.

Prevalence, characteristics, and factors associated with chronic pain with and without neuropathic characteristics in São Luís, Brazil.

de Moraes Vieira EB, Garcia JB, da Silva AA, Mualem Araújo RL, Jansen RC.

J Pain Symptom Manage. 2012 Aug;44(2):239-51. doi: 10.1016/j.jpainsymman.2011.08.014.

PMID:
22871508
20.

Quantile-based permutation thresholds for quantitative trait loci hotspots.

Neto EC, Keller MP, Broman AF, Attie AD, Jansen RC, Broman KW, Yandell BS.

Genetics. 2012 Aug;191(4):1355-65. doi: 10.1534/genetics.112.139451. Epub 2012 Jun 1.

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