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Results: 1 to 20 of 281

1.

Pre-clinical Specificity and Safety of UC-961, a First-In-Class Monoclonal Antibody Targeting ROR1.

Choi MY, Widhopf GF 2nd, Wu CC, Cui B, Lao F, Sadarangani A, Cavagnaro J, Prussak C, Carson DA, Jamieson C, Kipps TJ.

Clin Lymphoma Myeloma Leuk. 2015 Jun;15 Suppl:S167-9. doi: 10.1016/j.clml.2015.02.010. Review.

2.

RNA rewriting, recoding, and rewiring in human disease.

Zipeto MA, Jiang Q, Melese E, Jamieson CH.

Trends Mol Med. 2015 Aug 7. pii: S1471-4914(15)00134-3. doi: 10.1016/j.molmed.2015.07.001. [Epub ahead of print] Review.

PMID:
26259769
3.

A phase 2 randomized dose-ranging study of the JAK2-selective inhibitor fedratinib (SAR302503) in patients with myelofibrosis.

Pardanani A, Tefferi A, Jamieson C, Gabrail NY, Lebedinsky C, Gao G, Liu F, Xu C, Cao H, Talpaz M.

Blood Cancer J. 2015 Aug 7;5:e335. doi: 10.1038/bcj.2015.63.

PMID:
26252788
4.

The hydrophobic rich N- and C-terminal tails of β-catenin facilitate nuclear import.

Sharma M, Jamieson C, Lui C, Henderson BR.

J Biol Chem. 2015 Jul 24;290(30):18479. doi: 10.1074/jbc.A114.603209. No abstract available.

5.

The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits.

Bertrand SM, Ancellin N, Beaufils B, Bingham RP, Borthwick JA, Boullay AB, Boursier E, Carter PS, Chung CW, Churcher I, Dodic N, Fouchet MH, Fournier C, Francis PL, Gummer LA, Herry K, Hobbs A, Hobbs CI, Homes P, Jamieson C, Nicodeme E, Pickett SD, Reid IH, Simpson GL, Sloan LA, Smith SE, Somers DO, Spitzfaden C, Suckling CJ, Valko K, Washio Y, Young RJ.

J Med Chem. 2015 Jul 2. [Epub ahead of print]

PMID:
26090771
6.

Catalytic amidation of unactivated ester derivatives mediated by trifluoroethanol.

Caldwell N, Jamieson C, Simpson I, Watson AJ.

Chem Commun (Camb). 2015 Jun 11;51(46):9495-8. doi: 10.1039/c5cc02895g.

PMID:
25966325
7.

Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy.

Shalapour S, Font-Burgada J, Di Caro G, Zhong Z, Sanchez-Lopez E, Dhar D, Willimsky G, Ammirante M, Strasner A, Hansel DE, Jamieson C, Kane CJ, Klatte T, Birner P, Kenner L, Karin M.

Nature. 2015 May 7;521(7550):94-8. doi: 10.1038/nature14395. Epub 2015 Apr 29.

PMID:
25924065
8.

Rational Design of a Novel AMPA Receptor Modulator through a Hybridization Approach.

Caldwell N, Harms JE, Partin KM, Jamieson C.

ACS Med Chem Lett. 2015 Feb 11;6(4):392-6. doi: 10.1021/ml5004553. eCollection 2015 Apr 9.

PMID:
25893038
9.

GLI2 inhibition abrogates human leukemia stem cell dormancy.

Sadarangani A, Pineda G, Lennon KM, Chun HJ, Shih A, Schairer AE, Court AC, Goff DJ, Prashad SL, Geron I, Wall R, McPherson JD, Moore RA, Pu M, Bao L, Jackson-Fisher A, Munchhof M, VanArsdale T, Reya T, Morris SR, Minden MD, Messer K, Mikkola HK, Marra MA, Hudson TJ, Jamieson CH.

J Transl Med. 2015 Mar 21;13:98. doi: 10.1186/s12967-015-0453-9.

10.

An RNA editing fingerprint of cancer stem cell reprogramming.

Crews LA, Jiang Q, Zipeto MA, Lazzari E, Court AC, Ali S, Barrett CL, Frazer KA, Jamieson CH.

J Transl Med. 2015 Feb 12;13:52. doi: 10.1186/s12967-014-0370-3.

11.

Historical views, conventional approaches, and evolving management strategies for myeloproliferative neoplasms.

Stein BL, Gotlib J, Arcasoy M, Nguyen MH, Shah N, Moliterno A, Jamieson C, Pollyea DA, Scott B, Wadleigh M, Levine R, Komrokji R, Klisovic R, Gundabolu K, Kropf P, Wetzler M, Oh ST, Ribeiro R, Paschal R, Mohan S, Podoltsev N, Prchal J, Talpaz M, Snyder D, Verstovsek S, Mesa RA.

J Natl Compr Canc Netw. 2015 Apr;13(4):424-34.

PMID:
25870379
12.

Genetic and epigenetic profiling of CLL disease progression reveals limited somatic evolution and suggests a relationship to memory-cell development.

Smith EN, Ghia EM, DeBoever CM, Rassenti LZ, Jepsen K, Yoon KA, Matsui H, Rozenzhak S, Alakus H, Shepard PJ, Dai Y, Khosroheidari M, Bina M, Gunderson KL, Messer K, Muthuswamy L, Hudson TJ, Harismendy O, Barrett CL, Jamieson CH, Carson DA, Kipps TJ, Frazer KA.

Blood Cancer J. 2015 Apr 10;5:e303. doi: 10.1038/bcj.2015.14.

13.

Transcriptome sequencing reveals potential mechanism of cryptic 3' splice site selection in SF3B1-mutated cancers.

DeBoever C, Ghia EM, Shepard PJ, Rassenti L, Barrett CL, Jepsen K, Jamieson CH, Carson D, Kipps TJ, Frazer KA.

PLoS Comput Biol. 2015 Mar 13;11(3):e1004105. doi: 10.1371/journal.pcbi.1004105. eCollection 2015 Mar.

14.

WITHDRAWN: The hydrophobic rich N- and C-terminal tails of beta-catenin facilitate nuclear import of beta-catenin.

Sharma M, Jamieson C, Lui C, Henderson BR.

J Biol Chem. 2014 Dec 3. pii: jbc.M114.603209. [Epub ahead of print]

15.

Novel insights into the biology and treatment of chronic myeloproliferative neoplasms.

Mughal TI, Barbui T, Abdel-Wahab O, Kralovics R, Jamieson C, Kvasnicka HM, Mullaly A, Rampal R, Mesa R, Kiladjian JJ, Deininger M, Prchal J, Hehlmann R, Saglio G, Van Etten RA.

Leuk Lymphoma. 2015 Jul;56(7):1938-48. doi: 10.3109/10428194.2014.974594. Epub 2014 Nov 19.

PMID:
25330439
16.

PCSD1, a new patient-derived model of bone metastatic prostate cancer, is castrate-resistant in the bone-niche.

Godebu E, Muldong M, Strasner A, Wu CN, Park SC, Woo JR, Ma W, Liss MA, Hirata T, Raheem O, Cacalano NA, Kulidjian AA, Jamieson CA.

J Transl Med. 2014 Oct 3;12:275. doi: 10.1186/s12967-014-0275-1.

17.

Tissue injury and hypoxia promote malignant progression of prostate cancer by inducing CXCL13 expression in tumor myofibroblasts.

Ammirante M, Shalapour S, Kang Y, Jamieson CA, Karin M.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14776-81. doi: 10.1073/pnas.1416498111. Epub 2014 Sep 29.

18.

Amidation of esters with amino alcohols using organobase catalysis.

Caldwell N, Campbell PS, Jamieson C, Potjewyd F, Simpson I, Watson AJ.

J Org Chem. 2014 Oct 3;79(19):9347-54. doi: 10.1021/jo501929c. Epub 2014 Sep 16.

PMID:
25226088
19.

Biased estimates of clonal evolution and subclonal heterogeneity can arise from PCR duplicates in deep sequencing experiments.

Smith EN, Jepsen K, Khosroheidari M, Rassenti LZ, D'Antonio M, Ghia EM, Carson DA, Jamieson CH, Kipps TJ, Frazer KA.

Genome Biol. 2014 Aug 7;15(8):420. doi: 10.1186/s13059-014-0420-4.

20.

SUMV-1 antagonizes the activity of synthetic multivulva genes in Caenorhabditis elegans.

Yücel D, Hoe M, Llamosas E, Kant S, Jamieson C, Young PA, Crossley M, Nicholas HR.

Dev Biol. 2014 Aug 15;392(2):266-82. doi: 10.1016/j.ydbio.2014.05.018. Epub 2014 Jun 2.

PMID:
24882710
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