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Results: 1 to 20 of 61


Immunomodulatory action of the DNA methyltransferase inhibitor SGI-110 in epithelial ovarian cancer cells and xenografts.

Srivastava P, Paluch BE, Matsuzaki J, James SR, Collamat-Lai G, Taverna P, Karpf AR, Griffiths EA.

Epigenetics. 2015 Mar 4;10(3):237-46. doi: 10.1080/15592294.2015.1017198.


Pharmacological targeting of β-catenin in normal karyotype acute myeloid leukemia blasts.

Griffiths EA, Golding MC, Srivastava P, Povinelli BJ, James SR, Ford LA, Wetzler M, Wang ES, Nemeth MJ.

Haematologica. 2015 Feb;100(2):e49-52. doi: 10.3324/haematol.2014.113118. Epub 2014 Nov 7. No abstract available.


Immunomodulatory action of SGI-110, a hypomethylating agent, in acute myeloid leukemia cells and xenografts.

Srivastava P, Paluch BE, Matsuzaki J, James SR, Collamat-Lai G, Karbach J, Nemeth MJ, Taverna P, Karpf AR, Griffiths EA.

Leuk Res. 2014 Nov;38(11):1332-41. doi: 10.1016/j.leukres.2014.09.001. Epub 2014 Sep 10.


Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal.

Ptasinska A, Assi SA, Martinez-Soria N, Imperato MR, Piper J, Cauchy P, Pickin A, James SR, Hoogenkamp M, Williamson D, Wu M, Tenen DG, Ott S, Westhead DR, Cockerill PN, Heidenreich O, Bonifer C.

Cell Rep. 2014 Sep 25;8(6):1974-88. doi: 10.1016/j.celrep.2014.08.024. Epub 2014 Sep 18.


Epigenetic potentiation of NY-ESO-1 vaccine therapy in human ovarian cancer.

Odunsi K, Matsuzaki J, James SR, Mhawech-Fauceglia P, Tsuji T, Miller A, Zhang W, Akers SN, Griffiths EA, Miliotto A, Beck A, Batt CA, Ritter G, Lele S, Gnjatic S, Karpf AR.

Cancer Immunol Res. 2014 Jan;2(1):37-49. doi: 10.1158/2326-6066.CIR-13-0126.


DNA methylation and nucleosome occupancy regulate the cancer germline antigen gene MAGEA11.

James SR, Cedeno CD, Sharma A, Zhang W, Mohler JL, Odunsi K, Wilson EM, Karpf AR.

Epigenetics. 2013 Aug;8(8):849-63. doi: 10.4161/epi.25500. Epub 2013 Jul 9.


The inducible tissue-specific expression of the human IL-3/GM-CSF locus is controlled by a complex array of developmentally regulated enhancers.

Baxter EW, Mirabella F, Bowers SR, James SR, Bonavita AM, Bertrand E, Strogantsev R, Hawwari A, Bert AG, Gonzalez de Arce A, West AG, Bonifer C, Cockerill PN.

J Immunol. 2012 Nov 1;189(9):4459-69. doi: 10.4049/jimmunol.1201915. Epub 2012 Sep 28.


Induction of differentiation and apoptosis in leukaemic cell lines by the novel benzamide family histone deacetylase 2 and 3 inhibitor MI-192.

Boissinot M, Inman M, Hempshall A, James SR, Gill JH, Selby P, Bowen DT, Grigg R, Cockerill PN.

Leuk Res. 2012 Oct;36(10):1304-10. doi: 10.1016/j.leukres.2012.07.002. Epub 2012 Jul 20.


Insufficient DNA methylation affects healthy aging and promotes age-related health problems.

Liu L, van Groen T, Kadish I, Li Y, Wang D, James SR, Karpf AR, Tollefsbol TO.

Clin Epigenetics. 2011 Aug;2(2):349-60. doi: 10.1007/s13148-011-0042-6. Epub 2011 Jun 12.


Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding.

Ptasinska A, Assi SA, Mannari D, James SR, Williamson D, Dunne J, Hoogenkamp M, Wu M, Care M, McNeill H, Cauchy P, Cullen M, Tooze RM, Tenen DG, Young BD, Cockerill PN, Westhead DR, Heidenreich O, Bonifer C.

Leukemia. 2012 Aug;26(8):1829-41. doi: 10.1038/leu.2012.49. Epub 2012 Feb 20.


Gene therapy for chronic neuropathic pain: how does it work and where do we stand today?

Kumar S, Ruchi R, James SR, Chidiac EJ.

Pain Med. 2011 May;12(5):808-22. doi: 10.1111/j.1526-4637.2011.01120.x. Review.


BORIS/CTCFL expression is insufficient for cancer-germline antigen gene expression and DNA hypomethylation in ovarian cell lines.

Woloszynska-Read A, James SR, Song C, Jin B, Odunsi K, Karpf AR.

Cancer Immun. 2010 Jul 23;10:6.


Transcriptional and epigenetic regulation of the GM-CSF promoter by RUNX1.

Oakford PC, James SR, Qadi A, West AC, Ray SN, Bert AG, Cockerill PN, Holloway AF.

Leuk Res. 2010 Sep;34(9):1203-13. doi: 10.1016/j.leukres.2010.03.029. Epub 2010 May 1.


N-terminal pro-brain-type natriuretic peptide: a biochemical surrogate of cardiac function in the potential heart donor.

Dronavalli VB, Ranasinghe AM, Venkateswaran RJ, James SR, McCabe CJ, Wilson IC, Mascaro JG, Bonser RS.

Eur J Cardiothorac Surg. 2010 Aug;38(2):181-6. doi: 10.1016/j.ejcts.2010.01.024. Epub 2010 Feb 23.


The human IL-3/granulocyte-macrophage colony-stimulating factor locus is epigenetically silent in immature thymocytes and is progressively activated during T cell development.

Mirabella F, Baxter EW, Boissinot M, James SR, Cockerill PN.

J Immunol. 2010 Mar 15;184(6):3043-54. doi: 10.4049/jimmunol.0901364. Epub 2010 Feb 10.


The effects of acute triiodothyronine therapy on myocardial gene expression in brain stem dead cardiac donors.

James SR, Ranasinghe AM, Venkateswaran R, McCabe CJ, Franklyn JA, Bonser RS.

J Clin Endocrinol Metab. 2010 Mar;95(3):1338-43. doi: 10.1210/jc.2009-1659. Epub 2010 Jan 15.


Mechanisms of epigenetic silencing of the Rassf1a gene during estrogen-induced breast carcinogenesis in ACI rats.

Starlard-Davenport A, Tryndyak VP, James SR, Karpf AR, Latendresse JR, Beland FA, Pogribny IP.

Carcinogenesis. 2010 Mar;31(3):376-81. doi: 10.1093/carcin/bgp304. Epub 2009 Dec 14.


Dnmt3 and G9a cooperate for tissue-specific development in zebrafish.

Rai K, Jafri IF, Chidester S, James SR, Karpf AR, Cairns BR, Jones DA.

J Biol Chem. 2010 Feb 5;285(6):4110-21. doi: 10.1074/jbc.M109.073676. Epub 2009 Nov 29.


A novel mechanism of sodium iodide symporter repression in differentiated thyroid cancer.

Smith VE, Read ML, Turnell AS, Watkins RJ, Watkinson JC, Lewy GD, Fong JC, James SR, Eggo MC, Boelaert K, Franklyn JA, McCabe CJ.

J Cell Sci. 2009 Sep 15;122(Pt 18):3393-402. doi: 10.1242/jcs.045427. Epub 2009 Aug 25.


Association between global DNA hypomethylation in leukocytes and risk of breast cancer.

Choi JY, James SR, Link PA, McCann SE, Hong CC, Davis W, Nesline MK, Ambrosone CB, Karpf AR.

Carcinogenesis. 2009 Nov;30(11):1889-97. doi: 10.1093/carcin/bgp143. Epub 2009 Jul 7.

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