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Results: 1 to 20 of 231


EAG2 potassium channel with evolutionarily conserved function as a brain tumor target.

Huang X, He Y, Dubuc AM, Hashizume R, Zhang W, Reimand J, Yang H, Wang TA, Stehbens SJ, Younger S, Barshow S, Zhu S, Cooper MK, Peacock J, Ramaswamy V, Garzia L, Wu X, Remke M, Forester CM, Kim CC, Weiss WA, James CD, Shuman MA, Bader GD, Mueller S, Taylor MD, Jan YN, Jan LY.

Nat Neurosci. 2015 Sep;18(9):1236-46. doi: 10.1038/nn.4088. Epub 2015 Aug 10.


EGFR blockade prevents glioma escape from BRAFV600E targeted therapy.

Yao TW, Zhang J, Prados M, Weiss WA, James CD, Nicolaides T.

Oncotarget. 2015 May 22. [Epub ahead of print]


Induction frequency affects cortico-striatal synaptic plasticity with implications for frequency filtering.

Baca M, Schiess AR, Jelenik D, James CD, Donald Partridge L.

Brain Res. 2015 Jul 30;1615:80-8. doi: 10.1016/j.brainres.2015.04.031. Epub 2015 Apr 23.


The human papillomavirus type 16 L1 protein directly interacts with E2 and enhances E2-dependent replication and transcription activation.

Siddiqa A, Léon KC, James CD, Bhatti MF, Roberts S, Parish JL.

J Gen Virol. 2015 Aug;96(8):2274-85. doi: 10.1099/vir.0.000162. Epub 2015 Apr 24.


miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma.

Kouri FM, Hurley LA, Daniel WL, Day ES, Hua Y, Hao L, Peng CY, Merkel TJ, Queisser MA, Ritner C, Zhang H, James CD, Sznajder JI, Chin L, Giljohann DA, Kessler JA, Peter ME, Mirkin CA, Stegh AH.

Genes Dev. 2015 Apr 1;29(7):732-45. doi: 10.1101/gad.257394.114.


Challenges in EGFRvIII detection in head and neck squamous cell carcinoma.

Wheeler SE, Egloff AM, Wang L, James CD, Hammerman PS, Grandis JR.

PLoS One. 2015 Feb 6;10(2):e0117781. doi: 10.1371/journal.pone.0117781. eCollection 2015.


Radiotherapy followed by aurora kinase inhibition targets tumor-propagating cells in human glioblastoma.

Li N, Maly DJ, Chanthery YH, Sirkis DW, Nakamura JL, Berger MS, James CD, Shokat KM, Weiss WA, Persson AI.

Mol Cancer Ther. 2015 Feb;14(2):419-28. doi: 10.1158/1535-7163.MCT-14-0526. Epub 2014 Dec 18.


Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor α.

Feng H, Li Y, Yin Y, Zhang W, Hou Y, Zhang L, Li Z, Xie B, Gao WQ, Sarkaria JN, Raizer JJ, James CD, Parsa AT, Hu B, Cheng SY.

Neuro Oncol. 2015 Jun;17(6):832-42. doi: 10.1093/neuonc/nou323. Epub 2014 Dec 2.


Stable luciferase expression does not alter immunologic or in vivo growth properties of GL261 murine glioma cells.

Clark AJ, Safaee M, Oh T, Ivan ME, Parimi V, Hashizume R, Ozawa T, James CD, Bloch O, Parsa AT.

J Transl Med. 2014 Dec 3;12:345. doi: 10.1186/s12967-014-0345-4.


Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.

Hashizume R, Andor N, Ihara Y, Lerner R, Gan H, Chen X, Fang D, Huang X, Tom MW, Ngo V, Solomon D, Mueller S, Paris PL, Zhang Z, Petritsch C, Gupta N, Waldman TA, James CD.

Nat Med. 2014 Dec;20(12):1394-6. doi: 10.1038/nm.3716. Epub 2014 Nov 17.


NT113, a pan-ERBB inhibitor with high brain penetrance, inhibits the growth of glioblastoma xenografts with EGFR amplification.

Yoshida Y, Ozawa T, Yao TW, Shen W, Brown D, Parsa AT, Raizer JJ, Cheng SY, Stegh AH, Mazar AP, Giles FJ, Sarkaria JN, Butowski N, Nicolaides T, James CD.

Mol Cancer Ther. 2014 Dec;13(12):2919-29. doi: 10.1158/1535-7163.MCT-14-0306. Epub 2014 Oct 13.


Isothermal switching and detailed filament evolution in memristive systems.

Mickel PR, Lohn AJ, James CD, Marinella MJ.

Adv Mater. 2014 Jul 9;26(26):4486-90. doi: 10.1002/adma.201306182. Epub 2014 Apr 29.


Immunocompetent murine models for the study of glioblastoma immunotherapy.

Oh T, Fakurnejad S, Sayegh ET, Clark AJ, Ivan ME, Sun MZ, Safaee M, Bloch O, James CD, Parsa AT.

J Transl Med. 2014 Apr 29;12:107. doi: 10.1186/1479-5876-12-107. Review.


Adjuvant radiotherapy for atypical and malignant meningiomas: a systematic review.

Kaur G, Sayegh ET, Larson A, Bloch O, Madden M, Sun MZ, Barani IJ, James CD, Parsa AT.

Neuro Oncol. 2014 May;16(5):628-36. doi: 10.1093/neuonc/nou025. Epub 2014 Apr 2. Review.


Stainless steel versus titanium volar multi-axial locking plates for fixation of distal radius fractures: a randomised clinical trial.

Couzens GB, Peters SE, Cutbush K, Hope B, Taylor F, James CD, Rankin CR, Ross M.

BMC Musculoskelet Disord. 2014 Mar 11;15:74. doi: 10.1186/1471-2474-15-74.


Response of primary glioblastoma cells to therapy is patient specific and independent of cancer stem cell phenotype.

Fouse SD, Nakamura JL, James CD, Chang S, Costello JF.

Neuro Oncol. 2014 Mar;16(3):361-71. doi: 10.1093/neuonc/not223. Epub 2013 Dec 4.


Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.

Nathanson DA, Gini B, Mottahedeh J, Visnyei K, Koga T, Gomez G, Eskin A, Hwang K, Wang J, Masui K, Paucar A, Yang H, Ohashi M, Zhu S, Wykosky J, Reed R, Nelson SF, Cloughesy TF, James CD, Rao PN, Kornblum HI, Heath JR, Cavenee WK, Furnari FB, Mischel PS.

Science. 2014 Jan 3;343(6166):72-6. doi: 10.1126/science.1241328. Epub 2013 Dec 5.


Targeting Wee1 for the treatment of pediatric high-grade gliomas.

Mueller S, Hashizume R, Yang X, Kolkowitz I, Olow AK, Phillips J, Smirnov I, Tom MW, Prados MD, James CD, Berger MS, Gupta N, Haas-Kogan DA.

Neuro Oncol. 2014 Mar;16(3):352-60. doi: 10.1093/neuonc/not220. Epub 2013 Dec 4.


Cidofovir: a novel antitumor agent for glioblastoma.

Hadaczek P, Ozawa T, Soroceanu L, Yoshida Y, Matlaf L, Singer E, Fiallos E, James CD, Cobbs CS.

Clin Cancer Res. 2013 Dec 1;19(23):6473-83. doi: 10.1158/1078-0432.CCR-13-1121. Epub 2013 Oct 29.


Frequent truncating mutations of STAG2 in bladder cancer.

Solomon DA, Kim JS, Bondaruk J, Shariat SF, Wang ZF, Elkahloun AG, Ozawa T, Gerard J, Zhuang D, Zhang S, Navai N, Siefker-Radtke A, Phillips JJ, Robinson BD, Rubin MA, Volkmer B, Hautmann R, Küfer R, Hogendoorn PC, Netto G, Theodorescu D, James CD, Czerniak B, Miettinen M, Waldman T.

Nat Genet. 2013 Dec;45(12):1428-30. doi: 10.1038/ng.2800. Epub 2013 Oct 13.

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