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Results: 1 to 20 of 45

1.

Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux.

O'Brien LC, Keeney PM, Bennett JP Jr.

Stem Cells Dev. 2015 Apr 19. [Epub ahead of print]

PMID:
25892363
2.

Postmortem Alzheimer's Disease Hippocampi Show Oxidative Phosphorylation Gene Expression Opposite that of Isolated Pyramidal Neurons.

Rice AC, Ladd AC, Bennett JP Jr.

J Alzheimers Dis. 2015 Jan 1;45(4):1051-9. doi: 10.3233/JAD-142937.

PMID:
25720395
3.

Mitochondrial oxidative phosphorylation transcriptome alterations in human amyotrophic lateral sclerosis spinal cord and blood.

Ladd AC, Keeney PM, Govind MM, Bennett JP Jr.

Neuromolecular Med. 2014 Dec;16(4):714-26. doi: 10.1007/s12017-014-8321-y. Epub 2014 Aug 1.

PMID:
25081190
4.

Mortality in levodopa-treated Parkinson's disease.

Morgan JC, Currie LJ, Harrison MB, Bennett JP Jr, Trugman JM, Wooten GF.

Parkinsons Dis. 2014;2014:426976. doi: 10.1155/2014/426976. Epub 2014 Jan 28.

5.

Mitochondrial DNA copy numbers in pyramidal neurons are decreased and mitochondrial biogenesis transcriptome signaling is disrupted in Alzheimer's disease hippocampi.

Rice AC, Keeney PM, Algarzae NK, Ladd AC, Thomas RR, Bennett JP Jr.

J Alzheimers Dis. 2014;40(2):319-30. doi: 10.3233/JAD-131715.

PMID:
24448779
6.

Mitochondrial quality, dynamics and functional capacity in Parkinson's disease cybrid cell lines selected for Lewy body expression.

Cronin-Furman EN, Borland MK, Bergquist KE, Bennett JP Jr, Trimmer PA.

Mol Neurodegener. 2013 Jan 26;8:6. doi: 10.1186/1750-1326-8-6.

7.

RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice.

Thomas RR, Khan SM, Smigrodzki RM, Onyango IG, Dennis J, Khan OM, Portelli FR, Bennett JP Jr.

Aging (Albany NY). 2012 Sep;4(9):620-35.

8.

Lichens: unexpected anti-prion agents?

Rodriguez CM, Bennett JP, Johnson CJ.

Prion. 2012 Jan-Mar;6(1):11-6. doi: 10.4161/pri.6.1.17414. Review.

9.

Mitochondrial gene therapy improves respiration, biogenesis, and transcription in G11778A Leber's hereditary optic neuropathy and T8993G Leigh's syndrome cells.

Iyer S, Bergquist K, Young K, Gnaiger E, Rao RR, Bennett JP Jr.

Hum Gene Ther. 2012 Jun;23(6):647-57. doi: 10.1089/hum.2011.177. Epub 2012 Apr 17.

10.

Impaired complex-I mitochondrial biogenesis in Parkinson disease frontal cortex.

Thomas RR, Keeney PM, Bennett JP.

J Parkinsons Dis. 2012;2(1):67-76. doi: 10.3233/JPD-2012-11074.

PMID:
23939409
11.

The dying of the light: mitochondrial failure in Alzheimer's disease.

Young-Collier KJ, McArdle M, Bennett JP.

J Alzheimers Dis. 2012;28(4):771-81. doi: 10.3233/JAD-2011-111487.

PMID:
22057028
12.

Degradation of the disease-associated prion protein by a serine protease from lichens.

Johnson CJ, Bennett JP, Biro SM, Duque-Velasquez JC, Rodriguez CM, Bessen RA, Rocke TE.

PLoS One. 2011 May 11;6(5):e19836. doi: 10.1371/journal.pone.0019836.

13.

Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin.

Thomas RR, Khan SM, Portell FR, Smigrodzki RM, Bennett JP Jr.

Mitochondrion. 2011 Jan;11(1):108-18. doi: 10.1016/j.mito.2010.08.004. Epub 2010 Aug 18.

14.

Nerve growth factor attenuates oxidant-induced β-amyloid neurotoxicity in sporadic Alzheimer's disease cybrids.

Onyango IG, Ahn JY, Tuttle JB, Bennett JP Jr, Swerdlow RH.

J Neurochem. 2010 Sep;114(6):1605-18. doi: 10.1111/j.1471-4159.2010.06871.x. Epub 2010 Jul 30.

PMID:
20561151
15.

ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions.

Keeney PM, Bennett JP Jr.

Mol Neurodegener. 2010 May 26;5:21. doi: 10.1186/1750-1326-5-21.

16.

The mitochondrial secret(ase) of Alzheimer's disease.

Young KJ, Bennett JP.

J Alzheimers Dis. 2010;20 Suppl 2:S381-400. doi: 10.3233/JAD-2010-100360. Review.

PMID:
20442493
17.

Cybrid models of Parkinson's disease show variable mitochondrial biogenesis and genotype-respiration relationships.

Keeney PM, Dunham LD, Quigley CK, Morton SL, Bergquist KE, Bennett JP Jr.

Exp Neurol. 2009 Dec;220(2):374-82. doi: 10.1016/j.expneurol.2009.09.025. Epub 2009 Oct 6.

18.
19.

Recombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression.

Iyer S, Thomas RR, Portell FR, Dunham LD, Quigley CK, Bennett JP Jr.

Mitochondrion. 2009 Jun;9(3):196-203. doi: 10.1016/j.mito.2009.01.012. Epub 2009 Feb 4.

20.

Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model.

Keeney PM, Quigley CK, Dunham LD, Papageorge CM, Iyer S, Thomas RR, Schwarz KM, Trimmer PA, Khan SM, Portell FR, Bergquist KE, Bennett JP Jr.

Hum Gene Ther. 2009 Aug;20(8):897-907. doi: 10.1089/hum.2009.023.

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