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Results: 1 to 20 of 350

1.

In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse.

Morselli M, Pastor WA, Montanini B, Nee K, Ferrari R, Fu K, Bonora G, Rubbi L, Clark AT, Ottonello S, Jacobsen SE, Pellegrini M.

Elife. 2015 Apr 7;4. doi: 10.7554/eLife.06205.

2.

Synthesis and pharmacological evaluation of N-benzyl substituted 4-bromo-2,5-dimethoxyphenethylamines as 5-HT2A/2C partial agonists.

Hansen M, Jacobsen SE, Plunkett S, Liebscher GE, McCorvy JD, Bräuner-Osborne H, Kristensen JL.

Bioorg Med Chem. 2014 Dec 17. pii: S0968-0896(14)00859-1. doi: 10.1016/j.bmc.2014.12.011. [Epub ahead of print]

PMID:
25583099
3.

Domains rearranged methyltransferase3 controls DNA methylation and regulates RNA polymerase V transcript abundance in Arabidopsis.

Zhong X, Hale CJ, Nguyen M, Ausin I, Groth M, Hetzel J, Vashisht AA, Henderson IR, Wohlschlegel JA, Jacobsen SE.

Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):911-6. doi: 10.1073/pnas.1423603112. Epub 2015 Jan 5.

PMID:
25561521
4.

Rare allele of a previously unidentified histone H4 acetyltransferase enhances grain weight, yield, and plant biomass in rice.

Song XJ, Kuroha T, Ayano M, Furuta T, Nagai K, Komeda N, Segami S, Miura K, Ogawa D, Kamura T, Suzuki T, Higashiyama T, Yamasaki M, Mori H, Inukai Y, Wu J, Kitano H, Sakakibara H, Jacobsen SE, Ashikari M.

Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):76-81. doi: 10.1073/pnas.1421127112. Epub 2014 Dec 22.

5.

MORC1 represses transposable elements in the mouse male germline.

Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc'his D, Aravin AA, Clark AT, Jacobsen SE.

Nat Commun. 2014 Dec 12;5:5795. doi: 10.1038/ncomms6795.

6.

SNF2 chromatin remodeler-family proteins FRG1 and -2 are required for RNA-directed DNA methylation.

Groth M, Stroud H, Feng S, Greenberg MV, Vashisht AA, Wohlschlegel JA, Jacobsen SE, Ausin I.

Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17666-71. doi: 10.1073/pnas.1420515111. Epub 2014 Nov 25.

7.

Effect of saline water on seed germination and early seedling growth of the halophyte quinoa.

Panuccio MR, Jacobsen SE, Akhtar SS, Muscolo A.

AoB Plants. 2014 Aug 19;6. pii: plu047. doi: 10.1093/aobpla/plu047.

8.

Genome-wide Hi-C analyses in wild-type and mutants reveal high-resolution chromatin interactions in Arabidopsis.

Feng S, Cokus SJ, Schubert V, Zhai J, Pellegrini M, Jacobsen SE.

Mol Cell. 2014 Sep 4;55(5):694-707. doi: 10.1016/j.molcel.2014.07.008. Epub 2014 Aug 14.

PMID:
25132175
9.

Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation.

Tsagaratou A, Äijö T, Lio CW, Yue X, Huang Y, Jacobsen SE, Lähdesmäki H, Rao A.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3306-15. doi: 10.1073/pnas.1412327111. Epub 2014 Jul 28.

10.

Risk of multiple myeloma is associated with polymorphisms within telomerase genes and telomere length.

Campa D, Martino A, Varkonyi J, Lesueur F, Jamroziak K, Landi S, Jurczyszyn A, Marques H, Andersen V, Jurado M, Brenner H, Petrini M, Vogel U, García-Sanz R, Buda G, Gemignani F, Ríos R, Vangsted AJ, Dumontet C, Martínez-López J, Moreno MJ, Stępień A, Wątek M, Moreno V, Dieffenbach AK, Rossi AM, Butterbach K, Jacobsen SE, Goldschmidt H, Sainz J, Hillengass J, Orciuolo E, Dudziński M, Weinhold N, Reis RM, Canzian F.

Int J Cancer. 2015 Mar 1;136(5):E351-8. doi: 10.1002/ijc.29101. Epub 2014 Aug 6.

PMID:
25066524
11.

Mechanism of DNA methylation-directed histone methylation by KRYPTONITE.

Du J, Johnson LM, Groth M, Feng S, Hale CJ, Li S, Vashisht AA, Gallego-Bartolome J, Wohlschlegel JA, Patel DJ, Jacobsen SE.

Mol Cell. 2014 Aug 7;55(3):495-504. doi: 10.1016/j.molcel.2014.06.009. Epub 2014 Jul 10.

PMID:
25018018
12.

The histone variant H2A.W defines heterochromatin and promotes chromatin condensation in Arabidopsis.

Yelagandula R, Stroud H, Holec S, Zhou K, Feng S, Zhong X, Muthurajan UM, Nie X, Kawashima T, Groth M, Luger K, Jacobsen SE, Berger F.

Cell. 2014 Jul 3;158(1):98-109. doi: 10.1016/j.cell.2014.06.006.

PMID:
24995981
13.

The Functional Topography of the Arabidopsis Genome Is Organized in a Reduced Number of Linear Motifs of Chromatin States.

Sequeira-Mendes J, Aragüez I, Peiró R, Mendez-Giraldez R, Zhang X, Jacobsen SE, Bastolla U, Gutierrez C.

Plant Cell. 2014 Jun 16;26(6):2351-2366. [Epub ahead of print]

PMID:
24934173
14.

Molecular mechanism of action of plant DRM de novo DNA methyltransferases.

Zhong X, Du J, Hale CJ, Gallego-Bartolome J, Feng S, Vashisht AA, Chory J, Wohlschlegel JA, Patel DJ, Jacobsen SE.

Cell. 2014 May 22;157(5):1050-60. doi: 10.1016/j.cell.2014.03.056.

PMID:
24855943
15.

A pilot phase I dose finding safety study of the thrombopoietin-receptor agonist, eltrombopag, in patients with myelodysplastic syndrome treated with azacitidine.

Svensson T, Chowdhury O, Garelius H, Lorenz F, Saft L, Jacobsen SE, Hellström-Lindberg E, Cherif H.

Eur J Haematol. 2014 Nov;93(5):439-45. doi: 10.1111/ejh.12383. Epub 2014 Jun 14.

PMID:
24853277
16.

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

Woll PS, Kjällquist U, Chowdhury O, Doolittle H, Wedge DC, Thongjuea S, Erlandsson R, Ngara M, Anderson K, Deng Q, Mead AJ, Stenson L, Giustacchini A, Duarte S, Giannoulatou E, Taylor S, Karimi M, Scharenberg C, Mortera-Blanco T, Macaulay IC, Clark SA, Dybedal I, Josefsen D, Fenaux P, Hokland P, Holm MS, Cazzola M, Malcovati L, Tauro S, Bowen D, Boultwood J, Pellagatti A, Pimanda JE, Unnikrishnan A, Vyas P, Göhring G, Schlegelberger B, Tobiasson M, Kvalheim G, Constantinescu SN, Nerlov C, Nilsson L, Campbell PJ, Sandberg R, Papaemmanuil E, Hellström-Lindberg E, Linnarsson S, Jacobsen SE.

Cancer Cell. 2014 Jun 16;25(6):794-808. doi: 10.1016/j.ccr.2014.03.036. Epub 2014 May 15. Erratum in: Cancer Cell. 2014 Jun 16;25(6):861.

PMID:
24835589
17.

Transcriptional gene silencing by Arabidopsis microrchidia homologues involves the formation of heteromers.

Moissiard G, Bischof S, Husmann D, Pastor WA, Hale CJ, Yen L, Stroud H, Papikian A, Vashisht AA, Wohlschlegel JA, Jacobsen SE.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7474-9. doi: 10.1073/pnas.1406611111. Epub 2014 May 5.

18.

Clonal variegation and dynamic competition of leukemia-initiating cells in infant acute lymphoblastic leukemia with MLL rearrangement.

Bardini M, Woll PS, Corral L, Luc S, Wittmann L, Ma Z, Lo Nigro L, Basso G, Biondi A, Cazzaniga G, Jacobsen SE.

Leukemia. 2015 Jan;29(1):38-50. doi: 10.1038/leu.2014.154. Epub 2014 May 6.

PMID:
24798483
19.

Genetic variants and multiple myeloma risk: IMMEnSE validation of the best reported associations--an extensive replication of the associations from the candidate gene era.

Martino A, Campa D, Jurczyszyn A, Martínez-López J, Moreno MJ, Varkonyi J, Dumontet C, García-Sanz R, Gemignani F, Jamroziak K, Stępieł A, Jacobsen SE, Andersen V, Jurado M, Landi S, Rossi AM, Lesueur F, Marques H, Dudziński M, Wątek M, Moreno V, Orciuolo E, Petrini M, Reis RM, Ríos R, Sainz J, Vogel U, Buda G, Vangsted AJ, Canzian F.

Cancer Epidemiol Biomarkers Prev. 2014 Apr;23(4):670-4. doi: 10.1158/1055-9965.EPI-13-1115. Epub 2014 Feb 12.

20.

Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate.

Grover A, Mancini E, Moore S, Mead AJ, Atkinson D, Rasmussen KD, O'Carroll D, Jacobsen SE, Nerlov C.

J Exp Med. 2014 Feb 10;211(2):181-8. doi: 10.1084/jem.20131189. Epub 2014 Feb 3.

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