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Items: 1 to 20 of 146

1.

The biology, pathogenesis and clinical aspects of acute lymphoblastic leukemia in children with down syndrome.

Lee P, Bhansali R, Izraeli S, Hijiya N, Crispino JD.

Leukemia. 2016 Jun 10. doi: 10.1038/leu.2016.164. [Epub ahead of print] Review.

PMID:
27285583
2.

Molecular basis of the STIL coiled coil oligomerization explains its requirement for de-novo formation of centrosomes in mammalian cells.

David A, Amartely H, Rabinowicz N, Shamir M, Friedler A, Izraeli S.

Sci Rep. 2016 Apr 14;6:24296. doi: 10.1038/srep24296.

3.

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, Andreeff M, Armand P, Ballen KK, Barzaghi-Rinaudo P, Cahill S, Clark RA, Cooke VG, Davids MS, DeAngelo DJ, Dorfman DM, Eaton H, Ebert BL, Etchin J, Firestone B, Fisher DC, Freedman AS, Galinsky IA, Gao H, Garcia JS, Garnache-Ottou F, Graubert TA, Gutierrez A, Halilovic E, Harris MH, Herbert ZT, Horwitz SM, Inghirami G, Intlekoffer AM, Ito M, Izraeli S, Jacobsen ED, Jacobson CA, Jeay S, Jeremias I, Kelliher MA, Koch R, Konopleva M, Kopp N, Kornblau SM, Kung AL, Kupper TS, LaBoeuf N, LaCasce AS, Lees E, Li LS, Look AT, Murakami M, Muschen M, Neuberg D, Ng SY, Odejide OO, Orkin SH, Paquette RR, Place AE, Roderick JE, Ryan JA, Sallan SE, Shoji B, Silverman LB, Soiffer RJ, Steensma DP, Stegmaier K, Stone RM, Tamburini J, Thorner AR, van Hummelen P, Wadleigh M, Wiesmann M, Weng AP, Wuerthner JU, Williams DA, Wollison BM, Lane AA, Letai A, Bertagnolli MM, Ritz J, Brown M, Long H, Aster JC, Shipp MA, Griffin JD, Weinstock DM.

Cancer Cell. 2016 Apr 11;29(4):574-86. doi: 10.1016/j.ccell.2016.03.008.

PMID:
27070704
4.

On mice and humans: the role of thymic stromal lymphopoietin in human B-cell development and leukemia.

Savino AM, Izraeli S.

Haematologica. 2016 Apr;101(4):391-3. doi: 10.3324/haematol.2016.142448. No abstract available.

5.

The ability to cross the blood-cerebrospinal fluid barrier is a generic property of acute lymphoblastic leukemia blasts.

Williams MT, Yousafzai YM, Elder A, Rehe K, Bomken S, Frishman-Levy L, Tavor S, Sinclair P, Dormon K, Masic D, Perry T, Weston VJ, Kearns P, Blair H, Russell LJ, Heidenreich O, Irving JA, Izraeli S, Vormoor J, Graham GJ, Halsey C.

Blood. 2016 Apr 21;127(16):1998-2006. doi: 10.1182/blood-2015-08-665034. Epub 2016 Feb 11.

PMID:
26869395
6.

The acute lymphoblastic leukemia of Down Syndrome - Genetics and pathogenesis.

Izraeli S.

Eur J Med Genet. 2016 Mar;59(3):158-61. doi: 10.1016/j.ejmg.2015.11.010. Epub 2015 Nov 26.

PMID:
26631987
7.

Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration.

Pui CH, Yang JJ, Hunger SP, Pieters R, Schrappe M, Biondi A, Vora A, Baruchel A, Silverman LB, Schmiegelow K, Escherich G, Horibe K, Benoit YC, Izraeli S, Yeoh AE, Liang DC, Downing JR, Evans WE, Relling MV, Mullighan CG.

J Clin Oncol. 2015 Sep 20;33(27):2938-48. doi: 10.1200/JCO.2014.59.1636. Epub 2015 Aug 24. Review.

PMID:
26304874
8.

Integrated analysis of numerous heterogeneous gene expression profiles for detecting robust disease-specific biomarkers and proposing drug targets.

Amar D, Hait T, Izraeli S, Shamir R.

Nucleic Acids Res. 2015 Sep 18;43(16):7779-89. doi: 10.1093/nar/gkv810. Epub 2015 Aug 10.

9.

MagRET Nanoparticles: An Iron Oxide Nanocomposite Platform for Gene Silencing from MicroRNAs to Long Noncoding RNAs.

Lellouche E, Israel LL, Bechor M, Attal S, Kurlander E, Asher VA, Dolitzky A, Shaham L, Izraeli S, Lellouche JP, Michaeli S.

Bioconjug Chem. 2015 Aug 19;26(8):1692-701. doi: 10.1021/acs.bioconjchem.5b00276. Epub 2015 Jun 23.

PMID:
26056709
10.

Central nervous system acute lymphoblastic leukemia: role of natural killer cells.

Frishman-Levy L, Shemesh A, Bar-Sinai A, Ma C, Ni Z, Frenkel S, Muench V, Bruckmueller H, Vokuhl C, Debatin KM, Eckert C, Stanulla M, Schrappe M, Campbell KS, Loewenthal R, Schewe DM, Hochman J, Meyer LH, Kaufman D, Cario G, Porgador A, Izraeli S.

Blood. 2015 May 28;125(22):3420-31. doi: 10.1182/blood-2014-08-595108. Epub 2015 Apr 20. Erratum in: Blood. 2015 Jul 16;126(3):425.

11.

Fine tuning of surface CRLF2 expression and its associated signaling profile in childhood B-cell precursor acute lymphoblastic leukemia.

Bugarin C, Sarno J, Palmi C, Savino AM, te Kronnie G, Dworzak M, Shumich A, Buldini B, Maglia O, Sala S, Bronzini I, Bourquin JP, Mejstrikova E, Hrusak O, Luria D, Basso G, Izraeli S, Biondi A, Cazzaniga G, Gaipa G; I-BFM study group.

Haematologica. 2015 Jun;100(6):e229-32. doi: 10.3324/haematol.2014.114447. Epub 2015 Apr 10. No abstract available.

12.

MicroRNA-486-5p is an erythroid oncomiR of the myeloid leukemias of Down syndrome.

Shaham L, Vendramini E, Ge Y, Goren Y, Birger Y, Tijssen MR, McNulty M, Geron I, Schwartzman O, Goldberg L, Chou ST, Pitman H, Weiss MJ, Michaeli S, Sredni B, Göttgens B, Crispino JD, Taub JW, Izraeli S.

Blood. 2015 Feb 19;125(8):1292-301. doi: 10.1182/blood-2014-06-581892. Epub 2014 Dec 22.

13.

Lack of centrioles and primary cilia in STIL(-/-) mouse embryos.

David A, Liu F, Tibelius A, Vulprecht J, Wald D, Rothermel U, Ohana R, Seitel A, Metzger J, Ashery-Padan R, Meinzer HP, Gröne HJ, Izraeli S, Krämer A.

Cell Cycle. 2014;13(18):2859-68. doi: 10.4161/15384101.2014.946830.

14.

Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias.

Tursky ML, Beck D, Thoms JA, Huang Y, Kumari A, Unnikrishnan A, Knezevic K, Evans K, Richards LA, Lee E, Morris J, Goldberg L, Izraeli S, Wong JW, Olivier J, Lock RB, MacKenzie KL, Pimanda JE.

Leukemia. 2015 Apr;29(4):819-27. doi: 10.1038/leu.2014.299. Epub 2014 Oct 13.

PMID:
25306899
15.

Targeting oncogenic interleukin-7 receptor signalling with N-acetylcysteine in T cell acute lymphoblastic leukaemia.

Mansour MR, Reed C, Eisenberg AR, Tseng JC, Twizere JC, Daakour S, Yoda A, Rodig SJ, Tal N, Shochat C, Berezovskaya A, DeAngelo DJ, Sallan SE, Weinstock DM, Izraeli S, Kung AL, Kentsis A, Look AT.

Br J Haematol. 2015 Jan;168(2):230-8. doi: 10.1111/bjh.13115. Epub 2014 Sep 26.

16.

Haematopoietic development and leukaemia in Down syndrome.

Roberts I, Izraeli S.

Br J Haematol. 2014 Dec;167(5):587-99. doi: 10.1111/bjh.13096. Epub 2014 Aug 22. Review.

PMID:
25155832
17.

Epidemiology of childhood leukemia in the presence and absence of Down syndrome.

Mezei G, Sudan M, Izraeli S, Kheifets L.

Cancer Epidemiol. 2014 Oct;38(5):479-89. doi: 10.1016/j.canep.2014.07.006. Epub 2014 Aug 10. Review.

PMID:
25113940
18.

The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse.

Bandapalli OR, Schuessele S, Kunz JB, Rausch T, Stütz AM, Tal N, Geron I, Gershman N, Izraeli S, Eilers J, Vaezipour N, Kirschner-Schwabe R, Hof J, von Stackelberg A, Schrappe M, Stanulla M, Zimmermann M, Koehler R, Avigad S, Handgretinger R, Frismantas V, Bourquin JP, Bornhauser B, Korbel JO, Muckenthaler MU, Kulozik AE.

Haematologica. 2014 Oct;99(10):e188-92. doi: 10.3324/haematol.2014.104992. Epub 2014 Jun 27. No abstract available.

19.

miR-142 orchestrates a network of actin cytoskeleton regulators during megakaryopoiesis.

Chapnik E, Rivkin N, Mildner A, Beck G, Pasvolsky R, Metzl-Raz E, Birger Y, Amir G, Tirosh I, Porat Z, Israel LL, Lellouche E, Michaeli S, Lellouche JP, Izraeli S, Jung S, Hornstein E.

Elife. 2014 May 23;3:e01964. doi: 10.7554/eLife.01964.

20.

Beyond Philadelphia: 'Ph-like' B cell precursor acute lymphoblastic leukemias - diagnostic challenges and therapeutic promises.

Izraeli S.

Curr Opin Hematol. 2014 Jul;21(4):289-96. doi: 10.1097/MOH.0000000000000050. Review.

PMID:
24848770
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