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Results: 1 to 20 of 59

1.

Interaction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression.

Higgins J, Brogley M, Palanisamy N, Mehra R, Ittmann MM, Li JZ, Tomlins SA, Robins DM.

Horm Cancer. 2015 Jan 29. [Epub ahead of print]

PMID:
25631336
[PubMed - as supplied by publisher]
2.

GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex.

He B, Lanz RB, Fiskus W, Geng C, Yi P, Hartig SM, Rajapakshe K, Shou J, Wei L, Shah SS, Foley C, Chew SA, Eedunuri VK, Bedoya DJ, Feng Q, Minami T, Mitsiades CS, Frolov A, Weigel NL, Hilsenbeck SG, Rosen DG, Palzkill T, Ittmann MM, Song Y, Coarfa C, O'Malley BW, Mitsiades N.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18261-6. doi: 10.1073/pnas.1421415111. Epub 2014 Dec 8.

PMID:
25489091
[PubMed - in process]
3.

Stromal TGF-β signaling induces AR activation in prostate cancer.

Yang F, Chen Y, Shen T, Guo D, Dakhova O, Ittmann MM, Creighton CJ, Zhang Y, Dang TD, Rowley DR.

Oncotarget. 2014 Nov 15;5(21):10854-69.

PMID:
25333263
[PubMed - in process]
Free PMC Article
4.

Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells.

Candelaria NR, Addanki S, Zheng J, Nguyen-Vu T, Karaboga H, Dey P, Gabbi C, Vedin LL, Liu K, Wu W, Jonsson PK, Lin JZ, Su F, Bollu LR, Hodges SE, McElhany AL, Issazadeh MA, Fisher WE, Ittmann MM, Steffensen KR, Gustafsson JÅ, Lin CY.

PLoS One. 2014 Sep 3;9(9):e106289. doi: 10.1371/journal.pone.0106289. eCollection 2014.

PMID:
25184494
[PubMed - in process]
Free PMC Article
5.

Increased Notch signalling inhibits anoikis and stimulates proliferation of prostate luminal epithelial cells.

Kwon OJ, Valdez JM, Zhang L, Zhang B, Wei X, Su Q, Ittmann MM, Creighton CJ, Xin L.

Nat Commun. 2014 Jul 22;5:4416. doi: 10.1038/ncomms5416.

PMID:
25048699
[PubMed - in process]
Free PMC Article
6.

The prostate cancer TMPRSS2:ERG fusion synergizes with the vitamin D receptor (VDR) to induce CYP24A1 expression-limiting VDR signaling.

Kim JS, Roberts JM, Bingman WE 3rd, Shao L, Wang J, Ittmann MM, Weigel NL.

Endocrinology. 2014 Sep;155(9):3262-73. doi: 10.1210/en.2013-2019. Epub 2014 Jun 13.

PMID:
24926821
[PubMed - indexed for MEDLINE]
7.

Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin.

Kwon OJ, Zhang L, Ittmann MM, Xin L.

Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):E592-600. doi: 10.1073/pnas.1318157111. Epub 2013 Dec 23.

PMID:
24367088
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

FGFR1-WNT-TGF-β signaling in prostate cancer mouse models recapitulates human reactive stroma.

Carstens JL, Shahi P, Van Tsang S, Smith B, Creighton CJ, Zhang Y, Seamans A, Seethammagari M, Vedula I, Levitt JM, Ittmann MM, Rowley DR, Spencer DM.

Cancer Res. 2014 Jan 15;74(2):609-20. doi: 10.1158/0008-5472.CAN-13-1093. Epub 2013 Dec 4.

PMID:
24305876
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch.

Tennakoon JB, Shi Y, Han JJ, Tsouko E, White MA, Burns AR, Zhang A, Xia X, Ilkayeva OR, Xin L, Ittmann MM, Rick FG, Schally AV, Frigo DE.

Oncogene. 2014 Nov 6;33(45):5251-61. doi: 10.1038/onc.2013.463. Epub 2013 Nov 4.

PMID:
24186207
[PubMed - in process]
10.

ERManI is a target of miR-125b and promotes transformation phenotypes in hepatocellular carcinoma (HCC).

Pan S, Cheng X, Chen H, Castro PD, Ittmann MM, Hutson AW, Zapata SK, Sifers RN.

PLoS One. 2013 Aug 5;8(8):e72829. doi: 10.1371/journal.pone.0072829. Print 2013.

PMID:
23940818
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis.

Zhang B, Chen H, Zhang L, Dakhova O, Zhang Y, Lewis MT, Creighton CJ, Ittmann MM, Xin L.

Oncogene. 2014 Jun 12;33(24):3099-108. doi: 10.1038/onc.2013.281. Epub 2013 Jul 15.

PMID:
23851498
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

HLA-restricted NY-ESO-1 peptide immunotherapy for metastatic castration resistant prostate cancer.

Sonpavde G, Wang M, Peterson LE, Wang HY, Joe T, Mims MP, Kadmon D, Ittmann MM, Wheeler TM, Gee AP, Wang RF, Hayes TG.

Invest New Drugs. 2014 Apr;32(2):235-42. doi: 10.1007/s10637-013-9960-9. Epub 2013 Apr 23.

PMID:
23609828
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

SULT2B1b sulfotransferase: induction by vitamin D receptor and reduced expression in prostate cancer.

Seo YK, Mirkheshti N, Song CS, Kim S, Dodds S, Ahn SC, Christy B, Mendez-Meza R, Ittmann MM, Abboud-Werner S, Chatterjee B.

Mol Endocrinol. 2013 Jun;27(6):925-39. doi: 10.1210/me.2012-1369. Epub 2013 Apr 11.

PMID:
23579488
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

FGFR1 is essential for prostate cancer progression and metastasis.

Yang F, Zhang Y, Ressler SJ, Ittmann MM, Ayala GE, Dang TD, Wang F, Rowley DR.

Cancer Res. 2013 Jun 15;73(12):3716-24. doi: 10.1158/0008-5472.CAN-12-3274. Epub 2013 Apr 10.

PMID:
23576558
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

ERK and AKT signaling drive MED1 overexpression in prostate cancer in association with elevated proliferation and tumorigenicity.

Jin F, Irshad S, Yu W, Belakavadi M, Chekmareva M, Ittmann MM, Abate-Shen C, Fondell JD.

Mol Cancer Res. 2013 Jul;11(7):736-47. doi: 10.1158/1541-7786.MCR-12-0618. Epub 2013 Mar 28.

PMID:
23538858
[PubMed - indexed for MEDLINE]
Free Article
16.

Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2.

Li L, Yang G, Ren C, Tanimoto R, Hirayama T, Wang J, Hawke D, Kim SM, Lee JS, Goltsov AA, Park S, Ittmann MM, Troncoso P, Thompson TC.

Mol Oncol. 2013 Jun;7(3):484-96. doi: 10.1016/j.molonc.2012.12.005. Epub 2012 Dec 31.

PMID:
23333597
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Development and clinical validation of a real-time PCR assay for PITX2 DNA methylation to predict prostate-specific antigen recurrence in prostate cancer patients following radical prostatectomy.

Dietrich D, Hasinger O, Bañez LL, Sun L, van Leenders GJ, Wheeler TM, Bangma CH, Wernert N, Perner S, Freedland SJ, Corman JM, Ittmann MM, Lark AL, Madden JF, Hartmann A, Schatz P, Kristiansen G.

J Mol Diagn. 2013 Mar;15(2):270-9. doi: 10.1016/j.jmoldx.2012.11.002. Epub 2012 Dec 22.

PMID:
23266319
[PubMed - indexed for MEDLINE]
Free Article
18.

COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis.

Qin J, Wu SP, Creighton CJ, Dai F, Xie X, Cheng CM, Frolov A, Ayala G, Lin X, Feng XH, Ittmann MM, Tsai SJ, Tsai MJ, Tsai SY.

Nature. 2013 Jan 10;493(7431):236-40. doi: 10.1038/nature11674. Epub 2012 Nov 28.

PMID:
23201680
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Notch and TGFβ form a reciprocal positive regulatory loop that suppresses murine prostate basal stem/progenitor cell activity.

Valdez JM, Zhang L, Su Q, Dakhova O, Zhang Y, Shahi P, Spencer DM, Creighton CJ, Ittmann MM, Xin L.

Cell Stem Cell. 2012 Nov 2;11(5):676-88. doi: 10.1016/j.stem.2012.07.003.

PMID:
23122291
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis.

Shahi P, Park D, Pond AC, Seethammagari M, Chiou SH, Cho K, Carstens JL, Decker WK, McCrea PD, Ittmann MM, Rosen JM, Spencer DM.

PLoS One. 2012;7(1):e30814. doi: 10.1371/journal.pone.0030814. Epub 2012 Jan 27.

PMID:
22303459
[PubMed - indexed for MEDLINE]
Free PMC Article

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