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Results: 12

1.

Cytochrome P450 3A and P-glycoprotein drug-drug interactions with voclosporin.

Ling SY, Huizinga RB, Mayo PR, Larouche R, Freitag DG, Aspeslet LJ, Foster RT.

Br J Clin Pharmacol. 2014 Jun;77(6):1039-50. doi: 10.1111/bcp.12309.

2.

Population PKPD of voclosporin in renal allograft patients.

Mayo PR, Ling SY, Huizinga RB, Freitag DG, Aspeslet LJ, Foster RT.

J Clin Pharmacol. 2014 May;54(5):537-45. doi: 10.1002/jcph.237. Epub 2013 Nov 30.

PMID:
24243422
3.

Pharmacokinetics of voclosporin in renal impairment and hepatic impairment.

Ling SY, Huizinga RB, Mayo PR, Freitag DG, Aspeslet LJ, Foster RT.

J Clin Pharmacol. 2013 Dec;53(12):1303-12. doi: 10.1002/jcph.166. Epub 2013 Oct 8.

PMID:
23996158
4.

Voclosporin food effect and single oral ascending dose pharmacokinetic and pharmacodynamic studies in healthy human subjects.

Mayo PR, Huizinga RB, Ling SY, Freitag DG, Aspeslet LJ, Foster RT.

J Clin Pharmacol. 2013 Aug;53(8):819-26. doi: 10.1002/jcph.114. Epub 2013 Jun 4.

PMID:
23736966
5.

Development and validation of a LC/MS/MS method for quantifying the next generation calcineurin inhibitor, voclosporin, in human whole blood.

Handy R, Trepanier D, Scott G, Foster R, Freitag D.

J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Oct 15;874(1-2):57-63. doi: 10.1016/j.jchromb.2008.08.023. Epub 2008 Sep 5.

PMID:
18815080
6.

New paradigms in immunosuppression.

Huizinga R, Voyer T.

CANNT J. 2003 Jul-Sep;13(3):66-8. Review.

PMID:
14596200
7.
8.

Study of FK-binding protein: FK506-metabolite complexes by electrospray mass spectrometry: correlation to immunosuppressive activity.

Trepanier DJ, Abel MD, Freitag DG, Yatscoff RW.

Ther Drug Monit. 1999 Jun;21(3):274-80.

PMID:
10365636
9.

Clinical validation of the Helikit: a 13C urea breath test used for the diagnosis of Helicobacter pylori infection.

Mock T, Yatscoff R, Foster R, Hyun JH, Chung IS, Shim CS, Yacyshyn B.

Clin Biochem. 1999 Feb;32(1):59-63.

PMID:
10074893
10.

The monitoring of immunosuppressive drugs: a pharmacodynamic approach.

Yatscoff RW, Aspeslet LJ.

Ther Drug Monit. 1998 Oct;20(5):459-63. Review.

PMID:
9780118
11.

Rapamycin: distribution, pharmacokinetics and therapeutic range investigations: an update.

Trepanier DJ, Gallant H, Legatt DF, Yatscoff RW.

Clin Biochem. 1998 Jul;31(5):345-51. Review.

PMID:
9721433
12.

Pharmacodynamic monitoring of immunosuppressive drugs.

Yatscoff RW, Aspeslet LJ, Gallant HL.

Clin Chem. 1998 Feb;44(2):428-32.

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