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Items: 1 to 20 of 65

1.

Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.

She QB, Gruvberger-Saal SK, Maurer M, Chen Y, Jumppanen M, Su T, Dendy M, Lau YK, Memeo L, Horlings HM, van de Vijver MJ, Isola J, Hibshoosh H, Rosen N, Parsons R, Saal LH.

BMC Cancer. 2016 Aug 2;16:587. doi: 10.1186/s12885-016-2609-2.

2.

Biological subtyping of early breast cancer: a study comparing RT-qPCR with immunohistochemistry.

Wirtz RM, Sihto H, Isola J, Heikkilä P, Kellokumpu-Lehtinen PL, Auvinen P, Turpeenniemi-Hujanen T, Jyrkkiö S, Lakis S, Schlombs K, Laible M, Weber S, Eidt S, Sahin U, Joensuu H.

Breast Cancer Res Treat. 2016 Jun;157(3):437-46. doi: 10.1007/s10549-016-3835-7. Epub 2016 May 24.

3.

Quantification of Estrogen Receptor-Alpha Expression in Human Breast Carcinomas With a Miniaturized, Low-Cost Digital Microscope: A Comparison with a High-End Whole Slide-Scanner.

Holmström O, Linder N, Lundin M, Moilanen H, Suutala A, Turkki R, Joensuu H, Isola J, Diwan V, Lundin J.

PLoS One. 2015 Dec 14;10(12):e0144688. doi: 10.1371/journal.pone.0144688. eCollection 2015.

4.

Length of prostate biopsies is not necessarily compromised by pooling multiple cores in one paraffin block: an observational study.

Tolonen TT, Isola J, Kaipia A, Riikonen J, Koivusalo L, Huovinen S, Laurila M, Porre S, Tirkkonen M, Kujala P.

BMC Clin Pathol. 2015 Mar 8;15:4. doi: 10.1186/s12907-015-0001-9. eCollection 2015.

5.

Trastuzumab emtansine: mechanisms of action and drug resistance.

Barok M, Joensuu H, Isola J.

Breast Cancer Res. 2014 Mar 5;16(2):209. doi: 10.1186/bcr3621. Review.

6.

The expression patterns of gremlin 1 and noggin in normal adult and tumor tissues.

Laurila R, Parkkila S, Isola J, Kallioniemi A, Alarmo EL.

Int J Clin Exp Pathol. 2013 Jun 15;6(7):1400-8. Print 2013.

7.

Analysis of and prognostic information from disseminated tumour cells in bone marrow in primary breast cancer: a prospective observational study.

Falck AK, Bendahl PO, Ingvar C, Isola J, Jönsson PE, Lindblom P, Lövgren K, Rennstam K, Fernö M, Rydén L.

BMC Cancer. 2012 Sep 11;12:403. doi: 10.1186/1471-2407-12-403.

8.

Long-term prognosis of breast cancer detected by mammography screening or other methods.

Lehtimäki T, Lundin M, Linder N, Sihto H, Holli K, Turpeenniemi-Hujanen T, Kataja V, Isola J, Joensuu H, Lundin J.

Breast Cancer Res. 2011;13(6):R134. doi: 10.1186/bcr3080. Epub 2011 Dec 28.

9.

Characterization of non-specific cytotoxic cell receptor protein 1: a new member of the lectin-type subfamily of F-box proteins.

Kallio H, Tolvanen M, Jänis J, Pan PW, Laurila E, Kallioniemi A, Kilpinen S, Tuominen VJ, Isola J, Valjakka J, Pastorekova S, Pastorek J, Parkkila S.

PLoS One. 2011;6(11):e27152. doi: 10.1371/journal.pone.0027152. Epub 2011 Nov 7.

10.

Overall and worst gleason scores are equally good predictors of prostate cancer progression.

Tolonen TT, Kujala PM, Tammela TL, Tuominen VJ, Isola JJ, Visakorpi T.

BMC Urol. 2011 Oct 6;11:21. doi: 10.1186/1471-2490-11-21.

11.

Breast cancer biological subtypes and protein expression predict for the preferential distant metastasis sites: a nationwide cohort study.

Sihto H, Lundin J, Lundin M, Lehtimäki T, Ristimäki A, Holli K, Sailas L, Kataja V, Turpeenniemi-Hujanen T, Isola J, Heikkilä P, Joensuu H.

Breast Cancer Res. 2011 Sep 13;13(5):R87. doi: 10.1186/bcr2944.

12.

Trastuzumab-DM1 causes tumour growth inhibition by mitotic catastrophe in trastuzumab-resistant breast cancer cells in vivo.

Barok M, Tanner M, Köninki K, Isola J.

Breast Cancer Res. 2011 Apr 21;13(2):R46. doi: 10.1186/bcr2868.

13.

Development and evaluation of a virtual microscopy application for automated assessment of Ki-67 expression in breast cancer.

Konsti J, Lundin M, Joensuu H, Lehtimäki T, Sihto H, Holli K, Turpeenniemi-Hujanen T, Kataja V, Sailas L, Isola J, Lundin J.

BMC Clin Pathol. 2011 Jan 25;11:3. doi: 10.1186/1472-6890-11-3.

14.

ImmunoRatio: a publicly available web application for quantitative image analysis of estrogen receptor (ER), progesterone receptor (PR), and Ki-67.

Tuominen VJ, Ruotoistenmäki S, Viitanen A, Jumppanen M, Isola J.

Breast Cancer Res. 2010;12(4):R56. doi: 10.1186/bcr2615. Epub 2010 Jul 27.

15.

Carbonic anhydrase II. A novel biomarker for gastrointestinal stromal tumors.

Parkkila S, Lasota J, Fletcher JA, Ou WB, Kivelä AJ, Nuorva K, Parkkila AK, Ollikainen J, Sly WS, Waheed A, Pastorekova S, Pastorek J, Isola J, Miettinen M.

Mod Pathol. 2010 May;23(5):743-50. doi: 10.1038/modpathol.2009.189. Epub 2010 Jan 15.

16.

3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma.

Maurer M, Su T, Saal LH, Koujak S, Hopkins BD, Barkley CR, Wu J, Nandula S, Dutta B, Xie Y, Chin YR, Kim DI, Ferris JS, Gruvberger-Saal SK, Laakso M, Wang X, Memeo L, Rojtman A, Matos T, Yu JS, Cordon-Cardo C, Isola J, Terry MB, Toker A, Mills GB, Zhao JJ, Murty VV, Hibshoosh H, Parsons R.

Cancer Res. 2009 Aug 1;69(15):6299-306. doi: 10.1158/0008-5472.CAN-09-0820. Epub 2009 Jul 14.

17.

HER-2 positive breast cancer: decreasing proportion but stable incidence in Finnish population from 1982 to 2005.

Köninki K, Tanner M, Auvinen A, Isola J.

Breast Cancer Res. 2009;11(3):R37. doi: 10.1186/bcr2322. Epub 2009 Jun 18.

18.

Linking whole-slide microscope images with DICOM by using JPEG2000 interactive protocol.

Tuominen VJ, Isola J.

J Digit Imaging. 2010 Aug;23(4):454-62. doi: 10.1007/s10278-009-9200-1. Epub 2009 May 5.

19.

Absence of polysialylated NCAM is an unfavorable prognostic phenotype for advanced stage neuroblastoma.

Korja M, Jokilammi A, Salmi TT, Kalimo H, Pelliniemi TT, Isola J, Rantala I, Haapasalo H, Finne J.

BMC Cancer. 2009 Feb 17;9:57. doi: 10.1186/1471-2407-9-57.

20.

Web-based virtual microscopy for parasitology: a novel tool for education and quality assurance.

Linder E, Lundin M, Thors C, Lebbad M, Winiecka-Krusnell J, Helin H, Leiva B, Isola J, Lundin J.

PLoS Negl Trop Dis. 2008;2(10):e315. doi: 10.1371/journal.pntd.0000315. Epub 2008 Oct 22. Erratum in: PLoS Negl Trop Dis. 2008;2(10):10.1371/annotation/1f73ee39-9e3c-4ce4-9c35-2a6ab393de7d..

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