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Results: 1 to 20 of 45

1.

Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons.

Song Y, Zhang X, Huang L, Behlke MA, Tsourkas A.

J Vis Exp. 2014 Aug 6;(90). doi: 10.3791/51544.

PMID:
25146531
[PubMed - in process]
2.

Platelet Activating Factor Receptor Activation Improves siRNA Uptake and RNAi Responses in Well-differentiated Airway Epithelia.

Krishnamurthy S, Behlke MA, Apicella MA, McCray PB Jr, Davidson BL.

Mol Ther Nucleic Acids. 2014 Jul 15;3:e175. doi: 10.1038/mtna.2014.26.

PMID:
25025465
[PubMed]
Free PMC Article
3.

Kir3 channel ontogeny - the role of Gβγ subunits in channel assembly and trafficking.

Zylbergold P, Sleno R, Khan SM, Jacobi AM, Belhke MA, Hébert TE.

Front Cell Neurosci. 2014 Apr 14;8:108. doi: 10.3389/fncel.2014.00108. eCollection 2014.

PMID:
24782712
[PubMed]
Free PMC Article
4.

Noninvasive imaging of Staphylococcus aureus infections with a nuclease-activated probe.

Hernandez FJ, Huang L, Olson ME, Powers KM, Hernandez LI, Meyerholz DK, Thedens DR, Behlke MA, Horswill AR, McNamara JO 2nd.

Nat Med. 2014 Mar;20(3):301-6. doi: 10.1038/nm.3460. Epub 2014 Feb 2.

PMID:
24487433
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Imaging the directed transport of single engineered RNA transcripts in real-time using ratiometric bimolecular beacons.

Zhang X, Zajac AL, Huang L, Behlke MA, Tsourkas A.

PLoS One. 2014 Jan 15;9(1):e85813. doi: 10.1371/journal.pone.0085813. eCollection 2014.

PMID:
24454933
[PubMed - in process]
Free PMC Article
6.

In vivo comparison of local versus systemic delivery of immunostimulating siRNA in HPV-driven tumours.

Khairuddin N, Blake SJ, Firdaus F, Steptoe RJ, Behlke MA, Hertzog PJ, McMillan NA.

Immunol Cell Biol. 2014 Feb;92(2):156-63. doi: 10.1038/icb.2013.75. Epub 2013 Nov 12.

PMID:
24217808
[PubMed - in process]
7.

Knockdown of β-catenin with dicer-substrate siRNAs reduces liver tumor burden in vivo.

Dudek H, Wong DH, Arvan R, Shah A, Wortham K, Ying B, Diwanji R, Zhou W, Holmes B, Yang H, Cyr WA, Zhou Y, Shah A, Farkiwala R, Lee M, Li Y, Rettig GR, Collingwood MA, Basu SK, Behlke MA, Brown BD.

Mol Ther. 2014 Jan;22(1):92-101. doi: 10.1038/mt.2013.233. Epub 2013 Oct 3.

PMID:
24089139
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Improved Performance of Anti-miRNA Oligonucleotides Using a Novel Non-Nucleotide Modifier.

Lennox KA, Owczarzy R, Thomas DM, Walder JA, Behlke MA.

Mol Ther Nucleic Acids. 2013 Aug 27;2:e117. doi: 10.1038/mtna.2013.46.

PMID:
23982190
[PubMed]
Free PMC Article
9.

Quantitative assessment of ratiometric bimolecular beacons as a tool for imaging single engineered RNA transcripts and measuring gene expression in living cells.

Zhang X, Song Y, Shah AY, Lekova V, Raj A, Huang L, Behlke MA, Tsourkas A.

Nucleic Acids Res. 2013 Aug;41(15):e152. doi: 10.1093/nar/gkt561. Epub 2013 Jun 27.

PMID:
23814183
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Progress toward in vivo use of siRNAs-II.

Rettig GR, Behlke MA.

Mol Ther. 2012 Mar;20(3):483-512. doi: 10.1038/mt.2011.263. Epub 2011 Dec 20. Review.

PMID:
22186795
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Stability and mismatch discrimination of locked nucleic acid-DNA duplexes.

Owczarzy R, You Y, Groth CL, Tataurov AV.

Biochemistry. 2011 Nov 1;50(43):9352-67. doi: 10.1021/bi200904e. Epub 2011 Oct 6.

PMID:
21928795
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

RNase H-dependent PCR (rhPCR): improved specificity and single nucleotide polymorphism detection using blocked cleavable primers.

Dobosy JR, Rose SD, Beltz KR, Rupp SM, Powers KM, Behlke MA, Walder JA.

BMC Biotechnol. 2011 Aug 10;11:80. doi: 10.1186/1472-6750-11-80.

PMID:
21831278
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Chemical modification and design of anti-miRNA oligonucleotides.

Lennox KA, Behlke MA.

Gene Ther. 2011 Dec;18(12):1111-20. doi: 10.1038/gt.2011.100. Epub 2011 Jul 14. Review.

PMID:
21753793
[PubMed - indexed for MEDLINE]
14.

Measuring thermodynamic details of DNA hybridization using fluorescence.

You Y, Tataurov AV, Owczarzy R.

Biopolymers. 2011 Jul;95(7):472-86. doi: 10.1002/bip.21615. Epub 2011 Mar 7.

PMID:
21384337
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A direct comparison of anti-microRNA oligonucleotide potency.

Lennox KA, Behlke MA.

Pharm Res. 2010 Sep;27(9):1788-99. doi: 10.1007/s11095-010-0156-0. Epub 2010 Apr 28.

PMID:
20424893
[PubMed - indexed for MEDLINE]
16.

Comparing artificial neural networks, general linear models and support vector machines in building predictive models for small interfering RNAs.

McQuisten KA, Peek AS.

PLoS One. 2009 Oct 22;4(10):e7522. doi: 10.1371/journal.pone.0007522.

PMID:
19847297
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Sub-cellular trafficking and functionality of 2'-O-methyl and 2'-O-methyl-phosphorothioate molecular beacons.

Chen AK, Behlke MA, Tsourkas A.

Nucleic Acids Res. 2009 Dec;37(22):e149. doi: 10.1093/nar/gkp837. Epub .

PMID:
19820111
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Marsupial-specific microRNAs evolved from marsupial-specific transposable elements.

Devor EJ, Peek AS, Lanier W, Samollow PB.

Gene. 2009 Dec 15;448(2):187-91. doi: 10.1016/j.gene.2009.06.019. Epub 2009 Jul 3.

PMID:
19577616
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Chemical modification of siRNAs for in vivo use.

Behlke MA.

Oligonucleotides. 2008 Dec;18(4):305-19. doi: 10.1089/oli.2008.0164. Review.

PMID:
19025401
[PubMed - indexed for MEDLINE]
20.

Chemical modification patterns compatible with high potency dicer-substrate small interfering RNAs.

Collingwood MA, Rose SD, Huang L, Hillier C, Amarzguioui M, Wiiger MT, Soifer HS, Rossi JJ, Behlke MA.

Oligonucleotides. 2008 Jun;18(2):187-200. doi: 10.1089/oli.2008.0123.

PMID:
18637735
[PubMed - indexed for MEDLINE]
Free PMC Article

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