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Results: 1 to 20 of 195

1.

TDP-43 Pathology in the Population: Prevalence and Associations with Dementia and Age.

Keage HA, Hunter S, Matthews FE, Ince PG, Hodges J, Hokkanen SR, Highley JR, Dening T, Brayne C.

J Alzheimers Dis. 2014 Jan 1;42(2):641-50. doi: 10.3233/JAD-132351.

PMID:
25170584
[PubMed - in process]
2.

TDP-43 in the Population: Prevalence and Associations with Dementia and Age.

Keage HA, Hunter S, Matthews FE, Ince PG, Hodges J, Hokkanen S, Highley JR, Dening T, Brayne C.

J Alzheimers Dis. 2014 Jun 13. [Epub ahead of print]

PMID:
24927703
[PubMed - as supplied by publisher]
3.

Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions.

Cooper-Knock J, Walsh MJ, Higginbottom A, Robin Highley J, Dickman MJ, Edbauer D, Ince PG, Wharton SB, Wilson SA, Kirby J, Hautbergue GM, Shaw PJ.

Brain. 2014 Jul;137(Pt 7):2040-51. doi: 10.1093/brain/awu120. Epub 2014 May 27.

PMID:
24866055
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

DNA damage response and senescence in endothelial cells of human cerebral cortex and relation to Alzheimer's neuropathology progression: a population-based study in the MRC-CFAS cohort.

Garwood CJ, Simpson JE, Al Mashhadi S, Axe C, Wilson S, Heath PR, Shaw PJ, Matthews FE, Brayne C, Ince PG, Wharton SB; MRC Cognitive Function and Ageing Study.

Neuropathol Appl Neurobiol. 2014 May 27. doi: 10.1111/nan.12156. [Epub ahead of print]

PMID:
24861546
[PubMed - as supplied by publisher]
5.

Loss of nuclear TDP-43 in ALS causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurons.

Highley JR, Kirby J, Jansweijer JA, Webb PS, Hewamadduma CA, Heath PR, Higginbottom A, Raman R, Ferraiuolo L, Cooper-Knock J, McDermott CJ, Wharton SB, Shaw PJ, Ince PG.

Neuropathol Appl Neurobiol. 2014 Apr 18. doi: 10.1111/nan.12148. [Epub ahead of print]

PMID:
24750229
[PubMed - as supplied by publisher]
6.

PTEN regulates AMPA receptor-mediated cell viability in iPS-derived motor neurons.

Yang DJ, Wang XL, Ismail A, Ashman CJ, Valori CF, Wang G, Gao S, Higginbottom A, Ince PG, Azzouz M, Xu J, Shaw PJ, Ning K.

Cell Death Dis. 2014 Feb 27;5:e1096. doi: 10.1038/cddis.2014.55.

PMID:
24577094
[PubMed - in process]
Free PMC Article
7.

TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions.

Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, Frosch MP, Alafuzoff I, Antonell A, Bogdanovic N, Brooks W, Cairns NJ, Cooper-Knock J, Cotman C, Cras P, Cruts M, De Deyn PP, DeCarli C, Dobson-Stone C, Engelborghs S, Fox N, Galasko D, Gearing M, Gijselinck I, Grafman J, Hartikainen P, Hatanpaa KJ, Highley JR, Hodges J, Hulette C, Ince PG, Jin LW, Kirby J, Kofler J, Kril J, Kwok JB, Levey A, Lieberman A, Llado A, Martin JJ, Masliah E, McDermott CJ, McKee A, McLean C, Mead S, Miller CA, Miller J, Munoz DG, Murrell J, Paulson H, Piguet O, Rossor M, Sanchez-Valle R, Sano M, Schneider J, Silbert LC, Spina S, van der Zee J, Van Langenhove T, Warren J, Wharton SB, White CL 3rd, Woltjer RL, Trojanowski JQ, Lee VM, Van Deerlin V, Chen-Plotkin AS.

Acta Neuropathol. 2014 Mar;127(3):407-18. doi: 10.1007/s00401-013-1239-x. Epub 2014 Jan 19.

PMID:
24442578
[PubMed - in process]
Free PMC Article
8.

C9ORF72 expansions, parkinsonism, and Parkinson disease: a clinicopathologic study.

Cooper-Knock J, Frolov A, Highley JR, Charlesworth G, Kirby J, Milano A, Hartley J, Ince PG, McDermott CJ, Lashley T, Revesz T, Shaw PJ, Wood NW, Bandmann O.

Neurology. 2013 Aug 27;81(9):808-11. doi: 10.1212/WNL.0b013e3182a2cc38. Epub 2013 Jul 24.

PMID:
23884045
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The effect of SOD1 mutation on cellular bioenergetic profile and viability in response to oxidative stress and influence of mutation-type.

Richardson K, Allen SP, Mortiboys H, Grierson AJ, Wharton SB, Ince PG, Shaw PJ, Heath PR.

PLoS One. 2013 Jun 28;8(6):e68256. doi: 10.1371/journal.pone.0068256. Print 2013.

PMID:
23840839
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Brain haemosiderin in older people: pathological evidence for an ischaemic origin of magnetic resonance imaging (MRI) microbleeds.

Janaway BM, Simpson JE, Hoggard N, Highley JR, Forster G, Drew D, Gebril OH, Matthews FE, Brayne C, Wharton SB, Ince PG; MRC Cognitive Function and Ageing Neuropathology Study.

Neuropathol Appl Neurobiol. 2014 Apr;40(3):258-69. doi: 10.1111/nan.12062.

PMID:
23678850
[PubMed - in process]
11.

Consensus recommendations on pathologic changes in the hippocampus: a postmortem multicenter inter-rater study.

Rauramaa T, Pikkarainen M, Englund E, Ince PG, Jellinger K, Paetau A, Alafuzoff I.

J Neuropathol Exp Neurol. 2013 Jun;72(6):452-61. doi: 10.1097/NEN.0b013e318292492a.

PMID:
23656988
[PubMed - indexed for MEDLINE]
12.

Focal cortical dysplasia mimicking neoplasia.

Bahl A, Romanowski CA, Ince PG, McKevitt FM, Jellinek DA.

Pract Neurol. 2013 Oct;13(5):343-5. doi: 10.1136/practneurol-2012-000317. Epub 2013 Mar 15. No abstract available.

PMID:
23504031
[PubMed - indexed for MEDLINE]
13.

Calcium dysregulation in relation to Alzheimer-type pathology in the ageing brain.

Garwood C, Faizullabhoy A, Wharton SB, Ince PG, Heath PR, Shaw PJ, Baxter L, Gelsthorpe C, Forster G, Matthews FE, Brayne C, Simpson JE; MRC Cognitive Function and Ageing Neuropathology Study Group.

Neuropathol Appl Neurobiol. 2013 Dec;39(7):788-99. doi: 10.1111/nan.12033.

PMID:
23421725
[PubMed - in process]
14.

Controversies and priorities in amyotrophic lateral sclerosis.

Turner MR, Hardiman O, Benatar M, Brooks BR, Chio A, de Carvalho M, Ince PG, Lin C, Miller RG, Mitsumoto H, Nicholson G, Ravits J, Shaw PJ, Swash M, Talbot K, Traynor BJ, Van den Berg LH, Veldink JH, Vucic S, Kiernan MC.

Lancet Neurol. 2013 Mar;12(3):310-22. doi: 10.1016/S1474-4422(13)70036-X. Review.

PMID:
23415570
[PubMed - indexed for MEDLINE]
15.

Lack of unique neuropathology in amyotrophic lateral sclerosis associated with p.K54E angiogenin (ANG) mutation.

Kirby J, Highley JR, Cox L, Goodall EF, Hewitt C, Hartley JA, Hollinger HC, Fox M, Ince PG, McDermott CJ, Shaw PJ.

Neuropathol Appl Neurobiol. 2013 Aug;39(5):562-71. doi: 10.1111/nan.12007.

PMID:
23228179
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased susceptibility to excitotoxicity.

Brockington A, Ning K, Heath PR, Wood E, Kirby J, Fusi N, Lawrence N, Wharton SB, Ince PG, Shaw PJ.

Acta Neuropathol. 2013 Jan;125(1):95-109. doi: 10.1007/s00401-012-1058-5. Epub 2012 Nov 13.

PMID:
23143228
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Mesial temporal astrocyte tau pathology in the MRC-CFAS ageing brain cohort.

Lace G, Ince PG, Brayne C, Savva GM, Matthews FE, de Silva R, Simpson JE, Wharton SB.

Dement Geriatr Cogn Disord. 2012;34(1):15-24. doi: 10.1159/000341581. Epub 2012 Aug 3.

PMID:
22868294
[PubMed - indexed for MEDLINE]
18.

From molecule to clinic and community for neurodegeneration: research to bridge translational gaps.

Brayne C, Barker RA, Harold D, Ince PG, Savva GM, Williams J, Williams-Gray CH, Wharton SB.

J Alzheimers Dis. 2013;33 Suppl 1:S385-96. doi: 10.3233/JAD-2012-129006. Review.

PMID:
22647264
[PubMed - indexed for MEDLINE]
19.

Isolation of enriched glial populations from post-mortem human CNS material by immuno-laser capture microdissection.

Waller R, Woodroofe MN, Francese S, Heath PR, Wharton SB, Ince PG, Sharrack B, Simpson JE.

J Neurosci Methods. 2012 Jul 15;208(2):108-13. doi: 10.1016/j.jneumeth.2012.04.014. Epub 2012 Apr 26.

PMID:
22609336
[PubMed - indexed for MEDLINE]
20.

The neuropathology of vascular disease in the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS).

Richardson K, Stephan BC, Ince PG, Brayne C, Matthews FE, Esiri MM.

Curr Alzheimer Res. 2012 Jul;9(6):687-96.

PMID:
22471870
[PubMed - indexed for MEDLINE]

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