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Confluent hepatic fibrosis in alcohol liver cirrhosis with elevated pivkaii value - usefulness of immunostaining for EZH2 and p16INK4a in differentiating it from cholangiolocellular carcinoma - Confluent hepatic fibrosis.

Kim SK, Kim SR, Imoto S, Kim CW, Matsuoka T, Sasaki M, Nakashima O, Kumabe T, Hayashi Y.

Pathol Int. 2016 Jul 14. doi: 10.1111/pin.12435. [Epub ahead of print] No abstract available.


Gasless single-port laparoscopic-assisted vaginal hysterectomy for large uteri weighing 500g or more.

Takeda A, Hayashi S, Imoto S, Nakamura H.

Eur J Obstet Gynecol Reprod Biol. 2016 Jun 20;203:239-244. doi: 10.1016/j.ejogrb.2016.06.006. [Epub ahead of print]


Toward Extreme Biophysics: Deciphering the Infrared Response of Biomolecular Solutions at High Pressures.

Imoto S, Kibies P, Rosin C, Winter R, Kast SM, Marx D.

Angew Chem Int Ed Engl. 2016 Jun 28. doi: 10.1002/anie.201602757. [Epub ahead of print]


Iron chelating agent, Deferasirox, inhibits neutrophil activation and extracellular trap (NET) formation.

Kono M, Saigo K, Yamamoto S, Shirai K, Iwamoto S, Uematsu T, Takahashi T, Imoto S, Hashimoto M, Minami Y, Wada A, Takenokuchi M, Kawano S.

Clin Exp Pharmacol Physiol. 2016 Jun 22. doi: 10.1111/1440-1681.12612. [Epub ahead of print]


Characterization of the T cell repertoire by deep T cell receptor sequencing in tissues and blood from patients with advanced colorectal cancer.

Tamura K, Hazama S, Yamaguchi R, Imoto S, Takenouchi H, Inoue Y, Kanekiyo S, Shindo Y, Miyano S, Nakamura Y, Kiyotani K.

Oncol Lett. 2016 Jun;11(6):3643-3649. Epub 2016 Apr 19.


Reduced expression of APC-1B but not APC-1A by the deletion of promoter 1B is responsible for familial adenomatous polyposis.

Yamaguchi K, Nagayama S, Shimizu E, Komura M, Yamaguchi R, Shibuya T, Arai M, Hatakeyama S, Ikenoue T, Ueno M, Miyano S, Imoto S, Furukawa Y.

Sci Rep. 2016 May 24;6:26011. doi: 10.1038/srep26011.


A novel adaptive penalized logistic regression for uncovering biomarker associated with anti-cancer drug sensitivity.

Park H, Shiraishi Y, Imoto S, Miyano S.

IEEE/ACM Trans Comput Biol Bioinform. 2016 May 3. [Epub ahead of print]


Abnormal Corneal Lesions Induced by Trastuzumab Emtansine: An Antibody-Drug Conjugate for Breast Cancer.

Tsuda M, Takano Y, Shigeyasu C, Imoto S, Yamada M.

Cornea. 2016 May 4. [Epub ahead of print]


Characterization of T-cell Receptor Repertoire in Inflamed Tissues of Patients with Crohn's Disease Through Deep Sequencing.

Chapman CG, Yamaguchi R, Tamura K, Weidner J, Imoto S, Kwon J, Fang H, Yew PY, Marino SR, Miyano S, Nakamura Y, Kiyotani K.

Inflamm Bowel Dis. 2016 Jun;22(6):1275-85. doi: 10.1097/MIB.0000000000000752.


The hnRNP-Htt axis regulates necrotic cell death induced by transcriptional repression through impaired RNA splicing.

Mao Y, Tamura T, Yuki Y, Abe D, Tamada Y, Imoto S, Tanaka H, Homma H, Tagawa K, Miyano S, Okazawa H.

Cell Death Dis. 2016 Apr 28;7:e2207. doi: 10.1038/cddis.2016.101.


Design principles for high-pressure force fields: Aqueous TMAO solutions from ambient to kilobar pressures.

Hölzl C, Kibies P, Imoto S, Frach R, Suladze S, Winter R, Marx D, Horinek D, Kast SM.

J Chem Phys. 2016 Apr 14;144(14):144104. doi: 10.1063/1.4944991.


The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma.

Muramatsu T, Kozaki KI, Imoto S, Yamaguchi R, Tsuda H, Kawano T, Fujiwara N, Morishita M, Miyano S, Inazawa J.

Oncogene. 2016 Apr 4. doi: 10.1038/onc.2016.71. [Epub ahead of print]


Diastereoselective Synthesis of 6″-(Z)- and 6″-(E)-Fluoro Analogues of Anti-hepatitis B Virus Agent Entecavir and Its Evaluation of the Activity and Toxicity Profile of the Diastereomers.

Kumamoto H, Fukano M, Nakano T, Iwagami K, Takeyama C, Kohgo S, Imoto S, Amano M, Kuwata-Higashi N, Aoki M, Abe H, Mitsuya H, Fukuhara K, Haraguchi K.

J Org Chem. 2016 Apr 1;81(7):2827-36. doi: 10.1021/acs.joc.6b00105. Epub 2016 Mar 24.


The Difference between the Two Representative Kampo Formulas for Treating Dysmenorrhea: An Observational Study.

Yoshino T, Katayama K, Horiba Y, Munakata K, Yamaguchi R, Imoto S, Miyano S, Mima H, Watanabe K, Mimura M.

Evid Based Complement Alternat Med. 2016;2016:3159617. doi: 10.1155/2016/3159617. Epub 2016 Feb 24.


Pulmonary thromboembolism as a result of ovarian vein thrombosis after laparoscopic-assisted vaginal hysterectomy for uterine myoma.

Takeda A, Yamase Y, Koike W, Hayashi S, Imoto S, Nakamura H.

J Obstet Gynaecol Res. 2016 Jun;42(6):743-747. doi: 10.1111/jog.12973. Epub 2016 Mar 16.


Clinical significance of the expression of autophagy-associated marker, beclin 1, in breast cancer patients who received neoadjuvant endocrine therapy.

Ueno T, Saji S, Sugimoto M, Masuda N, Kuroi K, Sato N, Takei H, Yamamoto Y, Ohno S, Yamashita H, Hisamatsu K, Aogi K, Iwata H, Imoto S, Sasano H, Toi M.

BMC Cancer. 2016 Mar 16;16:230. doi: 10.1186/s12885-016-2270-9.


In-Bag Manual Extraction of Excised Myomas by Surgical Scalpel through Suprapubic Mini-Laparotomic Incision in Laparoscopic-Assisted Myomectomy.

Takeda A, Watanabe K, Hayashi S, Imoto S, Nakamura H.

J Minim Invasive Gynecol. 2016 Jul-Aug;23(5):731-8. doi: 10.1016/j.jmig.2016.02.020. Epub 2016 Mar 3.


Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.

Kato T, Inoue H, Imoto S, Tamada Y, Miyamoto T, Matsuo Y, Nakamura Y, Park JH.

Oncotarget. 2016 Apr 5;7(14):17652-64. doi: 10.18632/oncotarget.7755.


Prognostic factors in patients with vulvar cancer treated with primary surgery: a single-center experience.

Imoto S, Inamine M, Kudaka W, Nagai Y, Wakayama A, Nakamoto T, Ooyama T, Aoki Y.

Springerplus. 2016 Feb 18;5:125. doi: 10.1186/s40064-016-1767-7. eCollection 2016.


One-step nucleic acid amplification assay for intraoperative prediction of advanced axillary lymph node metastases in breast cancer patients with sentinel lymph node metastasis.

Kubota M, Komoike Y, Hamada M, Shinzaki W, Azumi T, Hashimoto Y, Imoto S, Takeyama Y, Okuno K.

Mol Clin Oncol. 2016 Feb;4(2):173-178. Epub 2015 Dec 7.

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