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Results: 1 to 20 of 419

1.

Associations between thyroid hormones and serum metabolite profiles in an euthyroid population.

Jourdan C, Linseisen J, Meisinger C, Petersen AK, Gieger C, Rawal R, Illig T, Heier M, Peters A, Wallaschofski H, Nauck M, Kastenmüller G, Suhre K, Prehn C, Adamski J, Koenig W, Roden M, Wichmann HE, Völzke H.

Metabolomics. 2014;10:152-164. Epub 2013 Jul 18.

PMID:
24955082
[PubMed]
Free PMC Article
2.

Fine-mapping of IgE-associated loci 1q23, 5q31, and 12q13 using 1000 Genomes Project data.

Sharma V, Michel S, Gaertner V, Franke A, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Frischer T, Genuneit J, Zeilinger S, Illig T, Schedel M, Potaczek DP, Kabesch M.

Allergy. 2014 Aug;69(8):1077-84. doi: 10.1111/all.12431. Epub 2014 Jun 14.

PMID:
24930997
[PubMed - in process]
3.

Novel genetic associations with serum level metabolites identified by phenotype set enrichment analyses.

Ried JS, Shin SY, Krumsiek J, Illig T, Theis FJ, Spector TD, Adamski J, Wichmann HE, Strauch K, Soranzo N, Suhre K, Gieger C.

Hum Mol Genet. 2014 Jun 13. pii: ddu301. [Epub ahead of print]

PMID:
24927737
[PubMed - as supplied by publisher]
4.

Antioxidant defense enzyme genes and asthma susceptibility: gender-specific effects and heterogeneity in gene-gene interactions between pathogenetic variants of the disease.

Polonikov AV, Ivanov VP, Bogomazov AD, Freidin MB, Illig T, Solodilova MA.

Biomed Res Int. 2014;2014:708903. doi: 10.1155/2014/708903. Epub 2014 May 5.

PMID:
24895604
[PubMed - in process]
Free PMC Article
5.

PLA1A2 platelet polymorphism predicts mortality in prediabetic subjects of the population based KORA S4-Cohort.

Stratmann B, Xu T, Meisinger C, Menart B, Roden M, Herder C, Grallert H, Peters A, Koenig W, Illig T, Wichmann HE, Wang-Sattler R, Rathmann W, Tschoepe D.

Cardiovasc Diabetol. 2014 May 5;13:90. doi: 10.1186/1475-2840-13-90.

PMID:
24886443
[PubMed - in process]
Free PMC Article
6.

Blood cis-eQTL analysis fails to identify novel association signals among sub-threshold candidates from genome-wide association studies in restless legs syndrome.

Schulte EC, Schramm K, Schurmann C, Lichtner P, Herder C, Roden M, Gieger C, Peters A, Trenkwalder C, Högl B, Frauscher B, Berger K, Fietze I, Gross N, Stiasny-Kolster K, Oertel W, Bachmann CG, Paulus W, Zimprich A, Völzke H, Schminke U, Nauck M, Illig T, Meitinger T, Müller-Myhsok B, Prokisch H, Winkelmann J.

PLoS One. 2014 May 29;9(5):e98092. doi: 10.1371/journal.pone.0098092. eCollection 2014.

PMID:
24875634
[PubMed - in process]
Free PMC Article
7.

Metabolomics approach reveals effects of antihypertensives and lipid-lowering drugs on the human metabolism.

Altmaier E, Fobo G, Heier M, Thorand B, Meisinger C, Römisch-Margl W, Waldenberger M, Gieger C, Illig T, Adamski J, Suhre K, Kastenmüller G.

Eur J Epidemiol. 2014 May;29(5):325-36. doi: 10.1007/s10654-014-9910-7. Epub 2014 May 10.

PMID:
24816436
[PubMed - in process]
Free PMC Article
8.

Mitochondrial DNA variants in obesity.

Knoll N, Jarick I, Volckmar AL, Klingenspor M, Illig T, Grallert H, Gieger C, Wichmann HE, Peters A, Wiegand S, Biebermann H, Fischer-Posovszky P, Wabitsch M, Völzke H, Nauck M, Teumer A, Rosskopf D, Rimmbach C, Schreiber S, Jacobs G, Lieb W, Franke A, Hebebrand J, Hinney A.

PLoS One. 2014 May 2;9(5):e94882. doi: 10.1371/journal.pone.0094882. eCollection 2014.

PMID:
24788344
[PubMed - in process]
Free PMC Article
9.

Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome: the cardiovascular risk in Young Finns Study.

Raitoharju E, Seppälä I, Oksala N, Lyytikäinen LP, Raitakari O, Viikari J, Ala-Korpela M, Soininen P, Kangas AJ, Waldenberger M, Klopp N, Illig T, Leiviskä J, Loo BM, Hutri-Kähönen N, Kähönen M, Laaksonen R, Lehtimäki T.

Mol Cell Endocrinol. 2014 Jun 25;391(1-2):41-9. doi: 10.1016/j.mce.2014.04.013. Epub 2014 Apr 28.

PMID:
24784704
[PubMed - in process]
10.

Changes in metabolite profiles caused by genetically determined obesity in mice.

Schäfer N, Yu Z, Wagener A, Millrose MK, Reissmann M, Bortfeldt R, Dieterich C, Adamski J, Wang-Sattler R, Illig T, Brockmann GA.

Metabolomics. 2014;10:461-472. Epub 2013 Oct 19.

PMID:
24772056
[PubMed]
Free PMC Article
11.

Changes in the serum metabolite profile in obese children with weight loss.

Reinehr T, Wolters B, Knop C, Lass N, Hellmuth C, Harder U, Peissner W, Wahl S, Grallert H, Adamski J, Illig T, Prehn C, Yu Z, Wang-Sattler R, Koletzko B.

Eur J Nutr. 2014 Apr 17. [Epub ahead of print]

PMID:
24740590
[PubMed - as supplied by publisher]
12.

Mapping the genetic architecture of gene regulation in whole blood.

Schramm K, Marzi C, Schurmann C, Carstensen M, Reinmaa E, Biffar R, Eckstein G, Gieger C, Grabe HJ, Homuth G, Kastenmüller G, Mägi R, Metspalu A, Mihailov E, Peters A, Petersmann A, Roden M, Strauch K, Suhre K, Teumer A, Völker U, Völzke H, Wang-Sattler R, Waldenberger M, Meitinger T, Illig T, Herder C, Grallert H, Prokisch H.

PLoS One. 2014 Apr 16;9(4):e93844. doi: 10.1371/journal.pone.0093844. eCollection 2014.

PMID:
24740359
[PubMed - in process]
Free PMC Article
13.

An integrated epigenetic and transcriptomic analysis reveals distinct tissue-specific patterns of DNA methylation associated with atopic dermatitis.

Rodríguez E, Baurecht H, Wahn AF, Kretschmer A, Hotze M, Zeilinger S, Klopp N, Illig T, Schramm K, Prokisch H, Kühnel B, Gieger C, Harder J, Cifuentes L, Novak N, Weidinger S.

J Invest Dermatol. 2014 Jul;134(7):1873-83. doi: 10.1038/jid.2014.87. Epub 2014 Feb 13.

PMID:
24739813
[PubMed - in process]
14.

Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein metabolism in women and USF1 expression in atherosclerotic plaque.

Fan YM, Hernesniemi J, Oksala N, Levula M, Raitoharju E, Collings A, Hutri-Kähönen N, Juonala M, Marniemi J, Lyytikäinen LP, Seppälä I, Mennander A, Tarkka M, Kangas AJ, Soininen P, Salenius JP, Klopp N, Illig T, Laitinen T, Ala-Korpela M, Laaksonen R, Viikari J, Kähönen M, Raitakari OT, Lehtimäki T.

Sci Rep. 2014 Apr 11;4:4650. doi: 10.1038/srep04650.

PMID:
24722012
[PubMed - in process]
Free PMC Article
15.

Increased amino acids levels and the risk of developing of hypertriglyceridemia in a 7-year follow-up.

Mook-Kanamori DO, Römisch-Margl W, Kastenmüller G, Prehn C, Petersen AK, Illig T, Gieger C, Wang-Sattler R, Meisinger C, Peters A, Adamski J, Suhre K.

J Endocrinol Invest. 2014 Jan 9. [Epub ahead of print]

PMID:
24682914
[PubMed - as supplied by publisher]
Free PMC Article
16.

Interrogating causal pathways linking genetic variants, small molecule metabolites and circulating lipids.

Shin SY, Petersen AK, Wahl S, Zhai G, Römisch-Margl W, Small KS, Döring A, Kato BS, Peters A, Grundberg E, Prehn C, Wang-Sattler R, Wichmann HE, Hrabé de Angelis M, Illig T, Adamski J, Deloukas P, Spector TD, Suhre K, Gieger C, Soranzo N.

Genome Med. 2014 Mar 28;6(3):25. [Epub ahead of print]

PMID:
24678845
[PubMed - as supplied by publisher]
Free PMC Article
17.

Genetic factors in individual radiation sensitivity.

Hornhardt S, Rößler U, Sauter W, Rosenberger A, Illig T, Bickeböller H, Wichmann HE, Gomolka M.

DNA Repair (Amst). 2014 Apr;16:54-65. doi: 10.1016/j.dnarep.2014.02.001. Epub 2014 Mar 4.

PMID:
24674628
[PubMed - in process]
18.

A common atopy-associated variant in the Th2 cytokine locus control region impacts transcriptional regulation and alters SMAD3 and SP1 binding.

Kretschmer A, Möller G, Lee H, Laumen H, von Toerne C, Schramm K, Prokisch H, Eyerich S, Wahl S, Baurecht H, Franke A, Claussnitzer M, Eyerich K, Teumer A, Milani L, Klopp N, Hauck SM, Illig T, Peters A, Waldenberger M, Adamski J, Reischl E, Weidinger S.

Allergy. 2014 May;69(5):632-42. doi: 10.1111/all.12394. Epub 2014 Mar 25.

PMID:
24661001
[PubMed - in process]
19.

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci.

Tragante V, Barnes MR, Ganesh SK, Lanktree MB, Guo W, Franceschini N, Smith EN, Johnson T, Holmes MV, Padmanabhan S, Karczewski KJ, Almoguera B, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Gaunt TR, Gho JM, Gieger C, Goel A, Gong Y, Isaacs A, Kleber ME, Mateo Leach I, McDonough CW, Meijs MF, Melander O, Nelson CP, Nolte IM, Pankratz N, Price TS, Shaffer J, Shah S, Tomaszewski M, van der Most PJ, Van Iperen EP, Vonk JM, Witkowska K, Wong CO, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Brown M, Burt A, Cooper-DeHoff RM, Connell JM, Cruickshanks KJ, Curtis SP, Davey-Smith G, Delles C, Gansevoort RT, Guo X, Haiqing S, Hastie CE, Hofker MH, Hovingh GK, Kim DS, Kirkland SA, Klein BE, Klein R, Li YR, Maiwald S, Newton-Cheh C, O'Brien ET, Onland-Moret NC, Palmas W, Parsa A, Penninx BW, Pettinger M, Vasan RS, Ranchalis JE, M Ridker P, Rose LM, Sever P, Shimbo D, Steele L, Stolk RP, Thorand B, Trip MD, van Duijn CM, Verschuren WM, Wijmenga C, Wyatt S, Young JH, Zwinderman AH, Bezzina CR, Boerwinkle E, Casas JP, Caulfield MJ, Chakravarti A, Chasman DI, Davidson KW, Doevendans PA, Dominiczak AF, FitzGerald GA, Gums JG, Fornage M, Hakonarson H, Halder I, Hillege HL, Illig T, Jarvik GP, Johnson JA, Kastelein JJ, Koenig W, Kumari M, März W, Murray SS, O'Connell JR, Oldehinkel AJ, Pankow JS, Rader DJ, Redline S, Reilly MP, Schadt EE, Kottke-Marchant K, Snieder H, Snyder M, Stanton AV, Tobin MD, Uitterlinden AG, van der Harst P, van der Schouw YT, Samani NJ, Watkins H, Johnson AD, Reiner AP, Zhu X, de Bakker PI, Levy D, Asselbergs FW, Munroe PB, Keating BJ.

Am J Hum Genet. 2014 Mar 6;94(3):349-60. doi: 10.1016/j.ajhg.2013.12.016. Epub 2014 Feb 20.

PMID:
24560520
[PubMed - indexed for MEDLINE]
20.

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium; Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium; South Asian Type 2 Diabetes (SAT2D) Consortium; Mexican American Type 2 Diabetes (MAT2D) Consortium; Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium, Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, Saleheen D, Wang X, Zeggini E, Abecasis GR, Adair LS, Almgren P, Atalay M, Aung T, Baldassarre D, Balkau B, Bao Y, Barnett AH, Barroso I, Basit A, Been LF, Beilby J, Bell GI, Benediktsson R, Bergman RN, Boehm BO, Boerwinkle E, Bonnycastle LL, Burtt N, Cai Q, Campbell H, Carey J, Cauchi S, Caulfield M, Chan JC, Chang LC, Chang TJ, Chang YC, Charpentier G, Chen CH, Chen H, Chen YT, Chia KS, Chidambaram M, Chines PS, Cho NH, Cho YM, Chuang LM, Collins FS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Danesh J, Das D, de Faire U, Dedoussis G, Deloukas P, Dimas AS, Dina C, Doney AS, Donnelly PJ, Dorkhan M, van Duijn C, Dupuis J, Edkins S, Elliott P, Emilsson V, Erbel R, Eriksson JG, Escobedo J, Esko T, Eury E, Florez JC, Fontanillas P, Forouhi NG, Forsen T, Fox C, Fraser RM, Frayling TM, Froguel P, Frossard P, Gao Y, Gertow K, Gieger C, Gigante B, Grallert H, Grant GB, Grrop LC, Groves CJ, Grundberg E, Guiducci C, Hamsten A, Han BG, Hara K, Hassanali N, Hattersley AT, Hayward C, Hedman AK, Herder C, Hofman A, Holmen OL, Hovingh K, Hreidarsson AB, Hu C, Hu FB, Hui J, Humphries SE, Hunt SE, Hunter DJ, Hveem K, Hydrie ZI, Ikegami H, Illig T, Ingelsson E, Islam M, Isomaa B, Jackson AU, Jafar T, James A, Jia W, Jöckel KH, Jonsson A, Jowett JB, Kadowaki T, Kang HM, Kanoni S, Kao WH, Kathiresan S, Kato N, Katulanda P, Keinanen-Kiukaanniemi KM, Kelly AM, Khan H, Khaw KT, Khor CC, Kim HL, Kim S, Kim YJ, Kinnunen L, Klopp N, Kong A, Korpi-Hyövälti E, Kowlessur S, Kraft P, Kravic J, Kristensen MM, Krithika S, Kumar A, Kumate J, Kuusisto J, Kwak SH, Laakso M, Lagou V, Lakka TA, Langenberg C, Langford C, Lawrence R, Leander K, Lee JM, Lee NR, Li M, Li X, Li Y, Liang J, Liju S, Lim WY, Lind L, Lindgren CM, Lindholm E, Liu CT, Liu JJ, Lobbens S, Long J, Loos RJ, Lu W, Luan J, Lyssenko V, Ma RC, Maeda S, Mägi R, Männisto S, Matthews DR, Meigs JB, Melander O, Metspalu A, Meyer J, Mirza G, Mihailov E, Moebus S, Mohan V, Mohlke KL, Morris AD, Mühleisen TW, Müller-Nurasyid M, Musk B, Nakamura J, Nakashima E, Navarro P, Ng PK, Nica AC, Nilsson PM, Njølstad I, Nöthen MM, Ohnaka K, Ong TH, Owen KR, Palmer CN, Pankow JS, Park KS, Parkin M, Pechlivanis S, Pedersen NL, Peltonen L, Perry JR, Peters A, Pinidiyapathirage JM, Platou CG, Potter S, Price JF, Qi L, Radha V, Rallidis L, Rasheed A, Rathman W, Rauramaa R, Raychaudhuri S, Rayner NW, Rees SD, Rehnberg E, Ripatti S, Robertson N, Roden M, Rossin EJ, Rudan I, Rybin D, Saaristo TE, Salomaa V, Saltevo J, Samuel M, Sanghera DK, Saramies J, Scott J, Scott LJ, Scott RA, Segrè AV, Sehmi J, Sennblad B, Shah N, Shah S, Shera AS, Shu XO, Shuldiner AR, Sigurđsson G, Sijbrands E, Silveira A, Sim X, Sivapalaratnam S, Small KS, So WY, Stančáková A, Stefansson K, Steinbach G, Steinthorsdottir V, Stirrups K, Strawbridge RJ, Stringham HM, Sun Q, Suo C, Syvänen AC, Takayanagi R, Takeuchi F, Tay WT, Teslovich TM, Thorand B, Thorleifsson G, Thorsteinsdottir U, Tikkanen E, Trakalo J, Tremoli E, Trip MD, Tsai FJ, Tuomi T, Tuomilehto J, Uitterlinden AG, Valladares-Salgado A, Vedantam S, Veglia F, Voight BF, Wang C, Wareham NJ, Wennauer R, Wickremasinghe AR, Wilsgaard T, Wilson JF, Wiltshire S, Winckler W, Wong TY, Wood AR, Wu JY, Wu Y, Yamamoto K, Yamauchi T, Yang M, Yengo L, Yokota M, Young R, Zabaneh D, Zhang F, Zhang R, Zheng W, Zimmet PZ, Altshuler D, Bowden DW, Cho YS, Cox NJ, Cruz M, Hanis CL, Kooner J, Lee JY, Seielstad M, Teo YY, Boehnke M, Parra EJ, Chambers JC, Tai ES, McCarthy MI, Morris AP.

Nat Genet. 2014 Mar;46(3):234-44. doi: 10.1038/ng.2897. Epub 2014 Feb 9.

PMID:
24509480
[PubMed - indexed for MEDLINE]

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