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Results: 1 to 20 of 88

1.

Adverse outcome pathway development II: best practices.

Villeneuve DL, Crump D, Garcia-Reyero N, Hecker M, Hutchinson TH, LaLone CA, Landesmann B, Lettieri T, Munn S, Nepelska M, Ottinger MA, Vergauwen L, Whelan M.

Toxicol Sci. 2014 Dec;142(2):321-30. doi: 10.1093/toxsci/kfu200.

PMID:
25466379
2.

Adverse outcome pathway (AOP) development I: strategies and principles.

Villeneuve DL, Crump D, Garcia-Reyero N, Hecker M, Hutchinson TH, LaLone CA, Landesmann B, Lettieri T, Munn S, Nepelska M, Ottinger MA, Vergauwen L, Whelan M.

Toxicol Sci. 2014 Dec;142(2):312-20. doi: 10.1093/toxsci/kfu199.

PMID:
25466378
3.

Comparative metabolism as a key driver of wildlife species sensitivity to human and veterinary pharmaceuticals.

Hutchinson TH, Madden JC, Naidoo V, Walker CH.

Philos Trans R Soc Lond B Biol Sci. 2014 Nov 19;369(1656). pii: 20130583. doi: 10.1098/rstb.2013.0583.

PMID:
25405970
4.

Sources, impacts and trends of pharmaceuticals in the marine and coastal environment.

Gaw S, Thomas KV, Hutchinson TH.

Philos Trans R Soc Lond B Biol Sci. 2014 Nov 19;369(1656). pii: 20130572. doi: 10.1098/rstb.2013.0572.

PMID:
25405962
5.

Juvenile king scallop, Pecten maximus, is potentially tolerant to low levels of ocean acidification when food is unrestricted.

Sanders MB, Bean TP, Hutchinson TH, Le Quesne WJ.

PLoS One. 2013 Sep 4;8(9):e74118. doi: 10.1371/journal.pone.0074118. eCollection 2013.

6.

Evaluating legacy contaminants and emerging chemicals in marine environments using adverse outcome pathways and biological effects-directed analysis.

Hutchinson TH, Lyons BP, Thain JE, Law RJ.

Mar Pollut Bull. 2013 Sep 30;74(2):517-25. doi: 10.1016/j.marpolbul.2013.06.012. Epub 2013 Jun 29.

PMID:
23820191
7.

Assessing the exposure risk and impacts of pharmaceuticals in the environment on individuals and ecosystems.

Arnold KE, Boxall AB, Brown AR, Cuthbert RJ, Gaw S, Hutchinson TH, Jobling S, Madden JC, Metcalfe CD, Naidoo V, Shore RF, Smits JE, Taggart MA, Thompson HM.

Biol Lett. 2013 Jun 26;9(4):20130492. doi: 10.1098/rsbl.2013.0492. Print 2013 Aug 23.

8.

Metabolism of ibuprofen in zebrafish larvae.

Jones HS, Trollope HT, Hutchinson TH, Panter GH, Chipman JK.

Xenobiotica. 2012 Nov;42(11):1069-75. doi: 10.3109/00498254.2012.684410. Epub 2012 May 17.

PMID:
22594345
9.

Interference with xenobiotic metabolic activity by the commonly used vehicle solvents dimethylsulfoxide and methanol in zebrafish (Danio rerio) larvae but not Daphnia magna.

David RM, Jones HS, Panter GH, Winter MJ, Hutchinson TH, Kevin Chipman J.

Chemosphere. 2012 Aug;88(8):912-7. doi: 10.1016/j.chemosphere.2012.03.018. Epub 2012 Apr 1.

10.

Characterisation and expression of β1-, β2- and β3-adrenergic receptors in the fathead minnow (Pimephales promelas).

Giltrow E, Eccles PD, Hutchinson TH, Sumpter JP, Rand-Weaver M.

Gen Comp Endocrinol. 2011 Sep 15;173(3):483-90. doi: 10.1016/j.ygcen.2011.07.006. Epub 2011 Jul 31.

PMID:
21827763
11.

Influence of a collapsed coastal landfill on metal levels in sediments and biota--a portent for the future?

Pope ND, O'Hara SC, Imamura M, Hutchinson TH, Langston WJ.

J Environ Monit. 2011 Jul;13(7):1961-74. doi: 10.1039/c0em00741b. Epub 2011 May 19.

PMID:
21597644
12.

Immunological function in marine invertebrates: responses to environmental perturbation.

Ellis RP, Parry H, Spicer JI, Hutchinson TH, Pipe RK, Widdicombe S.

Fish Shellfish Immunol. 2011 Jun;30(6):1209-22. doi: 10.1016/j.fsi.2011.03.017. Epub 2011 Apr 2. Review.

PMID:
21463691
13.

In vivo and in vitro liver and gill EROD activity in rainbow trout (Oncorhynchus mykiss) exposed to the beta-blocker propranolol.

Bartram AE, Winter MJ, Huggett DB, McCormack P, Constantine LA, Hetheridge MJ, Hutchinson TH, Kinter LB, Ericson JF, Sumpter JP, Owen SF.

Environ Toxicol. 2012 Oct;27(10):573-82. doi: 10.1002/tox.20684. Epub 2011 Mar 7.

PMID:
21384489
14.

Species extrapolation for the 21st century.

Celander MC, Goldstone JV, Denslow ND, Iguchi T, Kille P, Meyerhoff RD, Smith BA, Hutchinson TH, Wheeler JR.

Environ Toxicol Chem. 2011 Jan;30(1):52-63. doi: 10.1002/etc.382.

PMID:
20963850
15.

The value of repeating studies and multiple controls: replicated 28-day growth studies of rainbow trout exposed to clofibric acid.

Owen SF, Huggett DB, Hutchinson TH, Hetheridge MJ, McCormack P, Kinter LB, Ericson JF, Constantine LA, Sumpter JP.

Environ Toxicol Chem. 2010 Dec;29(12):2831-9. doi: 10.1002/etc.351. Epub 2010 Oct 23.

PMID:
20836071
16.

Challenging the requirement for chronic fish toxicity studies on formulated plant protection products.

Creton S, Douglas M, Wheeler JR, Hutchinson TH.

Toxicol Lett. 2010 Nov 30;199(2):111-4. doi: 10.1016/j.toxlet.2010.08.019. Epub 2010 Sep 8. Review.

PMID:
20832457
17.

Oxidative and conjugative xenobiotic metabolism in zebrafish larvae in vivo.

Jones HS, Panter GH, Hutchinson TH, Chipman JK.

Zebrafish. 2010 Mar;7(1):23-30. doi: 10.1089/zeb.2009.0630.

PMID:
20415643
18.

A proteomics based approach to assessing the toxicity of bisphenol A and diallyl phthalate to the abalone (Haliotis diversicolor supertexta).

Zhou J, Cai ZH, Li L, Gao YF, Hutchinson TH.

Chemosphere. 2010 Apr;79(5):595-604. doi: 10.1016/j.chemosphere.2010.01.052. Epub 2010 Mar 1.

PMID:
20189630
19.

Pyrosequencing of Mytilus galloprovincialis cDNAs: tissue-specific expression patterns.

Craft JA, Gilbert JA, Temperton B, Dempsey KE, Ashelford K, Tiwari B, Hutchinson TH, Chipman JK.

PLoS One. 2010 Jan 25;5(1):e8875. doi: 10.1371/journal.pone.0008875.

20.

Effects of a weak oestrogenic active chemical (4-tert-pentylphenol) on pair-breeding and F1 development in the fathead minnow (Pimephales promelas).

Panter GH, Hutchinson TH, Hurd KS, Bamforth J, Stanley RD, Wheeler JR, Tyler CR.

Aquat Toxicol. 2010 May 10;97(4):314-23. doi: 10.1016/j.aquatox.2009.12.019. Epub 2010 Jan 4.

PMID:
20106537
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