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Items: 1 to 20 of 43

1.

Cosmid based mutagenesis causes genetic instability in Streptomyces coelicolor, as shown by targeting of the lipoprotein signal peptidase gene.

Munnoch JT, Widdick DA, Chandra G, Sutcliffe IC, Palmer T, Hutchings MI.

Sci Rep. 2016 Jul 12;6:29495. doi: 10.1038/srep29495.

2.

Differentiated, Promoter-specific Response of [4Fe-4S] NsrR DNA Binding to Reaction with Nitric Oxide.

Crack JC, Svistunenko DA, Munnoch J, Thomson AJ, Hutchings MI, Le Brun NE.

J Biol Chem. 2016 Apr 15;291(16):8663-72. doi: 10.1074/jbc.M115.693192. Epub 2016 Feb 17.

3.

Biochemical properties of Paracoccus denitrificans FnrP: reactions with molecular oxygen and nitric oxide.

Crack JC, Hutchings MI, Thomson AJ, Le Brun NE.

J Biol Inorg Chem. 2016 Mar;21(1):71-82. doi: 10.1007/s00775-015-1326-7. Epub 2016 Jan 20.

PMID:
26790880
Free PMC Article
4.

NsrR from Streptomyces coelicolor is a nitric oxide-sensing [4Fe-4S] cluster protein with a specialized regulatory function.

Crack JC, Munnoch J, Dodd EL, Knowles F, Al Bassam MM, Kamali S, Holland AA, Cramer SP, Hamilton CJ, Johnson MK, Thomson AJ, Hutchings MI, Le Brun NE.

J Biol Chem. 2015 May 15;290(20):12689-704. doi: 10.1074/jbc.M115.643072. Epub 2015 Mar 14.

5.

Regulation of antimycin biosynthesis by the orphan ECF RNA polymerase sigma factor σ (AntA.).

Seipke RF, Patrick E, Hutchings MI.

PeerJ. 2014 Feb 6;2:e253. doi: 10.7717/peerj.253. eCollection 2014.

6.

The regulation and biosynthesis of antimycins.

Seipke RF, Hutchings MI.

Beilstein J Org Chem. 2013 Nov 19;9:2556-63. doi: 10.3762/bjoc.9.290. Review.

7.

Analysis of the bacterial communities associated with two ant-plant symbioses.

Seipke RF, Barke J, Heavens D, Yu DW, Hutchings MI.

Microbiologyopen. 2013 Apr;2(2):276-83. doi: 10.1002/mbo3.73. Epub 2013 Feb 17.

8.

Mammalian cell entry genes in Streptomyces may provide clues to the evolution of bacterial virulence.

Clark LC, Seipke RF, Prieto P, Willemse J, van Wezel GP, Hutchings MI, Hoskisson PA.

Sci Rep. 2013;3:1109. doi: 10.1038/srep01109. Epub 2013 Jan 23.

9.

Use and discovery of chemical elicitors that stimulate biosynthetic gene clusters in Streptomyces bacteria.

Moore JM, Bradshaw E, Seipke RF, Hutchings MI, McArthur M.

Methods Enzymol. 2012;517:367-85. doi: 10.1016/B978-0-12-404634-4.00018-8.

PMID:
23084948
10.

Isolating antifungals from fungus-growing ant symbionts using a genome-guided chemistry approach.

Seipke RF, Grüschow S, Goss RJ, Hutchings MI.

Methods Enzymol. 2012;517:47-70. doi: 10.1016/B978-0-12-404634-4.00003-6.

PMID:
23084933
11.

Dynamic localization of Tat protein transport machinery components in Streptomyces coelicolor.

Willemse J, Ruban-Ośmialowska B, Widdick D, Celler K, Hutchings MI, van Wezel GP, Palmer T.

J Bacteriol. 2012 Nov;194(22):6272-81. doi: 10.1128/JB.01425-12. Epub 2012 Sep 21.

12.

A phylum level analysis reveals lipoprotein biosynthesis to be a fundamental property of bacteria.

Sutcliffe IC, Harrington DJ, Hutchings MI.

Protein Cell. 2012 Mar;3(3):163-70. doi: 10.1007/s13238-012-2023-8. Review.

13.

Bacterial iron-sulfur regulatory proteins as biological sensor-switches.

Crack JC, Green J, Hutchings MI, Thomson AJ, Le Brun NE.

Antioxid Redox Signal. 2012 Nov 1;17(9):1215-31. doi: 10.1089/ars.2012.4511. Epub 2012 Mar 6. Review.

14.

Streptomyces as symbionts: an emerging and widespread theme?

Seipke RF, Kaltenpoth M, Hutchings MI.

FEMS Microbiol Rev. 2012 Jul;36(4):862-76. doi: 10.1111/j.1574-6976.2011.00313.x. Epub 2011 Dec 2. Review.

15.

Spectroscopic analysis of protein Fe-NO complexes.

Bellota-Antón C, Munnoch J, Robb K, Adamczyk K, Candelaresi M, Parker AW, Dixon R, Hutchings MI, Hunt NT, Tucker NP.

Biochem Soc Trans. 2011 Oct;39(5):1293-8. doi: 10.1042/BST0391293. Review.

PMID:
21936804
16.

A single Streptomyces symbiont makes multiple antifungals to support the fungus farming ant Acromyrmex octospinosus.

Seipke RF, Barke J, Brearley C, Hill L, Yu DW, Goss RJ, Hutchings MI.

PLoS One. 2011;6(8):e22028. doi: 10.1371/journal.pone.0022028. Epub 2011 Aug 3.

17.

Fungus-growing Allomerus ants are associated with antibiotic-producing actinobacteria.

Seipke RF, Barke J, Ruiz-Gonzalez MX, Orivel J, Yu DW, Hutchings MI.

Antonie Van Leeuwenhoek. 2012 Feb;101(2):443-7. doi: 10.1007/s10482-011-9621-y. Epub 2011 Jul 12.

PMID:
21748399
18.

Draft genome sequence of Streptomyces strain S4, a symbiont of the leaf-cutting ant Acromyrmex octospinosus.

Seipke RF, Crossman L, Drou N, Heavens D, Bibb MJ, Caccamo M, Hutchings MI.

J Bacteriol. 2011 Aug;193(16):4270-1. doi: 10.1128/JB.05275-11. Epub 2011 Jun 17.

19.

A mutualistic microbiome: How do fungus-growing ants select their antibiotic-producing bacteria?

Barke J, Seipke RF, Yu DW, Hutchings MI.

Commun Integr Biol. 2011 Jan;4(1):41-3. doi: 10.4161/cib.4.1.13552.

20.

Dissecting the complete lipoprotein biogenesis pathway in Streptomyces scabies.

Widdick DA, Hicks MG, Thompson BJ, Tschumi A, Chandra G, Sutcliffe IC, Brülle JK, Sander P, Palmer T, Hutchings MI.

Mol Microbiol. 2011 Jun;80(5):1395-412. doi: 10.1111/j.1365-2958.2011.07656.x. Epub 2011 May 2.

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