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Items: 1 to 20 of 42


Nitroxyl (HNO) reduces endothelial and monocyte activation and promotes M2 macrophage polarization.

Andrews KL, Sampson AK, Irvine JC, Shihata WA, Michell DL, Lumsden NG, Lim C, Huet O, Drummond GR, Kemp-Harper BK, Chin-Dusting JP.

Clin Sci (Lond). 2016 Sep 1;130(18):1629-40. doi: 10.1042/CS20160097. Epub 2016 May 26.


Lack of glutathione peroxidase-1 facilitates a pro-inflammatory and activated vascular endothelium.

Sharma A, Yuen D, Huet O, Pickering R, Stefanovic N, Bernatchez P, de Haan JB.

Vascul Pharmacol. 2016 Apr;79:32-42. doi: 10.1016/j.vph.2015.11.001. Epub 2015 Nov 11.


Erythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial.

Nichol A, French C, Little L, Haddad S, Presneill J, Arabi Y, Bailey M, Cooper DJ, Duranteau J, Huet O, Mak A, McArthur C, Pettilä V, Skrifvars M, Vallance S, Varma D, Wills J, Bellomo R; EPO-TBI Investigators; ANZICS Clinical Trials Group.

Lancet. 2015 Dec 19;386(10012):2499-506. doi: 10.1016/S0140-6736(15)00386-4. Epub 2015 Oct 6.


Direct Endothelial Nitric Oxide Synthase Activation Provides Atheroprotection in Diabetes-Accelerated Atherosclerosis.

Sharma A, Sellers S, Stefanovic N, Leung C, Tan SM, Huet O, Granville DJ, Cooper ME, de Haan JB, Bernatchez P.

Diabetes. 2015 Nov;64(11):3937-50. doi: 10.2337/db15-0472. Epub 2015 Jun 26.


Endovascular Versus External Targeted Temperature Management for Patients With Out-of-Hospital Cardiac Arrest: A Randomized, Controlled Study.

Deye N, Cariou A, Girardie P, Pichon N, Megarbane B, Midez P, Tonnelier JM, Boulain T, Outin H, Delahaye A, Cravoisy A, Mercat A, Blanc P, Santré C, Quintard H, Brivet F, Charpentier J, Garrigue D, Francois B, Quenot JP, Vincent F, Gueugniaud PY, Mira JP, Carli P, Vicaut E, Baud FJ; Clinical and Economical Impact of Endovascular Cooling in the Management of Cardiac Arrest (ICEREA) Study Group.

Circulation. 2015 Jul 21;132(3):182-93. doi: 10.1161/CIRCULATIONAHA.114.012805. Epub 2015 Jun 19. Erratum in: Circulation. 2016 Feb 23;133(8):e418.


Stored red blood cell susceptibility to in vitro transfusion-associated stress conditions is higher after longer storage and increased by storage in saline-adenine-glucose-mannitol compared to AS-1.

Mittag D, Sran A, Chan KS, Boland MP, Bandala-Sanchez E, Huet O, Xu W, Sparrow RL.

Transfusion. 2015 Sep;55(9):2197-206. doi: 10.1111/trf.13138. Epub 2015 May 13.


Erythropoietin in traumatic brain injury: study protocol for a randomised controlled trial.

Nichol A, French C, Little L, Presneill J, Cooper DJ, Haddad S, Duranteau J, Huet O, Skrifvars M, Arabi Y, Bellomo R; EPO-TBI Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group.

Trials. 2015 Feb 8;16:39. doi: 10.1186/s13063-014-0528-6.


Norepinephrine Decreases Fluid Requirements and Blood Loss While Preserving Intestinal Villi Microcirculation during Fluid Resuscitation of Uncontrolled Hemorrhagic Shock in Mice.

Harrois A, Baudry N, Huet O, Kato H, Dupic L, Lohez M, Ziol M, Vicaut E, Duranteau J.

Anesthesiology. 2015 May;122(5):1093-102. doi: 10.1097/ALN.0000000000000639.


Compound 21, a selective agonist of angiotensin AT2 receptors, prevents endothelial inflammation and leukocyte adhesion in vitro and in vivo.

Sampson AK, Irvine JC, Shihata WA, Dragoljevic D, Lumsden N, Huet O, Barnes T, Unger T, Steckelings UM, Jennings GL, Widdop RE, Chin-Dusting JP.

Br J Pharmacol. 2016 Feb;173(4):729-40. doi: 10.1111/bph.13063. Epub 2015 Jun 29.


Statistical analysis plan for the Erythropoietin in Traumatic Brain Injury trial: a randomised controlled trial of erythropoietin versus placebo in moderate and severe traumatic brain injury.

Presneill J, Little L, Nichol A, French C, Cooper DJ, Haddad S, Duranteau J, Huet O, Skrifvars M, Arabi Y, Bellomo R; EPO-TBI Investigators; ANZICS Clinical Trials Group.

Trials. 2014 Dec 20;15:501. doi: 10.1186/1745-6215-15-501.


The ethical dimension in published animal research in critical care: the dark side of our moon.

Huet O, de Haan JB.

Crit Care. 2014 Mar 13;18(2):120. doi: 10.1186/cc13766.


Dicarbonyl stress in the absence of hyperglycemia increases endothelial inflammation and atherogenesis similar to that observed in diabetes.

Tikellis C, Pickering RJ, Tsorotes D, Huet O, Cooper ME, Jandeleit-Dahm K, Thomas MC.

Diabetes. 2014 Nov;63(11):3915-25. doi: 10.2337/db13-0932. Epub 2014 May 8.


Microcirculatory alterations in traumatic hemorrhagic shock.

Tachon G, Harrois A, Tanaka S, Kato H, Huet O, Pottecher J, Vicaut E, Duranteau J.

Crit Care Med. 2014 Jun;42(6):1433-41. doi: 10.1097/CCM.0000000000000223.


Septic shock: desperately seeking treatment.

Huet O, Chin-Dusting JP.

Clin Sci (Lond). 2014 Jan 1;126(1):31-9. doi: 10.1042/CS20120668. Review. Erratum in: Clin Sci (Lond). 2014 Mar;126(6):459.


Synergistic deleterious effect of hypoxemia and hypovolemia on microcirculation in intestinal villi*.

Harrois A, Baudry N, Huet O, Kato H, Lohez M, Ziol M, Duranteau J, Vicaut E.

Crit Care Med. 2013 Nov;41(11):e376-84. doi: 10.1097/CCM.0b013e318292388d.


Statement of severe trauma management in France; teachings of the FIRST study.

Tissier C, Bonithon-Kopp C, Freysz M; French Intensive care Recorded in Severe Trauma (FIRST) study group.

Ann Fr Anesth Reanim. 2013 Jul-Aug;32(7-8):465-71. doi: 10.1016/j.annfar.2013.07.003. Epub 2013 Aug 1.


Ensuring animal welfare while meeting scientific aims using a murine pneumonia model of septic shock.

Huet O, Ramsey D, Miljavec S, Jenney A, Aubron C, Aprico A, Stefanovic N, Balkau B, Head GA, de Haan JB, Chin-Dusting JP.

Shock. 2013 Jun;39(6):488-94. doi: 10.1097/SHK.0b013e3182939831.


Interleukin 10 antioxidant effect decreases leukocytes/endothelial interaction induced by tumor necrosis factor α.

Huet O, Laemmel E, Fu Y, Dupic L, Aprico A, Andrews KL, Moore SL, Harrois A, Meikle PL, Vicaut E, Chin-Dusting JP, Duranteau J.

Shock. 2013 Jan;39(1):83-8. doi: 10.1097/SHK.0b013e318278ae36.


Changes in urine composition after trauma facilitate bacterial growth.

Aubron C, Huet O, Ricome S, Borderie D, Pussard E, Leblanc PE, Bouvet O, Vicaut E, Denamur E, Duranteau J.

BMC Infect Dis. 2012 Nov 29;12:330. doi: 10.1186/1471-2334-12-330.


Impact of emergency medical helicopter transport directly to a university hospital trauma center on mortality of severe blunt trauma patients until discharge.

Desmettre T, Yeguiayan JM, Coadou H, Jacquot C, Raux M, Vivien B, Martin C, Bonithon-Kopp C, Freysz M; French Intensive Care Recorded in Severe Trauma.

Crit Care. 2012 Sep 28;16(5):R170. doi: 10.1186/cc11647.

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