Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 88

1.

Biosynthesis of mupirocin by Pseudomonas fluorescens NCIMB 10586 involves parallel pathways.

Gao SS, Hothersall J, Wu J, Murphy AC, Song Z, Stephens ER, Thomas CM, Crump MP, Cox RJ, Simpson TJ, Willis CL.

J Am Chem Soc. 2014 Apr 9;136(14):5501-7. doi: 10.1021/ja501731p. Epub 2014 Mar 27.

PMID:
24625190
[PubMed - in process]
2.

A conserved motif flags acyl carrier proteins for β-branching in polyketide synthesis.

Haines AS, Dong X, Song Z, Farmer R, Williams C, Hothersall J, Płoskoń E, Wattana-amorn P, Stephens ER, Yamada E, Gurney R, Takebayashi Y, Masschelein J, Cox RJ, Lavigne R, Willis CL, Simpson TJ, Crosby J, Winn PJ, Thomas CM, Crump MP.

Nat Chem Biol. 2013 Nov;9(11):685-92. doi: 10.1038/nchembio.1342. Epub 2013 Sep 22.

PMID:
24056399
[PubMed - indexed for MEDLINE]
3.

Prolonged inhibition of 5-HT3 receptors by palonosetron results from surface receptor inhibition rather than inducing receptor internalization.

Hothersall JD, Moffat C, Connolly CN.

Br J Pharmacol. 2013 Jul;169(6):1252-62. doi: 10.1111/bph.12204.

PMID:
23581504
[PubMed - in process]
Free PMC Article
4.

Metabolic fate of the increased yeast amino Acid uptake subsequent to catabolite derepression.

Hothersall JS, Ahmed A.

J Amino Acids. 2013;2013:461901. doi: 10.1155/2013/461901. Epub 2013 Feb 4.

PMID:
23431419
[PubMed]
Free PMC Article
5.

The microsporidian parasites Nosema ceranae and Nosema apis are widespread in honeybee (Apis mellifera) colonies across Scotland.

Bollan KA, Hothersall JD, Moffat C, Durkacz J, Saranzewa N, Wright GA, Raine NE, Highet F, Connolly CN.

Parasitol Res. 2013 Feb;112(2):751-9. doi: 10.1007/s00436-012-3195-0. Epub 2012 Nov 21.

PMID:
23180128
[PubMed - indexed for MEDLINE]
6.

Tamoxifen subcellular localization; observation of cell-specific cytotoxicity enhancement by inhibition of mitochondrial ETC complexes I and III.

Theodossiou TA, Yannakopoulou K, Aggelidou C, Hothersall JS.

Photochem Photobiol. 2012 Jul-Aug;88(4):1016-22. doi: 10.1111/j.1751-1097.2012.01144.x. Epub 2012 Apr 24.

PMID:
22428931
[PubMed - indexed for MEDLINE]
7.

High-affinity fluorescent ligands for the 5-HT(3) receptor.

Simonin J, Vernekar SK, Thompson AJ, Hothersall JD, Connolly CN, Lummis SC, Lochner M.

Bioorg Med Chem Lett. 2012 Jan 15;22(2):1151-5. doi: 10.1016/j.bmcl.2011.11.097. Epub 2011 Dec 1.

PMID:
22189135
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A natural plasmid uniquely encodes two biosynthetic pathways creating a potent anti-MRSA antibiotic.

Fukuda D, Haines AS, Song Z, Murphy AC, Hothersall J, Stephens ER, Gurney R, Cox RJ, Crosby J, Willis CL, Simpson TJ, Thomas CM.

PLoS One. 2011 Mar 31;6(3):e18031. doi: 10.1371/journal.pone.0018031.

PMID:
21483852
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Engineered thiomarinol antibiotics active against MRSA are generated by mutagenesis and mutasynthesis of Pseudoalteromonas SANK73390.

Murphy AC, Fukuda D, Song Z, Hothersall J, Cox RJ, Willis CL, Thomas CM, Simpson TJ.

Angew Chem Int Ed Engl. 2011 Mar 28;50(14):3271-4. doi: 10.1002/anie.201007029. Epub 2011 Mar 4. No abstract available.

PMID:
21381163
[PubMed - indexed for MEDLINE]
10.

The design, synthesis and pharmacological characterization of novel β₂-adrenoceptor antagonists.

Hothersall JD, Black J, Caddick S, Vinter JG, Tinker A, Baker JR.

Br J Pharmacol. 2011 Sep;164(2):317-31. doi: 10.1111/j.1476-5381.2011.01269.x.

PMID:
21323900
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Manipulation of quorum sensing regulation in Pseudomonas fluorescens NCIMB 10586 to increase mupirocin production.

Hothersall J, Murphy AC, Iqbal Z, Campbell G, Stephens ER, Wu J, Cooper H, Atkinson S, Williams P, Crosby J, Willis CL, Cox RJ, Simpson TJ, Thomas CM.

Appl Microbiol Biotechnol. 2011 May;90(3):1017-26. doi: 10.1007/s00253-011-3145-2. Epub 2011 Feb 12.

PMID:
21318358
[PubMed - indexed for MEDLINE]
12.

An efficient asymmetric synthesis of the potent beta-blocker ICI-118,551 allows the determination of enantiomer dependency on biological activity.

Baker JR, Hothersall JD, Fitzmaurice RJ, Tucknott M, Vinter A, Tinker A, Caddick S.

Chem Commun (Camb). 2010 Jun 14;46(22):3953-4. doi: 10.1039/c0cc00142b. Epub 2010 Apr 30.

PMID:
20431838
[PubMed - indexed for MEDLINE]
13.

Hydrogen sulfide improves neutrophil migration and survival in sepsis via K+ATP channel activation.

Spiller F, Orrico MI, Nascimento DC, Czaikoski PG, Souto FO, Alves-Filho JC, Freitas A, Carlos D, Montenegro MF, Neto AF, Ferreira SH, Rossi MA, Hothersall JS, Assreuy J, Cunha FQ.

Am J Respir Crit Care Med. 2010 Aug 1;182(3):360-8. doi: 10.1164/rccm.200907-1145OC. Epub 2010 Mar 25.

PMID:
20339148
[PubMed - indexed for MEDLINE]
14.

Resistance to and synthesis of the antibiotic mupirocin.

Thomas CM, Hothersall J, Willis CL, Simpson TJ.

Nat Rev Microbiol. 2010 Apr;8(4):281-9. doi: 10.1038/nrmicro2278. Epub 2010 Mar 1. Review.

PMID:
20190824
[PubMed - indexed for MEDLINE]
15.

Morphine peripheral analgesia depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathway.

Cunha TM, Roman-Campos D, Lotufo CM, Duarte HL, Souza GR, Verri WA Jr, Funez MI, Dias QM, Schivo IR, Domingues AC, Sachs D, Chiavegatto S, Teixeira MM, Hothersall JS, Cruz JS, Cunha FQ, Ferreira SH.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4442-7. doi: 10.1073/pnas.0914733107. Epub 2010 Feb 10.

PMID:
20147620
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Phosphopantetheinylation and specificity of acyl carrier proteins in the mupirocin biosynthetic cluster.

Shields JA, Rahman AS, Arthur CJ, Crosby J, Hothersall J, Simpson TJ, Thomas CM.

Chembiochem. 2010 Jan 25;11(2):248-55. doi: 10.1002/cbic.200900565.

PMID:
20013982
[PubMed - indexed for MEDLINE]
17.

Hypericin hydroquinone: potential as a red-far red photosensitizer?

Theodossiou TA, Tsiourvas D, Hothersall JS.

Photochem Photobiol. 2010 Jan-Feb;86(1):18-22. doi: 10.1111/j.1751-1097.2009.00668.x. Epub 2009 Dec 7.

PMID:
20003155
[PubMed - indexed for MEDLINE]
18.

The multifaceted photocytotoxic profile of hypericin.

Theodossiou TA, Hothersall JS, De Witte PA, Pantos A, Agostinis P.

Mol Pharm. 2009 Nov-Dec;6(6):1775-89. doi: 10.1021/mp900166q. Review.

PMID:
19739671
[PubMed - indexed for MEDLINE]
19.

Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens.

Silby MW, Cerdeño-Tárraga AM, Vernikos GS, Giddens SR, Jackson RW, Preston GM, Zhang XX, Moon CD, Gehrig SM, Godfrey SA, Knight CG, Malone JG, Robinson Z, Spiers AJ, Harris S, Challis GL, Yaxley AM, Harris D, Seeger K, Murphy L, Rutter S, Squares R, Quail MA, Saunders E, Mavromatis K, Brettin TS, Bentley SD, Hothersall J, Stephens E, Thomas CM, Parkhill J, Levy SB, Rainey PB, Thomson NR.

Genome Biol. 2009;10(5):R51. doi: 10.1186/gb-2009-10-5-r51. Epub 2009 May 11.

PMID:
19432983
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont.

Lopanik NB, Shields JA, Buchholz TJ, Rath CM, Hothersall J, Haygood MG, Håkansson K, Thomas CM, Sherman DH.

Chem Biol. 2008 Nov 24;15(11):1175-86. doi: 10.1016/j.chembiol.2008.09.013.

PMID:
19022178
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Loading ...
Write to the Help Desk