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Results: 1 to 20 of 289

1.

Heme oxygenase-1 protects against Alzheimer's amyloid-β1-42-induced toxicity via carbon monoxide production.

Hettiarachchi N, Dallas M, Al-Owais M, Griffiths H, Hooper N, Scragg J, Boyle J, Peers C.

Cell Death Dis. 2014 Dec 11;5:e1569. doi: 10.1038/cddis.2014.529.

PMID:
25501830
[PubMed - in process]
2.

Lipid rafts: linking prion protein to zinc transport and amyloid-β toxicity in Alzheimer's disease.

Watt NT, Griffiths HH, Hooper NM.

Front Cell Dev Biol. 2014 Aug 20;2:41. doi: 10.3389/fcell.2014.00041. eCollection 2014.

PMID:
25364748
[PubMed]
Free PMC Article
3.

Exome sequencing identifies 2 novel presenilin 1 mutations (p.L166V and p.S230R) in British early-onset Alzheimer's disease.

Sassi C, Guerreiro R, Gibbs R, Ding J, Lupton MK, Troakes C, Lunnon K, Al-Sarraj S, Brown KS, Medway C, Lord J, Turton J, Mann D, Snowden J, Neary D, Harris J, Bras J; ARUK Consortium, Morgan K, Powell JF, Singleton A, Hardy J.

Neurobiol Aging. 2014 Oct;35(10):2422.e13-6. doi: 10.1016/j.neurobiolaging.2014.04.026. Epub 2014 May 2.

PMID:
24880964
[PubMed - in process]
Free PMC Article
4.

Angiotensin-converting enzyme 2 is subject to post-transcriptional regulation by miR-421.

Lambert DW, Lambert LA, Clarke NE, Hooper NM, Porter KE, Turner AJ.

Clin Sci (Lond). 2014 Aug;127(4):243-9. doi: 10.1042/CS20130420.

PMID:
24564768
[PubMed - indexed for MEDLINE]
5.

A label-free electrical impedimetric biosensor for the specific detection of Alzheimer's amyloid-beta oligomers.

Rushworth JV, Ahmed A, Griffiths HH, Pollock NM, Hooper NM, Millner PA.

Biosens Bioelectron. 2014 Jun 15;56:83-90. doi: 10.1016/j.bios.2013.12.036. Epub 2013 Dec 24.

PMID:
24480125
[PubMed - indexed for MEDLINE]
6.

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease.

Cruchaga C, Karch CM, Jin SC, Benitez BA, Cai Y, Guerreiro R, Harari O, Norton J, Budde J, Bertelsen S, Jeng AT, Cooper B, Skorupa T, Carrell D, Levitch D, Hsu S, Choi J, Ryten M; UK Brain Expression Consortium, Hardy J, Ryten M, Trabzuni D, Weale ME, Ramasamy A, Smith C, Sassi C, Bras J, Gibbs JR, Hernandez DG, Lupton MK, Powell J, Forabosco P, Ridge PG, Corcoran CD, Tschanz JT, Norton MC, Munger RG, Schmutz C, Leary M, Demirci FY, Bamne MN, Wang X, Lopez OL, Ganguli M, Medway C, Turton J, Lord J, Braae A, Barber I, Brown K; Alzheimer’s Research UK Consortium, Passmore P, Craig D, Johnston J, McGuinness B, Todd S, Heun R, Kölsch H, Kehoe PG, Hooper NM, Vardy ER, Mann DM, Pickering-Brown S, Brown K, Kalsheker N, Lowe J, Morgan K, David Smith A, Wilcock G, Warden D, Holmes C, Pastor P, Lorenzo-Betancor O, Brkanac Z, Scott E, Topol E, Morgan K, Rogaeva E, Singleton AB, Hardy J, Kamboh MI, St George-Hyslop P, Cairns N, Morris JC, Kauwe JS, Goate AM.

Nature. 2014 Jan 23;505(7484):550-4. doi: 10.1038/nature12825. Epub 2013 Dec 11.

PMID:
24336208
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

BIN1 is decreased in sporadic but not familial Alzheimer's disease or in aging.

Glennon EB, Whitehouse IJ, Miners JS, Kehoe PG, Love S, Kellett KA, Hooper NM.

PLoS One. 2013 Oct 21;8(10):e78806. doi: 10.1371/journal.pone.0078806. eCollection 2013.

PMID:
24205320
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.

Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MW, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuiness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Deniz Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F; European Alzheimer's Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer's Disease; Alzheimer's Disease Genetic Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology, Moebus S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannefelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltuenen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel P.

Nat Genet. 2013 Dec;45(12):1452-8. doi: 10.1038/ng.2802. Epub 2013 Oct 27.

PMID:
24162737
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Should a Patients BMI Status be Used to Restrict Access to Total Hip and Knee Arthroplasty? Functional Outcomes of Arthroplasty Relative to BMI - Single Centre Retrospective Review.

Lash H, Hooper G, Hooper N, Frampton C.

Open Orthop J. 2013 Oct 4;7:594-9. doi: 10.2174/1874325001307010594. eCollection 2013.

PMID:
24155808
[PubMed]
Free PMC Article
10.

The outcome of bone substitute wedges in medial opening high tibial osteotomy.

Hooper NM, Schouten R, Hooper GJ.

Open Orthop J. 2013 Sep 6;7:373-7. doi: 10.2174/1874325001307010373. eCollection 2013.

PMID:
24082978
[PubMed]
Free PMC Article
11.

The effects of repeated thought suppression attempts on thought occurrence.

Hooper N, McHugh L.

Am J Psychol. 2013 Fall;126(3):315-22.

PMID:
24027945
[PubMed - indexed for MEDLINE]
12.

Neuronal zinc regulation and the prion protein.

Watt NT, Griffiths HH, Hooper NM.

Prion. 2013 May-Jun;7(3):203-8. doi: 10.4161/pri.24503. Review.

PMID:
23764834
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Prion protein is decreased in Alzheimer's brain and inversely correlates with BACE1 activity, amyloid-β levels and Braak stage.

Whitehouse IJ, Miners JS, Glennon EB, Kehoe PG, Love S, Kellett KA, Hooper NM.

PLoS One. 2013;8(4):e59554. doi: 10.1371/journal.pone.0059554. Epub 2013 Apr 5.

PMID:
23577068
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Prion protein-mediated toxicity of amyloid-β oligomers requires lipid rafts and the transmembrane LRP1.

Rushworth JV, Griffiths HH, Watt NT, Hooper NM.

J Biol Chem. 2013 Mar 29;288(13):8935-51. doi: 10.1074/jbc.M112.400358. Epub 2013 Feb 5.

PMID:
23386614
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Discovery of biphenylacetamide-derived inhibitors of BACE1 using de novo structure-based molecular design.

Mok NY, Chadwick J, Kellett KA, Casas-Arce E, Hooper NM, Johnson AP, Fishwick CW.

J Med Chem. 2013 Mar 14;56(5):1843-52. doi: 10.1021/jm301127x. Epub 2013 Feb 22.

PMID:
23374014
[PubMed - indexed for MEDLINE]
16.

Prion protein facilitates uptake of zinc into neuronal cells.

Watt NT, Taylor DR, Kerrigan TL, Griffiths HH, Rushworth JV, Whitehouse IJ, Hooper NM.

Nat Commun. 2012;3:1134. doi: 10.1038/ncomms2135.

PMID:
23072804
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Substitution of rifapentine for rifampin during intensive phase treatment of pulmonary tuberculosis: study 29 of the tuberculosis trials consortium.

Dorman SE, Goldberg S, Stout JE, Muzanyi G, Johnson JL, Weiner M, Bozeman L, Heilig CM, Feng PJ, Moro R, Narita M, Nahid P, Ray S, Bates E, Haile B, Nuermberger EL, Vernon A, Schluger NW; Tuberculosis Trials Consortium.

J Infect Dis. 2012 Oct 1;206(7):1030-40. Epub 2012 Jul 30.

PMID:
22850121
[PubMed - indexed for MEDLINE]
Free Article
18.

The relationship between the American Society Of Anesthesiologists physical rating and outcome following total hip and knee arthroplasty: an analysis of theNew Zealand Joint Registry.

Hooper GJ, Rothwell AG, Hooper NM, Frampton C.

J Bone Joint Surg Am. 2012 Jun 20;94(12):1065-70. doi: 10.2106/JBJS.J.01681.

PMID:
22717825
[PubMed - indexed for MEDLINE]
19.

Regulation of amyloid-β production by the prion protein.

Griffiths HH, Whitehouse IJ, Hooper NM.

Prion. 2012 Jul 1;6(3):217-22. doi: 10.4161/pri.18988. Epub 2012 Jul 1.

PMID:
22449984
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Cellular prion protein expression is not regulated by the Alzheimer's amyloid precursor protein intracellular domain.

Lewis V, Whitehouse IJ, Baybutt H, Manson JC, Collins SJ, Hooper NM.

PLoS One. 2012;7(2):e31754. doi: 10.1371/journal.pone.0031754. Epub 2012 Feb 21.

PMID:
22363722
[PubMed - indexed for MEDLINE]
Free PMC Article

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