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Results: 1 to 20 of 116


Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton.

Tijchon E, van Ingen Schenau D, van Opzeeland F, Tirone F, Hoogerbrugge PM, Van Leeuwen FN, Scheijen B.

PLoS One. 2015 Jul 28;10(7):e0131481. doi: 10.1371/journal.pone.0131481. eCollection 2015.


Independent development of lymphoid and histiocytic malignancies from a shared early precursor.

Waanders E, Hebeda KM, Kamping EJ, Groenen PJ, Simons A, Hoischen A, Jongmans MC, Hoogerbrugge PM, van Leeuwen FN, Kuiper RP, Te Loo DM.

Leukemia. 2015 Jul 23. doi: 10.1038/leu.2015.193. [Epub ahead of print] No abstract available.


Illness cognitions and family adjustment: psychometric properties of the Illness Cognition Questionnaire for parents of a child with cancer.

Sint Nicolaas SM, Schepers SA, van den Bergh EM, Evers AW, Hoogerbrugge PM, Grootenhuis MA, Verhaak CM.

Support Care Cancer. 2015 Jun 25. [Epub ahead of print]


Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial.

Bielack SS, Smeland S, Whelan JS, Marina N, Jovic G, Hook JM, Krailo MD, Gebhardt M, Pápai Z, Meyer J, Nadel H, Randall RL, Deffenbaugh C, Nagarajan R, Brennan B, Letson GD, Teot LA, Goorin A, Baumhoer D, Kager L, Werner M, Lau CC, Sundby Hall K, Gelderblom H, Meyers P, Gorlick R, Windhager R, Helmke K, Eriksson M, Hoogerbrugge PM, Schomberg P, Tunn PU, Kühne T, Jürgens H, van den Berg H, Böhling T, Picton S, Renard M, Reichardt P, Gerss J, Butterfass-Bahloul T, Morris C, Hogendoorn PC, Seddon B, Calaminus G, Michelagnoli M, Dhooge C, Sydes MR, Bernstein M; EURAMOS-1 investigators.

J Clin Oncol. 2015 Jul 10;33(20):2279-87. doi: 10.1200/JCO.2014.60.0734. Epub 2015 Jun 1.


A First Step toward Personalized Medicine in Osteosarcoma: Pharmacogenetics as Predictive Marker of Outcome after Chemotherapy-Based Treatment.

Hagleitner MM, Coenen MJ, Gelderblom H, Makkinje RR, Vos HI, de Bont ES, van der Graaf WT, Schreuder HW, Flucke U, van Leeuwen FN, Hoogerbrugge PM, Guchelaar HJ, Te Loo DM.

Clin Cancer Res. 2015 Mar 31. [Epub ahead of print]


TRPM7 maintains progenitor-like features of neuroblastoma cells: implications for metastasis formation.

Middelbeek J, Visser D, Henneman L, Kamermans A, Kuipers AJ, Hoogerbrugge PM, Jalink K, van Leeuwen FN.

Oncotarget. 2015 Apr 20;6(11):8760-76.


Intra-adrenal murine TH-MYCN neuroblastoma tumors grow more aggressive and exhibit a distinct tumor microenvironment relative to their subcutaneous equivalents.

Kroesen M, Brok IC, Reijnen D, van Hout-Kuijer MA, Zeelenberg IS, Den Brok MH, Hoogerbrugge PM, Adema GJ.

Cancer Immunol Immunother. 2015 May;64(5):563-72. doi: 10.1007/s00262-015-1663-y. Epub 2015 Feb 17.


Influence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant heterogeneity between cohorts.

Hagleitner MM, Coenen MJ, Patino-Garcia A, de Bont ES, Gonzalez-Neira A, Vos HI, van Leeuwen FN, Gelderblom H, Hoogerbrugge PM, Guchelaar HJ, Te Loo MW.

PLoS One. 2014 Dec 31;9(12):e115869. doi: 10.1371/journal.pone.0115869. eCollection 2014.


A germ line mutation in cathepsin B points toward a role in asparaginase pharmacokinetics.

van der Meer LT, Waanders E, Levers M, Venselaar H, Roeleveld D, Boos J, Lanvers C, Brüggemann RJ, Kuiper RP, Hoogerbrugge PM, van Leeuwen FN, te Loo DM.

Blood. 2014 Nov 6;124(19):3027-9. doi: 10.1182/blood-2014-06-582627. No abstract available.


Outcome of central nervous system relapses in childhood acute lymphoblastic leukaemia--prospective open cohort analyses of the ALLR3 trial.

Masurekar AN, Parker CA, Shanyinde M, Moorman AV, Hancock JP, Sutton R, Ancliff PJ, Morgan M, Goulden NJ, Fraser C, Hoogerbrugge PM, Revesz T, Darbyshire PJ, Krishnan S, Love SB, Saha V.

PLoS One. 2014 Oct 3;9(10):e108107. doi: 10.1371/journal.pone.0108107. eCollection 2014.


HDAC inhibitors and immunotherapy; a double edged sword?

Kroesen M, Gielen P, Brok IC, Armandari I, Hoogerbrugge PM, Adema GJ.

Oncotarget. 2014 Aug 30;5(16):6558-72. Review.


The optimal use of PEG-asparaginase in relapsed ALL--lessons from the ALLR3 Clinical Trial.

Masurekar A, Fong C, Hussein A, Revesz T, Hoogerbrugge PM, Love S, Ciria C, Parker C, Krishnan S, Saha V.

Blood Cancer J. 2014 Apr 25;4:e203. doi: 10.1038/bcj.2014.26. No abstract available.


Self-perception and quality of life in adolescents during treatment for a primary malignant bone tumour.

van Riel CA, Meijer-van den Bergh EE, Kemps HL, Feuth T, Schreuder HW, Hoogerbrugge PM, De Groot IJ, Mavinkurve-Groothuis AM.

Eur J Oncol Nurs. 2014 Jun;18(3):267-72. doi: 10.1016/j.ejon.2014.01.005. Epub 2014 Mar 18.


Patient reported outcomes in pediatric oncology practice: suggestions for future usage by parents and pediatric oncologists.

Schepers SA, Engelen VE, Haverman L, Caron HN, Hoogerbrugge PM, Kaspers GJ, Egeler RM, Grootenhuis MA.

Pediatr Blood Cancer. 2014 Sep;61(9):1707-10. doi: 10.1002/pbc.25034. Epub 2014 Mar 20.


A transplantable TH-MYCN transgenic tumor model in C57Bl/6 mice for preclinical immunological studies in neuroblastoma.

Kroesen M, Nierkens S, Ansems M, Wassink M, Orentas RJ, Boon L, den Brok MH, Hoogerbrugge PM, Adema GJ.

Int J Cancer. 2014 Mar 15;134(6):1335-45. doi: 10.1002/ijc.28463. Epub 2013 Sep 14.


Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL.

van der Veer A, Waanders E, Pieters R, Willemse ME, Van Reijmersdal SV, Russell LJ, Harrison CJ, Evans WE, van der Velden VH, Hoogerbrugge PM, Van Leeuwen F, Escherich G, Horstmann MA, Mohammadi Khankahdani L, Rizopoulos D, De Groot-Kruseman HA, Sonneveld E, Kuiper RP, Den Boer ML.

Blood. 2013 Oct 10;122(15):2622-9. doi: 10.1182/blood-2012-10-462358. Epub 2013 Aug 23.


Adequate endocrine and cardiovascular response to social stress in survivors of childhood acute lymphoblastic leukemia.

Gordijn MS, Gemke RJ, Bierings MB, Hoogerbrugge PM, Tersteeg-Kamperman MD, Heijnen CJ, Rotteveel J, Kaspers GJ.

Psychoneuroendocrinology. 2013 Dec;38(12):3145-9. doi: 10.1016/j.psyneuen.2013.07.013. Epub 2013 Aug 5.


The role of the MTHFR 677C>T polymorphism in methotrexate-induced liver toxicity: a meta-analysis in patients with cancer.

Hagleitner MM, Coenen MJ, Aplenc R, Patiño-Garcia A, Chiusolo P, Gemmati D, De Mattei M, Ongaro A, Krajinovic M, Hoogerbrugge PM, Vermeulen SH, te Loo DM.

Pharmacogenomics J. 2014 Apr;14(2):115-9. doi: 10.1038/tpj.2013.19. Epub 2013 May 7.


High-risk childhood acute lymphoblastic leukemia in first remission treated with novel intensive chemotherapy and allogeneic transplantation.

Marshall GM, Dalla Pozza L, Sutton R, Ng A, de Groot-Kruseman HA, van der Velden VH, Venn NC, van den Berg H, de Bont ES, Maarten Egeler R, Hoogerbrugge PM, Kaspers GJ, Bierings MB, van der Schoot E, van Dongen J, Law T, Cross S, Mueller H, de Haas V, Haber M, Révész T, Alvaro F, Suppiah R, Norris MD, Pieters R.

Leukemia. 2013 Jul;27(7):1497-503. doi: 10.1038/leu.2013.44. Epub 2013 Feb 14.


Absolute lymphocyte count predicts the response to new influenza virus H1N1 vaccination in pediatric cancer patients.

Mavinkurve-Groothuis AM, van der Flier M, Stelma F, van Leer-Buter C, Preijers FW, Hoogerbrugge PM.

Clin Vaccine Immunol. 2013 Jan;20(1):118-21. doi: 10.1128/CVI.00585-12. Epub 2012 Nov 21.

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