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Results: 1 to 20 of 59

1.

Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events.

Wong VK, Baker S, Pickard DJ, Parkhill J, Page AJ, Feasey NA, Kingsley RA, Thomson NR, Keane JA, Weill FX, Edwards DJ, Hawkey J, Harris SR, Mather AE, Cain AK, Hadfield J, Hart PJ, Thieu NT, Klemm EJ, Glinos DA, Breiman RF, Watson CH, Kariuki S, Gordon MA, Heyderman RS, Okoro C, Jacobs J, Lunguya O, Edmunds WJ, Msefula C, Chabalgoity JA, Kama M, Jenkins K, Dutta S, Marks F, Campos J, Thompson C, Obaro S, MacLennan CA, Dolecek C, Keddy KH, Smith AM, Parry CM, Karkey A, Mulholland EK, Campbell JI, Dongol S, Basnyat B, Dufour M, Bandaranayake D, Naseri TT, Singh SP, Hatta M, Newton P, Onsare RS, Isaia L, Dance D, Davong V, Thwaites G, Wijedoru L, Crump JA, De Pinna E, Nair S, Nilles EJ, Thanh DP, Turner P, Soeng S, Valcanis M, Powling J, Dimovski K, Hogg G, Farrar J, Holt KE, Dougan G.

Nat Genet. 2015 May 11. doi: 10.1038/ng.3281. [Epub ahead of print]

PMID:
25961941
2.

A platform for leveraging next generation sequencing for routine microbiology and public health use.

Rusu LI, Wyres KL, Reumann M, Queiroz C, Bojovschi A, Conway T, Garg S, Edwards DJ, Hogg G, Holt KE.

Health Inf Sci Syst. 2015 Feb 24;3(Suppl 1 HISA Big Data in Biomedicine and Healthcare 2013 Con):S7. doi: 10.1186/2047-2501-3-S1-S7. eCollection 2015.

3.

The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development.

Teo SM, Mok D, Pham K, Kusel M, Serralha M, Troy N, Holt BJ, Hales BJ, Walker ML, Hollams E, Bochkov YA, Grindle K, Johnston SL, Gern JE, Sly PD, Holt PG, Holt KE, Inouye M.

Cell Host Microbe. 2015 May 13;17(5):704-15. doi: 10.1016/j.chom.2015.03.008. Epub 2015 Apr 9.

PMID:
25865368
4.

Extensive Capsule Locus Variation and Large-Scale Genomic Recombination within the Klebsiella pneumoniae Clonal Group 258.

Wyres KL, Gorrie C, Edwards DJ, Wertheim HF, Hsu LY, Van Kinh N, Zadoks R, Baker S, Holt KE.

Genome Biol Evol. 2015 Apr 10;7(5):1267-79. doi: 10.1093/gbe/evv062.

5.

Multidrug-resistant Salmonella enterica serotype Typhi, Gulf of Guinea Region, Africa.

Baltazar M, Ngandjio A, Holt KE, Lepillet E, Pardos de la Gandara M, Collard JM, Bercion R, Nzouankeu A, Le Hello S, Dougan G, Fonkoua MC, Weill FX.

Emerg Infect Dis. 2015 Apr;21(4):655-9. doi: 10.3201/eid2104.141355.

6.

Genome Sequence of Acinetobacter baumannii Strain A1, an Early Example of Antibiotic-Resistant Global Clone 1.

Holt KE, Hamidian M, Kenyon JJ, Wynn MT, Hawkey J, Pickard D, Hall RM.

Genome Announc. 2015 Mar 12;3(2). pii: e00032-15. doi: 10.1128/genomeA.00032-15.

7.

Convergent adaptation in the dominant global hospital clone ST239 of methicillin-resistant Staphylococcus aureus.

Baines SL, Holt KE, Schultz MB, Seemann T, Howden BO, Jensen SO, van Hal SJ, Coombs GW, Firth N, Powell DR, Stinear TP, Howden BP.

MBio. 2015 Mar 3;6(2):e00080. doi: 10.1128/mBio.00080-15.

8.

A type 2 A/C2 plasmid carrying the aacC4 apramycin resistance gene and the erm(42) erythromycin resistance gene recovered from two Salmonella enterica serovars.

Harmer CJ, Holt KE, Hall RM.

J Antimicrob Chemother. 2015 Apr;70(4):1021-5. doi: 10.1093/jac/dku489. Epub 2014 Dec 2.

PMID:
25468903
9.

Carbapenem and amikacin resistance on a large conjugative Acinetobacter baumannii plasmid.

Nigro SJ, Holt KE, Pickard D, Hall RM.

J Antimicrob Chemother. 2015 Apr;70(4):1259-61. doi: 10.1093/jac/dku486. Epub 2014 Nov 27. No abstract available.

10.

SRST2: Rapid genomic surveillance for public health and hospital microbiology labs.

Inouye M, Dashnow H, Raven LA, Schultz MB, Pope BJ, Tomita T, Zobel J, Holt KE.

Genome Med. 2014 Nov 20;6(11):90. doi: 10.1186/s13073-014-0090-6. eCollection 2014.

11.

The complete sequence of Salmonella genomic island SGI2.

Hamidian M, Holt KE, Hall RM.

J Antimicrob Chemother. 2015 Feb;70(2):617-9. doi: 10.1093/jac/dku407. Epub 2014 Oct 14. No abstract available.

PMID:
25315365
12.

Elucidation of pathways driving asthma pathogenesis: development of a systems-level analytic strategy.

Walker ML, Holt KE, Anderson GP, Teo SM, Sly PD, Holt PG, Inouye M.

Front Immunol. 2014 Sep 23;5:447. doi: 10.3389/fimmu.2014.00447. eCollection 2014. Review.

13.

The complete sequence of Salmonella genomic island SGI1-K.

Hamidian M, Holt KE, Hall RM.

J Antimicrob Chemother. 2015 Jan;70(1):305-6. doi: 10.1093/jac/dku331. Epub 2014 Sep 4. No abstract available.

PMID:
25193084
14.

Analysis of Salmonella enterica serovar Typhimurium variable-number tandem-repeat data for public health investigation based on measured mutation rates and whole-genome sequence comparisons.

Dimovski K, Cao H, Wijburg OL, Strugnell RA, Mantena RK, Whipp M, Hogg G, Holt KE.

J Bacteriol. 2014 Aug 15;196(16):3036-44. doi: 10.1128/JB.01820-14. Epub 2014 Jun 23.

15.

A conjugative plasmid carrying the carbapenem resistance gene blaOXA-23 in AbaR4 in an extensively resistant GC1 Acinetobacter baumannii isolate.

Hamidian M, Kenyon JJ, Holt KE, Pickard D, Hall RM.

J Antimicrob Chemother. 2014 Oct;69(10):2625-8. doi: 10.1093/jac/dku188. Epub 2014 Jun 6.

PMID:
24907141
16.

Insertions in the OCL1 locus of Acinetobacter baumannii lead to shortened lipooligosaccharides.

Kenyon JJ, Holt KE, Pickard D, Dougan G, Hall RM.

Res Microbiol. 2014 Jul-Aug;165(6):472-5. doi: 10.1016/j.resmic.2014.05.034. Epub 2014 May 23.

17.

An outpatient, ambulant-design, controlled human infection model using escalating doses of Salmonella Typhi challenge delivered in sodium bicarbonate solution.

Waddington CS, Darton TC, Jones C, Haworth K, Peters A, John T, Thompson BA, Kerridge SA, Kingsley RA, Zhou L, Holt KE, Yu LM, Lockhart S, Farrar JJ, Sztein MB, Dougan G, Angus B, Levine MM, Pollard AJ.

Clin Infect Dis. 2014 May;58(9):1230-40. doi: 10.1093/cid/ciu078. Epub 2014 Feb 10.

18.

Adaptive change inferred from genomic population analysis of the ST93 epidemic clone of community-associated methicillin-resistant Staphylococcus aureus.

Stinear TP, Holt KE, Chua K, Stepnell J, Tuck KL, Coombs G, Harrison PF, Seemann T, Howden BP.

Genome Biol Evol. 2014 Feb;6(2):366-78. doi: 10.1093/gbe/evu022.

19.

Characterization of the yehUT two-component regulatory system of Salmonella enterica Serovar Typhi and Typhimurium.

Wong VK, Pickard DJ, Barquist L, Sivaraman K, Page AJ, Hart PJ, Arends MJ, Holt KE, Kane L, Mottram LF, Ellison L, Bautista R, McGee CJ, Kay SJ, Wileman TM, Kenney LJ, MacLennan CA, Kingsley RA, Dougan G.

PLoS One. 2013 Dec 30;8(12):e84567. doi: 10.1371/journal.pone.0084567. eCollection 2013.

20.

Evidence of microevolution of Salmonella Typhimurium during a series of egg-associated outbreaks linked to a single chicken farm.

Hawkey J, Edwards DJ, Dimovski K, Hiley L, Billman-Jacobe H, Hogg G, Holt KE.

BMC Genomics. 2013 Nov 19;14:800. doi: 10.1186/1471-2164-14-800.

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