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Results: 1 to 20 of 768

1.

Common genetic variants influence human subcortical brain structures.

Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivières S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, Aribisala BS, Armstrong NJ, Bernard M, Bohlken MM, Boks MP, Bralten J, Brown AA, Mallar Chakravarty M, Chen Q, Ching CR, Cuellar-Partida G, den Braber A, Giddaluru S, Goldman AL, Grimm O, Guadalupe T, Hass J, Woldehawariat G, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kim S, Klein M, Kraemer B, Lee PH, Olde Loohuis LM, Luciano M, Macare C, Mather KA, Mattheisen M, Milaneschi Y, Nho K, Papmeyer M, Ramasamy A, Risacher SL, Roiz-Santiañez R, Rose EJ, Salami A, Sämann PG, Schmaal L, Schork AJ, Shin J, Strike LT, Teumer A, van Donkelaar MM, van Eijk KR, Walters RK, Westlye LT, Whelan CD, Winkler AM, Zwiers MP, Alhusaini S, Athanasiu L, Ehrlich S, Hakobjan MM, Hartberg CB, Haukvik UK, Heister AJ, Hoehn D, Kasperaviciute D, Liewald DC, Lopez LM, Makkinje RR, Matarin M, Naber MA, Reese McKay D, Needham M, Nugent AC, Pütz B, Royle NA, Shen L, Sprooten E, Trabzuni D, van der Marel SS, van Hulzen KJ, Walton E, Wolf C, Almasy L, Ames D, Arepalli S, Assareh AA, Bastin ME, Brodaty H, Bulayeva KB, Carless MA, Cichon S, Corvin A, Curran JE, Czisch M, de Zubicaray GI, Dillman A, Duggirala R, Dyer TD, Erk S, Fedko IO, Ferrucci L, Foroud TM, Fox PT, Fukunaga M, Raphael Gibbs J, Göring HH, Green RC, Guelfi S, Hansell NK, Hartman CA, Hegenscheid K, Heinz A, Hernandez DG, Heslenfeld DJ, Hoekstra PJ, Holsboer F, Homuth G, Hottenga JJ, Ikeda M, Jack CR Jr, Jenkinson M, Johnson R, Kanai R, Keil M, Kent JW Jr, Kochunov P, Kwok JB, Lawrie SM, Liu X, Longo DL, McMahon KL, Meisenzahl E, Melle I, Mohnke S, Montgomery GW, Mostert JC, Mühleisen TW, Nalls MA, Nichols TE, Nilsson LG, Nöthen MM, Ohi K, Olvera RL, Perez-Iglesias R, Bruce Pike G, Potkin SG, Reinvang I, Reppermund S, Rietschel M, Romanczuk-Seiferth N, Rosen GD, Rujescu D, Schnell K, Schofield PR, Smith C, Steen VM, Sussmann JE, Thalamuthu A, Toga AW, Traynor BJ, Troncoso J, Turner JA, Valdés Hernández MC, van 't Ent D, van der Brug M, van der Wee NJ, van Tol MJ, Veltman DJ, Wassink TH, Westman E, Zielke RH, Zonderman AB, Ashbrook DG, Hager R, Lu L, McMahon FJ, Morris DW, Williams RW, Brunner HG, Buckner RL, Buitelaar JK, Cahn W, Calhoun VD, Cavalleri GL, Crespo-Facorro B, Dale AM, Davies GE, Delanty N, Depondt C, Djurovic S, Drevets WC, Espeseth T, Gollub RL, Ho BC, Hoffmann W, Hosten N, Kahn RS, Le Hellard S, Meyer-Lindenberg A, Müller-Myhsok B, Nauck M, Nyberg L, Pandolfo M, Penninx BW, Roffman JL, Sisodiya SM, Smoller JW, van Bokhoven H, van Haren NE, Völzke H, Walter H, Weiner MW, Wen W, White T, Agartz I, Andreassen OA, Blangero J, Boomsma DI, Brouwer RM, Cannon DM, Cookson MR, de Geus EJ, Deary IJ, Donohoe G, Fernández G, Fisher SE, Francks C, Glahn DC, Grabe HJ, Gruber O, Hardy J, Hashimoto R, Hulshoff Pol HE, Jönsson EG, Kloszewska I, Lovestone S, Mattay VS, Mecocci P, McDonald C, McIntosh AM, Ophoff RA, Paus T, Pausova Z, Ryten M, Sachdev PS, Saykin AJ, Simmons A, Singleton A, Soininen H, Wardlaw JM, Weale ME, Weinberger DR, Adams HH, Launer LJ, Seiler S, Schmidt R, Chauhan G, Satizabal CL, Becker JT, Yanek L, van der Lee SJ, Ebling M, Fischl B, Longstreth WT Jr, Greve D, Schmidt H, Nyquist P, Vinke LN, van Duijn CM, Xue L, Mazoyer B, Bis JC, Gudnason V, Seshadri S, Arfan Ikram M; The Alzheimer’s Disease Neuroimaging Initiative; The CHARGE Consortium; EPIGEN; IMAGEN; SYS, Martin NG, Wright MJ, Schumann G, Franke B, Thompson PM, Medland SE.

Nature. 2015 Jan 21. doi: 10.1038/nature14101. [Epub ahead of print]

PMID:
25607358
[PubMed - as supplied by publisher]
2.

Cell type-specific modifications of corticotropin-releasing factor (CRF) and its type 1 receptor (CRF1) on startle behavior and sensorimotor gating.

Flandreau E, Risbrough V, Lu A, Ableitner M, Geyer MA, Holsboer F, Deussing JM.

Psychoneuroendocrinology. 2014 Dec 11;53C:16-28. doi: 10.1016/j.psyneuen.2014.12.005. [Epub ahead of print]

PMID:
25575243
[PubMed - as supplied by publisher]
3.

FKBP5 genotype-dependent DNA methylation and mRNA regulation after psychosocial stress in remitted depression and healthy controls.

Höehne N, Poidinger M, Merz F, Pfister H, Brückl T, Zimmermann P, Uhr M, Holsboer F, Ising M.

Int J Neuropsychopharmacol. 2014 Dec 13. pii: pyu087. [Epub ahead of print]

PMID:
25522420
[PubMed - as supplied by publisher]
4.

RSUME inhibits VHL and regulates its tumor suppressor function.

Gerez J, Tedesco L, Bonfiglio JJ, Fuertes M, Barontini M, Silberstein S, Wu Y, Renner U, Páez-Pereda M, Holsboer F, Stalla GK, Arzt E.

Oncogene. 2014 Dec 15;0. doi: 10.1038/onc.2014.407. [Epub ahead of print]

PMID:
25500545
[PubMed - as supplied by publisher]
5.

A role for synapsin in FKBP51 modulation of stress responsiveness: Convergent evidence from animal and human studies.

Schmidt U, Buell DR, Ionescu IA, Gassen NC, Holsboer F, Cox MB, Novak B, Huber C, Hartmann J, Schmidt MV, Touma C, Rein T, Herrmann L.

Psychoneuroendocrinology. 2015 Feb;52:43-58. doi: 10.1016/j.psyneuen.2014.11.005. Epub 2014 Nov 11.

PMID:
25459892
[PubMed - in process]
6.

Association of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humans.

Gassen NC, Hartmann J, Zschocke J, Stepan J, Hafner K, Zellner A, Kirmeier T, Kollmannsberger L, Wagner KV, Dedic N, Balsevich G, Deussing JM, Kloiber S, Lucae S, Holsboer F, Eder M, Uhr M, Ising M, Schmidt MV, Rein T.

PLoS Med. 2014 Nov 11;11(11):e1001755. doi: 10.1371/journal.pmed.1001755. eCollection 2014 Nov.

PMID:
25386878
[PubMed - in process]
Free PMC Article
7.

Loratadine and analogues: discovery and preliminary structure-activity relationship of inhibitors of the amino acid transporter B(0)AT2.

Cuboni S, Devigny C, Hoogeland B, Strasser A, Pomplun S, Hauger B, Höfner G, Wanner KT, Eder M, Buschauer A, Holsboer F, Hausch F.

J Med Chem. 2014 Nov 26;57(22):9473-9. doi: 10.1021/jm501086v. Epub 2014 Nov 7.

PMID:
25318072
[PubMed - in process]
8.

Increased HPA axis response to psychosocial stress in remitted depression: the influence of coping style.

Höhne N, Poidinger M, Merz F, Pfister H, Brückl T, Zimmermann P, Uhr M, Holsboer F, Ising M.

Biol Psychol. 2014 Dec;103:267-75. doi: 10.1016/j.biopsycho.2014.09.008. Epub 2014 Sep 27.

PMID:
25263610
[PubMed - in process]
9.

Searching for non-genetic molecular and imaging PTSD risk and resilience markers: Systematic review of literature and design of the German Armed Forces PTSD biomarker study.

Schmidt U, Willmund GD, Holsboer F, Wotjak CT, Gallinat J, Kowalski JT, Zimmermann P.

Psychoneuroendocrinology. 2015 Jan;51:444-58. doi: 10.1016/j.psyneuen.2014.08.020. Epub 2014 Sep 4.

PMID:
25236294
[PubMed - in process]
10.

Mice selected for extremes in stress reactivity reveal key endophenotypes of major depression: a translational approach.

Heinzmann JM, Kloiber S, Ebling-Mattos G, Bielohuby M, Schmidt MV, Palme R, Holsboer F, Uhr M, Ising M, Touma C.

Psychoneuroendocrinology. 2014 Nov;49:229-43. doi: 10.1016/j.psyneuen.2014.07.008. Epub 2014 Jul 23.

PMID:
25123105
[PubMed - in process]
11.

Neural correlates of insight in dreaming and psychosis.

Dresler M, Wehrle R, Spoormaker VI, Steiger A, Holsboer F, Czisch M, Hobson JA.

Sleep Med Rev. 2014 Jun 25. pii: S1087-0792(14)00068-9. doi: 10.1016/j.smrv.2014.06.004. [Epub ahead of print] Review.

PMID:
25092021
[PubMed - as supplied by publisher]
12.

Hypothalamo-pituitary-adrenal axis activity evolves differentially in untreated versus treated multiple sclerosis.

Kümpfel T, Schwan M, Weber F, Holsboer F, Trenkwalder C, Then Bergh F.

Psychoneuroendocrinology. 2014 Jul;45:87-95. doi: 10.1016/j.psyneuen.2014.03.012. Epub 2014 Apr 2.

PMID:
24845180
[PubMed - indexed for MEDLINE]
13.

A polymorphism in the Crhr1 gene determines stress vulnerability in male mice.

Labermaier C, Kohl C, Hartmann J, Devigny C, Altmann A, Weber P, Arloth J, Quast C, Wagner KV, Scharf SH, Czibere L, Widner-Andrä R, Brenndörfer J, Landgraf R, Hausch F, Jones KA, Müller MB, Uhr M, Holsboer F, Binder EB, Schmidt MV.

Endocrinology. 2014 Jul;155(7):2500-10. doi: 10.1210/en.2013-1986. Epub 2014 Apr 28.

PMID:
24773341
[PubMed - indexed for MEDLINE]
14.

Dexamethasone stimulated gene expression in peripheral blood indicates glucocorticoid-receptor hypersensitivity in job-related exhaustion.

Menke A, Arloth J, Gerber M, Rex-Haffner M, Uhr M, Holsboer F, Binder EB, Holsboer-Trachsler E, Beck J.

Psychoneuroendocrinology. 2014 Jun;44:35-46. doi: 10.1016/j.psyneuen.2014.02.013. Epub 2014 Mar 3.

PMID:
24767618
[PubMed - indexed for MEDLINE]
15.

Redesigning antidepressant drug discovery.

Holsboer F.

Dialogues Clin Neurosci. 2014 Mar;16(1):5-7.

PMID:
24733967
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Blood mononuclear cell proteome suggests integrin and Ras signaling as critical pathways for antidepressant treatment response.

Martins-de-Souza D, Maccarrone G, Ising M, Kloiber S, Lucae S, Holsboer F, Turck CW.

Biol Psychiatry. 2014 Oct 1;76(7):e15-7. doi: 10.1016/j.biopsych.2014.01.022. Epub 2014 Feb 4. No abstract available.

PMID:
24607422
[PubMed - in process]
17.

Three-Year long-term outcome of 458 naturalistically treated inpatients with major depressive episode: severe relapse rates and risk factors.

Seemüller F, Meier S, Obermeier M, Musil R, Bauer M, Adli M, Kronmüller K, Holsboer F, Brieger P, Laux G, Bender W, Heuser I, Zeiler J, Gaebel W, Riedel M, Falkai P, Möller HJ.

Eur Arch Psychiatry Clin Neurosci. 2014 Oct;264(7):567-75. doi: 10.1007/s00406-014-0495-7. Epub 2014 Mar 4.

PMID:
24590257
[PubMed - in process]
18.

Evidence supporting the match/mismatch hypothesis of psychiatric disorders.

Santarelli S, Lesuis SL, Wang XD, Wagner KV, Hartmann J, Labermaier C, Scharf SH, Müller MB, Holsboer F, Schmidt MV.

Eur Neuropsychopharmacol. 2014 Jun;24(6):907-18. doi: 10.1016/j.euroneuro.2014.02.002. Epub 2014 Feb 15.

PMID:
24589292
[PubMed - indexed for MEDLINE]
19.

Are there meaningful biomarkers of treatment response for depression?

Breitenstein B, Scheuer S, Holsboer F.

Drug Discov Today. 2014 May;19(5):539-61. doi: 10.1016/j.drudis.2014.02.002. Epub 2014 Feb 21.

PMID:
24561326
[PubMed - in process]
20.

Bidirectional rescue of extreme genetic predispositions to anxiety: impact of CRH receptor 1 as epigenetic plasticity gene in the amygdala.

Sotnikov SV, Markt PO, Malik V, Chekmareva NY, Naik RR, Sah A, Singewald N, Holsboer F, Czibere L, Landgraf R.

Transl Psychiatry. 2014 Feb 11;4:e359. doi: 10.1038/tp.2013.127.

PMID:
24518397
[PubMed - in process]
Free PMC Article
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