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Items: 1 to 20 of 506

1.

Conserved 33-kb haplotype in the MHC class III region regulates chronic arthritis.

Yau AC, Tuncel J, Haag S, Norin U, Houtman M, Padyukov L, Holmdahl R.

Proc Natl Acad Sci U S A. 2016 Jun 14. pii: 201600567. [Epub ahead of print]

PMID:
27303036
2.

Collagen epitope expression on B cells is sufficient to confer tolerance to collagen-induced arthritis.

Andersson SE, Eneljung T, Tengvall S, Jirholt P, Stern A, Henningsson L, Liang B, Thorarinsdottir K, Kihlberg J, Holmdahl R, Mårtensson IL, Gustafsson K, Gjertsson I.

Arthritis Res Ther. 2016 Jun 14;18(1):140. doi: 10.1186/s13075-016-1037-7.

3.

A reduction in intracellular reactive oxygen species due to a mutation in NCF4 promotes autoimmune arthritis in mice.

Winter S, Hultqvist M, Laulund F, Holmdahl R.

Antioxid Redox Signal. 2016 May 26. [Epub ahead of print]

PMID:
27231144
4.

Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat.

Tuncel J, Haag S, Hoffmann MH, Yau AC, Hultqvist M, Olofsson P, Bäcklund J, Nandakumar KS, Weidner D, Fischer A, Leichsenring A, Lange F, Haase C, Lu S, Gulko PS, Steiner G, Holmdahl R.

PLoS One. 2016 May 26;11(5):e0155936. doi: 10.1371/journal.pone.0155936. eCollection 2016.

5.

Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis.

Tengvall S, Eneljung T, Jirholt P, Turesson O, Wing K, Holmdahl R, Kihlberg J, Stern A, Mårtensson IL, Henningsson L, Gustafsson K, Gjertsson I.

PLoS One. 2016 May 9;11(5):e0154630. doi: 10.1371/journal.pone.0154630. eCollection 2016.

6.

How well do ACPA discriminate and predict RA in the general population: a study based on 12 590 population-representative Swedish twins.

Hensvold AH, Frisell T, Magnusson PK, Holmdahl R, Askling J, Catrina AI.

Ann Rheum Dis. 2016 Apr 28. pii: annrheumdis-2015-208980. doi: 10.1136/annrheumdis-2015-208980. [Epub ahead of print]

PMID:
27125521
7.

Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood.

Klocke K, Sakaguchi S, Holmdahl R, Wing K.

Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):E2383-92. doi: 10.1073/pnas.1603892113. Epub 2016 Apr 11.

PMID:
27071130
8.

The SKG Mutation in ZAP-70 also Confers Arthritis Susceptibility in C57 Black Mouse Strains.

Guerard S, Boieri M, Hultqvist M, Holmdahl R, Wing K.

Scand J Immunol. 2016 Jul;84(1):3-11. doi: 10.1111/sji.12438.

9.

RA-relevant T cell responses to type II collagen can be influenced by post-translational modifications.

Chemin K, Pollastro S, Albrecht I, Holmdahl R, de Vries N, Malmström V.

Arthritis Rheumatol. 2016 Mar 4. doi: 10.1002/art.39660. [Epub ahead of print] No abstract available.

PMID:
26945919
10.

Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis.

Brink M, Hansson M, Mathsson-Alm L, Wijayatunga P, Verheul MK, Trouw LA, Holmdahl R, Rönnelid J, Klareskog L, Rantapää-Dahlqvist S.

Arthritis Res Ther. 2016 Feb 9;18:43. doi: 10.1186/s13075-016-0940-2.

11.

A Novel HLA-DRB1*10:01-Restricted T Cell Epitope From Citrullinated Type II Collagen Relevant to Rheumatoid Arthritis.

Chemin K, Pollastro S, James E, Ge C, Albrecht I, Herrath J, Gerstner C, Tandre K, Sampaio Rizzi T, Rönnblom L, Catrina A, Holmdahl R, Klareskog L, de Vries N, Malmström V.

Arthritis Rheumatol. 2016 May;68(5):1124-35. doi: 10.1002/art.39553.

PMID:
26713667
12.

Ncf1 polymorphism reveals oxidative regulation of autoimmune chronic inflammation.

Holmdahl R, Sareila O, Olsson LM, Bäckdahl L, Wing K.

Immunol Rev. 2016 Jan;269(1):228-47. doi: 10.1111/imr.12378. Review.

PMID:
26683156
13.

A novel long noncoding RNA Lnc-HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism.

Lan X, Yan J, Ren J, Zhong B, Li J, Li Y, Liu L, Yi J, Sun Q, Yang X, Sun J, Meng L, Zhu W, Holmdahl R, Li D, Lu S.

Hepatology. 2016 Jul;64(1):58-72. doi: 10.1002/hep.28391. Epub 2016 Jan 22.

PMID:
26663205
14.

Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism.

Wigerblad G, Bas DB, Fernades-Cerqueira C, Krishnamurthy A, Nandakumar KS, Rogoz K, Kato J, Sandor K, Su J, Jimenez-Andrade JM, Finn A, Bersellini Farinotti A, Amara K, Lundberg K, Holmdahl R, Jakobsson PJ, Malmström V, Catrina AI, Klareskog L, Svensson CI.

Ann Rheum Dis. 2016 Apr;75(4):730-8. doi: 10.1136/annrheumdis-2015-208094. Epub 2015 Nov 27.

15.

Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.

Sareila O, Hagert C, Rantakari P, Poutanen M, Holmdahl R.

PLoS One. 2015 Nov 3;10(11):e0141974. doi: 10.1371/journal.pone.0141974. eCollection 2015.

16.

Macrophage-derived reactive oxygen species protects against autoimmune priming with a defined polymeric adjuvant.

Shakya AK, Kumar A, Holmdahl R, Nandakumar KS.

Immunology. 2016 Jan;147(1):125-32. doi: 10.1111/imm.12546. Epub 2015 Nov 24.

PMID:
26455429
17.

An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting.

van Heemst J, Trouw LA, Nogueira L, van Steenbergen HW, van der Helm-van Mil AH, Allaart CF, Serre G, Holmdahl R, Huizinga TW, Toes RE, van der Woude D.

Arthritis Res Ther. 2015 Oct 5;17:276. doi: 10.1186/s13075-015-0786-z.

18.

System A amino acid transporters regulate glutamine uptake and attenuate antibody-mediated arthritis.

Raposo B, Vaartjes D, Ahlqvist E, Nandakumar KS, Holmdahl R.

Immunology. 2015 Dec;146(4):607-17. doi: 10.1111/imm.12531. Epub 2015 Oct 5.

PMID:
26346312
19.

Methylcholanthrene-Induced Sarcomas Develop Independently from NOX2-Derived ROS.

Ligtenberg MA, Çınar Ö, Holmdahl R, Mougiakakos D, Kiessling R.

PLoS One. 2015 Jun 15;10(6):e0129786. doi: 10.1371/journal.pone.0129786. eCollection 2015.

20.

Associations of antibodies against citrullinated peptides with human leukocyte antigen-shared epitope and smoking prior to the development of rheumatoid arthritis.

Kokkonen H, Brink M, Hansson M, Lassen E, Mathsson-Alm L, Holmdahl R, Rönnelid J, Klareskog L, Rantapää-Dahlqvist S.

Arthritis Res Ther. 2015 May 20;17:125. doi: 10.1186/s13075-015-0638-x.

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